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References
Carr AC, Rosengrave PC, Bayer S, et al. Hypovitaminosis C and vitamin C deficiency in critically ill patients despite recommended enteral and parenteral intakes. Crit Care. 2017;21:300. doi: 10.1186/s13054-017-1891-y. - DOI - PMC - PubMed
Borrelli E, Roux-Lombard P, Grau GE, et al. Plasma concentrations of cytokines, their soluble receptors, and antioxidant vitamins can predict the development of multiple organ failure in patients at risk. Crit Care Med. 1996;24:392–7. doi: 10.1097/00003246-199603000-00006. - DOI - PubMed
Victor VM, Guayerbas N, Puerto M, et al. Changes in the ascorbic acid levels of peritoneal lymphocytes and macrophages of mice with endotoxin-induced oxidative stress. Free Radic Res. 2001;35:907–16. doi: 10.1080/10715760100301401. - DOI - PubMed
Evans-Olders R, Eintracht S, Hoffer LJ. Metabolic origin of hypovitaminosis C in acutely hospitalized patients. Nutrition. 2010;26:1070–4. doi: 10.1016/j.nut.2009.08.015. - DOI - PubMed
De Grooth HM, Spoeistra-de Man AM, Oudermans-van Straaten HM. Early plasma vitamin C concentration, organ dysfunction and ICU mortality. Intensive Care Med. 2014;40:S199.