MLML2R: Maximum Likelihood Estimation of DNA Methylation and Hydroxymethylation Proportions (original) (raw)
Maximum likelihood estimates (MLE) of the proportions of 5-mC and 5-hmC in the DNA using information from BS-conversion, TAB-conversion, and oxBS-conversion methods. One can use information from all three methods or any combination of two of them. Estimates are based on Binomial model by Qu et al. (2013) <doi:10.1093/bioinformatics/btt459> and Kiihl et al. (2019) <doi:10.1515/sagmb-2018-0031>.
| Version: | 0.3.3 |
|---|---|
| Suggests: | minfi, microbenchmark, GEOquery, knitr, rmarkdown, IlluminaHumanMethylation450kmanifest |
| Published: | 2019-10-17 |
| DOI: | 10.32614/CRAN.package.MLML2R |
| Author: | Samara Kiihl [aut, cre], Maria Jose Martinez-Garrido [aut], Arce Domingo-Relloso [aut], Jose Bermudez [aut], Maria Tellez-Plaza [aut] |
| Maintainer: | Samara Kiihl |
| BugReports: | https://github.com/samarafk/MLML2R/issues |
| License: | MIT + file |
| URL: | https://github.com/samarafk/MLML2R |
| NeedsCompilation: | no |
| Citation: | MLML2R citation info |
| CRAN checks: | MLML2R results |
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