Dr. P J Parameaswari | Ministry of Health (original) (raw)

Papers by Dr. P J Parameaswari

Research paper thumbnail of ISSN 2347-954X (Print) Stress among Women in Sub-Urban area of South Chennai, India

Abstract: The aim of this study was to estimate the Prevalence of stress among 200 women of repro... more Abstract: The aim of this study was to estimate the Prevalence of stress among 200 women of reproductive age. It"s a Cross Sectional Study in Sub-Urban Chennai with information"s on demographic and stress collected by personal interview method using a structured questionnaire from women of age (18-45) years after obtaining the written informed consent. The important findings are Prevalence was 69.5% and Women with younger Age <30 and BMI <25 were found to be at major risk of stress with statistical significance. The prevalence of STRESS in south Chennai women is slightly lesser than those found in earlier studies. We suggest that the "Stressed Women at Risk group for Illness" should be identified from the community at the earlier age for health assistance to lead a better quality of life.

Research paper thumbnail of Tool Development in Health Care Research

Measures of Population Health would need to be compatible across nation and cultures to serve as ... more Measures of Population Health would need to be compatible across nation and cultures to serve as measures for making global health policy. Health state valuations on the basis of utility instruments such as rating scales, ex. the Visual Analog Scale or methods such as personal trade-off, time trade-off and standard gamble are one of the critical inputs that contribute to the calculation of summary measures of population health. These methods are supposed to assess an individual's valuation of hypothetical health states in terms of a single number indicating the value placed on a health state relative to perfect health or death.

Research paper thumbnail of Testing of Defects per Million Medication Orders as a SMART Indicator for Monitoring Medication Safety in Admission and Discharge Orders

Global Journal on Quality and Safety in Healthcare, 2021

Introduction The study investigated the use of defects per million medication orders (DPMMO) as a... more Introduction The study investigated the use of defects per million medication orders (DPMMO) as a SMART (specific, measurable, achievable, realistic, and timely) indicator for monitoring medication safety in admission and discharge orders. The study aimed to develop and test a new indicator as an investigator of medication safety. Methods The study was conducted in 2018 at King Saud Medical City in Riyadh City in Saudi Arabia. A retrospective cross-sectional design was used. The research sample had 292 patients. The selected medication orders included two types of medication orders (admission and discharge order). After sufficient data had been gathered from the hospitals, a statistical analysis was carried out. Results Analysis of admission and discharge orders indicated that defects per million opportunities (DPMO) and DPMMO count were slightly low, while the sigma level for admission orders was slightly high. Thus, the admission order process was slightly better than the discharg...

Research paper thumbnail of Pressure Injury Prevalence and Risk Factors among Adult Critically Ill Patients at a Large Intensive Care Unit

Purpose: To know the pressure injuries prevalence, locations, and stages in the intensive care un... more Purpose: To know the pressure injuries prevalence, locations, and stages in the intensive care unit and its associated factors. Design: Cross-sectional study. Method: Prevalence study was conducted over six months, from December 2015 to May 2016. Findings: Prevalence of pressure injury was 35.7% (154 patients out of 431 had at least one pressure injury), this is excluding stage one pressure injuries and the medical device related pressure injuries. The sacrum was the most frequent location of PIs followed by trochanter, ear, heel, buttocks, and ankle. Stage two pressure injuries was the most commonly observed among critically ill patients. We found a significant association between the pressure injuries and the age of patient, Body mass index, and Length of stay. Conclusion: Measuring prevalence of pressure injuries among critically ill patients is crucial and should be highlighted for all critical care sittings.

Research paper thumbnail of Delirium Incidence and Risk Factors in Adult Critically Ill Patients in Saudi Arabia

Background: Delirium in intensive care units (ICUs) is associated with long ICU stay, long hospit... more Background: Delirium in intensive care units (ICUs) is associated with long ICU stay, long hospital stay and increased costs of treatment. Unfortunately, delirium in ICU is significantly underestimated and overlooked by healthcare providers. Aims: The aim of this tudy is to determine the incidence and associated risk factors of delirium among critically ill patients in Saudi Arabia. Methods: This is a prospective study. Patients were assessed for delirium using the confusion assessment method for the ICU. Delirium was the independent variable in this study. Results: Fifty-nine patients (17.3%) showed positive delirium at least once compared to 283 patients (82.7%) who did not show positive delirium. Certain factors for delirium found to be significantly correlated with delirium (P < 0.005); including receiving sedation, mode of sedation, receiving mechanical ventilation, resistance to mechanical ventilator, and baseline Glasgow Coma Scale. Conclusion: Delirium occurred in >17%...

Research paper thumbnail of Radiographic evaluation of bone density in dentulous and edentulous patients in Riyadh, KSA

Nigerian Journal of Clinical Practice, 2020

Background: The Cone Beam Computed Tomography (CBCT) is currently being used as the most common d... more Background: The Cone Beam Computed Tomography (CBCT) is currently being used as the most common diagnostic method to evaluate the bone density of the maxilla and the mandible for planning dental implant. Aim: The aim of the study is to check the quantitative alveolar bone density in complete or partial edentulous and dentulous male and female patients among Riyadh sample population in Saudi Arabia. Materials and Methods: The study involved a cross-sectional analysis of 231 consecutive CBCT images of 231 different patients (115 males and 116 females). The scans were of Saudi National patients who were partially or completely edentulous without any bone infections in the maxilla and the mandible. The findings are presented as descriptive statistics and inferential statistics: student -t-test for two group means, ANOVA for three groups, Post-hoc LSD test for multiple comparisons, Levene statistics for testing the homogeneity of variances and a statistical significance at 5% level. Resu...

Research paper thumbnail of Serum 25(OH)D and type 2 Diabetes mellitus

Research paper thumbnail of Healthy and Active Ageing

Healthy and Active Ageing: Human Population Ageing the income security domain with a low proporti... more Healthy and Active Ageing: Human Population Ageing the income security domain with a low proportion, where is transforming economies and societies across the 5% of older people have an income of less than half of world. Japan has the highest proportion of older adults the country's average income. Health domain rank of globally. 8 % of World's population were above 65 years India is the lowest, at 85 of 91 countries with a life in 2010 and is predicted to be 16% by 2050. Decline in expectancy of another 17 years at age 60, the lowest in fertility and improvement in longevity are the factors South Asia (3). In the employment and education domain, observed among most of the developing countries. India ranks at 73 with 20% of the population aged 60 and These countries may grow old before they grow rich. over having secondary or higher education. Unusually India's older population will be 227million by 2050 (1). high burden of healthcare costs is observed in India, i.e. enab...

Research paper thumbnail of Determination of Stress among Women by Discriminant Function Analysis in Sub-Urban area of South Chennai , India

Stress is one of the prime factor for most of the illness in human‟s life. The aim of this study ... more Stress is one of the prime factor for most of the illness in human‟s life. The aim of this study was to construct Discriminant Function with its Score from STRESS levels measured on 200 women of reproductive age group. A CrossSectional, Sample Household Survey was conducted in Sub-Urban Chennai over a period of 6 months. The data was collected on first hand by Personal Interview method in presence of the Community Physician and Psychiatrist. Statistically we observed a Prevalence of 69.5% women with Stress and was significantly high among the Age <30 years & those with BMI<25 and majority of the participants were housewife. Discriminant Function Score of 0.41 with a Canonical Correlation = 0.78; Wilk‟s Lambda = 0.392 & χ =167.91(P=0.000) by „Enter method‟ and DF Score of 0.35 with a Canonical Correlation = 0.73; Wilk‟s Lambda = 0.465 & χ =145.07 (P=0.000) by „Step wise method‟ indicates that the two discriminant functions does better than chance at separating women „with‟ and ...

Research paper thumbnail of Effect of Angiotensin Converting Enzyme Inhibitors / Angiotensin Receptor Blockers, Beta Blockers and Calcium Channel Blockers on Exercise Induced Hypertension- a Retrospective Study

Objective: To test the hypothesis that angiotensin converting enzyme inhibitors (ACEi) affect sol... more Objective: To test the hypothesis that angiotensin converting enzyme inhibitors (ACEi) affect soluble tumor-necrosisfactor-related apoptosis-inducing ligand (sTRAIL) and this interaction is associated with less in-drug-eluting-stent (DES) neointimal hyperplasia following percutaneous coronary intervention (PCI). Methods: From our database of patients with elective PCI and baseline intravascular ultrasound (IVUS) evaluation of the implanted DES, we randomly selected 60 patients who were prescribed an ACEi and 60 matched controls, who did not receive an ACEi following PCI. All patients underwent coronary angiography and IVUS. sTRAIL was measured in samples from the stented coronary artery and a peripheral vein. Results: sTRAIL concentration was higher in the ACEi group, both in coronary and peripheral samples: 104 [78-139] pg/ml versus 63 [45-100] pg/ml (P < 0.001) and 99 [73-135] pg/ml versus 69 [49-103] pg/ml (P ¼ 0.002), respectively. There was an inverse association (standardized beta À0.760; P < 0.001) between sTRAIL and lumen area loss in both treatment groups. In the multivariable analysis, log(sTRAIL) was an independent negative predictor of lumen area loss (standardized beta À0.660, adjusted 95% confidence interval À0.722 to À0.466). Conclusions: Treatment with ACEi was associated with higher sTRAIL levels and lower lumen area loss in the IVUS evaluation of implanted DES. sTRAIL levels were negatively associated with in-stent neointima hyperplasia in these postPCI patients.

Research paper thumbnail of Breastfeeding practice and knowledge among women attending primary health-care centers in Riyadh 2016

Journal of Family Medicine and Primary Care, 2017

Introduction: Breast milk is the best natural essential nutrition to newborns and infants. Howeve... more Introduction: Breast milk is the best natural essential nutrition to newborns and infants. However, the practice of breastfeeding (BF) has declined in Saudi Arabia. Objective: The objective of this study was to assess the knowledge and practice of BF with their determinants among mothers in Riyadh. Materials and Methods: In this cross-sectional study, 252 mothers attending the well-baby clinics in Riyadh from March 2016 to May 2017 were selected randomly with their consent and studied by a standardized questionnaire. Results: Of the 252 women, 69.4% were 25–35 years of age and 56.7% with a bachelor degree or higher education. Nearly 75% mothers had education on BF before our study. Mixed feeding was the most preferred method (51.6%) followed by artificial milk (29.4%). The most reported reason for discontinuing BF was breast milk insufficiency (37.3%) and of breastfeed continuation was their perceived benefit (36.6%). Excellent knowledge was observed among 12.7%, good knowledge in 57.1%, and unsatisfactory level in 30.2% mothers. The regression model shows that high school education improved the knowledge by 10.9 points (P = 0.024) and undergraduate by 18.7 points (P value = 0.001) when compared to women who were literate. Women with parity >5 improved knowledge score by 17.3 points (P < 0.001). Conclusion: We observed that majority (57.1%) of Saudi mothers had a moderate level of knowledge on BF benefits and 19% had practiced exclusive BF. There is a need for better educational programs to increase awareness on its benefits for the health situation in the country on the long term.

Research paper thumbnail of Primary school female teachers' knowledge, attitude, and practice toward students with epilepsy in Riyadh, Saudi Arabia

Journal of Family Medicine and Primary Care, 2018

Background: Epilepsy is the most neurological condition prevalent in humanity and it is associate... more Background: Epilepsy is the most neurological condition prevalent in humanity and it is associated with stigma and discrimination. Knowledge and practice of primary care teachers toward students with epilepsy, especially at young age, is imperative for their development. Objectives: This study was designed to assess the level of knowledge, attitude, and practice of female primary school teachers toward students with epilepsy in Riyadh, Saudi Arabia. Subjects and Methods: In this cross-sectional study, 582 female primary school teachers had volunteered. They were assessed on their knowledge, attitude, and practice toward students with epilepsy using a self-administrated questionnaire. The questionnaire was cross-culturally validated before the distribution. Results: The results suggest above-average familiarity with epilepsy (79.2%). Younger teachers are less likely to associate epilepsy with retardation (P = 0.038). In general, the attitude was positive among the teachers, and 36.9% felt that the students should be treated normally and 63.1% with compassion toward them. Only 14.3% answered that epileptic students should be transferred to special need schools. Highly educated teachers were less likely to feel that epileptic students can cause problems (P = 0.038). The practice was poor with 31.8% expressed the ability to provide first aid to epileptic students. Only 27.5% accepted to give the students prescribed medications. Conclusion: The knowledge about epilepsy needs improvement among primary school teachers in Riyadh. Public level interventions through proper courses can provide a leverage. The higher level of knowledge can be pivotal in increasing the positive attitude and practice of teachers toward epileptic students.

Research paper thumbnail of RAMSAY Sedation Scale and Richmond Agitation Sedation Scale (RASS): A Cross Sectional Study

Health Science Journal, 2018

Background: Many sedation scales and tools have been developed and compared for validity in criti... more Background: Many sedation scales and tools have been developed and compared for validity in critically ill patients. Objective: The aim of this study is to compare the reliability of two sedation scales; RAMSAY sedation scale and Richmond Agitation Sedation Scale (RASS) in the adult intensive care unit. Methods: 290 patients in intensive care unit were recruited for the study and were independently assessed for sedation effect by investigator and bedside nurses simultaneously using RAMSAY scale and RASS scale. Results: Agreement between the nurse and researcher scores on RAMSAY scale (weighted κ=0.449, p<0.001) indicating weak level of agreement. Agreement between the nurse and researcher on RASS scale (weighted κ=0.879, p<0.001) indicating strong level of agreement. Cronbach's alpha analysis showed that 10 items of RASS had excellent level of internal consistency (α=0.989) compared to good level of internal consistency of RAMSAY scale (α =0.828). Conclusion: RASS showed excellent inter-rater agreement compared to weak inter-rater agreement of RAMSAY scale. The results also support that RASS has consistent agreement with clinical observation and practice among different observers. The results suggest that use of RASS is linked to more reliable assessment of sedation levels in the ICU.

Research paper thumbnail of An Automated Method for Segmenting Brain Tumors on MRI Images

Biomedical Engineering, 2017

Research paper thumbnail of Complications After Posterior Acetabular Wall Internal Fixation – Avascular Necrosis and Nonunion

International Journal of Advanced Research, 2017

Introduction: Serious orthopaedics injuries caused by high impact trauma due to road traffic acci... more Introduction: Serious orthopaedics injuries caused by high impact trauma due to road traffic accidents are more prevalent in Saudi Arabia. Fractures of posterior wall are the most common type of acetabulum fractures. The outcome after surgical management of acetabular fracture is primarily related to the quality of articular reduction. This management is the most challenging task for surgeons. Methodology: A retrospective cohort study was conducted in a tertiary care hospital, Riyadh, Saudi Arabia. All patients who underwent internal fixation for posterior wall acetabular fracture from October 2013 to September 2015 were included in the study. Post-surgical outpatient evaluation was done clinically by Merle D' Aubigne Y Postel-hip functional evaluation score and radiological assessment using Ficat classification for staging of avascular necrosis of femoral head. Principal results: With increase in age, the function of hip declined. The step in fixation was found significantly associated with avascular necrosis (p = 0.020) and nonunion (p =0.020). The gap was found significantly associated with nonunion only (p= 0.001). Conclusions: Delay in surgery should be avoided if surgical management is decided for posterior acetabular wall fracture. Adequate surgical reduction of fracture of posterior acetabular wall is necessary. Screw seems to be a better choice of implant until further new evidence is received. A randomized controlled trial is needed to evaluate and compare different management options for fracture of posterior acetabular wall and to set standard guidelines for future.

Research paper thumbnail of Body mass index values for term newborns and its correlation with other anthropometric surrogates

International Journal of Contemporary Pediatrics, 2016

Background: Body mass index is a better tool as it relates two anthropometric measures-Weight and... more Background: Body mass index is a better tool as it relates two anthropometric measures-Weight and Length. This study aims at identifying the mean BMI in term new-borns in Asian population and also the correlation between BMI and other anthropometric surrogates for birth weight. Methods: Cross Sectional study was conducted in a tertiary care hospital by taking anthropometric measurements for 339 consecutive term newborns, born in the institution. Mean BMI was 11.784 ±1.7. Moderate Positive correlation was observed between BMI and Mid Arm Circumference (r= +0.401; P=0.000). Results: The cut off value for BMI to identify LBW was 13. Mid Arm Circumference, Chest circumference and Head circumference correlated well with BMI. Conclusions: By trial and error method of analysis we recommend BMI value of 13 as a cut off for identifying low birth weight infants. BMI is seen to be better than Birth weight in assessing body proportion of a new born.

Research paper thumbnail of Oocyte quality and ABO blood group system: are they connected?

International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 2015

Background: Blood groups of women have been associated with infertility and other related conditi... more Background: Blood groups of women have been associated with infertility and other related conditions like diminished ovarian reserve. We have tried to find, if there is any association between blood group of women and the quality of their oocytes. Methods: Present study is a retrospective analysis from the available data of IVF patients on standard ICSI protocols in our tertiary care clinic over 32 months. Oocytes were grouped into GOOD & POOR quality oocytes. Good quality oocytes were further graded into Grade 1, 2, 3. SPSS 15.0 was used for statistical analysis. Results: Good quality oocytes were almost similarly distributed among the blood groups. Among the good quality oocytes, Grade '1' Oocytes were found higher in 'O' blood group women. Conclusions: Blood group alone was found to play no major role in determining the oocyte quality of women.

Research paper thumbnail of Blastocyst culture depends on quality of embryos on day 3, not quantity

Middle East Fertility Society Journal, 2015

Abstract Study objective : Our aim was to find whether the number really matters and if good blas... more Abstract Study objective : Our aim was to find whether the number really matters and if good blastocysts can be developed even with less numbers on day 3 provided quality is good. Design : A retrospective analysis of all fresh ICSI cycles with a maximum of 6 embryos on day 3, excluding Donor Oocyte, donor embryo and frozen embryo cycles was done. Setting : A Tertiary Infertility Centre in the metro city Chennai, India. Materials and methods : A total number of 84 ICSI cycles with 320 embryos were categorized into six groups based on the day 3 embryo numbers in each cohort. Main outcome measure : ANOVA was used to compare the mean blastocyst formation between these groups and was statistically significant ( P = 0.000). Diagnostic Efficacy for these groups was tested using F1 Score and Mathew’s Correlation Coefficient. Conclusion : Incidence of blast formation rate for the Case group with embryos (1–3) was observed to be 91.5% and 83.2% for the Control group with embryos (>3) and was significant with an overall pregnancy rate 40.5%. Blastocyst culture is possible even with less numbers on day 3 if the quality of embryos is good.

Research paper thumbnail of The reference intervals for the haematological parameters in healthy adult population of chennai, southern India

Journal of clinical and diagnostic research : JCDR, 2012

The haematological parameters are influenced by various factors like age, ethnicity, diet, geneti... more The haematological parameters are influenced by various factors like age, ethnicity, diet, genetic and gender differences and hence it is important to define the specific reference values with regards to the age, gender and the region. The indices like the Red Cell Distribution Width (RDW), the Mean Platelet Volume (MPV) and the Platelet Distribution Width (PDW) are newer haematological parameters which are calculated by automated haematology analyzers. There is an increasing evidence that these are clinically valuable bio markers. But not many studies have estimated the reference intervals for these parameters in our population. Our primary objective was to identify the gender specific reference intervals for RDW, MPV, PDW and other haematological parameters for the healthy adult population of our region. We also aimed at comparing the study reference intervals with the existing reference ranges. A retrospective review of 2443 medical case sheets of the individuals who attended the...

Research paper thumbnail of Domestic microwave versus conventional tissue processing: a quantitative and qualitative analysis

Journal of clinical and diagnostic research : JCDR, 2013

Microwave irradiation has been tried as a replacement for the conventional tissue processing tech... more Microwave irradiation has been tried as a replacement for the conventional tissue processing technique in histopathology laboratories for quite some time. Studies have shown that Domestic Microwave Tissue Processing (DMWTP) provides a faster delivery of the tissue sections with a morphology which is similar to that which is seen Conventional Tissue Processing (CTP). But many laboratories still confine the domestic microwave tissue processing method only to the handle selected specimens, for which urgent reports are needed. One of the probable reasons is that, understanding about the number of tissue sections which can be processed using a microwave oven at a time, with the appropriate quality, still remains unclear. The aim of this study was to quantitatively analyze the optimum number of samples that a domestic microwave could process at a time, as well as to qualitatively analyze the morphological outcome of those tissue sections with that of conventional processing. This study wa...

Research paper thumbnail of ISSN 2347-954X (Print) Stress among Women in Sub-Urban area of South Chennai, India

Abstract: The aim of this study was to estimate the Prevalence of stress among 200 women of repro... more Abstract: The aim of this study was to estimate the Prevalence of stress among 200 women of reproductive age. It"s a Cross Sectional Study in Sub-Urban Chennai with information"s on demographic and stress collected by personal interview method using a structured questionnaire from women of age (18-45) years after obtaining the written informed consent. The important findings are Prevalence was 69.5% and Women with younger Age <30 and BMI <25 were found to be at major risk of stress with statistical significance. The prevalence of STRESS in south Chennai women is slightly lesser than those found in earlier studies. We suggest that the "Stressed Women at Risk group for Illness" should be identified from the community at the earlier age for health assistance to lead a better quality of life.

Research paper thumbnail of Tool Development in Health Care Research

Measures of Population Health would need to be compatible across nation and cultures to serve as ... more Measures of Population Health would need to be compatible across nation and cultures to serve as measures for making global health policy. Health state valuations on the basis of utility instruments such as rating scales, ex. the Visual Analog Scale or methods such as personal trade-off, time trade-off and standard gamble are one of the critical inputs that contribute to the calculation of summary measures of population health. These methods are supposed to assess an individual's valuation of hypothetical health states in terms of a single number indicating the value placed on a health state relative to perfect health or death.

Research paper thumbnail of Testing of Defects per Million Medication Orders as a SMART Indicator for Monitoring Medication Safety in Admission and Discharge Orders

Global Journal on Quality and Safety in Healthcare, 2021

Introduction The study investigated the use of defects per million medication orders (DPMMO) as a... more Introduction The study investigated the use of defects per million medication orders (DPMMO) as a SMART (specific, measurable, achievable, realistic, and timely) indicator for monitoring medication safety in admission and discharge orders. The study aimed to develop and test a new indicator as an investigator of medication safety. Methods The study was conducted in 2018 at King Saud Medical City in Riyadh City in Saudi Arabia. A retrospective cross-sectional design was used. The research sample had 292 patients. The selected medication orders included two types of medication orders (admission and discharge order). After sufficient data had been gathered from the hospitals, a statistical analysis was carried out. Results Analysis of admission and discharge orders indicated that defects per million opportunities (DPMO) and DPMMO count were slightly low, while the sigma level for admission orders was slightly high. Thus, the admission order process was slightly better than the discharg...

Research paper thumbnail of Pressure Injury Prevalence and Risk Factors among Adult Critically Ill Patients at a Large Intensive Care Unit

Purpose: To know the pressure injuries prevalence, locations, and stages in the intensive care un... more Purpose: To know the pressure injuries prevalence, locations, and stages in the intensive care unit and its associated factors. Design: Cross-sectional study. Method: Prevalence study was conducted over six months, from December 2015 to May 2016. Findings: Prevalence of pressure injury was 35.7% (154 patients out of 431 had at least one pressure injury), this is excluding stage one pressure injuries and the medical device related pressure injuries. The sacrum was the most frequent location of PIs followed by trochanter, ear, heel, buttocks, and ankle. Stage two pressure injuries was the most commonly observed among critically ill patients. We found a significant association between the pressure injuries and the age of patient, Body mass index, and Length of stay. Conclusion: Measuring prevalence of pressure injuries among critically ill patients is crucial and should be highlighted for all critical care sittings.

Research paper thumbnail of Delirium Incidence and Risk Factors in Adult Critically Ill Patients in Saudi Arabia

Background: Delirium in intensive care units (ICUs) is associated with long ICU stay, long hospit... more Background: Delirium in intensive care units (ICUs) is associated with long ICU stay, long hospital stay and increased costs of treatment. Unfortunately, delirium in ICU is significantly underestimated and overlooked by healthcare providers. Aims: The aim of this tudy is to determine the incidence and associated risk factors of delirium among critically ill patients in Saudi Arabia. Methods: This is a prospective study. Patients were assessed for delirium using the confusion assessment method for the ICU. Delirium was the independent variable in this study. Results: Fifty-nine patients (17.3%) showed positive delirium at least once compared to 283 patients (82.7%) who did not show positive delirium. Certain factors for delirium found to be significantly correlated with delirium (P < 0.005); including receiving sedation, mode of sedation, receiving mechanical ventilation, resistance to mechanical ventilator, and baseline Glasgow Coma Scale. Conclusion: Delirium occurred in >17%...

Research paper thumbnail of Radiographic evaluation of bone density in dentulous and edentulous patients in Riyadh, KSA

Nigerian Journal of Clinical Practice, 2020

Background: The Cone Beam Computed Tomography (CBCT) is currently being used as the most common d... more Background: The Cone Beam Computed Tomography (CBCT) is currently being used as the most common diagnostic method to evaluate the bone density of the maxilla and the mandible for planning dental implant. Aim: The aim of the study is to check the quantitative alveolar bone density in complete or partial edentulous and dentulous male and female patients among Riyadh sample population in Saudi Arabia. Materials and Methods: The study involved a cross-sectional analysis of 231 consecutive CBCT images of 231 different patients (115 males and 116 females). The scans were of Saudi National patients who were partially or completely edentulous without any bone infections in the maxilla and the mandible. The findings are presented as descriptive statistics and inferential statistics: student -t-test for two group means, ANOVA for three groups, Post-hoc LSD test for multiple comparisons, Levene statistics for testing the homogeneity of variances and a statistical significance at 5% level. Resu...

Research paper thumbnail of Serum 25(OH)D and type 2 Diabetes mellitus

Research paper thumbnail of Healthy and Active Ageing

Healthy and Active Ageing: Human Population Ageing the income security domain with a low proporti... more Healthy and Active Ageing: Human Population Ageing the income security domain with a low proportion, where is transforming economies and societies across the 5% of older people have an income of less than half of world. Japan has the highest proportion of older adults the country's average income. Health domain rank of globally. 8 % of World's population were above 65 years India is the lowest, at 85 of 91 countries with a life in 2010 and is predicted to be 16% by 2050. Decline in expectancy of another 17 years at age 60, the lowest in fertility and improvement in longevity are the factors South Asia (3). In the employment and education domain, observed among most of the developing countries. India ranks at 73 with 20% of the population aged 60 and These countries may grow old before they grow rich. over having secondary or higher education. Unusually India's older population will be 227million by 2050 (1). high burden of healthcare costs is observed in India, i.e. enab...

Research paper thumbnail of Determination of Stress among Women by Discriminant Function Analysis in Sub-Urban area of South Chennai , India

Stress is one of the prime factor for most of the illness in human‟s life. The aim of this study ... more Stress is one of the prime factor for most of the illness in human‟s life. The aim of this study was to construct Discriminant Function with its Score from STRESS levels measured on 200 women of reproductive age group. A CrossSectional, Sample Household Survey was conducted in Sub-Urban Chennai over a period of 6 months. The data was collected on first hand by Personal Interview method in presence of the Community Physician and Psychiatrist. Statistically we observed a Prevalence of 69.5% women with Stress and was significantly high among the Age <30 years & those with BMI<25 and majority of the participants were housewife. Discriminant Function Score of 0.41 with a Canonical Correlation = 0.78; Wilk‟s Lambda = 0.392 & χ =167.91(P=0.000) by „Enter method‟ and DF Score of 0.35 with a Canonical Correlation = 0.73; Wilk‟s Lambda = 0.465 & χ =145.07 (P=0.000) by „Step wise method‟ indicates that the two discriminant functions does better than chance at separating women „with‟ and ...

Research paper thumbnail of Effect of Angiotensin Converting Enzyme Inhibitors / Angiotensin Receptor Blockers, Beta Blockers and Calcium Channel Blockers on Exercise Induced Hypertension- a Retrospective Study

Objective: To test the hypothesis that angiotensin converting enzyme inhibitors (ACEi) affect sol... more Objective: To test the hypothesis that angiotensin converting enzyme inhibitors (ACEi) affect soluble tumor-necrosisfactor-related apoptosis-inducing ligand (sTRAIL) and this interaction is associated with less in-drug-eluting-stent (DES) neointimal hyperplasia following percutaneous coronary intervention (PCI). Methods: From our database of patients with elective PCI and baseline intravascular ultrasound (IVUS) evaluation of the implanted DES, we randomly selected 60 patients who were prescribed an ACEi and 60 matched controls, who did not receive an ACEi following PCI. All patients underwent coronary angiography and IVUS. sTRAIL was measured in samples from the stented coronary artery and a peripheral vein. Results: sTRAIL concentration was higher in the ACEi group, both in coronary and peripheral samples: 104 [78-139] pg/ml versus 63 [45-100] pg/ml (P < 0.001) and 99 [73-135] pg/ml versus 69 [49-103] pg/ml (P ¼ 0.002), respectively. There was an inverse association (standardized beta À0.760; P < 0.001) between sTRAIL and lumen area loss in both treatment groups. In the multivariable analysis, log(sTRAIL) was an independent negative predictor of lumen area loss (standardized beta À0.660, adjusted 95% confidence interval À0.722 to À0.466). Conclusions: Treatment with ACEi was associated with higher sTRAIL levels and lower lumen area loss in the IVUS evaluation of implanted DES. sTRAIL levels were negatively associated with in-stent neointima hyperplasia in these postPCI patients.

Research paper thumbnail of Breastfeeding practice and knowledge among women attending primary health-care centers in Riyadh 2016

Journal of Family Medicine and Primary Care, 2017

Introduction: Breast milk is the best natural essential nutrition to newborns and infants. Howeve... more Introduction: Breast milk is the best natural essential nutrition to newborns and infants. However, the practice of breastfeeding (BF) has declined in Saudi Arabia. Objective: The objective of this study was to assess the knowledge and practice of BF with their determinants among mothers in Riyadh. Materials and Methods: In this cross-sectional study, 252 mothers attending the well-baby clinics in Riyadh from March 2016 to May 2017 were selected randomly with their consent and studied by a standardized questionnaire. Results: Of the 252 women, 69.4% were 25–35 years of age and 56.7% with a bachelor degree or higher education. Nearly 75% mothers had education on BF before our study. Mixed feeding was the most preferred method (51.6%) followed by artificial milk (29.4%). The most reported reason for discontinuing BF was breast milk insufficiency (37.3%) and of breastfeed continuation was their perceived benefit (36.6%). Excellent knowledge was observed among 12.7%, good knowledge in 57.1%, and unsatisfactory level in 30.2% mothers. The regression model shows that high school education improved the knowledge by 10.9 points (P = 0.024) and undergraduate by 18.7 points (P value = 0.001) when compared to women who were literate. Women with parity >5 improved knowledge score by 17.3 points (P < 0.001). Conclusion: We observed that majority (57.1%) of Saudi mothers had a moderate level of knowledge on BF benefits and 19% had practiced exclusive BF. There is a need for better educational programs to increase awareness on its benefits for the health situation in the country on the long term.

Research paper thumbnail of Primary school female teachers' knowledge, attitude, and practice toward students with epilepsy in Riyadh, Saudi Arabia

Journal of Family Medicine and Primary Care, 2018

Background: Epilepsy is the most neurological condition prevalent in humanity and it is associate... more Background: Epilepsy is the most neurological condition prevalent in humanity and it is associated with stigma and discrimination. Knowledge and practice of primary care teachers toward students with epilepsy, especially at young age, is imperative for their development. Objectives: This study was designed to assess the level of knowledge, attitude, and practice of female primary school teachers toward students with epilepsy in Riyadh, Saudi Arabia. Subjects and Methods: In this cross-sectional study, 582 female primary school teachers had volunteered. They were assessed on their knowledge, attitude, and practice toward students with epilepsy using a self-administrated questionnaire. The questionnaire was cross-culturally validated before the distribution. Results: The results suggest above-average familiarity with epilepsy (79.2%). Younger teachers are less likely to associate epilepsy with retardation (P = 0.038). In general, the attitude was positive among the teachers, and 36.9% felt that the students should be treated normally and 63.1% with compassion toward them. Only 14.3% answered that epileptic students should be transferred to special need schools. Highly educated teachers were less likely to feel that epileptic students can cause problems (P = 0.038). The practice was poor with 31.8% expressed the ability to provide first aid to epileptic students. Only 27.5% accepted to give the students prescribed medications. Conclusion: The knowledge about epilepsy needs improvement among primary school teachers in Riyadh. Public level interventions through proper courses can provide a leverage. The higher level of knowledge can be pivotal in increasing the positive attitude and practice of teachers toward epileptic students.

Research paper thumbnail of RAMSAY Sedation Scale and Richmond Agitation Sedation Scale (RASS): A Cross Sectional Study

Health Science Journal, 2018

Background: Many sedation scales and tools have been developed and compared for validity in criti... more Background: Many sedation scales and tools have been developed and compared for validity in critically ill patients. Objective: The aim of this study is to compare the reliability of two sedation scales; RAMSAY sedation scale and Richmond Agitation Sedation Scale (RASS) in the adult intensive care unit. Methods: 290 patients in intensive care unit were recruited for the study and were independently assessed for sedation effect by investigator and bedside nurses simultaneously using RAMSAY scale and RASS scale. Results: Agreement between the nurse and researcher scores on RAMSAY scale (weighted κ=0.449, p<0.001) indicating weak level of agreement. Agreement between the nurse and researcher on RASS scale (weighted κ=0.879, p<0.001) indicating strong level of agreement. Cronbach's alpha analysis showed that 10 items of RASS had excellent level of internal consistency (α=0.989) compared to good level of internal consistency of RAMSAY scale (α =0.828). Conclusion: RASS showed excellent inter-rater agreement compared to weak inter-rater agreement of RAMSAY scale. The results also support that RASS has consistent agreement with clinical observation and practice among different observers. The results suggest that use of RASS is linked to more reliable assessment of sedation levels in the ICU.

Research paper thumbnail of An Automated Method for Segmenting Brain Tumors on MRI Images

Biomedical Engineering, 2017

Research paper thumbnail of Complications After Posterior Acetabular Wall Internal Fixation – Avascular Necrosis and Nonunion

International Journal of Advanced Research, 2017

Introduction: Serious orthopaedics injuries caused by high impact trauma due to road traffic acci... more Introduction: Serious orthopaedics injuries caused by high impact trauma due to road traffic accidents are more prevalent in Saudi Arabia. Fractures of posterior wall are the most common type of acetabulum fractures. The outcome after surgical management of acetabular fracture is primarily related to the quality of articular reduction. This management is the most challenging task for surgeons. Methodology: A retrospective cohort study was conducted in a tertiary care hospital, Riyadh, Saudi Arabia. All patients who underwent internal fixation for posterior wall acetabular fracture from October 2013 to September 2015 were included in the study. Post-surgical outpatient evaluation was done clinically by Merle D' Aubigne Y Postel-hip functional evaluation score and radiological assessment using Ficat classification for staging of avascular necrosis of femoral head. Principal results: With increase in age, the function of hip declined. The step in fixation was found significantly associated with avascular necrosis (p = 0.020) and nonunion (p =0.020). The gap was found significantly associated with nonunion only (p= 0.001). Conclusions: Delay in surgery should be avoided if surgical management is decided for posterior acetabular wall fracture. Adequate surgical reduction of fracture of posterior acetabular wall is necessary. Screw seems to be a better choice of implant until further new evidence is received. A randomized controlled trial is needed to evaluate and compare different management options for fracture of posterior acetabular wall and to set standard guidelines for future.

Research paper thumbnail of Body mass index values for term newborns and its correlation with other anthropometric surrogates

International Journal of Contemporary Pediatrics, 2016

Background: Body mass index is a better tool as it relates two anthropometric measures-Weight and... more Background: Body mass index is a better tool as it relates two anthropometric measures-Weight and Length. This study aims at identifying the mean BMI in term new-borns in Asian population and also the correlation between BMI and other anthropometric surrogates for birth weight. Methods: Cross Sectional study was conducted in a tertiary care hospital by taking anthropometric measurements for 339 consecutive term newborns, born in the institution. Mean BMI was 11.784 ±1.7. Moderate Positive correlation was observed between BMI and Mid Arm Circumference (r= +0.401; P=0.000). Results: The cut off value for BMI to identify LBW was 13. Mid Arm Circumference, Chest circumference and Head circumference correlated well with BMI. Conclusions: By trial and error method of analysis we recommend BMI value of 13 as a cut off for identifying low birth weight infants. BMI is seen to be better than Birth weight in assessing body proportion of a new born.

Research paper thumbnail of Oocyte quality and ABO blood group system: are they connected?

International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 2015

Background: Blood groups of women have been associated with infertility and other related conditi... more Background: Blood groups of women have been associated with infertility and other related conditions like diminished ovarian reserve. We have tried to find, if there is any association between blood group of women and the quality of their oocytes. Methods: Present study is a retrospective analysis from the available data of IVF patients on standard ICSI protocols in our tertiary care clinic over 32 months. Oocytes were grouped into GOOD & POOR quality oocytes. Good quality oocytes were further graded into Grade 1, 2, 3. SPSS 15.0 was used for statistical analysis. Results: Good quality oocytes were almost similarly distributed among the blood groups. Among the good quality oocytes, Grade '1' Oocytes were found higher in 'O' blood group women. Conclusions: Blood group alone was found to play no major role in determining the oocyte quality of women.

Research paper thumbnail of Blastocyst culture depends on quality of embryos on day 3, not quantity

Middle East Fertility Society Journal, 2015

Abstract Study objective : Our aim was to find whether the number really matters and if good blas... more Abstract Study objective : Our aim was to find whether the number really matters and if good blastocysts can be developed even with less numbers on day 3 provided quality is good. Design : A retrospective analysis of all fresh ICSI cycles with a maximum of 6 embryos on day 3, excluding Donor Oocyte, donor embryo and frozen embryo cycles was done. Setting : A Tertiary Infertility Centre in the metro city Chennai, India. Materials and methods : A total number of 84 ICSI cycles with 320 embryos were categorized into six groups based on the day 3 embryo numbers in each cohort. Main outcome measure : ANOVA was used to compare the mean blastocyst formation between these groups and was statistically significant ( P = 0.000). Diagnostic Efficacy for these groups was tested using F1 Score and Mathew’s Correlation Coefficient. Conclusion : Incidence of blast formation rate for the Case group with embryos (1–3) was observed to be 91.5% and 83.2% for the Control group with embryos (>3) and was significant with an overall pregnancy rate 40.5%. Blastocyst culture is possible even with less numbers on day 3 if the quality of embryos is good.

Research paper thumbnail of The reference intervals for the haematological parameters in healthy adult population of chennai, southern India

Journal of clinical and diagnostic research : JCDR, 2012

The haematological parameters are influenced by various factors like age, ethnicity, diet, geneti... more The haematological parameters are influenced by various factors like age, ethnicity, diet, genetic and gender differences and hence it is important to define the specific reference values with regards to the age, gender and the region. The indices like the Red Cell Distribution Width (RDW), the Mean Platelet Volume (MPV) and the Platelet Distribution Width (PDW) are newer haematological parameters which are calculated by automated haematology analyzers. There is an increasing evidence that these are clinically valuable bio markers. But not many studies have estimated the reference intervals for these parameters in our population. Our primary objective was to identify the gender specific reference intervals for RDW, MPV, PDW and other haematological parameters for the healthy adult population of our region. We also aimed at comparing the study reference intervals with the existing reference ranges. A retrospective review of 2443 medical case sheets of the individuals who attended the...

Research paper thumbnail of Domestic microwave versus conventional tissue processing: a quantitative and qualitative analysis

Journal of clinical and diagnostic research : JCDR, 2013

Microwave irradiation has been tried as a replacement for the conventional tissue processing tech... more Microwave irradiation has been tried as a replacement for the conventional tissue processing technique in histopathology laboratories for quite some time. Studies have shown that Domestic Microwave Tissue Processing (DMWTP) provides a faster delivery of the tissue sections with a morphology which is similar to that which is seen Conventional Tissue Processing (CTP). But many laboratories still confine the domestic microwave tissue processing method only to the handle selected specimens, for which urgent reports are needed. One of the probable reasons is that, understanding about the number of tissue sections which can be processed using a microwave oven at a time, with the appropriate quality, still remains unclear. The aim of this study was to quantitatively analyze the optimum number of samples that a domestic microwave could process at a time, as well as to qualitatively analyze the morphological outcome of those tissue sections with that of conventional processing. This study wa...