Rahim Aliyev | Azerbaijan Medical University (original) (raw)
Papers by Rahim Aliyev
American Journal of Case Reports, Jul 27, 2017
Rare co-existance of disease or pathology Background: Whether creatine-kinase (CK) is elevated or... more Rare co-existance of disease or pathology Background: Whether creatine-kinase (CK) is elevated or not in chronic inflammatory demyelinating polyneuropathy (CIDP) and its variants is not comprehensively investigated. Case Report: We report the case of a 47-year-old male who developed weakness of the left lower leg and the right index finger at age 42 years. At age 44 years, paresthesias and dysesthesias of both lower legs and mild right lower leg weakness additionally developed. CK was recurrently elevated since age 42 years but paraprotein and anti-myelin-associated glycoprotein (MAG)-antibodies were negative. Nerve conduction studies at age 43 years showed an axonal and demyelinating lesion with conduction blocks. Cerebrospinal fluid (CSF) investigations revealed mild pleocytosis and elevated protein, which is why CIDP variant was diagnosed. Immunoglobulins were administered with success. Because of recurrent relapses, immunoglobulins were increased at age 45 years, resulting in stabilization. Currently, the patient is infusing immunoglobulins subcutaneously himself. Conclusions: CIDP variants may go along with CK elevation, an axonal lesion, pleocytosis, and asymmetry of the lesion. A vanishing effect of immunoglobulins over time may be characteristic of CIDP variants.
Milli nevrologiya jurnalı, Feb 21, 2019
Background. Referring physicians are valuable sources of information for radiologist to improve q... more Background. Referring physicians are valuable sources of information for radiologist to improve quality in radiology. In dif ferent healthcare systems neuroradiology has developed differently. Healthcare in Azerbaijan is developing and investments take place both in infrastructure and knowledge. Tools to compare healthcare in Azerbaijan and western countries can help to guide these improvements by providing detailed information about a specific field resulting in a more focused approach. Methods. A survey covering the field of neuroradiology was developed, with a variety of items including the availability of equipment, the contentment with the radiological report, the experience of the neurologist, and factors omitting neurological imaging. Data was collected both in Azerbaijan and the Netherlands. Results. In both countries most neurologist do not receive formal neuroradiology training. The data demonstrate a higher avail ability of advanced computed tomography (CT) and magnetic resonance imaging (MRI) machines in the Netherlands compared with Azerbaijan, and a higher experience with requesting imaging and case reading for the Dutch respondents. The financial situation of the patient can be a reason for Azerbaijan neurologists to omit imaging (due to the establishment of CT and MRI in most cases in specialized and private centers). Conclusion. The presented survey allows comparison of neuroradiological healthcare between countries in general, and iden tification of required preconditions to improve collaboration between neurologists and radiologists. A future lower financial threshold for imaging and a future increase in availability of PACS (picture archiving and communication system) will facili tate the improvement of neuroradiological skills of Azerbaijan neurologists. Both Dutch and Azerbaijan neurologists consider weekly clinical neuroradiological conferences together with radiologists useful to improve their skills.
Journal of the Neurological Sciences, Oct 1, 2017
Compared to healthy controls, in multivariate logistic regression models, IFN-β was strongly asso... more Compared to healthy controls, in multivariate logistic regression models, IFN-β was strongly associated with headache (OR 7.105, pb0.001), while IFN-β-naïve controls presented a less strong association (OR 2.263, pb0.05). Moreover, MIDAS score was higher in the IFN-β group (16.9±20.7 vs. 2.1±5.8, pb0.001), while no statistical difference was detected in the IFN-β-naïve group (2.2 ±4.4 vs. 2.1±5.8, p 0.974). Likewise, multivariate linear regressions showed a positive association of IFN-β with the MIDAS score (β=7.043, pb0.001). Conclusion: In RRMS patients, IFN-β is associated with higher odds and severity of headache compared to healthy controls, while IFN-βnaïve patients present higher odds for headache but no difference in headache severity.
Milli nevrologiya jurnalı, Dec 2, 2018
Brief Summary about Region. Guba-Khachmaz economic region is situated in northeast of Azerbaijan.... more Brief Summary about Region. Guba-Khachmaz economic region is situated in northeast of Azerbaijan. This region consists of Siyazan, Shabran, Guba, Gusar, and Khachmaz administrative regions. Overall area of the region is 7.66 thousand sq. km, accounting for 8.8% of country's area. This economic region is characterized with its unique landscape features. There are four sharply differing altitude zones within the region ranging from 26 meters to 4466 meters, which are plains, foothill, mid-mountaineous, and high mountaineous zones. Climate also changes depending on the altitude, as warm climatic conditions prevail in plains, whereas high mountaineous areas are characterized with cold-humid and cold climate [9]. Landscape peculiarities and climatic conditions resemble smaller model of the country. Based on the results of National Census of Azerbaijan Republic for 2009, total number of population in the region is 488,741 thousand, accounting for 5.48% of country's population. 33.99% of population (166,105 thousand persons) reside in urban areas, whereas remaining 66.01% (322,636 thousand persons) are settled in rural areas. The highest number of urban population is located in Siyazan (65.6%), with the highest number of rural population being concentrated in Guba (75.11%). 49.84% of population (243,575 thousand persons) consist of men and 50.16% (245,166 thousand persons) of women. Average density of population in Guba-Khachmaz economic region is 63.8 persons per square kilometer, which is lower than country average. Average population density in
Clinical Neurophysiology, Jun 1, 2014
A slow but steady increase in neurodegenerative disorders has been noted in recent decades. Degen... more A slow but steady increase in neurodegenerative disorders has been noted in recent decades. Degenerations in the nervous system are found in Alzheimer’s disease (AD), Parkinson’s disease (PD) and motor neuron disease (MND). In MND spinal neurons degenerate causing muscle atrophy invariably leading to death from respiratory failure. What is causing this degeneration? No consistent explanation has been presented despite intense scientific efforts. Some indications point toward metallotoxic etiologies. MND clusters have been observed in regions with elevated metal concentrations in water and soil. Several studies show increased MND frequency in certain occupations. MND-like conditions are found in animals and animal metal exposure experiments show specific spinal cord accumulations of metals. To address possible metal contributions in MND causation we measured concentrations of 22 metals in cerebrospinal fluid (CSF) from 17 MND patients and 10 controls. Ethical approval was received. Statistically significantly increased concentrations were found for manganese (Mn), aluminum, cadmium, cobalt, copper, zinc, lead, vanadium and uranium (Table 1). Most of the detected metals are well known neurotoxicants. Manganese showed the most prominent differences between cases (median 5.67 mg/L) and controls (median 2.08 mg/L) (Fig. 1). Simultaneous sampling from plasma however did not show elevated concentrations, indicating metal accumulations in MND CSF. These data were presented in a thesis (http://hdl.handle.net/10616/41419) at the Karolinska Institutet Stockholm in May 2013. In AD and PD CSF metal data are scarce, but point towards metals as a contributing factor in disease causation. An overview covering
Parkinsonism & Related Disorders, 2012
Conclusions: There were no statistically significant correlation between IRLSSG rating scale scor... more Conclusions: There were no statistically significant correlation between IRLSSG rating scale score and depression, anxiety, ASEX scores. The cases were presented with scores of mild to moderate anxiety and depression. ASEX scores of RLS patients were higher in the study group. Limitations of this study, include relatively small number of participants and all patients had dopamine agonist treatment. Further studies with more patients who are not treated are needed to clarify the relationship between RLS and psychiatric, sexual disorders.
European Stroke Journal
Introduction: We assessed best available data on access and delivery of acute stroke unit (SU) ca... more Introduction: We assessed best available data on access and delivery of acute stroke unit (SU) care, intravenous thrombolysis (IVT) and endovascular treatment (EVT) in the European region in 2019 and 2020. Patients and methods: We compared national data per number of inhabitants and per 100 annual incident first-ever ischaemic strokes (AIIS) in 46 countries. Population estimates and ischaemic stroke incidence were based on United Nations data and the Global Burden of Disease Report 2019, respectively. Results: The estimated mean number of acute SUs in 2019 was 3.68 (95% CI: 2.90–4.45) per one million inhabitants (MIH) with 7/44 countries having less than one SU per one MIH. The estimated mean annual number of IVTs was 21.03 (95% CI: 15.63–26.43) per 100,000 and 17.14% (95% CI: 12.98–21.30) of the AIIS in 2019, with highest country rates at 79.19 and 52.66%, respectively, and 15 countries delivering less than 10 IVT per 100,000. The estimated mean annual number of EVTs in 2019 was 7....
NATIONAL JOURNAL OF NEUROLOGY, 2021
Təqdim edilmiş klinik hadisədə VogtKoyanagiHarada (VKH) sindromu və gövdənin birincili bədxassəli... more Təqdim edilmiş klinik hadisədə VogtKoyanagiHarada (VKH) sindromu və gövdənin birincili bədxassəli melanoması ilə, və şişin ümumi proqressivləşməsi ilə təzahür edən, nevroloji simptomları olmayan, MRT müayinədə yeni kontrast qəbul edən kəllədaxili ocaqları olan 65 yaşlı xəstə təsvir edilir. Sistem melanoma xəstəliyi fonunda, VKH kəllədaxili təzahürü kimi, beyin zədələnmələrinin düzgün radioloji interpretasiyası xəstənin, beyinin lüzumsuz bütövlükdə radioterapiyadan qorunması üçün mütləq olmuşdur.
NATIONAL JOURNAL OF NEUROLOGY, 2019
In 2015, the World Health Organization announced its Sustainable Development Goals. This agenda c... more In 2015, the World Health Organization announced its Sustainable Development Goals. This agenda contributes to reducing inequity in healthcare and improving health. In a world with major differences between countries, the following question should be asked: How can healthcare professionals in general (and radiologists in particular) from highincome countries (HIC) and lowand middleincome countries (LMIC) work together to improve global health? The purpose of this paper is to evaluate several recent crosscultural educational efforts in radiology in Azerbaijan and to formulate practical recommendations for radiology education and medical education in general carried out in LMICs by volunteers from HICs. Methods. From a series of four consecutive education projects, we analyzed the evaluation forms of two of the sessions. Furthermore, we evaluated all four education projects by systematic comparison and reflection on 21 items in the categories Background Information, People, and Practi...
NATIONAL JOURNAL OF NEUROLOGY, 2019
The research objective consisted in studying 10 year (1999-2008) dynamics of mortality and lethal... more The research objective consisted in studying 10 year (1999-2008) dynamics of mortality and lethality rates of stroke in the Guba-Khachmaz region. This region is located in the north-east of Azerbaijan. The population is 488,741, which is 5.48% of the total country population. 33.99% of population (166,105 person) live in sities, 66.01% (322,636 person) in rural regions. The most of urban population (65.6%) lives in Siyazan region, rural population (75.11%) in Guba region. 49.84% of the population is men and 50.16% is women. All cases of incidence and mortality from stroke in the region have been retrospectively studied from the data of Central Region Hospitals. According to the statistical work, in relation to the statistics indicating qualitative signs, level of mortality falling to 1000 people has been counted.
NATIONAL JOURNAL OF NEUROLOGY, 2018
The ame of this study was exploring age as risk factor for stroke among 173 stroke cases which r... more The ame of this study was exploring age as risk factor for stroke among 173 stroke cases which registered during 3 years (01.01.2007-31.12.2009) in Siyazan region of Azerbaijan. Mean age of stroke cases during investigated years was 65.2±0.9. Males had stroke at a younger age – 62.2±1.3 than females – 68.2±1.2 (p<0.001). Patients residing in rural areas had stroke at older age than urban population, which was at a statistically significant level. Most of the stroke patients fell into the age groups of 50-59 and 70-79. In first age group men, in second women. Mean age for ischaemic and hemorrhagic stroke cases was 65.8±0.9 and 57.6±3.4, respectively.
The Journal of Headache and Pain, 2014
Romanian Journal of Ophthalmology, 2019
Journal of Parkinson's Disease
Background: Little information is available on the official postgraduate and subspecialty trainin... more Background: Little information is available on the official postgraduate and subspecialty training programs in movement disorders (MD) in Europe and North Africa. Objective: To survey the accessible MD clinical training in these regions. Methods: We designed a survey on clinical training in MD in different medical fields, at postgraduate and specialized levels. We assessed the characteristics of the participants and the facilities for MD care in their respective countries. We examined whether there are structured, or even accredited postgraduate, or subspecialty MD training programs in neurology, neurosurgery, internal medicine, geriatrics, neuroradiology, neuropediatrics, and general practice. Participants also shared their suggestions and needs. Results: The survey was completed in 31/49 countries. Structured postgraduate MD programs in neurology exist in 20 countries; structured neurology subspecialty training exists in 14 countries and is being developed in two additional countr...
Clinical Case Reports
Topically applied betamethasone for actinic keratosis may trigger systemic side effects. Systemic... more Topically applied betamethasone for actinic keratosis may trigger systemic side effects. Systemic side effects of topical betamethasone may completely resolve after discontinuation of the causative agent. A 59‐year‐old male patient with scalp actinic keratosis developed fatigue and the need to sleep shortly after starting topical betamethasone/diclofenac ointment. Additionally, he experienced vertigo, nausea, sleep disturbance, change in character and recognition, tiredness, visual impairment, and elevated blood pressure. Since all symptoms resolved completely within 48 hours after discontinuation of the ointment, they were attributed to glucocorticoids.
F1000Research
In a recent article by Yim et al., a 15-month-old male is described who experienced severe rhabdo... more In a recent article by Yim et al., a 15-month-old male is described who experienced severe rhabdomyolysis with a creatine-kinase value (CKV) of 127494 U/l one day after intramuscular injection of an unidentified drug by the general practitioner. Rhabdomyolysis was not attributed to this injected drug but to compound heterozygous variants in LPIN1. The study has a number of shortcomings. Triggers of rhabdomyolysis should be unequivocally identified, a more extensive family history should be taken, and previous CKVs should be provided. Functional and biochemical tests should be carried out to confirm or exclude pathogenicity of the LPIN1 variants.
Molecular Genetics and Metabolism Reports
Translational Vision Science & Technology
romanian journal of ophthalmology
American Journal of Case Reports, Jul 27, 2017
Rare co-existance of disease or pathology Background: Whether creatine-kinase (CK) is elevated or... more Rare co-existance of disease or pathology Background: Whether creatine-kinase (CK) is elevated or not in chronic inflammatory demyelinating polyneuropathy (CIDP) and its variants is not comprehensively investigated. Case Report: We report the case of a 47-year-old male who developed weakness of the left lower leg and the right index finger at age 42 years. At age 44 years, paresthesias and dysesthesias of both lower legs and mild right lower leg weakness additionally developed. CK was recurrently elevated since age 42 years but paraprotein and anti-myelin-associated glycoprotein (MAG)-antibodies were negative. Nerve conduction studies at age 43 years showed an axonal and demyelinating lesion with conduction blocks. Cerebrospinal fluid (CSF) investigations revealed mild pleocytosis and elevated protein, which is why CIDP variant was diagnosed. Immunoglobulins were administered with success. Because of recurrent relapses, immunoglobulins were increased at age 45 years, resulting in stabilization. Currently, the patient is infusing immunoglobulins subcutaneously himself. Conclusions: CIDP variants may go along with CK elevation, an axonal lesion, pleocytosis, and asymmetry of the lesion. A vanishing effect of immunoglobulins over time may be characteristic of CIDP variants.
Milli nevrologiya jurnalı, Feb 21, 2019
Background. Referring physicians are valuable sources of information for radiologist to improve q... more Background. Referring physicians are valuable sources of information for radiologist to improve quality in radiology. In dif ferent healthcare systems neuroradiology has developed differently. Healthcare in Azerbaijan is developing and investments take place both in infrastructure and knowledge. Tools to compare healthcare in Azerbaijan and western countries can help to guide these improvements by providing detailed information about a specific field resulting in a more focused approach. Methods. A survey covering the field of neuroradiology was developed, with a variety of items including the availability of equipment, the contentment with the radiological report, the experience of the neurologist, and factors omitting neurological imaging. Data was collected both in Azerbaijan and the Netherlands. Results. In both countries most neurologist do not receive formal neuroradiology training. The data demonstrate a higher avail ability of advanced computed tomography (CT) and magnetic resonance imaging (MRI) machines in the Netherlands compared with Azerbaijan, and a higher experience with requesting imaging and case reading for the Dutch respondents. The financial situation of the patient can be a reason for Azerbaijan neurologists to omit imaging (due to the establishment of CT and MRI in most cases in specialized and private centers). Conclusion. The presented survey allows comparison of neuroradiological healthcare between countries in general, and iden tification of required preconditions to improve collaboration between neurologists and radiologists. A future lower financial threshold for imaging and a future increase in availability of PACS (picture archiving and communication system) will facili tate the improvement of neuroradiological skills of Azerbaijan neurologists. Both Dutch and Azerbaijan neurologists consider weekly clinical neuroradiological conferences together with radiologists useful to improve their skills.
Journal of the Neurological Sciences, Oct 1, 2017
Compared to healthy controls, in multivariate logistic regression models, IFN-β was strongly asso... more Compared to healthy controls, in multivariate logistic regression models, IFN-β was strongly associated with headache (OR 7.105, pb0.001), while IFN-β-naïve controls presented a less strong association (OR 2.263, pb0.05). Moreover, MIDAS score was higher in the IFN-β group (16.9±20.7 vs. 2.1±5.8, pb0.001), while no statistical difference was detected in the IFN-β-naïve group (2.2 ±4.4 vs. 2.1±5.8, p 0.974). Likewise, multivariate linear regressions showed a positive association of IFN-β with the MIDAS score (β=7.043, pb0.001). Conclusion: In RRMS patients, IFN-β is associated with higher odds and severity of headache compared to healthy controls, while IFN-βnaïve patients present higher odds for headache but no difference in headache severity.
Milli nevrologiya jurnalı, Dec 2, 2018
Brief Summary about Region. Guba-Khachmaz economic region is situated in northeast of Azerbaijan.... more Brief Summary about Region. Guba-Khachmaz economic region is situated in northeast of Azerbaijan. This region consists of Siyazan, Shabran, Guba, Gusar, and Khachmaz administrative regions. Overall area of the region is 7.66 thousand sq. km, accounting for 8.8% of country's area. This economic region is characterized with its unique landscape features. There are four sharply differing altitude zones within the region ranging from 26 meters to 4466 meters, which are plains, foothill, mid-mountaineous, and high mountaineous zones. Climate also changes depending on the altitude, as warm climatic conditions prevail in plains, whereas high mountaineous areas are characterized with cold-humid and cold climate [9]. Landscape peculiarities and climatic conditions resemble smaller model of the country. Based on the results of National Census of Azerbaijan Republic for 2009, total number of population in the region is 488,741 thousand, accounting for 5.48% of country's population. 33.99% of population (166,105 thousand persons) reside in urban areas, whereas remaining 66.01% (322,636 thousand persons) are settled in rural areas. The highest number of urban population is located in Siyazan (65.6%), with the highest number of rural population being concentrated in Guba (75.11%). 49.84% of population (243,575 thousand persons) consist of men and 50.16% (245,166 thousand persons) of women. Average density of population in Guba-Khachmaz economic region is 63.8 persons per square kilometer, which is lower than country average. Average population density in
Clinical Neurophysiology, Jun 1, 2014
A slow but steady increase in neurodegenerative disorders has been noted in recent decades. Degen... more A slow but steady increase in neurodegenerative disorders has been noted in recent decades. Degenerations in the nervous system are found in Alzheimer’s disease (AD), Parkinson’s disease (PD) and motor neuron disease (MND). In MND spinal neurons degenerate causing muscle atrophy invariably leading to death from respiratory failure. What is causing this degeneration? No consistent explanation has been presented despite intense scientific efforts. Some indications point toward metallotoxic etiologies. MND clusters have been observed in regions with elevated metal concentrations in water and soil. Several studies show increased MND frequency in certain occupations. MND-like conditions are found in animals and animal metal exposure experiments show specific spinal cord accumulations of metals. To address possible metal contributions in MND causation we measured concentrations of 22 metals in cerebrospinal fluid (CSF) from 17 MND patients and 10 controls. Ethical approval was received. Statistically significantly increased concentrations were found for manganese (Mn), aluminum, cadmium, cobalt, copper, zinc, lead, vanadium and uranium (Table 1). Most of the detected metals are well known neurotoxicants. Manganese showed the most prominent differences between cases (median 5.67 mg/L) and controls (median 2.08 mg/L) (Fig. 1). Simultaneous sampling from plasma however did not show elevated concentrations, indicating metal accumulations in MND CSF. These data were presented in a thesis (http://hdl.handle.net/10616/41419) at the Karolinska Institutet Stockholm in May 2013. In AD and PD CSF metal data are scarce, but point towards metals as a contributing factor in disease causation. An overview covering
Parkinsonism & Related Disorders, 2012
Conclusions: There were no statistically significant correlation between IRLSSG rating scale scor... more Conclusions: There were no statistically significant correlation between IRLSSG rating scale score and depression, anxiety, ASEX scores. The cases were presented with scores of mild to moderate anxiety and depression. ASEX scores of RLS patients were higher in the study group. Limitations of this study, include relatively small number of participants and all patients had dopamine agonist treatment. Further studies with more patients who are not treated are needed to clarify the relationship between RLS and psychiatric, sexual disorders.
European Stroke Journal
Introduction: We assessed best available data on access and delivery of acute stroke unit (SU) ca... more Introduction: We assessed best available data on access and delivery of acute stroke unit (SU) care, intravenous thrombolysis (IVT) and endovascular treatment (EVT) in the European region in 2019 and 2020. Patients and methods: We compared national data per number of inhabitants and per 100 annual incident first-ever ischaemic strokes (AIIS) in 46 countries. Population estimates and ischaemic stroke incidence were based on United Nations data and the Global Burden of Disease Report 2019, respectively. Results: The estimated mean number of acute SUs in 2019 was 3.68 (95% CI: 2.90–4.45) per one million inhabitants (MIH) with 7/44 countries having less than one SU per one MIH. The estimated mean annual number of IVTs was 21.03 (95% CI: 15.63–26.43) per 100,000 and 17.14% (95% CI: 12.98–21.30) of the AIIS in 2019, with highest country rates at 79.19 and 52.66%, respectively, and 15 countries delivering less than 10 IVT per 100,000. The estimated mean annual number of EVTs in 2019 was 7....
NATIONAL JOURNAL OF NEUROLOGY, 2021
Təqdim edilmiş klinik hadisədə VogtKoyanagiHarada (VKH) sindromu və gövdənin birincili bədxassəli... more Təqdim edilmiş klinik hadisədə VogtKoyanagiHarada (VKH) sindromu və gövdənin birincili bədxassəli melanoması ilə, və şişin ümumi proqressivləşməsi ilə təzahür edən, nevroloji simptomları olmayan, MRT müayinədə yeni kontrast qəbul edən kəllədaxili ocaqları olan 65 yaşlı xəstə təsvir edilir. Sistem melanoma xəstəliyi fonunda, VKH kəllədaxili təzahürü kimi, beyin zədələnmələrinin düzgün radioloji interpretasiyası xəstənin, beyinin lüzumsuz bütövlükdə radioterapiyadan qorunması üçün mütləq olmuşdur.
NATIONAL JOURNAL OF NEUROLOGY, 2019
In 2015, the World Health Organization announced its Sustainable Development Goals. This agenda c... more In 2015, the World Health Organization announced its Sustainable Development Goals. This agenda contributes to reducing inequity in healthcare and improving health. In a world with major differences between countries, the following question should be asked: How can healthcare professionals in general (and radiologists in particular) from highincome countries (HIC) and lowand middleincome countries (LMIC) work together to improve global health? The purpose of this paper is to evaluate several recent crosscultural educational efforts in radiology in Azerbaijan and to formulate practical recommendations for radiology education and medical education in general carried out in LMICs by volunteers from HICs. Methods. From a series of four consecutive education projects, we analyzed the evaluation forms of two of the sessions. Furthermore, we evaluated all four education projects by systematic comparison and reflection on 21 items in the categories Background Information, People, and Practi...
NATIONAL JOURNAL OF NEUROLOGY, 2019
The research objective consisted in studying 10 year (1999-2008) dynamics of mortality and lethal... more The research objective consisted in studying 10 year (1999-2008) dynamics of mortality and lethality rates of stroke in the Guba-Khachmaz region. This region is located in the north-east of Azerbaijan. The population is 488,741, which is 5.48% of the total country population. 33.99% of population (166,105 person) live in sities, 66.01% (322,636 person) in rural regions. The most of urban population (65.6%) lives in Siyazan region, rural population (75.11%) in Guba region. 49.84% of the population is men and 50.16% is women. All cases of incidence and mortality from stroke in the region have been retrospectively studied from the data of Central Region Hospitals. According to the statistical work, in relation to the statistics indicating qualitative signs, level of mortality falling to 1000 people has been counted.
NATIONAL JOURNAL OF NEUROLOGY, 2018
The ame of this study was exploring age as risk factor for stroke among 173 stroke cases which r... more The ame of this study was exploring age as risk factor for stroke among 173 stroke cases which registered during 3 years (01.01.2007-31.12.2009) in Siyazan region of Azerbaijan. Mean age of stroke cases during investigated years was 65.2±0.9. Males had stroke at a younger age – 62.2±1.3 than females – 68.2±1.2 (p<0.001). Patients residing in rural areas had stroke at older age than urban population, which was at a statistically significant level. Most of the stroke patients fell into the age groups of 50-59 and 70-79. In first age group men, in second women. Mean age for ischaemic and hemorrhagic stroke cases was 65.8±0.9 and 57.6±3.4, respectively.
The Journal of Headache and Pain, 2014
Romanian Journal of Ophthalmology, 2019
Journal of Parkinson's Disease
Background: Little information is available on the official postgraduate and subspecialty trainin... more Background: Little information is available on the official postgraduate and subspecialty training programs in movement disorders (MD) in Europe and North Africa. Objective: To survey the accessible MD clinical training in these regions. Methods: We designed a survey on clinical training in MD in different medical fields, at postgraduate and specialized levels. We assessed the characteristics of the participants and the facilities for MD care in their respective countries. We examined whether there are structured, or even accredited postgraduate, or subspecialty MD training programs in neurology, neurosurgery, internal medicine, geriatrics, neuroradiology, neuropediatrics, and general practice. Participants also shared their suggestions and needs. Results: The survey was completed in 31/49 countries. Structured postgraduate MD programs in neurology exist in 20 countries; structured neurology subspecialty training exists in 14 countries and is being developed in two additional countr...
Clinical Case Reports
Topically applied betamethasone for actinic keratosis may trigger systemic side effects. Systemic... more Topically applied betamethasone for actinic keratosis may trigger systemic side effects. Systemic side effects of topical betamethasone may completely resolve after discontinuation of the causative agent. A 59‐year‐old male patient with scalp actinic keratosis developed fatigue and the need to sleep shortly after starting topical betamethasone/diclofenac ointment. Additionally, he experienced vertigo, nausea, sleep disturbance, change in character and recognition, tiredness, visual impairment, and elevated blood pressure. Since all symptoms resolved completely within 48 hours after discontinuation of the ointment, they were attributed to glucocorticoids.
F1000Research
In a recent article by Yim et al., a 15-month-old male is described who experienced severe rhabdo... more In a recent article by Yim et al., a 15-month-old male is described who experienced severe rhabdomyolysis with a creatine-kinase value (CKV) of 127494 U/l one day after intramuscular injection of an unidentified drug by the general practitioner. Rhabdomyolysis was not attributed to this injected drug but to compound heterozygous variants in LPIN1. The study has a number of shortcomings. Triggers of rhabdomyolysis should be unequivocally identified, a more extensive family history should be taken, and previous CKVs should be provided. Functional and biochemical tests should be carried out to confirm or exclude pathogenicity of the LPIN1 variants.
Molecular Genetics and Metabolism Reports
Translational Vision Science & Technology
romanian journal of ophthalmology