Combining the wisdoms of traditional medicine with cutting-edge science and technology at the forefront of medical sciences - PubMed (original) (raw)
Combining the wisdoms of traditional medicine with cutting-edge science and technology at the forefront of medical sciences
Thomas Efferth et al. Phytomedicine. 2019 Nov.
Abstract
Background: A central topic is to bring traditional medicine to a new horizon by integrating the latest advances in genomic, metabolomic, and system biological approaches, in order to re-examine the wisdom and knowledge of traditional Chinese medicine (TCM) and other traditional medicines.
Purpose: A new consortium has been formed at a conference of the Harvard Medical School, Boston, on October 29-30, 2018. The main goal was to build a collaborative platform for the scientific investigation of traditional medicine with cutting edge sciences and technologies at the forefront of biomedicine.
Results: Traditional medicines are largely experience-based, but the scientific basis is largely non-satisfactory. Therefore, the transformation from experience-based to evidence-based medicine would be an important step forward. The consortium covers three main fields: TCM diagnostics, acupuncture and TCM pharmacology. Diseases occur because of regulatory imbalances of holistic physiological display and genetic information/expression related to systems biology and energy consumption/release (e.g. cold and hot) within body. As organs are interconnected by meridians, affecting the meridians by acupuncture and medicinal herbs restores healthy organ function and body balance. There are two concepts in herbal medicine: The traditional way is based on complex herbal mixtures. The second concept is related to Western pharmacological drug development including the isolation of bioactive phytochemicals, which are subjected to preclinical and clinical investigations.
Conclusion: Development of collaborative scientific project to integrate the best of both worlds - Western and Eastern medicine into a "One World Integrative Medicine" for the sake of patients worldwide.
Keywords: Integrative medicine; Systems biology; Traditional medicine.
Copyright © 2019 Elsevier GmbH. All rights reserved.
Similar articles
- Omic techniques in systems biology approaches to traditional Chinese medicine research: present and future.
Buriani A, Garcia-Bermejo ML, Bosisio E, Xu Q, Li H, Dong X, Simmonds MS, Carrara M, Tejedor N, Lucio-Cazana J, Hylands PJ. Buriani A, et al. J Ethnopharmacol. 2012 Apr 10;140(3):535-44. doi: 10.1016/j.jep.2012.01.055. Epub 2012 Feb 8. J Ethnopharmacol. 2012. PMID: 22342380 Review. - Traditional Chinese herbal medicine at the forefront battle against COVID-19: Clinical experience and scientific basis.
Lee DYW, Li QY, Liu J, Efferth T. Lee DYW, et al. Phytomedicine. 2021 Jan;80:153337. doi: 10.1016/j.phymed.2020.153337. Epub 2020 Sep 28. Phytomedicine. 2021. PMID: 33221457 Free PMC article. - Good practice in reviewing and publishing studies on herbal medicine, with special emphasis on traditional Chinese medicine and Chinese materia medica.
Chan K, Shaw D, Simmonds MS, Leon CJ, Xu Q, Lu A, Sutherland I, Ignatova S, Zhu YP, Verpoorte R, Williamson EM, Duez P. Chan K, et al. J Ethnopharmacol. 2012 Apr 10;140(3):469-75. doi: 10.1016/j.jep.2012.01.038. Epub 2012 Feb 11. J Ethnopharmacol. 2012. PMID: 22330011 Review. - Trends in herbgenomics.
Xin T, Zhang Y, Pu X, Gao R, Xu Z, Song J. Xin T, et al. Sci China Life Sci. 2019 Mar;62(3):288-308. doi: 10.1007/s11427-018-9352-7. Epub 2018 Aug 14. Sci China Life Sci. 2019. PMID: 30128965 - Pharmacological tools for the development of traditional Chinese medicine.
Liu X, Wu WY, Jiang BH, Yang M, Guo DA. Liu X, et al. Trends Pharmacol Sci. 2013 Nov;34(11):620-8. doi: 10.1016/j.tips.2013.09.004. Epub 2013 Oct 16. Trends Pharmacol Sci. 2013. PMID: 24139610 Review.
Cited by
- Berberine exerts its antineoplastic effects by reversing the Warburg effect via downregulation of the Akt/mTOR/GLUT1 signaling pathway.
Guo XH, Jiang SS, Zhang LL, Hu J, Edelbek D, Feng YQ, Yang ZX, Hu PC, Zhong H, Yang GH, Yang F. Guo XH, et al. Oncol Rep. 2021 Dec;46(6):253. doi: 10.3892/or.2021.8204. Epub 2021 Oct 13. Oncol Rep. 2021. PMID: 34643248 Free PMC article. - Potential Mechanism of S. baicalensis on Lipid Metabolism Explored via Network Pharmacology and Untargeted Lipidomics.
Ge PY, Qi YY, Qu SY, Zhao X, Ni SJ, Yao ZY, Guo R, Yang NY, Zhang QC, Zhu HX. Ge PY, et al. Drug Des Devel Ther. 2021 May 4;15:1915-1930. doi: 10.2147/DDDT.S301679. eCollection 2021. Drug Des Devel Ther. 2021. PMID: 33976541 Free PMC article. - MAPLE Coatings Embedded with Essential Oil-Conjugated Magnetite for Anti-Biofilm Applications.
Gherasim O, Popescu RC, Grumezescu V, Mogoșanu GD, Mogoantă L, Iordache F, Holban AM, Vasile BȘ, Bîrcă AC, Oprea OC, Grumezescu AM, Andronescu E. Gherasim O, et al. Materials (Basel). 2021 Mar 25;14(7):1612. doi: 10.3390/ma14071612. Materials (Basel). 2021. PMID: 33806228 Free PMC article. - Pharmacists' perspectives on traditional, complementary, and integrative medicine in Japan with special reference to Kampo medicines: an internet survey with preliminary interviews.
Motoo Y, Yukawa K, Hisamura K, Arai I. Motoo Y, et al. J Pharm Health Care Sci. 2022 Mar 1;8(1):7. doi: 10.1186/s40780-022-00238-x. J Pharm Health Care Sci. 2022. PMID: 35227321 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Research Materials