catmap: Case-Control and TDT Meta-Analysis Package (original) (raw)

Although many software tools can perform meta-analyses on genetic case-control data, none of these apply to combined case-control and family-based (TDT) studies. This package conducts fixed-effects (with inverse variance weighting) and random-effects [DerSimonian and Laird (1986) <doi:10.1016/0197-2456(86)90046-2>] meta-analyses on combined genetic data. Specifically, this package implements a fixed-effects model [Kazeem and Farrall (2005) <doi:10.1046/j.1529-8817.2005.00156.x>] and a random-effects model [Nicodemus (2008) <doi:10.1186/1471-2105-9-130>] for combined studies.

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