Incorporation of essential oil in alginate microparticles by multiple emulsion/ionic gelation process - PubMed (original) (raw)
Incorporation of essential oil in alginate microparticles by multiple emulsion/ionic gelation process
Seyede Marzieh Hosseini et al. Int J Biol Macromol. 2013 Nov.
Abstract
In this study, an o/w/o multiple emulsion/ionic gelation method was developed for production of alginate microparticles loaded with Satureja hortensis essential oil (SEO). It was found that the essential oil concentration has significant influence on encapsulation efficiency (EE), loading capacity (LC) and size of microparticles. The values of EE, LC and particle mean diameter were about 52-66%, 20-26%, and 47-117 μm, respectively, when the initial SEO content was 1-3% (v/v) .The essential oil-loaded microparticles were porous, as displayed by scanning electron micrograph. The presence of SEO in alginate microparticles was confirmed by Fourier transform-infrared (FT-IR) spectroscopy and differential scanning calorimetry (DSC) analyses. SEO-loaded microparticles showed good antioxidant (with DPPH radical scavenging activity of 40.7-73.5%) and antibacterial properties; this effect was greatly improved when the concentration of SEO was 3% (v/v). S. aureus was found to be the most sensitive bacterium to SEO and showed a highest inhibition zone of 304.37 mm(2) in the microparticles incorporated with 3% (v/v) SEO. In vitro release studies showed an initial burst release and followed by a slow release. In addition, the release of SEO from the microparticles followed Fickian diffusion with acceptable release.
Keywords: Alginate; Essential oil; Microparticle; Multiple emulsion; Satureja hortensis.
Copyright © 2013 Elsevier B.V. All rights reserved.
Similar articles
- Chitosan oligosaccharide as prospective cross-linking agent for naproxen-loaded Ca-alginate microparticles with improved pH sensitivity.
Čalija B, Milić J, Cekić N, Krajišnik D, Daniels R, Savić S. Čalija B, et al. Drug Dev Ind Pharm. 2013 Jan;39(1):77-88. doi: 10.3109/03639045.2012.658813. Epub 2012 Feb 18. Drug Dev Ind Pharm. 2013. PMID: 22339172 - In vitro release and biological activities of Carum copticum essential oil (CEO) loaded chitosan nanoparticles.
Esmaeili A, Asgari A. Esmaeili A, et al. Int J Biol Macromol. 2015 Nov;81:283-90. doi: 10.1016/j.ijbiomac.2015.08.010. Epub 2015 Aug 7. Int J Biol Macromol. 2015. PMID: 26257380 - Alginate/cashew gum nanoparticles for essential oil encapsulation.
de Oliveira EF, Paula HC, de Paula RC. de Oliveira EF, et al. Colloids Surf B Biointerfaces. 2014 Jan 1;113:146-51. doi: 10.1016/j.colsurfb.2013.08.038. Epub 2013 Sep 5. Colloids Surf B Biointerfaces. 2014. PMID: 24077112 - Development and evaluation of pH-sensitive sodium alginate/chitosan microparticles containing the antituberculosis drug rifampicin.
Lacerda L, Parize AL, Fávere V, Laranjeira MC, Stulzer HK. Lacerda L, et al. Mater Sci Eng C Mater Biol Appl. 2014 Jun 1;39:161-7. doi: 10.1016/j.msec.2014.01.054. Epub 2014 Feb 10. Mater Sci Eng C Mater Biol Appl. 2014. PMID: 24863212 Review. - Preparation of chitosan/alginate/calcium complex microparticles loaded with lactoferrin and their efficacy on carrageenan-induced edema in rats.
Onishi H, Koyama K, Sakata O, Machida Y. Onishi H, et al. Drug Dev Ind Pharm. 2010 Aug;36(8):879-84. doi: 10.3109/03639040903567109. Drug Dev Ind Pharm. 2010. PMID: 20345284 Review.
Cited by
- Role and Merits of Green Based Nanocarriers in Cancer Treatment.
Elbagory AM, Marima RM, Dlamini Z. Elbagory AM, et al. Cancers (Basel). 2021 Nov 13;13(22):5686. doi: 10.3390/cancers13225686. Cancers (Basel). 2021. PMID: 34830840 Free PMC article. Review. - Hybrid Microcapsules for Encapsulation and Controlled Release of Rosemary Essential Oil.
Berraaouan D, Essifi K, Addi M, Hano C, Fauconnier ML, Tahani A. Berraaouan D, et al. Polymers (Basel). 2023 Feb 7;15(4):823. doi: 10.3390/polym15040823. Polymers (Basel). 2023. PMID: 36850108 Free PMC article. - Use of Plant Proteins as Microencapsulating Agents of Bioactive Compounds Extracted from Annatto Seeds (Bixa orellana L.).
Quintero Quiroz J, Velazquez V, Corrales-Garcia LL, Torres JD, Delgado E, Ciro G, Rojas J. Quintero Quiroz J, et al. Antioxidants (Basel). 2020 Apr 13;9(4):310. doi: 10.3390/antiox9040310. Antioxidants (Basel). 2020. PMID: 32294926 Free PMC article. - Characterization of alginate extracted from Sargassum latifolium and its use in Chlorella vulgaris growth promotion and riboflavin drug delivery.
Dalal SR, Hussein MH, El-Naggar NE, Mostafa SI, Shaaban-Dessuuki SA. Dalal SR, et al. Sci Rep. 2021 Aug 18;11(1):16741. doi: 10.1038/s41598-021-96202-0. Sci Rep. 2021. PMID: 34408229 Free PMC article. - Preparation, Characterization, In Vitro Release, and Antibacterial Activity of Oregano Essential Oil Chitosan Nanoparticles.
Ma Y, Liu P, Ye K, He Y, Chen S, Yuan A, Chen F, Yang W. Ma Y, et al. Foods. 2022 Nov 22;11(23):3756. doi: 10.3390/foods11233756. Foods. 2022. PMID: 36496563 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources