Cardiomyopathy in Duchenne muscular dystrophy: pathogenesis and therapeutics - PubMed (original) (raw)

Review

Cardiomyopathy in Duchenne muscular dystrophy: pathogenesis and therapeutics

Abdallah Fayssoil et al. Heart Fail Rev. 2010 Jan.

Abstract

Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder caused by the absence of dystrophin, a sarcolemmal protein which links the cytoskeleton to the extracellular matrix by interacting with a large number of proteins. Heart failure is a classic complication of this disease. The authors review the pathogenesis and therapeutics of cardiac involvement in DMD.

PubMed Disclaimer

Similar articles

• Cardiac consequences to skeletal muscle-centric therapeutics for Duchenne muscular dystrophy.
  Townsend D, Yasuda S, Chamberlain J, Metzger JM. Townsend D, et al. Trends Cardiovasc Med. 2009 Feb;19(2):50-55. doi: 10.1016/j.tcm.2009.04.006. Trends Cardiovasc Med. 2009. PMID: 19577712
• Dystrophin-Deficient Cardiomyopathy.
  Kamdar F, Garry DJ. Kamdar F, et al. J Am Coll Cardiol. 2016 May 31;67(21):2533-46. doi: 10.1016/j.jacc.2016.02.081. J Am Coll Cardiol. 2016. PMID: 27230049 Review.
• Cardiac Involvement in Duchenne Muscular Dystrophy and Related Dystrophinopathies.
  Mavrogeni SI, Markousis-Mavrogenis G, Papavasiliou A, Papadopoulos G, Kolovou G. Mavrogeni SI, et al. Methods Mol Biol. 2018;1687:31-42. doi: 10.1007/978-1-4939-7374-3_3. Methods Mol Biol. 2018. PMID: 29067654
• [Management of myocardial damage in muscular dystrophy].
  Tamura T. Tamura T. Brain Nerve. 2011 Nov;63(11):1217-28. Brain Nerve. 2011. PMID: 22068474 Review. Japanese.
• Pharmacological management of dilated cardiomyopathy in Duchenne muscular dystrophy: A systematic review.
  Haddad CN, Ali S, Stephanou D, Assakura MS, Sahagian L, Trogkanis E. Haddad CN, et al. Hellenic J Cardiol. 2023 Nov-Dec;74:58-64. doi: 10.1016/j.hjc.2023.06.007. Epub 2023 Jul 3. Hellenic J Cardiol. 2023. PMID: 37406964 Review.

Cited by

• The Role of MicroRNA in the Pathogenesis of Duchenne Muscular Dystrophy.
  Kiełbowski K, Bakinowska E, Procyk G, Ziętara M, Pawlik A. Kiełbowski K, et al. Int J Mol Sci. 2024 Jun 1;25(11):6108. doi: 10.3390/ijms25116108. Int J Mol Sci. 2024. PMID: 38892293 Free PMC article. Review.
• Is Cardiac Transplantation Still a Contraindication in Patients with Muscular Dystrophy-Related End-Stage Dilated Cardiomyopathy? A Systematic Review.
  Politano L. Politano L. Int J Mol Sci. 2024 May 13;25(10):5289. doi: 10.3390/ijms25105289. Int J Mol Sci. 2024. PMID: 38791328 Free PMC article. Review.
• Decoding the Gene Regulatory Network of Muscle Stem Cells in Mouse Duchenne Muscular Dystrophy: Revelations from Single-Nuclei RNA Sequencing Analysis.
  Shen Y, Kim IM, Tang Y. Shen Y, et al. Int J Mol Sci. 2023 Aug 5;24(15):12463. doi: 10.3390/ijms241512463. Int J Mol Sci. 2023. PMID: 37569835 Free PMC article.
• Modeling Duchenne Muscular Dystrophy Cardiomyopathy with Patients' Induced Pluripotent Stem-Cell-Derived Cardiomyocytes.
  Eisen B, Binah O. Eisen B, et al. Int J Mol Sci. 2023 May 12;24(10):8657. doi: 10.3390/ijms24108657. Int J Mol Sci. 2023. PMID: 37240001 Free PMC article. Review.

References

1. 1. Nat Med. 2006 Oct;12(10):1147-50 - PubMed
2. 1. Science. 2003 Jul 25;301(5632):487-92 - PubMed
3. 1. Clin Exp Pharmacol Physiol. 2006 Jul;33(7):657-62 - PubMed
4. 1. Cardiovasc Res. 2001 Jun;50(3):509-15 - PubMed
5. 1. Am J Pathol. 2003 Oct;163(4):1663-75 - PubMed

Publication types

MeSH terms

Substances

LinkOut - more resources

• Full Text Sources

  • Springer

• Other Literature Sources

  • The Lens - Patent Citations Database

• Medical

  • MedlinePlus Health Information