The Clinical Proteomic Technologies for Cancer (original) (raw)

Glutathione S-Transferase Mu1


Background

NCI Identification Number:

10541

Antigen Name:

Glutathione S-Transferase Mu1

CPTC Name:

CPTC-GST Mu1

Aliases:

GSTM1; EC 2.5.1.18; GST1; GSTM1-1; GSTM1a-1a; GSTM1b-1b; GTH4; GTM1; H-B; MGC26563; MU; MU-1; OTTHUMP00000013346; OTTHUMP00000013347

Function:

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles

Chromosomal Localization:

1p13.3

Expression System:

E. Coli

Accession Number:

J03817

UniProt Accession Number:

P09488

DNA Source:

HIP:HsCD00005373

Immunogen:

Recombinant Full Length Protein

Vector Name:

pMCSG7

Extinction Coefficient:

40005

Buffers:

50mM NH4HC03

Expressed Sequence:

SNAMPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWL
NEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRV
DILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPW
FAGNKITFVDFLVYDVLDLHRIFEPNCLDAFPNLKDFISRFEGLEKISAY
MKSSRFLPRPVFSKMAVWGNK

Native Sequence:

MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEK
FKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDIL
ENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAG
NKITFVDFLVYDVLDLHRIFEPNCLDAFPNLKDFISRFEGLEKISAYMKS
SRFLPRPVFSKMAVWGNK

Calculated Isoelectric Point:

6

Molecular Weight:

25970

Last Updated:

08/22/2020

Characterization Data

Gel

Click to enlarge image PAGE of Ag 10541 with molecular weight standards in lane 1.
Click image to enlarge

CPTC-GSTMu1

PAGE of Ag 10541 with molecular weight standards in lane 1.

SOPs

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