MiR-17-92 cluster and immunity - PubMed (original) (raw)
Review
. 2019 Jan;118(1 Pt 1):2-6.
doi: 10.1016/j.jfma.2018.04.013. Epub 2018 May 29.
Affiliations
- PMID: 29857952
- DOI: 10.1016/j.jfma.2018.04.013
Free article
Review
MiR-17-92 cluster and immunity
George Kuo et al. J Formos Med Assoc. 2019 Jan.
Free article
Abstract
MicroRNAs (MiR, MiRNA) are small single-stranded non-coding RNAs that play an important role in the regulation of gene expression. MircoRNAs exert their effect by binding to complementary nucleotide sequences of the targeted messenger RNA, thus forming an RNA-induced silencing complex. The mircoRNA-17-92 cluster encoded by the miR-17-92 host gene is first found in malignant B-cell lymphoma. Recent research identifies the miR-17-92 cluster as a crucial player in the development of the immune system, the heart, the lung, and oncogenic events. In light of the miR-17-92 cluster's increasing role in regulating the immune system, our review will discuss the latest knowledge regarding its involvement in cells of both innate and adaptive immunity, including B cells, subsets of T cells such as Th1, Th2, T follicular helper cells, regulatory T cells, monocytes/macrophages, NK cells, and dendritic cells, and the possible targets that are regulated by its members.
Keywords: Immune regulation; MicroRNA-17-92 cluster; Proliferation.
Copyright © 2018. Published by Elsevier B.V.
Similar articles
- Recent findings regarding let-7 in immunity.
Jiang S. Jiang S. Cancer Lett. 2018 Oct 10;434:130-131. doi: 10.1016/j.canlet.2018.07.027. Epub 2018 Jul 24. Cancer Lett. 2018. PMID: 30053607 Review. - Regulation of the MIR155 host gene in physiological and pathological processes.
Elton TS, Selemon H, Elton SM, Parinandi NL. Elton TS, et al. Gene. 2013 Dec 10;532(1):1-12. doi: 10.1016/j.gene.2012.12.009. Epub 2012 Dec 14. Gene. 2013. PMID: 23246696 Review. - Profiling microRNA expression in bovine alveolar macrophages using RNA-seq.
Vegh P, Foroushani AB, Magee DA, McCabe MS, Browne JA, Nalpas NC, Conlon KM, Gordon SV, Bradley DG, MacHugh DE, Lynn DJ. Vegh P, et al. Vet Immunol Immunopathol. 2013 Oct 1;155(4):238-44. doi: 10.1016/j.vetimm.2013.08.004. Epub 2013 Aug 24. Vet Immunol Immunopathol. 2013. PMID: 24021155 - Diverse functions of miR-17-92 cluster microRNAs in T helper cells.
Baumjohann D. Baumjohann D. Cancer Lett. 2018 Jun 1;423:147-152. doi: 10.1016/j.canlet.2018.02.035. Epub 2018 Feb 28. Cancer Lett. 2018. PMID: 29499238 Review. - Pregnancy-Induced Changes in microRNA Expression in Multiple Sclerosis.
Søndergaard HB, Airas L, Christensen JR, Nielsen BR, Börnsen L, Oturai A, Sellebjerg F. Søndergaard HB, et al. Front Immunol. 2021 Jan 28;11:552101. doi: 10.3389/fimmu.2020.552101. eCollection 2020. Front Immunol. 2021. PMID: 33584638 Free PMC article.
Cited by
- MVNMDA: A Multi-View Network Combing Semantic and Global Features for Predicting miRNA-Disease Association.
Yang C, Wang Z, Zhang S, Li X, Wang X, Liu J, Li R, Zeng S. Yang C, et al. Molecules. 2023 Dec 31;29(1):230. doi: 10.3390/molecules29010230. Molecules. 2023. PMID: 38202814 Free PMC article. - The miR-17-92 cluster in cardiac health and disease.
Cao Y, Zheng M, Sewani MA, Wang J. Cao Y, et al. Birth Defects Res. 2024 Jan;116(1):e2273. doi: 10.1002/bdr2.2273. Epub 2023 Nov 20. Birth Defects Res. 2024. PMID: 37984445 Free PMC article. Review. - Role of microRNAs in Chronic Lymphocytic Leukemia.
Autore F, Ramassone A, Stirparo L, Pagotto S, Fresa A, Innocenti I, Visone R, Laurenti L. Autore F, et al. Int J Mol Sci. 2023 Aug 5;24(15):12471. doi: 10.3390/ijms241512471. Int J Mol Sci. 2023. PMID: 37569845 Free PMC article. Review. - Functional and Clinical Significance of Dysregulated microRNAs in Liver Cancer.
Huang PS, Liao CJ, Huang YH, Yeh CT, Chen CY, Tang HC, Chang CC, Lin KH. Huang PS, et al. Cancers (Basel). 2021 Oct 26;13(21):5361. doi: 10.3390/cancers13215361. Cancers (Basel). 2021. PMID: 34771525 Free PMC article. Review. - A Regulator of Metabolic Reprogramming: MicroRNA Let-7.
Jiang S. Jiang S. Transl Oncol. 2019 Jul;12(7):1005-1013. doi: 10.1016/j.tranon.2019.04.013. Epub 2019 May 22. Transl Oncol. 2019. PMID: 31128429 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources