The effect of simulated flash heating pasteurisation and Holder pasteurisation on human milk oligosaccharides - PubMed (original) (raw)

Comparative Study

. 2017 Aug;37(3):204-209.

doi: 10.1080/20469047.2017.1293869. Epub 2017 Mar 6.

Affiliations

Comparative Study

The effect of simulated flash heating pasteurisation and Holder pasteurisation on human milk oligosaccharides

Brodie Daniels et al. Paediatr Int Child Health. 2017 Aug.

Abstract

Background: Human milk oligosaccharides (HMOs) have important protective functions in human milk. A low-cost remote pasteurisation temperature-monitoring system has been designed using FoneAstra, a cell phone-based networked sensing system to monitor simulated flash heat pasteurisation.

Aim: To compare the pasteurisation effect on HMOs of the FoneAstra FH method with the current Sterifeed Holder method used by human milk banks.

Methods: Donor human milk samples (n = 48) were obtained from a human milk bank and pasteurised using the two pasteurisation methods. HMOs were purified from samples and labelled before separation using high-performance liquid chromatography. Concentrations of total HMOs, sialylated and fucosylated HMOs and individual HMOs using the two pasteurisation methods were compared using repeated-measures ANOVA.

Results: The study demonstrated no difference in total concentration of HMOs between the two pasteurisation methods and a small but significant increase in the total concentration of HMOs regardless of pasteurisation methods compared with controls (unpasteurised samples) (p<0.0001).

Conclusion: The FoneAstra FH pasteurisation system does not negatively affect oligosaccharides in human milk and therefore is a possible alternative for providing safely sterilised human milk for low- and middle-income countries.

Keywords: Human milk; human milk banking; human milk oligosaccharides; pasteurisation.

PubMed Disclaimer

Similar articles

Cited by

Publication types

MeSH terms

Substances

LinkOut - more resources