doi:10.1038/clpt.2010.233>). A higher event rate translates to a lower sample size for the clinical trial, which can have both practical and ethical advantages. This package is a tool to help evaluate biomarkers for prognostic enrichment of clinical trials.">

BioPET: Biomarker Prognostic Enrichment Tool (original) (raw)

Prognostic Enrichment is a clinical trial strategy of evaluating an intervention in a patient population with a higher rate of the unwanted event than the broader patient population (R. Temple (2010) <doi:10.1038/clpt.2010.233>). A higher event rate translates to a lower sample size for the clinical trial, which can have both practical and ethical advantages. This package is a tool to help evaluate biomarkers for prognostic enrichment of clinical trials.

Version: 0.2.2
Depends: R (≥ 3.4.0)
Imports: ggplot2, gridExtra, pROC, VGAM
Published: 2018-07-17
DOI: 10.32614/CRAN.package.BioPET
Author: Jeremy Roth [cre, aut], Kathleen F. Kerr [aut], Kehao Zhu [aut]
Maintainer: Jeremy Roth
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: no
CRAN checks: BioPET results

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