doi:10.1007/978-3-319-32562-0>. This includes classical group sequential as well as multi-stage adaptive hypotheses tests that are based on the combination testing principle.">

rpact: Confirmatory Adaptive Clinical Trial Design and Analysis (original) (raw)

Design and analysis of confirmatory adaptive clinical trials with continuous, binary, and survival endpoints according to the methods described in the monograph by Wassmer and Brannath (2016) <doi:10.1007/978-3-319-32562-0>. This includes classical group sequential as well as multi-stage adaptive hypotheses tests that are based on the combination testing principle.

Version: 4.2.1
Depends: R (≥ 3.6.0)
Imports: methods, stats, utils, graphics, tools, rlang, R6 (≥ 2.5.1), knitr (≥ 1.19), Rcpp (≥ 1.0.3)
LinkingTo: Rcpp
Suggests: ggplot2 (≥ 3.5.0), testthat (≥ 3.0.0), rmarkdown (≥ 1.10), rappdirs (≥ 0.3.3)
Published: 2025-07-24
DOI: 10.32614/CRAN.package.rpact
Author: Gernot Wassmer ORCID iD [aut], Friedrich Pahlke ORCID iD [aut, cre], Till Jensen [ctb], Daniel Sabanes BoveORCID iD [ctb], Stephen SchueuerhuisORCID iD [ctb], Tobias Muetze ORCID iD [ctb]
Maintainer: Friedrich Pahlke <friedrich.pahlke at rpact.com>
BugReports: https://github.com/rpact-com/rpact/issues
License: LGPL-3
URL: https://www.rpact.org, https://www.rpact.com,https://github.com/rpact-com/rpact,https://rpact-com.github.io/rpact/,https://rpact.shinyapps.io/connect
NeedsCompilation: yes
Language: en-US
Citation: rpact citation info
Materials: README, NEWS
In views: ClinicalTrials
CRAN checks: rpact results

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