Strain identification of Mycobacterium tuberculosis by DNA fingerprinting: recommendations for a standardized methodology - PubMed (original) (raw)
Strain identification of Mycobacterium tuberculosis by DNA fingerprinting: recommendations for a standardized methodology
J D van Embden et al. J Clin Microbiol. 1993 Feb.
Abstract
DNA fingerprinting of Mycobacterium tuberculosis has been shown to be a powerful epidemiologic tool. We propose a standardized technique which exploits variability in both the number and genomic position of IS6110 to generate strain-specific patterns. General use of this technique will permit comparison of results between different laboratories. Such comparisons will facilitate investigations into the international transmission of tuberculosis and may identify specific strains with unique properties such as high infectivity, virulence, or drug resistance.
Comment in
- Characterization of Mycobacterium bovis BCG vaccines by DNA fingerprinting by a standardized methodology.
Arya SC. Arya SC. J Clin Microbiol. 1993 Oct;31(10):2834-5. doi: 10.1128/jcm.31.10.2834-2835.1993. J Clin Microbiol. 1993. PMID: 8110264 Free PMC article. No abstract available. - Usefulness of DNA fingerprinting in combating tuberculosis.
Allerberger F, Vogetseder W, Eille M, Dierich M. Allerberger F, et al. J Clin Microbiol. 1993 Jul;31(7):1959. doi: 10.1128/jcm.31.7.1959-.1993. J Clin Microbiol. 1993. PMID: 8349784 Free PMC article. No abstract available. - Implications of low frequency of IS6110 in fingerprinting field isolates of Mycobacterium tuberculosis from Kerala, India.
Radhakrishnan I, K MY, Kumar RA, Mundayoor S. Radhakrishnan I, et al. J Clin Microbiol. 2001 Apr;39(4):1683. doi: 10.1128/JCM.39.4.1683.2001. J Clin Microbiol. 2001. PMID: 11354035 Free PMC article. No abstract available.
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