Apolipoprotein C3 (-455T>C) polymorphism confers susceptibility to nonalcoholic fatty liver disease in the Southern Han Chinese population (original) (raw)
Prospective Study
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World J Gastroenterol. Oct 14, 2014; 20(38): 14010-14017
Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.14010
Table 4 Correlation between Apolipoprotein C3 (-455T>C) polymorphism and hypertension, dyslipidemia in the nonalcoholic fatty liver disease group n (%)
| Genotype | Metabolic component | P value | Adjusted OR (95%CI) | |
|---|---|---|---|---|
| Non-hypertension | Hypertension | |||
| TT | 82 (34.7) | 12 (18.8) | - | 1 |
| TC | 102 (43.2) | 29 (45.3) | 0.041 | 2.16 (1.02-4.57)1 |
| CC | 52 (22.1) | 23 (35.9) | 0.0032 | 3.42 (1.53-7.60)2 |
| Non-hypertriglyceridemia | Hypertriglyceridemia | |||
| TT | 71 (39.3) | 23 (19.3) | - | 1 |
| TC | 77 (42.5) | 54 (45.4) | 0.021 | 2.03 (1.12-3.68)1 |
| CC | 33 (18.2) | 42 (35.3) | < 0.0012 | 3.80 (1.95-7.41)2 |
| Normal HDL | Low HDL | |||
| TT | 63 (36.6) | 31 (24.2) | - | 1 |
| TC | 75 (43.6) | 56 (43.8) | 0.301 | 1.36 (0.76 -2.42)1 |
| CC | 34 (19.8) | 41 (32.0) | 0.012 | 2.34 (1.21 -4.52)2 |
| Non-hypercholesterolemia | Hypercholesterolemia | |||
| TT | 57 (32.0) | 37 (30.3) | - | 1 |
| TC | 81 (45.5) | 50 (41.0) | 0.521 | - |
| CC | 40 (22.5) | 35 (28.7) | 0.202 | - |
| Normal LDL | Increased LDL | |||
| TT | 65 (31.0) | 29 (32.2) | - | 1 |
| TC | 89 (42.3) | 42 (46.7) | 0.411 | - |
| CC | 56 (26.7) | 19 (21.1) | 0.332 | - |
- Citation: Li MR, Zhang SH, Chao K, Liao XH, Yao JY, Chen MH, Zhong BH. Apolipoprotein C3 (-455T>C) polymorphism confers susceptibility to nonalcoholic fatty liver disease in the Southern Han Chinese population. World J Gastroenterol 2014; 20(38): 14010-14017
- URL: https://www.wjgnet.com/1007-9327/full/v20/i38/14010.htm
- DOI: https://dx.doi.org/10.3748/wjg.v20.i38.14010