Nese Kirimer | Anadolu University (original) (raw)

Papers by Nese Kirimer

Turkish Journal of Pharmaceutical Sciences, 2015

T. minus L. is a complex species which has been divided into three varieties in Turkey. These are... more T. minus L. is a complex species which has been divided into three varieties in Turkey. These are var. minus, var. majus (Crantz) Crepin and var. microphyllum Boiss. In this study, stem and leaf anatomial features of the varieties were described, compared and some differences have been determined in between the varieties. In transverse sections of stems; the shape of stems, presence or absence of trichomes, the number of vascular bundles and in leaf sections; the structure of the mesophyll and the shape of the epidermal cells were identified as possible differential characters. We believe that our results were carried out to provide additional evidence for taxonomists and it can be help to separate of varieties.

Tetrodotoxin (TTX) and fatty acids contents of five specimens of Lagocephalus sceleratus collecte... more Tetrodotoxin (TTX) and fatty acids contents of five specimens of Lagocephalus sceleratus collected from Antalya on the Turkish Mediterranean coast were studied. TTX was determined by LC-MS/MS analysis in intestines, liver, ovary and muscle. Fatty acids were determined by GC/MS analyses. The oil content was not high (6%) but polyunsaturated n3 and n-6 ratios were high.

Journal of Essential Oil Bearing Plants, 2017

The GC-MS analyses of the essential oils of inflorescence of Phlomis pungens Willd. (Lamiaceae), ... more The GC-MS analyses of the essential oils of inflorescence of Phlomis pungens Willd. (Lamiaceae), collected from Galalti, Altiagach and Nakhchivan of Azerbaijan, led to the identification of 2 monoterpenes, 44 sesquiterpenes, 1 diterpene and 4 aliphatic acids constituents accounting for over 93.9, 94.1 and 95.2% of the total oils. In the same way the GC-MS analyses of the essential oils of leaves collected from three localities led to the identification of 2 monoterpenes, 37 sesquiterpenes, 1 diterpene and 4 aliphatic acid constituents, too which responsible for over 90.3, 92.4 and 94.8% of the total oils. Non surprisingly, the main constituents of inflorescence and leaves oil were sesquiterpenes (mainly non-oxygenated) and aliphatic acids which these findings are consistent with previous studies on Phlomis genus. Quantitative and qualitative differences were found among essential oils of inflorescence and leaves of the plants collected from different localities of Azerbaijan.

Turkish Journal of Chemistry, 2001

Water distilled essential oils from two varieties of Sideritis erythrantha: var. erythrantha} and... more Water distilled essential oils from two varieties of Sideritis erythrantha: var. erythrantha} and var. cedretorum, both endemic in Turkey, were analysed by GC/MS. The main components were characterized as a -pinene (16.3-19.5%) and sabinene (6.1- 10.4%) for var. erythrantha; myrcene (21.9-24.3%) and a -pinene (11.4- 12.4%) for var. cedretorum.

The genus Stachys L. (Lamiaceae) is represented in Turkey by 83 species and altogether 109 taxa. ... more The genus Stachys L. (Lamiaceae) is represented in Turkey by 83 species and altogether 109 taxa. The rate of endemism in Turkey is 43.4 with 33 species. Stachys. obliqua Waldst et Kit was collected in July, 2015 in Yarimca to Eskisehir. The essential oil from air-dried aerial parts was isolated by hydrodistillation using a Clevenger apparatus. Chemical composition of the oil was investigated using GC- FID and GC/MS techniques. In total, 97 compounds were identified making up 70.1% of the total volatile constituents. Hexadecanoic acid (10.1%), germacrene D (8.2%), hexahydrofarnesyl acetone (4.4%), β-bourbonene (2.1%) were found as main constituents in the oil

Journal of Essential Oil Research, 2016

Abstract Lemon balm (Melissa officinalis L.) of the Lamiaceae family is an aromatic plant and wid... more Abstract Lemon balm (Melissa officinalis L.) of the Lamiaceae family is an aromatic plant and widely used for medicinal purposes. This present study aimed to determine the compounds from volatiles of the plant using in vitro induced micropropagated shoots. The volatile components were isolated by microdistillation technique from this economically important M. officinalis seedlings. The main components were determined by GC/FID and GC/MS from herbage A and herbage B as geranial (43.4–44.8%), neral (26.8–30.3%), alloaromadendrene (8.5 and 1.6%), geranyl acetate (7.4 and 5.7%), 6-methyl-5-hepten-2-one (3.5 and 3.5%), and β-caryophyllene (3.1 and 2.3%), respectively. The results obtained are in correlation with the previous studies.

Phytotherapy Research, 1992

In Turkish folk medicine, Akea paUida L. (A.) and Tilia argentea Desf. ex DC have been used for v... more In Turkish folk medicine, Akea paUida L. (A.) and Tilia argentea Desf. ex DC have been used for various purposes, such as expectorant, sedative, diuretic, diaphoretic, sedative activities etc. Since some of the folkloric uses may be related to anti-stress (adaptogenic) activity, the effects of fresh infusions of A. pauida and T. argenlea on mouse swimming performance were investigated. On the basis of our findings, these two plants prolonged the swimming time, suggesting an antistress (adaptogenic) activity.

Journal of Essential Oil Research, 1998

Hydrodistilled essential oil from aerial parts of Marrubium anisodon (Lamiaceae) was analyzed by ... more Hydrodistilled essential oil from aerial parts of Marrubium anisodon (Lamiaceae) was analyzed by GC-FID and GC/MS. Thirty-nine components were characterized representing 87.9 % of the oil. (Z)--Farnesene (20.2 %), nonacosane (18.5%) and -caryophyllene (13.3 %) were the main constituents.

Journal of Chromatography a, 2006

Uludag Arıcılık Dergisi, 2005

Mersin Universitesi Tıp Fakultesi Lokman Hekim Tıp Tarihi Ve Folklorik Tıp Dergisi, Apr 5, 2014

Chemistry of Natural Compounds, 2014

The genus Anthemis (Asteraceae) is represented in Turkey by 50 species, 27 being endemic and comp... more The genus Anthemis (Asteraceae) is represented in Turkey by 50 species, 27 being endemic and comprising altogether 80 taxa. Two of the endemic species are Anthemis pestalozzae Boiss. and A. rosea Sm. subsp. carnea (Boiss.) Grierson. These dwarf species grow wild in the southwest regions of Turkey. A detailed botanical description of the studied two species can be found in Flora of Turkey [1]. Anthemis species are used as herbal tea and for food flavoring, as well as in cosmetics and the pharmaceutical industry. Their extracts, tinctures, salves, and tisanes are widely used as antispasmodic, anti-inflammatory, and antibacterial in Europe [2-4]. The occurrence of sesquiterpene lactones and flavonoids in various Anthemis species has been reported in previous works [5-10]. According to the literature, only the essential oils of A. aciphylla var. aciphylla Boiss. [11], A. aciphylla var. discoidea Boiss. [12], A. coelopoda var. bourgaei Boiss. [11], A. cretica L. ssp. argaea (Boiss. et Bal.) Grierson [13], A. cretica var. leucanthemoides (Boiss.) Grierson [14], A. cretica var. pontica (Willd.) Grierson [15], A. dipsacea Bornm. [16], A. marschalliana Willd. ssp. pectinata [13], A. pectinata Boiss. et Reut. var. pectinata [16], A. pseudacotula Boiss. [15, 16], A. wiedemanniana Fisch. et C. A. Mey. [17], and A. xylopoda O. Schwarz [18] have been studied so far. To the best of our knowledge, this is the first report on the chemistry of these species. We focused our study on the composition of the oils using simultaneous GC and GC-MS analysis. According to our results, the main constituents from the aerial parts of Anthemis pestalozzae were characterized as E-caryophyllene (26.3%), limonene (10.6%), caryophyllene oxide (5.7%), linalool (5.0%), tricosane (4.4%), and D-humulene (4.0%). E-Caryophyllene was also found to be a major constituent in previously studied essential oils of A. altissima [19] and A. cretica var. pontica [15]. The main constituents of the aerial parts of A. rosea subsp. carnea were sabinene (13.1%), borneol (9.0%), E-pinene (8.0%), E-caryophyllene (8.0%), and 1,8-cineole (7.1%). Sabinene was also found to be the major constituent in the previously studied essential oil of A. segetalis (19.5%) [20]. Plant Material. Samples were collected at the full flowering stage, A. pestalozzae at the Antalya, Doner Gazino road and A. rosea ssp. carnea at the Antalya, Alanya-Ermenek road, Sapak location in april 2007. Voucher specimens are stored at the Baser collection (1841 and 1840). Isolation of the Volatiles. The volatiles were obtained by microdistillation of the dried, ground plant materials (500 mg) using an Eppendorf MicroDistiller® with 10 mL distilled water per sample vial. The sample vial was heated to 108qC at a rate of 20qC/min and kept at this temperature for 90 min, then heated to 112qC at a rate of 20qC/min and kept at this temperature for 30 min. The sample was subjected to a final post-run for 2 min under the same conditions. The collecting vial, containing a solution of NaCl (2.5 g) and water (0.5 mL) plus n-hexane (350 PL) to trap volatile components, was cooled to-5qC during distillation. After the distillation was completed, the organic layer in the collection vial was separated and analyzed by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS), simultaneously. GC-MS Analysis. The GC-MS analysis was carried out with an Agilent 5975 GC-MSD system. Innowax FSC column (60 m u 0.25 mm, 0.25 Pm film thickness) was used with helium as carrier gas (0.8 mL/min). GC oven temperature was kept at 60qC for 10 min and programmed to 220qC at a rate of 4qC/min, and kept constant at 220qC for 10 min and then programmed to 240qC at a rate of 1qC/min. Split ratio was adjusted at 40:1. The injector temperature was set at 250qC. Mass spectra were recorded at 70 eV. Mass range was from m/z 35 to 450.

Journal of Chromatography B: Biomedical Sciences and Applications, 1985

... TN 38163 (USA) KENNETH R. ELLINGTON and GEORGE R. BREESE Biological Sciences Research Center,... more ... TN 38163 (USA) KENNETH R. ELLINGTON and GEORGE R. BREESE Biological Sciences Research Center, University of North Carolina, Chapel Hill, NC 27514 (USA) and CLINTON D. KILTS ... 19 YM Chan, SJ Soldin, JM Swanson, CM Deber, JJ Thiessen and S. Macleod, Clin ...

Natural product communications, 2010

Incubation of alpha-cedrol and caryophyllene oxide with Neurospora crassa afforded 12beta-hydroxy... more Incubation of alpha-cedrol and caryophyllene oxide with Neurospora crassa afforded 12beta-hydroxy cedrol, 10alpha-hydroxy cedrol, and 3beta-hydroxy cedrol, and 12beta-hydroxy caryophyllene oxide as major metabolites, respectively. The antibacterial and radical scavenging activities of the metabolites were evaluated in vitro using broth microdilution and bioauthographic techniques. However, no significant antibacterial and antioxidant activities were observed when compared with those of standard substances.