combiroc: Selection and Ranking of Omics Biomarkers Combinations Made Easy (original) (raw)
Provides functions and a workflow to easily and powerfully calculating specificity, sensitivity and ROC curves of biomarkers combinations. Allows to rank and select multi-markers signatures as well as to find the best performing sub-signatures, now also from single-cell RNA-seq datasets. The method used was first published as a Shiny app and described in Mazzara et al. (2017) <doi:10.1038/srep45477> and further described in Bombaci & Rossi (2019) <doi:10.1007/978-1-4939-9164-8_16>, and widely expanded as a package as presented in the bioRxiv pre print Ferrari et al. <doi:10.1101/2022.01.17.476603>.
| Version: | 0.3.4 |
|---|---|
| Depends: | R (≥ 3.5.0) |
| Imports: | tidyr, dplyr, ggplot2, gtools, pROC, stringr, stats, utils, moments |
| Suggests: | testthat (≥ 3.0.0), knitr, markdown, rmarkdown, httr, Seurat |
| Published: | 2023-07-06 |
| DOI: | 10.32614/CRAN.package.combiroc |
| Author: | Ivan Ferrari |
| Maintainer: | Riccardo L. Rossi <ric.rossi at gmail.com> |
| BugReports: | https://github.com/ingmbioinfo/combiroc/issues |
| License: | MIT + file |
| URL: | https://doi.org/10.1101/2022.01.17.476603,https://github.com/ingmbioinfo/combiroc |
| NeedsCompilation: | no |
| Language: | en-US |
| Materials: | README, NEWS |
| CRAN checks: | combiroc results |
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