Kenan Ateş | Ankara University (original) (raw)
Papers by Kenan Ateş
Abdominal Imaging, 2005
Background We evaluated the usefulness of magnetic resonance (MR) peritoneography for the examina... more Background We evaluated the usefulness of magnetic resonance (MR) peritoneography for the examination of complications from continuous ambulatory peritoneal dialysis (CAPD). Methods MR peritoneography was performed in 20 patients who had suspected CAPD-related complications. Patients who had active peritonitis were not included in the study. Before MR imaging, a mixture of 2000 mL of peritoneal dialysis solution and 20 mL of gadopentetate dimeglumine was instilled into the peritoneal cavity. MR imaging was performed on a 1.0-Tesla system using a body coil. Axial, coronal, and sagittal fat-saturated fast spoiled gradient echo (repetition/echo times, 100/6.3 ms; flip angle, 90 degrees), axial fat-saturated T2-weighted fast spin echo (repetition/echo times, 6000/107 ms), and coronal fat-saturated T2-weighted fast spin echo (repetition/echo times, 3000/96.2 ms) images of the abdomen and the pelvis were obtained. After drain-age, triplanar fat-saturated fast spoiled gradient echo images were repeated with the same parameters. Results Homogeneous distribution of the dialysate in the peritoneal cavity was detected in 18 patients (90%). In 12 patients (60%), fluid leaks were discovered peripheral to the exit site, tunnel, and site of peritoneal entrance of the catheter. Fluid leaks through the abdominal wall in five patients (25%), retroperitoneum in one patient (5%), and a previous operation site in one patient (5%) were demonstrated. No abnormal finding was detected in three patients (15%) who had clinically suspected complications, whereas a dialysate leak was found in two patients (10%) who had no significant finding at physical examination. Conclusions MR peritoneography provides detailed information about the anatomic distribution of dialysate leaks in patients treated with CAPD and poses no risks associated with ionizing radiation and nephrotoxic contrast medium.
Background: Several recent studies reported that a high baseline serum C-reactive protein (CRP) i... more Background: Several recent studies reported that a high baseline serum C-reactive protein (CRP) is a powerful predictor of mortality in dialysis patients. However, the acutephase response is intermittent and not a continuous feature in an individual patient. The aim of this prospective study was to determine whether serial analysis of serum CRP during follow-up allows better prediction of mortality and echocardiographic cardiac disease than a single baseline measurement in peritoneal dialysis (PD) patients. ♦♦ ♦♦ ♦ Methods: 97 PD patients were monitored for 3 years from the beginning of the treatment. We evaluated the effect of demographic features, comorbidity, blood pressure, blood biochemistry, including CRP, residual renal function, and indices of dialysis adequacy, on mortality and left ventricular hypertrophy (LVH). Cox regression analysis using both the baseline and the averaged values of the study parameters was carried out to determine factors predicting mortality. Logistic regression analysis was performed to determine which factors were independently predictive for LVH and the type of time course of serum CRP. ♦♦ ♦♦ ♦ Results: Baseline serum CRP was elevated in 29 patients (29.9%). While serum CRP exhibited a stable course (normal or high) in 55 patients (56.7%), it varied considerably over time in 42 patients (43.2%). In the Cox models, both the averaged serum CRP and the type of variability of CRP were predictors of mortality. On the contrary, baseline CRP did not affect adjusted survival. The averaged CRP was also an independent factor affecting LVH, but baseline CRP was not. Age, comorbidity index, instilled dialysate glucose concentration, and Kt/V urea were independently associated with the type of time course of serum CRP. ♦♦ ♦♦ ♦ Conclusion: The averaged value of serum CRP is more predictive of prognosis compared to the baseline value in PD patients. Determining serum CRP on a regular basis may be helpful to detect early signs of tissue damage or asymptomatic inflammation. Perit Dial Int 2005; 25:256-268 www.PDIConnect.com KEY WORDS: End-stage renal disease; mortality; left ventricular hypertrophy; serum C-reactive protein (CRP); baseline CRP level; time-averaged CRP level.
Renal Failure, 2003
To determine the rate, risk factors and outcome of Tuberculous Peritonitis (TBP) in patients trea... more To determine the rate, risk factors and outcome of Tuberculous Peritonitis (TBP) in patients treated with continuous ambulatory peritoneal dialysis (CAPD) in our units. Retrospectively, we reviewed the medical data of all CAPD patients from 12 centers for TBP, covering the period between 1986 and December 2002. All patients were from 12 renal clinics at tertiary-care university hospitals. Ten cases of TBP were identified among the CAPD patients in our centers. There were five male and five female patients with a mean age of 37.2 years. None of the patients had tuberculosis history, 6 patients had predominance of PNL. One patient had coincidental bacterial peritonitis. Two patients were successfully treated without the removal of the Tenckhoff catheter. TBP in CAPD patients is a very rare complication. In contrast to predominance of lymphocytes in nonuremic patients with tuberculous peritonitis, CAPD patients with tuberculous peritonitis may have predominance of PNL on examination of the peritoneal fluid. Since TBP has high morbidity and mortality, early diagnosis and treatment of disease are extremely important for improving outcome.
American Journal of Kidney Diseases, 2000
Epidermolisis Bülloza (EB), herediter mekanobüllöz bir hastalık gurubudur. Stratifiye olmuş squam... more Epidermolisis Bülloza (EB), herediter mekanobüllöz bir hastalık gurubudur. Stratifiye olmuş squamöz epitel bazal membranmda dermal/epidermal ayrılma ile karakterizedir. Erişkinlerde görülen Epidermolizis büllöza Aquisita ise otoimmün büllöz bir hastalık olup, bu grup hastalarda IgG grubu anti-BM (ABM) antikorlarm varlığı gösterilmiştir (1).
American Journal of Kidney Diseases, 2000
Kidney International, 2001
Effect of fluid and sodium removal on mortality in peritoneal by many factors, including age, rac... more Effect of fluid and sodium removal on mortality in peritoneal by many factors, including age, race, the presence of dialysis patients. comorbid conditions such as diabetes mellitus and car-Background. Adequacy of peritoneal dialysis (PD) traditiondiovascular disease, nutritional status, serum albumin ally is assessed using Kt/V urea and total creatinine clearance level, small solute clearance, and peritoneal membrane (TCC). However, this approach underestimates the importance transport property [5-15]. of fluid and sodium removal. The aim of this study was to determine the effect of fluid and sodium removal on morbidity Several groups have studied on the importance of and mortality in PD patients.
Epidermolisis Bülloza (EB), herediter mekanobüllöz bir hastalık gurubudur. Stratifiye olmuş squam... more Epidermolisis Bülloza (EB), herediter mekanobüllöz bir hastalık gurubudur. Stratifiye olmuş squamöz epitel bazal membranmda dermal/epidermal ayrılma ile karakterizedir. Erişkinlerde görülen Epidermolizis büllöza Aquisita ise otoimmün büllöz bir hastalık olup, bu grup hastalarda IgG grubu anti-BM (ABM) antikorlarm varlığı gösterilmiştir (1).
Kidney International, 2001
Effect of fluid and sodium removal on mortality in peritoneal by many factors, including age, rac... more Effect of fluid and sodium removal on mortality in peritoneal by many factors, including age, race, the presence of dialysis patients. comorbid conditions such as diabetes mellitus and car-Background. Adequacy of peritoneal dialysis (PD) traditiondiovascular disease, nutritional status, serum albumin ally is assessed using Kt/V urea and total creatinine clearance level, small solute clearance, and peritoneal membrane (TCC). However, this approach underestimates the importance transport property [5-15]. of fluid and sodium removal. The aim of this study was to determine the effect of fluid and sodium removal on morbidity Several groups have studied on the importance of and mortality in PD patients.
Abdominal Imaging, 2005
Background We evaluated the usefulness of magnetic resonance (MR) peritoneography for the examina... more Background We evaluated the usefulness of magnetic resonance (MR) peritoneography for the examination of complications from continuous ambulatory peritoneal dialysis (CAPD). Methods MR peritoneography was performed in 20 patients who had suspected CAPD-related complications. Patients who had active peritonitis were not included in the study. Before MR imaging, a mixture of 2000 mL of peritoneal dialysis solution and 20 mL of gadopentetate dimeglumine was instilled into the peritoneal cavity. MR imaging was performed on a 1.0-Tesla system using a body coil. Axial, coronal, and sagittal fat-saturated fast spoiled gradient echo (repetition/echo times, 100/6.3 ms; flip angle, 90 degrees), axial fat-saturated T2-weighted fast spin echo (repetition/echo times, 6000/107 ms), and coronal fat-saturated T2-weighted fast spin echo (repetition/echo times, 3000/96.2 ms) images of the abdomen and the pelvis were obtained. After drain-age, triplanar fat-saturated fast spoiled gradient echo images were repeated with the same parameters. Results Homogeneous distribution of the dialysate in the peritoneal cavity was detected in 18 patients (90%). In 12 patients (60%), fluid leaks were discovered peripheral to the exit site, tunnel, and site of peritoneal entrance of the catheter. Fluid leaks through the abdominal wall in five patients (25%), retroperitoneum in one patient (5%), and a previous operation site in one patient (5%) were demonstrated. No abnormal finding was detected in three patients (15%) who had clinically suspected complications, whereas a dialysate leak was found in two patients (10%) who had no significant finding at physical examination. Conclusions MR peritoneography provides detailed information about the anatomic distribution of dialysate leaks in patients treated with CAPD and poses no risks associated with ionizing radiation and nephrotoxic contrast medium.
Background: Several recent studies reported that a high baseline serum C-reactive protein (CRP) i... more Background: Several recent studies reported that a high baseline serum C-reactive protein (CRP) is a powerful predictor of mortality in dialysis patients. However, the acutephase response is intermittent and not a continuous feature in an individual patient. The aim of this prospective study was to determine whether serial analysis of serum CRP during follow-up allows better prediction of mortality and echocardiographic cardiac disease than a single baseline measurement in peritoneal dialysis (PD) patients. ♦♦ ♦♦ ♦ Methods: 97 PD patients were monitored for 3 years from the beginning of the treatment. We evaluated the effect of demographic features, comorbidity, blood pressure, blood biochemistry, including CRP, residual renal function, and indices of dialysis adequacy, on mortality and left ventricular hypertrophy (LVH). Cox regression analysis using both the baseline and the averaged values of the study parameters was carried out to determine factors predicting mortality. Logistic regression analysis was performed to determine which factors were independently predictive for LVH and the type of time course of serum CRP. ♦♦ ♦♦ ♦ Results: Baseline serum CRP was elevated in 29 patients (29.9%). While serum CRP exhibited a stable course (normal or high) in 55 patients (56.7%), it varied considerably over time in 42 patients (43.2%). In the Cox models, both the averaged serum CRP and the type of variability of CRP were predictors of mortality. On the contrary, baseline CRP did not affect adjusted survival. The averaged CRP was also an independent factor affecting LVH, but baseline CRP was not. Age, comorbidity index, instilled dialysate glucose concentration, and Kt/V urea were independently associated with the type of time course of serum CRP. ♦♦ ♦♦ ♦ Conclusion: The averaged value of serum CRP is more predictive of prognosis compared to the baseline value in PD patients. Determining serum CRP on a regular basis may be helpful to detect early signs of tissue damage or asymptomatic inflammation. Perit Dial Int 2005; 25:256-268 www.PDIConnect.com KEY WORDS: End-stage renal disease; mortality; left ventricular hypertrophy; serum C-reactive protein (CRP); baseline CRP level; time-averaged CRP level.
Renal Failure, 2003
To determine the rate, risk factors and outcome of Tuberculous Peritonitis (TBP) in patients trea... more To determine the rate, risk factors and outcome of Tuberculous Peritonitis (TBP) in patients treated with continuous ambulatory peritoneal dialysis (CAPD) in our units. Retrospectively, we reviewed the medical data of all CAPD patients from 12 centers for TBP, covering the period between 1986 and December 2002. All patients were from 12 renal clinics at tertiary-care university hospitals. Ten cases of TBP were identified among the CAPD patients in our centers. There were five male and five female patients with a mean age of 37.2 years. None of the patients had tuberculosis history, 6 patients had predominance of PNL. One patient had coincidental bacterial peritonitis. Two patients were successfully treated without the removal of the Tenckhoff catheter. TBP in CAPD patients is a very rare complication. In contrast to predominance of lymphocytes in nonuremic patients with tuberculous peritonitis, CAPD patients with tuberculous peritonitis may have predominance of PNL on examination of the peritoneal fluid. Since TBP has high morbidity and mortality, early diagnosis and treatment of disease are extremely important for improving outcome.
American Journal of Kidney Diseases, 2000
Epidermolisis Bülloza (EB), herediter mekanobüllöz bir hastalık gurubudur. Stratifiye olmuş squam... more Epidermolisis Bülloza (EB), herediter mekanobüllöz bir hastalık gurubudur. Stratifiye olmuş squamöz epitel bazal membranmda dermal/epidermal ayrılma ile karakterizedir. Erişkinlerde görülen Epidermolizis büllöza Aquisita ise otoimmün büllöz bir hastalık olup, bu grup hastalarda IgG grubu anti-BM (ABM) antikorlarm varlığı gösterilmiştir (1).
American Journal of Kidney Diseases, 2000
Kidney International, 2001
Effect of fluid and sodium removal on mortality in peritoneal by many factors, including age, rac... more Effect of fluid and sodium removal on mortality in peritoneal by many factors, including age, race, the presence of dialysis patients. comorbid conditions such as diabetes mellitus and car-Background. Adequacy of peritoneal dialysis (PD) traditiondiovascular disease, nutritional status, serum albumin ally is assessed using Kt/V urea and total creatinine clearance level, small solute clearance, and peritoneal membrane (TCC). However, this approach underestimates the importance transport property [5-15]. of fluid and sodium removal. The aim of this study was to determine the effect of fluid and sodium removal on morbidity Several groups have studied on the importance of and mortality in PD patients.
Epidermolisis Bülloza (EB), herediter mekanobüllöz bir hastalık gurubudur. Stratifiye olmuş squam... more Epidermolisis Bülloza (EB), herediter mekanobüllöz bir hastalık gurubudur. Stratifiye olmuş squamöz epitel bazal membranmda dermal/epidermal ayrılma ile karakterizedir. Erişkinlerde görülen Epidermolizis büllöza Aquisita ise otoimmün büllöz bir hastalık olup, bu grup hastalarda IgG grubu anti-BM (ABM) antikorlarm varlığı gösterilmiştir (1).
Kidney International, 2001
Effect of fluid and sodium removal on mortality in peritoneal by many factors, including age, rac... more Effect of fluid and sodium removal on mortality in peritoneal by many factors, including age, race, the presence of dialysis patients. comorbid conditions such as diabetes mellitus and car-Background. Adequacy of peritoneal dialysis (PD) traditiondiovascular disease, nutritional status, serum albumin ally is assessed using Kt/V urea and total creatinine clearance level, small solute clearance, and peritoneal membrane (TCC). However, this approach underestimates the importance transport property [5-15]. of fluid and sodium removal. The aim of this study was to determine the effect of fluid and sodium removal on morbidity Several groups have studied on the importance of and mortality in PD patients.