qpNCA: Noncompartmental Pharmacokinetic Analysis by qPharmetra (original) (raw)
Computes noncompartmental pharmacokinetic parameters for drug concentration profiles. For each profile, data imputations and adjustments are made as necessary and basic parameters are estimated. Supports single dose, multi-dose, and multi-subject data. Supports steady-state calculations and various routes of drug administration. See ?qpNCA and vignettes. Methodology follows Rowland and Tozer (2011, ISBN:978-0-683-07404-8), Gabrielsson and Weiner (1997, ISBN:978-91-9765-100-4), and Gibaldi and Perrier (1982, ISBN:978-0824710422).
| Version: | 1.1.6 |
|---|---|
| Depends: | R (≥ 3.3.0) |
| Imports: | dplyr (≥ 0.7.0), tidyr (≥ 0.8.2), magrittr, ggplot2, knitr |
| Suggests: | rmarkdown, markdown, covr, testthat (≥ 2.1.0) |
| Published: | 2021-08-16 |
| DOI: | 10.32614/CRAN.package.qpNCA |
| Author: | Jan Huisman [aut, cre], Koen Jolling [ctb], Krina Mehta [ctb], Tim Bergsma [ctb] |
| Maintainer: | Jan Huisman <jan.huisman at qpharmetra.com> |
| License: | GPL-3 |
| NeedsCompilation: | no |
| Materials: | README |
| In views: | MissingData, Pharmacokinetics |
| CRAN checks: | qpNCA results |
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