Elif Eroglu | Acibadem University (original) (raw)

Papers by Elif Eroglu

European Journal of Echocardiography, 2006

Background: Purpose of this study was to determine the clinical feasibility and reproducibility o... more Background: Purpose of this study was to determine the clinical feasibility and reproducibility of Tissue Doppler echocardiography with strain rate imaging (TDE/SRI) at rest and under physical exercise in healthy young individuals. Material and methods: Forty-five healthy young persons (age 9-29 years) underwent echocardiography with TDE/SRI at rest and during a bicycle exercise test (2 W/kg body weight for 5 minutes). Systolic (Vs) and early diastolic (Ve) velocities, systolic strain rate (SRs) and strain (S) were calculated as peak values in each segment of 2-and 4-chamber views (LV longitudinal) and of parasternal long-and short axis views (LV radial). Longitudinal function of free right ventricular wall (RV longitudinal) was determined on 4-chamber views. Because no base-to-apex gradient was present, mean values for longitudinal strain and strain rate were computed for LV and RV, while systolic and early diastolic velocities were given for each ventricle as peak values from basal segments. Results: Results are displayed in . Variability of observations is shown in . Conclusions: 1. Tissue Doppler with strain rate imaging is a practical and robust method for assessment of regional longitudinal function of both ventricles and of local radial LV function at rest and under exercise. 2. Local myocardial relaxation (Ve) and contractility (SRs) increased significantly under physical exercise. These normal values obtained from healthy young subjects can serve as a reference database for further clinical studies. by guest on January 2, 2012 http://ejechocard.oxfordjournals.org/ Downloaded from S4 Abstracts Eur J Echocardiography Abstracts Supplement, December 2006

Türk Kardiyoloji Derneği arşivi : Türk Kardiyoloji Derneğinin yayın organıdır, 2008

Traditional risk factors may underestimate the burden of subclinical atherosclerosis in women. Re... more Traditional risk factors may underestimate the burden of subclinical atherosclerosis in women. Recently, multislice computed tomography (MSCT) has become widely available in detecting early coronary artery disease (CAD). We sought the prevalence of CAD in low to moderate-risk asymptomatic women by MSCT coronary artery calcium (CAC) scoring and coronary angiography. The study included 185 women (mean age 57+/-12 years) without known CAD and diabetes, with low or moderate risk for CAD based on traditional risk scoring. Coronary artery calcium scoring and coronary angiography were performed by MSCT, which included a segment-based plaque detection and characterization of calcification. The plaques were classified based on the luminal stenotic effect (>50%). Patients with = or >1 stenotic plaque were classified as having obstructive CAD. Angiographic findings were compared with calcium scores. Coronary artery calcium scoring and coronary angiography detected CAD in 63 (34.1%) and 1...

Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2008

The evaluation of left ventricular function and viability is critical in patients with suspected ... more The evaluation of left ventricular function and viability is critical in patients with suspected or documented ischemic heart disease. Recently, cardiac multislice computed tomography (MSCT) has emerged as a powerful modality for cardiac imaging. In addition to coronary artery assessment, contrast enhanced MSCT can provide reliable information about myocardial function, perfusion and viability. This review will focus on the pathophysiological mechanisms and clinical applications of contrast enhanced myocardial function and viability MSCT imaging.

European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology, 2005

The aim of this study was to investigate the clinical applicability of strain and strain rate ima... more The aim of this study was to investigate the clinical applicability of strain and strain rate imaging (epsilon/SRI) in heart transplantation (Htx) patients and to establish "normal" post-Htx regional systolic deformation values. Epsilon/SR indices have been shown to be a more sensitive measure of regional systolic function than standard echo measurements. Thus, they might provide a new tool to better define both normal cardiac graft function and detect changes due to post-Htx complications. However, prior to investigating the role of epsilon/SRI in detecting abnormalities, "normal" post-Htx regional deformation values must be established as graft regional function can be altered by a number of factors such as ischemic time, surgical technique or accelerated graft ageing. A total of 57 Htx patients (age 36+/-12 years; post-Htx 5.5+/-3 years) without any documented complication were studied. Epsilon/SRI data were acquired from the septum, left ventricular (LV) free...

Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2004

Atherosclerosis Supplements, 2008

Abstracts p<0.001 and CO, 61614-1771 vs. 5618+.9335 cm3/min, p<0.01). MPI increased significantly... more Abstracts p<0.001 and CO, 61614-1771 vs. 5618+.9335 cm3/min, p<0.01). MPI increased significantly afler HD (0.3754-0.161 at baselinevs. 0.4834-0.258 after HD, p<0.05). This was a resull el a decrease in EjT noted alter p<0.0001), IVRT and IVCT did not change after HD in comparison with baseline. Conclusion: Preload reduction by haemodialysis has an influence on systolic and diastolic lunctions as well as on myocardial performance index. MPI is slrongly preload dependent.

Since the left atrial (LA) size has been recognized as a critical determinant in a variety of car... more Since the left atrial (LA) size has been recognized as a critical determinant in a variety of cardiac diseases that show the ventricular diastolic dysfunction, more accurate measurement of LA volume is required in the clinical settings. In this study we tested feasibility and reliability of a new, real-time triplane 3DE to measure LA volume and compared the measures to those from 2DE, which present the current standard. Methods: To test the volumetric reliability of 3DE (Vivid7 Dimension, G E Yokogawa Medical) in vitro, 11 water-filled (36 to 320ml) latex balloon phantoms with various shapes were used. For in vivo study, we studied 52 patients by 2DE and real-time triplane 3DE. LA volume by 3DE was calculated from the geometric method, using simultaneously collected equally spaced 3 tomograms (by increments of 60 degrees) from the apical window. LA volume by 2DE was calculated by the modified single-plane (4-chamber and 2-chamber) and bi-plane Simpson's rule. In addition, LA antero-posterior dimension (LAD) was measured by 2DE. Results: In vitro study, there was a high correlation and good agreement (y=1.0x-3.3(ml), r=0.99, p<0.0001) between the true volume and the estimated volume by 3DE. In patients, LA volume by 3DE ranged from 36 to 199 mL (79±35 mL). These 3DE measures were tightly correlated to any types of LA measures by 2DE. However there were consistent underestimations by 2DE-derived data (biplane: y=0.72x + 13.0, r=0.88, bias=-13.7 mL, single-4 chamber: y=0.68x + 14.1, r=0.81, bias=-16.3 mL, single-2 chamber: y=0.77x + 13.2, r=0.85, bias=-14.3 mL). Besides, while LAD had a statistically significant correlation with 3DE-derived volume, the correlation was not satisfactory (y=0.016x+2.5, r=0.79).

The averaged_standard deviation of the end-systolic SR, SL and SC of ASW and ISW are given in and... more The averaged_standard deviation of the end-systolic SR, SL and SC of ASW and ISW are given in and mean curves from LAx in .

Journal of Cardiovascular Medicine, 2008

We present an image of giant fistula between severely enlarged right coronary artery and coronary... more We present an image of giant fistula between severely enlarged right coronary artery and coronary sinus, which was evaluated by echocardiography, conventional coronary angiography and multislice computed tomography coronary angiography.

IEEE Ultrasonics Symposium, 2005., 2005

In this paper, the concept of principal component analysis for the quantitative assessment of seg... more In this paper, the concept of principal component analysis for the quantitative assessment of segmental myocardial deformation characteristics is explored. Hereto, a statistical model including the variations in deformation properties among 80 healthy individuals was built. This model was subsequently used to detect abnormal deformation traces. (Abstract)

Background: There has been a continued search for a more sensitive noninvasive technique for dete... more Background: There has been a continued search for a more sensitive noninvasive technique for detecting sub-clinical acute rejection in heart transplant recipients.

Cardiology in the Young, 2014

Acute type A aortic dissection is a catastrophic situation, often accompanied by aortic regurgita... more Acute type A aortic dissection is a catastrophic situation, often accompanied by aortic regurgitation. A rarely described cause of aortic regurgitation, in this clinical scenario, is the prolapse of an intimal flap into the left ventricular outflow tract. We present here a case of acute type A aortic dissection with a circumferential intimal flap, prolapsing into the left ventricular outflow tract and causing massive aortic regurgitation.

European …, 2005

curring in 30% and 75% ol patients, respectively) allowed to identily patients with significantly... more curring in 30% and 75% ol patients, respectively) allowed to identily patients with significantly higher risk of death than patients with negative ESE (15.1% vs. 3.3%, p<0.0001, and 21.3% vs. 9.6%, p<O.0001 -respectively). Conclusions: Exercise stress echo yields prognostic inlormation in known or suspected CAD, especially in patients with intermediate pretest level ol risk. The combined evaluation of clinical variables and other ESE variables, such as peak WMSI and exercise capacity, may further select patients at greatest risk ol cardiac death in the overall population.

The Thoracic and Cardiovascular Surgeon, 2013

The study evaluates the alterations in exercise capacity of chronic thromboembolic pulmonary hype... more The study evaluates the alterations in exercise capacity of chronic thromboembolic pulmonary hypertension (CTEPH) patients after pulmonary endarterectomy (PEA) and investigates the echocardiographic parameters associated with the degree of functional recovery. Thirty consecutive patients with the diagnosis of CTEPH (17 males; mean age, 45.9 ± 15.1 years) who had been referred for PEA operation were included in the study. Each patient underwent transthoracic echocardiography and 6-minute walk test (6-MWT) before and 6 months after PEA. After PEA, 6-MWT distances significantly increased (242.8 ± 112.8 m vs. 423.6 ± 89.1 m, p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.001), whereas systolic pulmonary artery pressures and right ventricular dimensions significantly decreased (86 ± 25.1 mm Hg vs. 41.9 ± 15.6 mm Hg, p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.001 and 42.1 ± 10.1 mm vs. 35.3 ± 5.6 mm, p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.001, respectively). Magnitude of change in 6-MWT distance (Δ-6-MWT) was found to be correlated with concomitant change in tricuspid annular plane systolic excursion and left ventricular myocardial performance index (r: 0.518, p: 0.004 and r: -0.385, p: 0.043, respectively). Linear regression analysis revealed preoperative 6-MWT distance as an independent negative predictor of delta-6-MWT (beta: -0.89, t: -3.97, p: 0.001). CTEPH patients with more severely depressed exercise capacity at baseline displayed relatively greater degree of functional recovery after PEA in our study. Improvement in functional capacity was found to be correlated with improvement in parameters reflecting right ventricular functions rather than improvement in pulmonary artery pressure after PEA operation.

Journal of the American Society of Echocardiography, 2003

We present a case of hypereosinophilic syndrome with a large apical mass, which markedly reduced ... more We present a case of hypereosinophilic syndrome with a large apical mass, which markedly reduced end-systolic left ventricular cavity volume. Standard blood pool Doppler findings showed a restrictive filling pattern. However, ultrasound-derived regional strain rate and strain parameters suggested that wall deformation was not compromised, inferring that the restrictive filling pattern in this case was solely as a result of the reduction in end-systolic cavity size.

Journal of the American College of Cardiology, 2004

Cardiac Function and Heart Failure (6.7% ) to infection. In 2 patients (13.3%) the cause of death... more Cardiac Function and Heart Failure (6.7% ) to infection. In 2 patients (13.3%) the cause of death was unknown. Of the 10 patients who died in connection with biopsy-proven AR, 6 also had relevant CAV that developed after the second post-HTx year. In 10 patients with moderate/severe late ARs, but without CAV during their first episode of late AR diagnosed at 4.6± 3.0 years after HTx, the angiogram showed relevant CAV lesions 2.4± 1.3 years after the first late AR. The mean number of late ARs/patient/year was higher in those with angiographic CAV that developed after the second post-HTx year than in those without CAV after >2 years since HTx (p<0.01). Conclusions: Late ARs are the major cause of late allograft dysfunction in children and may also be involved in the development of CAV. Together with CAV, late ARs are the dominant cause of death after the second post-HTx year and thus, continuous and close rejection surveillance late after HTx is justified to improve the long-term outcome.

The Journal of Rheumatology, 2010

Non-alcoholic fatty liver disease (NAFLD) has been considered as a benign disease often associate... more Non-alcoholic fatty liver disease (NAFLD) has been considered as a benign disease often associated with central obesity and insulin resistance and, in general, with factors of the metabolic syndrome. Heart rate recovery after exercise is a function of vagal reactivation, and its impairment is an independent prognostic indicator for cardiovascular and all-cause mortality. The aim of our study was to evaluate the heart rate recovery index in patients with NAFLD.

The International Journal of Cardiovascular Imaging, 2009

We have evaluated the prevalence of left main coronary artery disease (LMCAD) among patients refe... more We have evaluated the prevalence of left main coronary artery disease (LMCAD) among patients referred to multislice computed tomography (MSCT) coronary angiography examinations. The study Group comprised of 1,000 consecutive patients (750 male and 250 female; mean age 53±12 years) who underwent successful 64-slice MSCT examinations. Left main coronary artery (LMCA) was classified into three Groups: normal LMCA; nonsignificant LMCAD with coronary plaques resulting in obstructions B50%; and significant LMCAD corresponding to obstructions [50%. We have found that 24 patients (2.4%) had significant LMCAD. Additional 200 patients (20%) had nonsignificant LMCAD. Univariate analysis revealed that LMCAD was associated with age, male gender, diabetes, hypertension, hyperlipidemia, typical symptoms, history of previous myocardial infarction and previous percutaneous coronary intervention. Only age and male gender were found as independent predictors for LMCAD in multivariate analysis (P \ 0.001 and P = 0.001, respectively,). Angiographic follow-up was avaliable for the 24 patients with significant LMCAD, and conventional coronary angiography confirmed the presence of significant LMCAD in all of these patients. Significant LMCAD was found in 2.4% of the 1,000 patients referred to 64-slice MSCT examinations. Age and male gender were the independent predictors for LMCAD.