Consumption of garlic and risk of colorectal cancer: An updated meta-analysis of prospective studies (original) (raw)

Meta-Analysis

Copyright ©2014 Baishideng Publishing Group Inc. All rights reserved.

World J Gastroenterol. Nov 7, 2014; 20(41): 15413-15422
Published online Nov 7, 2014. doi: 10.3748/wjg.v20.i41.15413

Table 2 Subgroup analyses of garlic consumption and risk of colorectal cancer

Subgroup RC garlic intake Garlic supplement intake
No. of studies1 Relative risk (95%CI) Q-test I2 (%) Egger’s test No. of studies Relative risk (95%CI) Q-test I2 (%) Egger’s test
Colorectal cancer 4 1.07 (0.95-1.19) 0.66 0.0 0.50 5 1.12 (0.96-1.31) 0.11 46.9 0.61
Male 2 1.18 (0.99-1.41) 0.28 15.7 NA 3 1.24 (0.96-1.59) 0.31 13.6 0.75
Female 3 1.04 (0.80-1.34) 0.07 62.1 0.55 3 0.85 (0.64-1.11) 0.39 0.0 0.95
Colon cancer 4 1.07 (0.94-1.21) 0.63 0.0 0.23 3 1.01 (0.77-1.32) 0.15 47.3 0.58
Male 2 1.18 (0.98-1.43) 0.61 0.0 NA 2 1.30 (0.91-1.85) 0.39 0.0 NA
Female 3 1.01 (0.86-1.19) 0.10 56.5 0.49 2 0.73 (0.50-1.09) 0.85 0.0 NA
Rectal cancer 3 1.02 (0.90-1.17) 0.93 0.0 0.59 3 1.17 (0.74-1.83) 0.41 0.0 0.31
Male 2 1.13 (0.86-1.49) 0.26 22.5 NA 2 1.59 (0.94-2.69) 0.85 0.0 NA
Female 2 0.97 (0.67-1.40) 0.46 0.0 NA 2 0.69 (0.32-1.48) 1.00 0.0 NA
Proximal colon cancer 3 1.06 (0.88-1.28) 0.53 0.0 0.04 2 0.78 (0.51-1.21) 0.77 0.0 NA
Distal colon cancer 3 1.12 (0.87-1.45) 0.55 0.0 0.89 2 1.15 (0.43-3.12) 0.04 75.4 NA