Introduction to RNA Vaccines - PubMed (original) (raw)
Review
Introduction to RNA Vaccines
Thomas Kramps et al. Methods Mol Biol. 2017.
Abstract
RNA vaccines are attractive, because they exhibit characteristics of subunit vaccines and live-attenuated vectors, including flexible production and induction of both humoral and cellular immunity. While human proof-of-concept for RNA vaccines is still pending, the nascent field of RNA therapeutics has already attracted substantial industry and government funding as well as record investments of private venture capital. Most recently, the WHO acknowledged messenger RNA (mRNA) as a new therapeutic class. In this chapter, we briefly review key developments in RNA vaccines and outline the contents of this volume of Methods in Molecular Biology.
Keywords: Messenger RNA; RNA vaccine; RNA virus vector; Replicon; Self-amplifying RNA.
Similar articles
- RNA-based vaccines.
Ulmer JB, Mason PW, Geall A, Mandl CW. Ulmer JB, et al. Vaccine. 2012 Jun 22;30(30):4414-8. doi: 10.1016/j.vaccine.2012.04.060. Epub 2012 Apr 28. Vaccine. 2012. PMID: 22546329 Review. - Introduction to RNA Vaccines Post COVID-19.
Kramps T. Kramps T. Methods Mol Biol. 2024;2786:1-22. doi: 10.1007/978-1-0716-3770-8_1. Methods Mol Biol. 2024. PMID: 38814388 Review. - Polyethylenimine-based polyplex delivery of self-replicating RNA vaccines.
Démoulins T, Milona P, Englezou PC, Ebensen T, Schulze K, Suter R, Pichon C, Midoux P, Guzmán CA, Ruggli N, McCullough KC. Démoulins T, et al. Nanomedicine. 2016 Apr;12(3):711-722. doi: 10.1016/j.nano.2015.11.001. Epub 2015 Dec 1. Nanomedicine. 2016. PMID: 26592962 - T cell vaccinology: exploring the known unknowns.
Burchill MA, Tamburini BA, Pennock ND, White JT, Kurche JS, Kedl RM. Burchill MA, et al. Vaccine. 2013 Jan 2;31(2):297-305. doi: 10.1016/j.vaccine.2012.10.096. Epub 2012 Nov 6. Vaccine. 2013. PMID: 23137843 Free PMC article. Review. - Messenger RNA vaccine based on recombinant MS2 virus-like particles against prostate cancer.
Li J, Sun Y, Jia T, Zhang R, Zhang K, Wang L. Li J, et al. Int J Cancer. 2014 Apr 1;134(7):1683-94. doi: 10.1002/ijc.28482. Epub 2013 Oct 8. Int J Cancer. 2014. PMID: 24105486
Cited by
- Determination of linearized pDNA template in mRNA production process using HPLC.
Leban M, Vodopivec Seravalli T, Hauer M, Böhm E, Mencin N, Potušek S, Thompson A, Trontelj J, Štrancar A, Sekirnik R. Leban M, et al. Anal Bioanal Chem. 2024 Apr;416(10):2389-2398. doi: 10.1007/s00216-024-05204-0. Epub 2024 Mar 5. Anal Bioanal Chem. 2024. PMID: 38438547 - Mucin1 as a potential molecule for cancer immunotherapy and targeted therapy.
Tong X, Dong C, Liang S. Tong X, et al. J Cancer. 2024 Jan 1;15(1):54-67. doi: 10.7150/jca.88261. eCollection 2024. J Cancer. 2024. PMID: 38164273 Free PMC article. Review. - Malaria & mRNA Vaccines: A Possible Salvation from One of the Most Relevant Infectious Diseases of the Global South.
Borkens Y. Borkens Y. Acta Parasitol. 2023 Dec;68(4):916-928. doi: 10.1007/s11686-023-00712-y. Epub 2023 Oct 12. Acta Parasitol. 2023. PMID: 37828249 Free PMC article. - Circular RNA vaccine in disease prevention and treatment.
Niu D, Wu Y, Lian J. Niu D, et al. Signal Transduct Target Ther. 2023 Sep 11;8(1):341. doi: 10.1038/s41392-023-01561-x. Signal Transduct Target Ther. 2023. PMID: 37691066 Free PMC article. Review. - mRNA-From COVID-19 Treatment to Cancer Immunotherapy.
Krause W. Krause W. Biomedicines. 2023 Jan 22;11(2):308. doi: 10.3390/biomedicines11020308. Biomedicines. 2023. PMID: 36830845 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical