Dhanasekaraprabu Balasubramanian | All India Institute of Medical Sciences, New Delhi (original) (raw)

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Papers by Dhanasekaraprabu Balasubramanian

Research paper thumbnail of A new femoral fixation device for anterior cruciate ligament reconstruction using the outside-in technique and hamstring tendon graft: A comparison between two devices in cadaveric human knee models

The Knee, Jan 23, 2017

A new device (T-anchor) was developed for ACL reconstruction and is implanted via the outside-in ... more A new device (T-anchor) was developed for ACL reconstruction and is implanted via the outside-in technique using hamstring grafts. The purpose of this study was to compare the T-anchor with the EndoButton Direct. This study was conducted on 30 cadaveric knees (15 matched pairs). There were two groups of 15 each in the T-anchor and EndoButton Direct groups. After the harvest of grafts, fixation site profile and graft length were measured by loading the grafts onto both devices. They were then tested on a universal testing machine to assess elongation after cyclic loading, load to failure, ultimate load, and mode of failure. The fixation site profile was lower in the T-anchor group than in the EndoButton Direct group (2.3±0.4mm vs. 4.7±1.0mm, P<0.001). The length of the graft-device complex of the T-anchor specimens was longer than that of the EndoButton Direct specimens (125.0±8.9mm vs. 115.0±8.7mm, P<0.001). The mean cyclic elongation was lower for the T-anchor group when comp...

Research paper thumbnail of Plaster of Paris: Past, present and future

Journal of Clinical Orthopaedics and Trauma, 2013

No other object is as closely associated with the branch of orthopaedics as Plaster of Paris or P... more No other object is as closely associated with the branch of orthopaedics as Plaster of Paris or POP as we commonly call it. Orthopaedicians have been associated with POP just like cardiologists with ECG and the plastic surgeons with Humby's knife. Its use is ubiquitous and we put it to such a myriad of uses that the list is endless.

Research paper thumbnail of What is the Ideal Route of Administration of Tranexamic Acid in TKA? A Randomized Controlled Trial

Clinical orthopaedics and related research, Jan 10, 2017

TKA commonly involves substantial blood loss and tranexamic acid has been used to reduce blood lo... more TKA commonly involves substantial blood loss and tranexamic acid has been used to reduce blood loss after TKA. Numerous clinical trials have documented the efficacy and safety of intravenous (IV) or intraarticular (IA) use of tranexamic acid. Combined administration of tranexamic acid also has been suggested; however, there is no consensus regarding the ideal route of tranexamic acid administration. (1) To compare the efficacy of tranexamic acid in terms of total blood loss and the allogeneic transfusion rate among three routes of administration: IV alone, IA alone, and combined IV and IA. (2) To compare these regimens in terms of venous thromboembolism (VTE) and the frequency of wound complications. In total, 376 patients undergoing TKA between March 2014 and March 2015 were randomized to four groups by the route of tranexamic acid administration: IV only, IA only, low-dose combined (IV + IA injection of 1 g), and high-dose combined (IV + IA injection of 2 g). The calculated total ...

Research paper thumbnail of The Management of Cervical Spine Injuries – A Literature Review

Orthopedic Research and Reviews, 2021

Due to the inherent bony instability of the cervical spine, there is an over-reliance on ligament... more Due to the inherent bony instability of the cervical spine, there is an over-reliance on ligamentous structures for stability, making this segment of the vertebral column most prone to traumatic injuries. The frequently occurring mechanisms of injury include axial compression, hyper-flexion, hyper-extension, and rotational type injuries. Good pre-hospital care and a thorough assessment in the emergency department of patients suspected to have a cervical spine injury (CSI) leads to improved clinical outcomes. The objective of the initial evaluation of a patient with a suspected CSI is to identify the presence of injuries through thorough clinical and radiologic assessments as missed injuries are potentially catastrophic. The treatment of cervical spine injuries can be conservative, pharmacological, or surgical, and aims to halt SCI progression, stabilize the spine, and to allow rehabilitation of the patient.

Research paper thumbnail of Plaster of Paris : Past, Present and Future

Journal of clinical orthopaedics and Trauma, 2013

No other object is as closely associated with the branch of orthopaedics as Plaster of Paris or P... more No other object is as closely associated with the branch of orthopaedics as Plaster of Paris or POP as we commonly call it. Orthopaedicians have been associated with POP just like cardiologists with ECG and the plastic surgeons with Humby's knife. Its use is ubiquitous and we put it to such a myriad of uses that the list is endless.

Research paper thumbnail of A new femoral fixation device for anterior cruciate ligament reconstruction using the outside-in technique and hamstring tendon graft: A comparison between two devices in cadaveric human knee models

The Knee, 2017

Background: A new device (T-anchor) was developed for ACL reconstruction and is implanted via the... more Background: A new device (T-anchor) was developed for ACL reconstruction and is implanted via the outside-in technique using hamstring grafts. The purpose of this study was to compare the T-anchor with the EndoButton Direct. Methods: This study was conducted on 30 cadaveric knees (15 matched pairs). There were two groups of 15 each in the T-anchor and EndoButton Direct groups. After the harvest of grafts, fixation site profile and graft length were measured by loading the grafts onto both devices. They were then tested on a universal testing machine to assess elongation after cyclic loading, load to failure, ultimate load, and mode of failure. Results: The fixation site profile was lower in the T-anchor group than in the EndoButton Direct group (2.3 ± 0.4 mm vs. 4.7 ± 1.0 mm, P b 0.001). The length of the graft-device complex of the T-anchor specimens was longer than that of the EndoButton Direct specimens (125.0 ± 8.9 mm vs. 115.0 ± 8.7 mm, P b 0.001). The mean cyclic elongation was lower for the T-anchor group when compared with the EndoButton Direct group (2.4 ± 0.6 mm vs. 3.9 ± 2.6 mm, P = 0.015). There was no statistically significant difference in ultimate load and load to failure between the T-anchor and EndoButton Direct groups. For mode of failure, the T-anchor fared better (P = 0.013) with all failures attributed to specimens. Conclusions: In this cadaveric study, the new device, T-anchor, performed better than the EndoButton Direct with respect to the above-mentioned study parameters except for ultimate load and load to failure.

Research paper thumbnail of What is the Ideal Route of Administration of Tranexamic Acid in TKA? A Randomized Controlled Trial

Clin Orthop Relat Res, 2017

Background TKA commonly involves

Research paper thumbnail of A new femoral fixation device for anterior cruciate ligament reconstruction using the outside-in technique and hamstring tendon graft: A comparison between two devices in cadaveric human knee models

The Knee, Jan 23, 2017

A new device (T-anchor) was developed for ACL reconstruction and is implanted via the outside-in ... more A new device (T-anchor) was developed for ACL reconstruction and is implanted via the outside-in technique using hamstring grafts. The purpose of this study was to compare the T-anchor with the EndoButton Direct. This study was conducted on 30 cadaveric knees (15 matched pairs). There were two groups of 15 each in the T-anchor and EndoButton Direct groups. After the harvest of grafts, fixation site profile and graft length were measured by loading the grafts onto both devices. They were then tested on a universal testing machine to assess elongation after cyclic loading, load to failure, ultimate load, and mode of failure. The fixation site profile was lower in the T-anchor group than in the EndoButton Direct group (2.3±0.4mm vs. 4.7±1.0mm, P<0.001). The length of the graft-device complex of the T-anchor specimens was longer than that of the EndoButton Direct specimens (125.0±8.9mm vs. 115.0±8.7mm, P<0.001). The mean cyclic elongation was lower for the T-anchor group when comp...

Research paper thumbnail of Plaster of Paris: Past, present and future

Journal of Clinical Orthopaedics and Trauma, 2013

No other object is as closely associated with the branch of orthopaedics as Plaster of Paris or P... more No other object is as closely associated with the branch of orthopaedics as Plaster of Paris or POP as we commonly call it. Orthopaedicians have been associated with POP just like cardiologists with ECG and the plastic surgeons with Humby's knife. Its use is ubiquitous and we put it to such a myriad of uses that the list is endless.

Research paper thumbnail of What is the Ideal Route of Administration of Tranexamic Acid in TKA? A Randomized Controlled Trial

Clinical orthopaedics and related research, Jan 10, 2017

TKA commonly involves substantial blood loss and tranexamic acid has been used to reduce blood lo... more TKA commonly involves substantial blood loss and tranexamic acid has been used to reduce blood loss after TKA. Numerous clinical trials have documented the efficacy and safety of intravenous (IV) or intraarticular (IA) use of tranexamic acid. Combined administration of tranexamic acid also has been suggested; however, there is no consensus regarding the ideal route of tranexamic acid administration. (1) To compare the efficacy of tranexamic acid in terms of total blood loss and the allogeneic transfusion rate among three routes of administration: IV alone, IA alone, and combined IV and IA. (2) To compare these regimens in terms of venous thromboembolism (VTE) and the frequency of wound complications. In total, 376 patients undergoing TKA between March 2014 and March 2015 were randomized to four groups by the route of tranexamic acid administration: IV only, IA only, low-dose combined (IV + IA injection of 1 g), and high-dose combined (IV + IA injection of 2 g). The calculated total ...

Research paper thumbnail of The Management of Cervical Spine Injuries – A Literature Review

Orthopedic Research and Reviews, 2021

Due to the inherent bony instability of the cervical spine, there is an over-reliance on ligament... more Due to the inherent bony instability of the cervical spine, there is an over-reliance on ligamentous structures for stability, making this segment of the vertebral column most prone to traumatic injuries. The frequently occurring mechanisms of injury include axial compression, hyper-flexion, hyper-extension, and rotational type injuries. Good pre-hospital care and a thorough assessment in the emergency department of patients suspected to have a cervical spine injury (CSI) leads to improved clinical outcomes. The objective of the initial evaluation of a patient with a suspected CSI is to identify the presence of injuries through thorough clinical and radiologic assessments as missed injuries are potentially catastrophic. The treatment of cervical spine injuries can be conservative, pharmacological, or surgical, and aims to halt SCI progression, stabilize the spine, and to allow rehabilitation of the patient.

Research paper thumbnail of Plaster of Paris : Past, Present and Future

Journal of clinical orthopaedics and Trauma, 2013

No other object is as closely associated with the branch of orthopaedics as Plaster of Paris or P... more No other object is as closely associated with the branch of orthopaedics as Plaster of Paris or POP as we commonly call it. Orthopaedicians have been associated with POP just like cardiologists with ECG and the plastic surgeons with Humby's knife. Its use is ubiquitous and we put it to such a myriad of uses that the list is endless.

Research paper thumbnail of A new femoral fixation device for anterior cruciate ligament reconstruction using the outside-in technique and hamstring tendon graft: A comparison between two devices in cadaveric human knee models

The Knee, 2017

Background: A new device (T-anchor) was developed for ACL reconstruction and is implanted via the... more Background: A new device (T-anchor) was developed for ACL reconstruction and is implanted via the outside-in technique using hamstring grafts. The purpose of this study was to compare the T-anchor with the EndoButton Direct. Methods: This study was conducted on 30 cadaveric knees (15 matched pairs). There were two groups of 15 each in the T-anchor and EndoButton Direct groups. After the harvest of grafts, fixation site profile and graft length were measured by loading the grafts onto both devices. They were then tested on a universal testing machine to assess elongation after cyclic loading, load to failure, ultimate load, and mode of failure. Results: The fixation site profile was lower in the T-anchor group than in the EndoButton Direct group (2.3 ± 0.4 mm vs. 4.7 ± 1.0 mm, P b 0.001). The length of the graft-device complex of the T-anchor specimens was longer than that of the EndoButton Direct specimens (125.0 ± 8.9 mm vs. 115.0 ± 8.7 mm, P b 0.001). The mean cyclic elongation was lower for the T-anchor group when compared with the EndoButton Direct group (2.4 ± 0.6 mm vs. 3.9 ± 2.6 mm, P = 0.015). There was no statistically significant difference in ultimate load and load to failure between the T-anchor and EndoButton Direct groups. For mode of failure, the T-anchor fared better (P = 0.013) with all failures attributed to specimens. Conclusions: In this cadaveric study, the new device, T-anchor, performed better than the EndoButton Direct with respect to the above-mentioned study parameters except for ultimate load and load to failure.

Research paper thumbnail of What is the Ideal Route of Administration of Tranexamic Acid in TKA? A Randomized Controlled Trial

Clin Orthop Relat Res, 2017

Background TKA commonly involves