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Address: Cúcuta, Norte de Santander, Colombia

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Papers by sebastian rojas

Research paper thumbnail of IMPROVEMENT OF BIODISTRIBUTION IN CARDIAC STEM CELL THERAPY USING FIBRINOGEN

Journal of The American College of Cardiology, 2010

Background: Successful stem cell delivery and biodistribution are pivotal factors for effcient st... more Background: Successful stem cell delivery and biodistribution are pivotal factors for effcient stem cell therapy. We used fuorescent microsphere particles to simulate cell retention and biodistribution after cardiac regenerative therapy. Fibrinogen was evaluated to augment particle retention.

Research paper thumbnail of The case for active management from the perspective of Complexity Theory

This paper approaches active management of baskets of currencies from the perspective of Complexi... more This paper approaches active management of baskets of currencies from the perspective of Complexity theory, where the market is analysed as a Complex Adaptive system. A basket of currencies is constructed using objective probabilities (propensities) and an artificial intelligence optimization technique that allows for implicit learning of correlations dynamics. Statistical tests of the diversification benefit are presented.

Research paper thumbnail of The case for active management from the perspective of Complexity Theory

This paper approaches active management of baskets of currencies from the perspective of Complexi... more This paper approaches active management of baskets of currencies from the perspective of Complexity theory, where the market is analysed as a Complex Adaptive system. A basket of currencies is constructed using objective probabilities (propensities) and an artificial intelligence optimization technique that allows for implicit learning of correlations dynamics. Statistical tests of the diversification benefit are presented.

Research paper thumbnail of Microtubule-Associated Protein 1B Interaction with Tubulin Tyrosine Ligase Contributes to the Control of Microtubule Tyrosination

Developmental Neuroscience, 2008

duced proportion of tyrosinated microtubules, we analyzed the possible interaction between MAP1B ... more duced proportion of tyrosinated microtubules, we analyzed the possible interaction between MAP1B and tubulin tyrosine ligase. Our results show that these proteins indeed interact and that the interaction is not affected by MAP1B phosphorylation. Additionally, neurons lacking MAP1B, when exposed to drugs that reversibly depolymerize microtubules, do not fully recover tyrosinated microtubules upon drug removal. These results suggest that MAP1B regulates tyrosination of ␣ -tubulin in neuronal microtubules. This regulation may be important for general processes involved in nervous system development such as axonal guidance and neuronal migration.

Research paper thumbnail of IMPROVEMENT OF BIODISTRIBUTION IN CARDIAC STEM CELL THERAPY USING FIBRINOGEN

Journal of The American College of Cardiology, 2010

Background: Successful stem cell delivery and biodistribution are pivotal factors for effcient st... more Background: Successful stem cell delivery and biodistribution are pivotal factors for effcient stem cell therapy. We used fuorescent microsphere particles to simulate cell retention and biodistribution after cardiac regenerative therapy. Fibrinogen was evaluated to augment particle retention.

Research paper thumbnail of The case for active management from the perspective of Complexity Theory

This paper approaches active management of baskets of currencies from the perspective of Complexi... more This paper approaches active management of baskets of currencies from the perspective of Complexity theory, where the market is analysed as a Complex Adaptive system. A basket of currencies is constructed using objective probabilities (propensities) and an artificial intelligence optimization technique that allows for implicit learning of correlations dynamics. Statistical tests of the diversification benefit are presented.

Research paper thumbnail of The case for active management from the perspective of Complexity Theory

This paper approaches active management of baskets of currencies from the perspective of Complexi... more This paper approaches active management of baskets of currencies from the perspective of Complexity theory, where the market is analysed as a Complex Adaptive system. A basket of currencies is constructed using objective probabilities (propensities) and an artificial intelligence optimization technique that allows for implicit learning of correlations dynamics. Statistical tests of the diversification benefit are presented.

Research paper thumbnail of Microtubule-Associated Protein 1B Interaction with Tubulin Tyrosine Ligase Contributes to the Control of Microtubule Tyrosination

Developmental Neuroscience, 2008

duced proportion of tyrosinated microtubules, we analyzed the possible interaction between MAP1B ... more duced proportion of tyrosinated microtubules, we analyzed the possible interaction between MAP1B and tubulin tyrosine ligase. Our results show that these proteins indeed interact and that the interaction is not affected by MAP1B phosphorylation. Additionally, neurons lacking MAP1B, when exposed to drugs that reversibly depolymerize microtubules, do not fully recover tyrosinated microtubules upon drug removal. These results suggest that MAP1B regulates tyrosination of ␣ -tubulin in neuronal microtubules. This regulation may be important for general processes involved in nervous system development such as axonal guidance and neuronal migration.

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