ubiquity: PKPD, PBPK, and Systems Pharmacology Modeling Tools (original) (raw)

Complete work flow for the analysis of pharmacokinetic pharmacodynamic (PKPD), physiologically-based pharmacokinetic (PBPK) and systems pharmacology models including: creation of ordinary differential equation-based models, pooled parameter estimation, individual/population based simulations, rule-based simulations for clinical trial design and modeling assays, deployment with a customizable 'Shiny' app, and non-compartmental analysis. System-specific analysis templates can be generated and each element includes integrated reporting with 'PowerPoint' and 'Word'.

Version:	2.0.3
Depends:	R (≥ 3.5.0)
Imports:	cli, deSolve, dplyr (≥ 1.0.0), digest, doParallel, flextable, foreach, ggplot2, knitr, magrittr, MASS, onbrand (≥ 1.0.2), optimx, PKNCA, pso, readxl, rmarkdown, rhandsontable, scales, stats, stringr, shiny
Suggests:	GA, GGally, gridGraphics, gridExtra, grid, officer, webshot, ggrepel, rstudioapi, testthat
Published:	2024-03-08
DOI:	10.32614/CRAN.package.ubiquity
Author:	John Harrold [aut, cre]
Maintainer:	John Harrold <john.m.harrold at gmail.com>
BugReports:	https://github.com/john-harrold/ubiquity/issues
License:	BSD_2_clause + file
URL:	https://ubiquity.tools/rworkflow
NeedsCompilation:	no
SystemRequirements:	Perl
Citation:	ubiquity citation info
Materials:	README NEWS
In views:	Pharmacokinetics
CRAN checks:	ubiquity results

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