Cigarette smoking and risk of nuclear cataracts - PubMed (original) (raw)
Cigarette smoking and risk of nuclear cataracts
S West et al. Arch Ophthalmol. 1989 Aug.
Abstract
The current study was undertaken to assess the relationship of smoking to the risk of lens opacities. The risk was evaluated separately for nuclear and cortical opacities and for both types together. We studied 838 watermen in Maryland by detailed ocular examination for the presence and severity of each cataract type. All subjects were interviewed regarding smoking history, and a cumulative smoking dose was calculated. The results suggest a significantly increased risk of pure nuclear opacities associated with cigarette smoking. The increase in smoking dose was associated with increasing severity of nuclear opacity. The risk of nuclear opacities increased with increasing cigarette dose and decreased if the subject had quit smoking. The effect of smoking was most striking in those less than 80 years old. No increased risk of nuclear opacities was observed with earlier age when smoking started, after adjusting for dose and cessation of smoking. Further investigations are warranted on the biochemical and physical damage to the nucleus of the lens from smoking cigarettes.
Similar articles
- A longitudinal study of body mass index and lens opacities. The Framingham Studies.
Hiller R, Podgor MJ, Sperduto RD, Nowroozi L, Wilson PW, D'Agostino RB, Colton T. Hiller R, et al. Ophthalmology. 1998 Jul;105(7):1244-50. doi: 10.1016/s0161-6420(98)97029-4. Ophthalmology. 1998. PMID: 9663229 - NASA study of cataract in astronauts (NASCA). Report 1: Cross-sectional study of the relationship of exposure to space radiation and risk of lens opacity.
Chylack LT Jr, Peterson LE, Feiveson AH, Wear ML, Manuel FK, Tung WH, Hardy DS, Marak LJ, Cucinotta FA. Chylack LT Jr, et al. Radiat Res. 2009 Jul;172(1):10-20. doi: 10.1667/RR1580.1. Radiat Res. 2009. PMID: 19580503 - Cigarette smoking and the risk of development of lens opacities. The Framingham studies.
Hiller R, Sperduto RD, Podgor MJ, Wilson PW, Ferris FL 3rd, Colton T, D'Agostino RB, Roseman MJ, Stockman ME, Milton RC. Hiller R, et al. Arch Ophthalmol. 1997 Sep;115(9):1113-8. doi: 10.1001/archopht.1997.01100160283003. Arch Ophthalmol. 1997. PMID: 9298050 - Cortical and subcapsular cataracts: significance of physical forces.
Pau H. Pau H. Ophthalmologica. 2006;220(1):1-5. doi: 10.1159/000089267. Ophthalmologica. 2006. PMID: 16374041 Review. - Age-related nuclear cataract-oxidation is the key.
Truscott RJ. Truscott RJ. Exp Eye Res. 2005 May;80(5):709-25. doi: 10.1016/j.exer.2004.12.007. Exp Eye Res. 2005. PMID: 15862178 Review.
Cited by
- A longitudinal analysis of factors associated with age-related cataract among older Australian women: a cohort study of 7851 older Australian women 79-90 years.
Hambisa MT, Dolja-Gore X, Byles JE. Hambisa MT, et al. Ir J Med Sci. 2023 Jun;192(3):1525-1536. doi: 10.1007/s11845-022-03130-7. Epub 2022 Aug 17. Ir J Med Sci. 2023. PMID: 35976564 Free PMC article. - The more smoking the more cataract: A study on smoking, snus use and cataract in a Swedish population.
Nordström M, Zetterberg M, Torén K, Schiöler L, Holm M. Nordström M, et al. Acta Ophthalmol. 2025 Feb;103(1):77-84. doi: 10.1111/aos.16770. Epub 2024 Oct 18. Acta Ophthalmol. 2025. PMID: 39422508 Free PMC article. - [Color vision testing in patients with diabetes mellitus and arterial hypertension].
Lüthke S, Welters A, Kropf S, Böckelmann I. Lüthke S, et al. Ophthalmologe. 2010 Oct;107(10):923-9. doi: 10.1007/s00347-010-2169-9. Ophthalmologe. 2010. PMID: 20532521 German. - Early lens aging is accelerated in subjects with a high risk of ischemic heart disease: an epidemiologic study.
Kessel L, Jørgensen T, Glümer C, Larsen M. Kessel L, et al. BMC Ophthalmol. 2006 Apr 18;6:16. doi: 10.1186/1471-2415-6-16. BMC Ophthalmol. 2006. PMID: 16618373 Free PMC article. - Selenium intake help prevent age-related cataract formation: Evidence from NHANES 2001-2008.
Xu B, Liu Z, Zhao J, Yu Z. Xu B, et al. Front Nutr. 2023 Jan 27;10:1042893. doi: 10.3389/fnut.2023.1042893. eCollection 2023. Front Nutr. 2023. PMID: 36776608 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical