Progress of mesenchymal stem cell therapy for neural and retinal diseases (original) (raw)

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World J Stem Cells. Apr 26, 2014; 6(2): 111-119
Published online Apr 26, 2014. doi: 10.4252/wjsc.v6.i2.111

Table 1 Registered clinical trials on mesenchymal stem cells for neural diseases

Identifier Country Status Study Phase of trial Estimated number of patients Estimated trial end Disease
NCT01377870 Iran Recruiting Evaluation of autologous mesenchymal stem cell transplantation (effects and side effects) in multiple sclerosis Phase 1/2 30 2013 Multiple sclerosis
NCT01895439 Jordan Recruiting Safety and efficacy study of autologous bone marrow mesenchymal stem cells in multiple sclerosis Phase 1/2 30 2014 Multiple sclerosis
NCT01883661 India Not yet recruiting Safety and efficacy of MSCs in MS Phase 1/2 15 2015 Multiple sclerosis
NCT00395200 United Kingdom Completed MSCIMS Phase 1/2 10 2010 Multiple sclerosis
NCT01854957 Italy Recruiting MESEMS Phase 1/2 20 2014 Multiple sclerosis
NCT01730547 Sweden Recruiting Mesenchymal stem cells for multiple sclerosis Phase 1/2 15 2015 Multiple sclerosis
NCT01364246 China Recruiting Safety and efficacy of umbilical cord mesenchymal stem cell therapy for patients with progressive multiple sclerosis and neuromyelitis optica Phase 1/2 20 2014 Multiple sclerosis
NCT01056471 Spain Unknown Autologous mesenchymal stem cells from adipose tissue in patients with secondary progressive multiple sclerosis (CMM/EM/2008) Phase 1/2 30 2012 Multiple sclerosis
NCT01228266 Spain Active, not recruiting Mesenchymal stem cell transplantation in MS (CMM-EM) Phase 2 16 2013 Multiple sclerosis
NCT00813969 United States Active, not recruiting Autologous MSC transplantation in MS Phase 1 24 2014 Multiple sclerosis
NCT01933802 United States Not yet recruiting Intrathecal administration of autologous MSC-NP in patients with multiple sclerosis Phase 1 20 2016 Multiple sclerosis
NCT01606215 United Kingdom Recruiting STREAMS Phase 1/2 13 2015 Multiple sclerosis
NCT01745783 Spain Recruiting Mesenchymal cells from autologous bone marrow, administered intravenously in patients diagnosed with multiple sclerosis Phase 1/2 30 2014 Multiple sclerosis
NCT00781872 Israel Unknown MSCs for the treatment of MS Phase 1/2 20 2009 Multiple sclerosis
NCT01694927 Chile Enrolling by invitation Autologous mesenchymal stem cells in spinal cord injury (SCI) patients (MSC-SCI) Phase 2 30 2014 Spinal cord injury
NCT01446640 China Recruiting Mesenchymal stem cells transplantation to patients with spinal cord injury (MSC) Phase 1/2 20 2014 Spinal cord injury
NCT01676441 South Korea Recruiting Safety and efficacy of autologous mesenchymal stem cells in chronic spinal cord injury Phase 2/3 32 2014 Spinal cord injury
NCT01769872 South Korea Recruiting Safety and effect of adipose tissue derived mesenchymal stem cell implantation in patients with spinal cord injury Phase 1/2 15 2014 Spinal cord injury
NCT01162915 United States Active, not recruiting Transfer of bone marrow derived stem cells for the treatment of spinal cord injury Phase 1 10 2013 Spinal cord injury
NCT01274975 South Korea Completed Autologous adipose derived mscs transplantation in patient with spinal cord injury Phase 1 8 2010 Spinal cord injury
NCT01624779 South Korea Recruiting Intrathecal transplantation of autologous adipose tissue derived msc in the patients with spinal cord injury Phase 1 15 2013 Spinal cord injury
NCT01393977 China Unknown Difference between rehabilitation therapy and stem cells transplantation in patients with spinal cord injury in China Phase 2 60 2012 Spinal cord injury
NCT01873547 China Recruiting Different efficacy between rehabilitation therapy and stem cells transplantation in patients with SCI in China (SCI-III) Phase 3 300 2014 Spinal cord injury
NCT01325103 Brazil Unknown Autologous bone marrow stem cell transplantation in patients with spinal cord injury Phase 1 20 2013 Spinal cord injury
NCT00816803 Egypt Completed Cell transplant in spinal cord injury patients Phase 1/2 80 2008 Spinal cord injury
NCT01343511 China Completed Safety and efficacy of stem cell therapy in patients with autism Phase 1/2 37 2011 Autism