The Clinical Proteomic Technologies for Cancer (original) (raw)

Glutathione S-Transferase Mu2


Background

NCI Identification Number:

10112

Antigen Name:

Glutathione S-Transferase Mu2

CPTC Name:

CPTC-GST Mu2

Aliases:

GSTM2; EC 2.5.1.18; GST4; GSTM; GSTM2-2; GTHMUS; MGC117303; OTTHUMP00000013351

Function:

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles

Chromosomal Localization:

1p13.3

Expression System:

E. Coli

Accession Number:

NM_000848

UniProt Accession Number:

P28161

DNA Source:

HIP:HsCD00000624

Immunogen:

Recombinant Full Length Protein

Vector Name:

pMCSG7

Extinction Coefficient:

39943

Buffers:

50mM NH4HC03

Expressed Sequence:

SNAMPMTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWL
NEKFKLGLDFPNLPYLIDGTHKITQSNAILRYIARKHNLCGESEKEQIRE
DILENQFMDSRMQLAKLCYDPDFEKLKPEYLQALPEMLKLYSQFLGKQPW
FLGDKITFVDFIAYDVLERNQVFEPSCLDAFPNLKDFISRFEGLEKISAY
MKSSRFLPRPVFTKMAVWGNK

Native Sequence:

MPMTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEK
FKLGLDFPNLPYLIDGTHKITQSNAILRYIARKHNLCGESEKEQIREDIL
ENQFMDSRMQLAKLCYDPDFEKLKPEYLQALPEMLKLYSQFLGKQPWFLG
DKITFVDFIAYDVLERNQVFEPSCLDAFPNLKDFISRFEGLEKISAYMKS
SRFLPRPVFTKMAVWGNK

Calculated Isoelectric Point:

5.99

Molecular Weight:

26017

Last Updated:

08/22/2020

Characterization Data

Gel

Click to enlarge image PAGE of Ag 10112 (with molecular weight standards in lane 1)
Click image to enlarge

CPTC-GSTMu2

PAGE of Ag 10112 (with molecular weight standards in lane 1)

SOPs

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