Phase12Compare: Simulates SPSO and Efftox Phase 12 Trials with Correlated Outcomes (original) (raw)
Simulating and conducting four phase 12 clinical trials with correlated binary bivariate outcomes described. Uses the 'Efftox' (efficacy and toxicity tradeoff, <https://biostatistics.mdanderson.org/SoftwareDownload/SingleSoftware/Index/2>) and SPSO (Semi-Parametric Stochastic Ordering) models with Utility and Desirability based objective functions for dose finding.
| Version: | 1.5 |
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| Imports: | Rcpp (≥ 0.12.18), mvtnorm |
| LinkingTo: | Rcpp, RcppArmadillo |
| Published: | 2020-07-31 |
| DOI: | 10.32614/CRAN.package.Phase12Compare |
| Author: | Andrew G Chapple |
| Maintainer: | Andrew G Chapple |
| License: | GPL-2 |
| NeedsCompilation: | yes |
| CRAN checks: | Phase12Compare results |
Documentation:
| Reference manual: | Phase12Compare.html , <Phase12Compare.pdf> |
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Downloads:
| Package source: | Phase12Compare_1.5.tar.gz |
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| Windows binaries: | r-devel: Phase12Compare_1.5.zip, r-release: Phase12Compare_1.5.zip, r-oldrel: Phase12Compare_1.5.zip |
| macOS binaries: | r-release (arm64): Phase12Compare_1.5.tgz, r-oldrel (arm64): Phase12Compare_1.5.tgz, r-release (x86_64): Phase12Compare_1.5.tgz, r-oldrel (x86_64): Phase12Compare_1.5.tgz |
| Old sources: | Phase12Compare archive |
Linking:
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