İbrahim Basarici | Akdeniz University (original) (raw)
Papers by İbrahim Basarici
The International Journal of Cardiovascular Imaging
Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2007
Say›n Editör, Derginizin son say›s›nda yay›nlanan say›n Dr. Ö. Avflar ve ark.'a ait "Ko... more Say›n Editör, Derginizin son say›s›nda yay›nlanan say›n Dr. Ö. Avflar ve ark.'a ait "Koroner yavafl ak›m ile karotis intima-media kal›nl›¤› aras›ndaki iliflki" bafll›kl› makaleyi (1) ilgi ve dikkatle okudum. Benzer hasta popülasyonu üzerine çal›flmakta olduumdan dolay› kendi çal›flma tasar›m›m ile k›- yaslama olana¤› bulduum bu çal›flmaya iliflkin akl›mda soru iflaretleri b›rakan noktalar› (benzer çal›flma yapacak araflt›r›c›lara da uyar›c› ve yol gösterici olaca¤›n› düflünerek) paylaflma ihtiyac› duydum. Öncelikle çal›flmada koroner yavafl ak›m› (KYA) belirlemek amac›yla kullan›lan Gibson'un TIMI kare say›s› yöntemi için at›fta bulunulan "8" nu- maral› kayna¤›n (2) at›fta bulunulan konuyla iliflkisiz olduu (muhtemel diz- gi veya bask› hatas› ?) dikkatimi çekti. Buradan hareketle literatürde TIMI kare say›s›n› ele alan çal›flmalar›n temel at›f kayna¤› olan Gibson'un oriji- nal makalesine (3) ulaflt›m. Bu makalede hiç infarktüs geçirmemifl ve epi- kardiyal koroner arter darl›¤› saptanmayan (yazarlar›n çal›flmas›nda nor- mal koroner anjiyografi olarak belirtilen gruba özdefl) hastalarda sol ön inen koroner arter (LAD), sirkumfleks arter (Cx), sakoroner arter (RCA) ve düzeltilmifl LAD ak›m› için bulunan TIMI kare say›lar› s›ras›yla flöyledir: 36.2±2.6 (LAD), 22.2±4.1 (Cx), 20.4±3.0 (RCA), 21.1±1.5 (dLAD). Yazarlar›n yöntemi incelendiinde Gibson' un referans deerlerinin "standart ortala- malar›n›n 2 kare fazlas›n›n" KYA kriteri olarak al›nd›¤› anlafl›lmaktad›r. Fa- kat yazarlar›n burada LAD için belirtmifl olduklar› referans deer 38 olup, Gibson'un orijinal makalesindekinden farkl›d›r (?). "Standart ortalama de- ¤erlerin 2 fazlas›" tan›m› ile yazarlar›n LAD, Cx ve RCA için belirttikleri 38, 30 ve 26 deerlerine ulafl›lamad›¤›n› gördü¤ümden bu tan›m›n bir "ifade hatas›" olduunu ve asl›nda Gibson'un bulduu "ortalama deerlerin 2 standart sapma üzerinde" olan TIMI kare deerlerinin (ortalama +(stan- dart sapma x 2 )) KYA kriteri olarak kabul edildiini varsayd›m. Böylece (küsuratlar yuvarlanmak suretiyle) Cx için (22+(4x2)) 30 ve RCA için (20+(3x2)) 26 deerlerinin nas›l elde edildiini saptad›m. Ancak bu yöntem- le yine de LAD'de KYA tan›s› için yazarlar›n belirledii 38 deerine ulafl- mak mümkün deildir (Çünkü (36+(2x2))= 40 olmal›yd›). Bu nedenle LAD için KYA kriterinin neden dier koroner arterler için önerilen yöntemden farkl› olduunu ve nas›l hesapland›¤›n› merak etmekteyim. Ayr›ca önemli bir nokta da at›fta bulunulan Gibson'un çal›flmas›n›n 'sineanjiyografi' dö- neminde yap›lm›fl olmas› ve bu görüntülerin 30 pencere/saniye h›zda kay- dedilmifl olduklar›d›r. Oysa yazarlar çal›flmada bilgisayar disklerine kayde- dilen say›sal görüntüler üzerinde inceleme yapm›fllard›r. Bilindii gibi bu tür say›sal anjiyografi cihazlar› 30 pencere/saniye h›z›n alt›nda bir h›zda (genellikle 15-25 pencere/saniye) kay›t yapmaktad›rlar. Bu nedenle yazar- lar›n inceledikleri görüntülerin kay›t h›z›n›n makalede mutlaka belirtilmesi gerekir. Çünkü farkl› kay›t h›zlar›nda yap›lan görüntüleme deerlerinin ay- n› kriterlere göre ele al›narak incelenmesi hatal› olacakt›r. Bu durumda bir karfl›laflt›rma yapmak tamamen imkans›z olmay›p, yazarlar›n kay›t h›zlar›- na göre bulduklar› TIMI kare say›s›n› 30 pencere/saniye h›zl› kay›da oran- layarak dönüfltürmek suretiyle karfl›laflt›rmalar› da mümkündür (4). Ayr›ca KYA ile karotis arter intima-medya kal›nl›¤› aras›ndaki iliflki- yi inceleyen bu çal›flmada normal ve yavafl koroner ak›m olan hastalar aras›nda kan flekeri, kan bas›nçlar›, lipid deerleri ve vücut kitle indeks- leri aç›s›ndan anlaml› farkl›l›k bulunmufltur. Bu farkl›l›klar flansa bal› olabilecei gibi hastal›kla da iliflkili olabileceinden KYA ile intima-me- dia kal›nl›¤› aras›ndaki iliflkiye dair bir yarg›ya var›lmadan önce; bu efl-
Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology
To identify characteristics associated with complications during pregnancy in patients with mitra... more To identify characteristics associated with complications during pregnancy in patients with mitral stenosis. Thirty-seven pregnant women with mitral stenosis, followed-up from 1998 to 2001 were evaluated. Predictor variables were the mitral valve area (MVA) measured by echocardiogram and functional class (FC) before pregnancy according to NYHA criteria. Progression of functional class, thromboembolism, death, need in medical abortion, cardiac surgery or balloon mitral valvulotomy were accepted as maternal events. Fetal/neonatal events were determined as abortion, fetal or neonatal death, prematurity or low birth weight (p<2.500 g), and extended stay in the nursery or hospitalization in newborn intensive care unit. The mean +/- SD of age of the patients was 24.7+/-5.8 years. The eventful and uneventful patients were similar in age and percentage of first pregnancies. Of patients with an events occuring during gestational period, 37. 5% had class I functional capacity whereas 62.5%...
The Journal of invasive cardiology
Systemic embolization complicating intracoronary stenting before deployment is a rare complicatio... more Systemic embolization complicating intracoronary stenting before deployment is a rare complication; although it was not associated with any clinical sequelae, great care should be taken to prevent this possibility. We report a case of the successful retrieval of an embolized stent from the left ventricle during percutaneous transluminal coronary angioplasty of a left anterior descending coronary artery.
OBJECTIVES: Percutaneous coronary intervention of left main coronary artery (LMCA) in the setting... more OBJECTIVES: Percutaneous coronary intervention of left main coronary artery (LMCA) in the setting of acute myocardial infarction or in patients with cardiac and non-cardiac diseases that increase mortality rate after coronary artery bypass surgery has been proposed as "last resort option" and these patients can be managed safely with intracoronary stenting. In this study, we evaluated the short- and long-term follow-up outcomes of patients with left main coronary lesions underwent stent implantation in our clinic. METHOD: A total of 15 patients (12 M, 3 F; mean age 58 +/- 13 years) with left main coronary stenosis considered at high risk for surgical treatment or patients with acute myocardial infarction with LMCA stenosis were enrolled into the study and treated by stenting. Eight patients were treated for unstable angina (53%), 2 had stable angina (13%) and 5 had acute myocardial infarction (33%). Three patients had "protected" and 12 patients "unprotected...
Background: The mechanisms of the different hemodynamic and clinical responses to dobutamine infu... more Background: The mechanisms of the different hemodynamic and clinical responses to dobutamine infusion in mitral stenosis are not clearly established. The aim of this study was to evaluate the changing hemodynamic parameters in patiens with mitral stenosis that correlates with dyspnea during dobutamine infusion using Doppler echocardiography and to assess determinants of pulmonary artery pressure response. Methods and Results: Fifty-seven consecutive asymptomatic or mildly symptomatic patient (51 women, 6 men; mean age 43±7, range from 26 to 52), New York Heart Association (NYHA) class I (n: 9), class II (n: 48) with mitral stenosis (mean mitral valve area 1.6±0.4 cm 2) were evaluated with dobutamine stress echocardiography. Dyspnea developed during dobutamine infusion in 18 patients (Group B), but the other 39 patients remained asymptomatic (group A). There was a significantly greater increment in mitral peak gradient (14±7 vs 9±4 mmHg, p=0.008), mean gradient (12±6 vs 6±3 mmHg, p&l...
Turk Kardiyoloji Dernegi arsivi: Turk Kardiyoloji Derneginin yayin organidir
Objectives: Systemic inflammation plays an important role in the pathogenesis of atherosclerosis ... more Objectives: Systemic inflammation plays an important role in the pathogenesis of atherosclerosis in psoriasis patients. Therefore, persistent skin inflammation in psoriasis patients may contribute to the development of premature atherosclerosis, as it occurs in rheumatoid arthritis and systemic lupus erythematosus. We aimed to evaluate the relationship between subclinical atherosclerosis and psoriasis by using pulse wave velocity (PWV) and the measurement of carotid intima media thickness (CIMT) in psoriatic patients. Study design: Fifty-seven plaque-type psoriasis patients (31 males, 26 females; mean age 41±10.8 years) and 60 healthy individuals (32 males, 28 females; mean age 40±9.4 years) were included. Atherosclerotic risk factors were excluded in both of the groups. Demographic, bio-chemical data, psoriasis area and severity index (PASI) score of the psoriasis group, and disease duration were recorded. Carotid-femoral artery PWV and CIMT values were compared. Results: PWV, and ...
![Research paper thumbnail of [E-learning and problem based learning integration in cardiology education]](https://attachments.academia-assets.com/41202512/thumbnails/1.jpg)
](Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology
The aim of this study was to determine students' satisfaction with an e-learning environment ... more The aim of this study was to determine students' satisfaction with an e-learning environment which is developed to support classical problem-based learning (PBL) in medical education and its effect on academic achievement. In this cross-sectional study, students were provided with a web-based learning environment including learning materials related to objectives of the subject of PBL module, which could be used during independent study period. The study group comprised of all of the second year students (164 students) of Akdeniz University, Medical Faculty, during 2007-2008 education period. In order to gather data about students' satisfaction with learning environment, a questionnaire was administered to the students. Comparison of students' academic achievement was based on their performance score in PBL exam. Statistical analyses were performed using unpaired t test and Mann Whitney U test. Findings indicated that 72.6% of the students used e-learning practice. There...
![Research paper thumbnail of [E-learning in cardiology education]](https://attachments.academia-assets.com/41202462/thumbnails/1.jpg)
](Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology
Sıçanda doksorubisinin oluşturduğu fonksiyon bozukluğunun resveratrol ile düzelmesi Murat Olukman... more Sıçanda doksorubisinin oluşturduğu fonksiyon bozukluğunun resveratrol ile düzelmesi Murat Olukman et al.; İzmir, Türkiye Two estrogen receptor-α gene polymorphisms and coronary artery disease İki östrojen reseptör -α gen polimorfi zmi ve koroner arter hastalığı Bilgehan Karadağ et al.; İstanbul, Turkey, Bakersfi eld, CA, USA Ultrasonographic fatty liver, severity of coronary atherosclerosis, and obesity Koroner aterosklerozun şiddeti, karaciğer yağlanması ve obezite Mahmut Açıkel et al.; Erzurum, Türkiye Akut koroner sendromda yüksek duyarlı C-reaktif proteinin kestirim değeri Cut-off value of high sensitive C-reactive protein in acute coronary syndrome Teoman Kılıç ve ark.; Kocaeli, Türkiye Effects of nebivolol on P wave duration and dispersion in patients with slow coronary fl ow Koroner yavaş akımlı hastalarda nebivololün P dalga süresi ve dispersiyonuna etkileri Yılmaz Güneş et al.; Van, Türkiye Effects of antithyroid drugs on P wave changes in Graves disease Graves hastalarında antitiroid ilaçlar ve P dalga değişikliklerine etkileri Dilek Berker et al.; Ankara, Türkiye A population-based study on awareness of heart attack in Aydın city-Turkey Aydın-Türkiye'de kalp krizi farkındalığı üzerine toplum temelli bir çalışma Sakine Memiş et al.; Aydın, Türkiye Discrete supravalvar aortic stenosis in children Çoçuklarda diskret supravalvüler aort darlığı Ergin Koçyıldırım et al.; Ankara, Türkiye
Turk Kardiyoloji Dernegi arsivi: Turk Kardiyoloji Derneginin yayin organidir
In patients with Wolff-Parkinson-White syndrome, difficulty in ablation of accessory pathways is ... more In patients with Wolff-Parkinson-White syndrome, difficulty in ablation of accessory pathways is associated with failures and recurrences. Epicardially located accessory pathways may require different management strategies when conventional ablation attempts fail. In particular, an epicardial accessory pathway communicating the right atrial appendage to the right ventricle is an extraordinary situation resulting in difficulties in ablation. Hereby, we report on a challenging case of percutaneous epicardial ablation of an epicardial accessory pathway located at right atrial appendage in a 28-year-old man with Wolff-Parkinson-White syndrome, who had a prior history of unsuccessful endocardial ablation. Percutaneous epicardial ablation may be a viable option obviating the necessity of surgical ablation procedures for difficult ablation cases with epicardial accessory pathways.
The Turkish journal of gastroenterology: the official journal of Turkish Society of Gastroenterology
This study aimed to assess hemodynamic alterations noninvasively using a dedicated device Task Fo... more This study aimed to assess hemodynamic alterations noninvasively using a dedicated device Task Force® Monitor providing various hemodynamic data utilizing impedance cardiography and beat-to-beat blood pressure analysis via a vascular unloading unit. Forty-seven patients with cirrhosis awaiting hepatic transplantation and 26 healthy volunteers matched for age and gender were enrolled. Basic hemodynamic status of these patients (following temporary interruption of any drugs affecting the cardiovascular system) was evaluated noninvasively by Task Force® Monitor with patients in the supine position. Mean age of the patients was 46 years and 74.5% were male. The etiology of cirrhosis was viral hepatitis in 59.5% and alcoholic cirrhosis in 19.1% of cases, whereas 17% had cryptogenic cirrhosis. 38.3%, 25.5%, and 36.1% of the patients were stratified into groups A, B and C according to the Child-Pugh classification, respectively. Heart rate, cardiac output and cardiac index were significant...
Cardiology journal
Cocaine has become the most frequently used illicit drug among patients presenting to emergency d... more Cocaine has become the most frequently used illicit drug among patients presenting to emergency departments worldwide. Although acute myocardial infarction is the most common reported cardiovascular manifestation in this setting, there are many other potential cardiotoxic effects of cocaine use including coronary artery spasm, arrhythmia, and sudden death. We report the case of a 54 year-old male with angiographically documented reversible coronary arterial spasm leading to severe life-threatening recurrent ventricular arrhythmias and electrocardiographic changes suggesting acute myocardial infarction secondary to cocaine use. Recurrent ventricular arrhythmias of this patient required implantation of a cardioverter-defibrillator which successfully treated following arrhythmia episodes.
Kardiologia polska
During pregnancy heart rate, stroke volume, cardiac output and left ventricular (LV) mass increas... more During pregnancy heart rate, stroke volume, cardiac output and left ventricular (LV) mass increase while peripheral vascular resistance decreases. Gestational hypertension (GHT) which is noted in some pregnancies during the third trimester, is considered a temporary condition. Its effects on LV geometry are not known. To assess the effects of acute pressure overload in GHT on the LV geometry. Forty three pregnant women (mean age 28.7+/-8.9 years) with GHT were included in the study (Group A). Blood pressure levels >140/90 mmHg were considered diagnostic for GHT. Fifty six pregnant women (mean age 25.7+/-5.7 years) with normal blood pressure formed the control group (Group B). Transthoracic echocardiography was performed in all subjects before delivery. LV end-systolic (ESD) and end-diastolic (EDD) diameters, LV septal and posterior wall thickness were measured, and LV mass index (MI) as well as relative wall thickness (RWT) were calculated using Devereux and Ganau formulas. LV ge...
The International Journal of Cardiovascular Imaging
Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2007
Say›n Editör, Derginizin son say›s›nda yay›nlanan say›n Dr. Ö. Avflar ve ark.'a ait "Ko... more Say›n Editör, Derginizin son say›s›nda yay›nlanan say›n Dr. Ö. Avflar ve ark.'a ait "Koroner yavafl ak›m ile karotis intima-media kal›nl›¤› aras›ndaki iliflki" bafll›kl› makaleyi (1) ilgi ve dikkatle okudum. Benzer hasta popülasyonu üzerine çal›flmakta olduumdan dolay› kendi çal›flma tasar›m›m ile k›- yaslama olana¤› bulduum bu çal›flmaya iliflkin akl›mda soru iflaretleri b›rakan noktalar› (benzer çal›flma yapacak araflt›r›c›lara da uyar›c› ve yol gösterici olaca¤›n› düflünerek) paylaflma ihtiyac› duydum. Öncelikle çal›flmada koroner yavafl ak›m› (KYA) belirlemek amac›yla kullan›lan Gibson'un TIMI kare say›s› yöntemi için at›fta bulunulan "8" nu- maral› kayna¤›n (2) at›fta bulunulan konuyla iliflkisiz olduu (muhtemel diz- gi veya bask› hatas› ?) dikkatimi çekti. Buradan hareketle literatürde TIMI kare say›s›n› ele alan çal›flmalar›n temel at›f kayna¤› olan Gibson'un oriji- nal makalesine (3) ulaflt›m. Bu makalede hiç infarktüs geçirmemifl ve epi- kardiyal koroner arter darl›¤› saptanmayan (yazarlar›n çal›flmas›nda nor- mal koroner anjiyografi olarak belirtilen gruba özdefl) hastalarda sol ön inen koroner arter (LAD), sirkumfleks arter (Cx), sakoroner arter (RCA) ve düzeltilmifl LAD ak›m› için bulunan TIMI kare say›lar› s›ras›yla flöyledir: 36.2±2.6 (LAD), 22.2±4.1 (Cx), 20.4±3.0 (RCA), 21.1±1.5 (dLAD). Yazarlar›n yöntemi incelendiinde Gibson' un referans deerlerinin "standart ortala- malar›n›n 2 kare fazlas›n›n" KYA kriteri olarak al›nd›¤› anlafl›lmaktad›r. Fa- kat yazarlar›n burada LAD için belirtmifl olduklar› referans deer 38 olup, Gibson'un orijinal makalesindekinden farkl›d›r (?). "Standart ortalama de- ¤erlerin 2 fazlas›" tan›m› ile yazarlar›n LAD, Cx ve RCA için belirttikleri 38, 30 ve 26 deerlerine ulafl›lamad›¤›n› gördü¤ümden bu tan›m›n bir "ifade hatas›" olduunu ve asl›nda Gibson'un bulduu "ortalama deerlerin 2 standart sapma üzerinde" olan TIMI kare deerlerinin (ortalama +(stan- dart sapma x 2 )) KYA kriteri olarak kabul edildiini varsayd›m. Böylece (küsuratlar yuvarlanmak suretiyle) Cx için (22+(4x2)) 30 ve RCA için (20+(3x2)) 26 deerlerinin nas›l elde edildiini saptad›m. Ancak bu yöntem- le yine de LAD'de KYA tan›s› için yazarlar›n belirledii 38 deerine ulafl- mak mümkün deildir (Çünkü (36+(2x2))= 40 olmal›yd›). Bu nedenle LAD için KYA kriterinin neden dier koroner arterler için önerilen yöntemden farkl› olduunu ve nas›l hesapland›¤›n› merak etmekteyim. Ayr›ca önemli bir nokta da at›fta bulunulan Gibson'un çal›flmas›n›n 'sineanjiyografi' dö- neminde yap›lm›fl olmas› ve bu görüntülerin 30 pencere/saniye h›zda kay- dedilmifl olduklar›d›r. Oysa yazarlar çal›flmada bilgisayar disklerine kayde- dilen say›sal görüntüler üzerinde inceleme yapm›fllard›r. Bilindii gibi bu tür say›sal anjiyografi cihazlar› 30 pencere/saniye h›z›n alt›nda bir h›zda (genellikle 15-25 pencere/saniye) kay›t yapmaktad›rlar. Bu nedenle yazar- lar›n inceledikleri görüntülerin kay›t h›z›n›n makalede mutlaka belirtilmesi gerekir. Çünkü farkl› kay›t h›zlar›nda yap›lan görüntüleme deerlerinin ay- n› kriterlere göre ele al›narak incelenmesi hatal› olacakt›r. Bu durumda bir karfl›laflt›rma yapmak tamamen imkans›z olmay›p, yazarlar›n kay›t h›zlar›- na göre bulduklar› TIMI kare say›s›n› 30 pencere/saniye h›zl› kay›da oran- layarak dönüfltürmek suretiyle karfl›laflt›rmalar› da mümkündür (4). Ayr›ca KYA ile karotis arter intima-medya kal›nl›¤› aras›ndaki iliflki- yi inceleyen bu çal›flmada normal ve yavafl koroner ak›m olan hastalar aras›nda kan flekeri, kan bas›nçlar›, lipid deerleri ve vücut kitle indeks- leri aç›s›ndan anlaml› farkl›l›k bulunmufltur. Bu farkl›l›klar flansa bal› olabilecei gibi hastal›kla da iliflkili olabileceinden KYA ile intima-me- dia kal›nl›¤› aras›ndaki iliflkiye dair bir yarg›ya var›lmadan önce; bu efl-
Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology
To identify characteristics associated with complications during pregnancy in patients with mitra... more To identify characteristics associated with complications during pregnancy in patients with mitral stenosis. Thirty-seven pregnant women with mitral stenosis, followed-up from 1998 to 2001 were evaluated. Predictor variables were the mitral valve area (MVA) measured by echocardiogram and functional class (FC) before pregnancy according to NYHA criteria. Progression of functional class, thromboembolism, death, need in medical abortion, cardiac surgery or balloon mitral valvulotomy were accepted as maternal events. Fetal/neonatal events were determined as abortion, fetal or neonatal death, prematurity or low birth weight (p<2.500 g), and extended stay in the nursery or hospitalization in newborn intensive care unit. The mean +/- SD of age of the patients was 24.7+/-5.8 years. The eventful and uneventful patients were similar in age and percentage of first pregnancies. Of patients with an events occuring during gestational period, 37. 5% had class I functional capacity whereas 62.5%...
The Journal of invasive cardiology
Systemic embolization complicating intracoronary stenting before deployment is a rare complicatio... more Systemic embolization complicating intracoronary stenting before deployment is a rare complication; although it was not associated with any clinical sequelae, great care should be taken to prevent this possibility. We report a case of the successful retrieval of an embolized stent from the left ventricle during percutaneous transluminal coronary angioplasty of a left anterior descending coronary artery.
OBJECTIVES: Percutaneous coronary intervention of left main coronary artery (LMCA) in the setting... more OBJECTIVES: Percutaneous coronary intervention of left main coronary artery (LMCA) in the setting of acute myocardial infarction or in patients with cardiac and non-cardiac diseases that increase mortality rate after coronary artery bypass surgery has been proposed as "last resort option" and these patients can be managed safely with intracoronary stenting. In this study, we evaluated the short- and long-term follow-up outcomes of patients with left main coronary lesions underwent stent implantation in our clinic. METHOD: A total of 15 patients (12 M, 3 F; mean age 58 +/- 13 years) with left main coronary stenosis considered at high risk for surgical treatment or patients with acute myocardial infarction with LMCA stenosis were enrolled into the study and treated by stenting. Eight patients were treated for unstable angina (53%), 2 had stable angina (13%) and 5 had acute myocardial infarction (33%). Three patients had "protected" and 12 patients "unprotected...
Background: The mechanisms of the different hemodynamic and clinical responses to dobutamine infu... more Background: The mechanisms of the different hemodynamic and clinical responses to dobutamine infusion in mitral stenosis are not clearly established. The aim of this study was to evaluate the changing hemodynamic parameters in patiens with mitral stenosis that correlates with dyspnea during dobutamine infusion using Doppler echocardiography and to assess determinants of pulmonary artery pressure response. Methods and Results: Fifty-seven consecutive asymptomatic or mildly symptomatic patient (51 women, 6 men; mean age 43±7, range from 26 to 52), New York Heart Association (NYHA) class I (n: 9), class II (n: 48) with mitral stenosis (mean mitral valve area 1.6±0.4 cm 2) were evaluated with dobutamine stress echocardiography. Dyspnea developed during dobutamine infusion in 18 patients (Group B), but the other 39 patients remained asymptomatic (group A). There was a significantly greater increment in mitral peak gradient (14±7 vs 9±4 mmHg, p=0.008), mean gradient (12±6 vs 6±3 mmHg, p&l...
Turk Kardiyoloji Dernegi arsivi: Turk Kardiyoloji Derneginin yayin organidir
Objectives: Systemic inflammation plays an important role in the pathogenesis of atherosclerosis ... more Objectives: Systemic inflammation plays an important role in the pathogenesis of atherosclerosis in psoriasis patients. Therefore, persistent skin inflammation in psoriasis patients may contribute to the development of premature atherosclerosis, as it occurs in rheumatoid arthritis and systemic lupus erythematosus. We aimed to evaluate the relationship between subclinical atherosclerosis and psoriasis by using pulse wave velocity (PWV) and the measurement of carotid intima media thickness (CIMT) in psoriatic patients. Study design: Fifty-seven plaque-type psoriasis patients (31 males, 26 females; mean age 41±10.8 years) and 60 healthy individuals (32 males, 28 females; mean age 40±9.4 years) were included. Atherosclerotic risk factors were excluded in both of the groups. Demographic, bio-chemical data, psoriasis area and severity index (PASI) score of the psoriasis group, and disease duration were recorded. Carotid-femoral artery PWV and CIMT values were compared. Results: PWV, and ...
Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology
The aim of this study was to determine students' satisfaction with an e-learning environment ... more The aim of this study was to determine students' satisfaction with an e-learning environment which is developed to support classical problem-based learning (PBL) in medical education and its effect on academic achievement. In this cross-sectional study, students were provided with a web-based learning environment including learning materials related to objectives of the subject of PBL module, which could be used during independent study period. The study group comprised of all of the second year students (164 students) of Akdeniz University, Medical Faculty, during 2007-2008 education period. In order to gather data about students' satisfaction with learning environment, a questionnaire was administered to the students. Comparison of students' academic achievement was based on their performance score in PBL exam. Statistical analyses were performed using unpaired t test and Mann Whitney U test. Findings indicated that 72.6% of the students used e-learning practice. There...
Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology
Sıçanda doksorubisinin oluşturduğu fonksiyon bozukluğunun resveratrol ile düzelmesi Murat Olukman... more Sıçanda doksorubisinin oluşturduğu fonksiyon bozukluğunun resveratrol ile düzelmesi Murat Olukman et al.; İzmir, Türkiye Two estrogen receptor-α gene polymorphisms and coronary artery disease İki östrojen reseptör -α gen polimorfi zmi ve koroner arter hastalığı Bilgehan Karadağ et al.; İstanbul, Turkey, Bakersfi eld, CA, USA Ultrasonographic fatty liver, severity of coronary atherosclerosis, and obesity Koroner aterosklerozun şiddeti, karaciğer yağlanması ve obezite Mahmut Açıkel et al.; Erzurum, Türkiye Akut koroner sendromda yüksek duyarlı C-reaktif proteinin kestirim değeri Cut-off value of high sensitive C-reactive protein in acute coronary syndrome Teoman Kılıç ve ark.; Kocaeli, Türkiye Effects of nebivolol on P wave duration and dispersion in patients with slow coronary fl ow Koroner yavaş akımlı hastalarda nebivololün P dalga süresi ve dispersiyonuna etkileri Yılmaz Güneş et al.; Van, Türkiye Effects of antithyroid drugs on P wave changes in Graves disease Graves hastalarında antitiroid ilaçlar ve P dalga değişikliklerine etkileri Dilek Berker et al.; Ankara, Türkiye A population-based study on awareness of heart attack in Aydın city-Turkey Aydın-Türkiye'de kalp krizi farkındalığı üzerine toplum temelli bir çalışma Sakine Memiş et al.; Aydın, Türkiye Discrete supravalvar aortic stenosis in children Çoçuklarda diskret supravalvüler aort darlığı Ergin Koçyıldırım et al.; Ankara, Türkiye
Turk Kardiyoloji Dernegi arsivi: Turk Kardiyoloji Derneginin yayin organidir
In patients with Wolff-Parkinson-White syndrome, difficulty in ablation of accessory pathways is ... more In patients with Wolff-Parkinson-White syndrome, difficulty in ablation of accessory pathways is associated with failures and recurrences. Epicardially located accessory pathways may require different management strategies when conventional ablation attempts fail. In particular, an epicardial accessory pathway communicating the right atrial appendage to the right ventricle is an extraordinary situation resulting in difficulties in ablation. Hereby, we report on a challenging case of percutaneous epicardial ablation of an epicardial accessory pathway located at right atrial appendage in a 28-year-old man with Wolff-Parkinson-White syndrome, who had a prior history of unsuccessful endocardial ablation. Percutaneous epicardial ablation may be a viable option obviating the necessity of surgical ablation procedures for difficult ablation cases with epicardial accessory pathways.
The Turkish journal of gastroenterology: the official journal of Turkish Society of Gastroenterology
This study aimed to assess hemodynamic alterations noninvasively using a dedicated device Task Fo... more This study aimed to assess hemodynamic alterations noninvasively using a dedicated device Task Force® Monitor providing various hemodynamic data utilizing impedance cardiography and beat-to-beat blood pressure analysis via a vascular unloading unit. Forty-seven patients with cirrhosis awaiting hepatic transplantation and 26 healthy volunteers matched for age and gender were enrolled. Basic hemodynamic status of these patients (following temporary interruption of any drugs affecting the cardiovascular system) was evaluated noninvasively by Task Force® Monitor with patients in the supine position. Mean age of the patients was 46 years and 74.5% were male. The etiology of cirrhosis was viral hepatitis in 59.5% and alcoholic cirrhosis in 19.1% of cases, whereas 17% had cryptogenic cirrhosis. 38.3%, 25.5%, and 36.1% of the patients were stratified into groups A, B and C according to the Child-Pugh classification, respectively. Heart rate, cardiac output and cardiac index were significant...
Cardiology journal
Cocaine has become the most frequently used illicit drug among patients presenting to emergency d... more Cocaine has become the most frequently used illicit drug among patients presenting to emergency departments worldwide. Although acute myocardial infarction is the most common reported cardiovascular manifestation in this setting, there are many other potential cardiotoxic effects of cocaine use including coronary artery spasm, arrhythmia, and sudden death. We report the case of a 54 year-old male with angiographically documented reversible coronary arterial spasm leading to severe life-threatening recurrent ventricular arrhythmias and electrocardiographic changes suggesting acute myocardial infarction secondary to cocaine use. Recurrent ventricular arrhythmias of this patient required implantation of a cardioverter-defibrillator which successfully treated following arrhythmia episodes.
Kardiologia polska
During pregnancy heart rate, stroke volume, cardiac output and left ventricular (LV) mass increas... more During pregnancy heart rate, stroke volume, cardiac output and left ventricular (LV) mass increase while peripheral vascular resistance decreases. Gestational hypertension (GHT) which is noted in some pregnancies during the third trimester, is considered a temporary condition. Its effects on LV geometry are not known. To assess the effects of acute pressure overload in GHT on the LV geometry. Forty three pregnant women (mean age 28.7+/-8.9 years) with GHT were included in the study (Group A). Blood pressure levels >140/90 mmHg were considered diagnostic for GHT. Fifty six pregnant women (mean age 25.7+/-5.7 years) with normal blood pressure formed the control group (Group B). Transthoracic echocardiography was performed in all subjects before delivery. LV end-systolic (ESD) and end-diastolic (EDD) diameters, LV septal and posterior wall thickness were measured, and LV mass index (MI) as well as relative wall thickness (RWT) were calculated using Devereux and Ganau formulas. LV ge...