sahil rasane - Academia.edu (original) (raw)

Papers by sahil rasane

Indian journal of respiratory care, Oct 29, 2023

Saudi Journal of Medicine and Medical Sciences, 2016

RP is characterized by widespread, inflammatory, destructive, and degenerative lesions. No labora... more RP is characterized by widespread, inflammatory, destructive, and degenerative lesions. No laboratory test is pathognomonic for this disease. Disease manifestations vary with the severity and depend on organ involvement. Apart from fever, the common myalgia manifestations include auricular chondritis (60-100%); nonerosive non inflammatory arthritis, mostly proximal interphalangeal joints (50-80%); episcleritis and scleritis (50-60%); nasal chondritis (50%); and laryngotracheal involvement (20%). Other organ involvement includes cardiac (valvular lesions and arrhythmias), renal, dermatological, and neurological manifestations. As no laboratory test is pathognomic for RP, diagnosis is based on Damiani and Levine modification of McAdam's criteria. [3] Treatment depends on the severity of the illness with mild disease managed by NSAIDS. Severe illness may require steroids, immunosuppressants like cyclophosphamide, azathioprine, cyclosporine, and methotrexate. Biological agents are found to be useful in those patients who are difficult to treat.

Indian journal of respiratory care, Oct 29, 2023

Saudi Journal of Medicine and Medical Sciences, 2016

RP is characterized by widespread, inflammatory, destructive, and degenerative lesions. No labora... more RP is characterized by widespread, inflammatory, destructive, and degenerative lesions. No laboratory test is pathognomonic for this disease. Disease manifestations vary with the severity and depend on organ involvement. Apart from fever, the common myalgia manifestations include auricular chondritis (60-100%); nonerosive non inflammatory arthritis, mostly proximal interphalangeal joints (50-80%); episcleritis and scleritis (50-60%); nasal chondritis (50%); and laryngotracheal involvement (20%). Other organ involvement includes cardiac (valvular lesions and arrhythmias), renal, dermatological, and neurological manifestations. As no laboratory test is pathognomic for RP, diagnosis is based on Damiani and Levine modification of McAdam's criteria. [3] Treatment depends on the severity of the illness with mild disease managed by NSAIDS. Severe illness may require steroids, immunosuppressants like cyclophosphamide, azathioprine, cyclosporine, and methotrexate. Biological agents are found to be useful in those patients who are difficult to treat.