Multifunctional Hydroxyapatite Coated with Arthemisia absinthium Composites - PubMed (original) (raw)

doi: 10.3390/molecules25020413.

Simona Liliana Iconaru 2, Andreea Groza 3, Carmen Cimpeanu 4, Gabriel Predoi 1, Liliana Ghegoiu 2, Monica Luminita Badea 2 5, Mariana Carmen Chifiriuc 6 7, Luminita Marutescu 6 7, Roxana Trusca 8, Ciprian Florin Furnaris 1, Claudiu Stefan Turculet 9, Dorin Valter Enache 10, Daniela Predoi 2

Affiliations

• PMID: 31963829
• PMCID: PMC7024177
• DOI: 10.3390/molecules25020413

Multifunctional Hydroxyapatite Coated with Arthemisia absinthium Composites

Mariana Stefania Raita et al. Molecules. 2020.

Abstract

There is significant research showing that essential oils extracted from the plants have antibacterial effects. The purpose of this study was to develop a biocomposite based on hydroxyapatite coated with Artemisia absinthium essential oil and to highlight its antibacterial activity. Therefore, present studies are aimed at developing new materials combining hydroxyapatite with Artemisia absinthium essential oil, in order to avoid postoperative infections. The purpose of this work is to highlight the antimicrobial properties of the Artemisia absinthium essential oil-hydroxyapatite composites obtained by a simple method and at low costs. The structural properties and antimicrobial efficiency of the Artemisia absinthium essential oil-hydroxyapatite composite have been studied. The samples based on Artemisia absinthium essential oil analyzed in this study showed that wormwood essential oil presented the highest efficacy against the fungal strain of C. parapsilosis. It has been shown that wormwood essential oil has a strong antimicrobial effect against the microbial strains tested in this study. Furthermore, the antimicrobial properties of the biocomposites based on hydroxyapatite and essential oil are due to the presence of the essential oil in the samples.

Keywords: Arthemisia absinthium; antimicrobial properties; hydroxyapatite.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1

SEM images of HAp nanoparticles (a); 3D surface plot of SEM images of HAp (b); SEM images of HApWW sample (c); 3D surface plot of SEM images of HApWW sample (d) and AFM 2D and 3D surface topographies of HAp pellet (e,f) and HApWW pellet (g,h).

Figure 2

TEM image of HAp (a) and HApWW (c) nanoparticles. Distribution of HAp (b) and HApWW (d) nanoparticles obtained from TEM images.

Figure 3

Dynamic light scattering (DLS) measurements of size dispersion of HAp (black) and HApWW (red) represent data weighted by number (a) and volume (b) of particles.

Figure 4

The nitrogen adsorption/desorption isotherms of HAp (a) and HApWW (b) samples.

Figure 5

FTIR spectra of the HAp solution (a), WW EO (b) and HApWW (c) samples.

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