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basksim

Overview

basksim calculates the operating characteristics of different basket trial designs based on simulation.

Installation

Install the development veresion with:

Usage

With basksim you can calculate the operating characteristics such as rejection probabilities and mean squared error of single-stage basket trials with different designs.

At first, you have to create a design-object using a setup-function. For example to create a design-object for Fujikawa’s design (Fujikawa et al., 2020):

k is the number of baskets, shape1 and shape2 are the shape parameters of the Beta-prior of the response probabilities of each baskets and p0 is the response probability that defines the null hypothesis.

Use get_details to estimate several important operating characteristics: