Michael Moore | The Australian National University (original) (raw)

Papers by Michael Moore

2010 2nd International Workshop on Cognitive Information Processing, 2010

The highly cross-disciplinary emerging field of neuromorphic computing architectures for cognitiv... more The highly cross-disciplinary emerging field of neuromorphic computing architectures for cognitive information processing applications requires knowledge within many research fields: computer architecture, neuroscience, cognitive psychology, cognitive modeling, dynamical systems, belief systems, software, computer engineering, etc. In our effort to develop cognitive systems atop a neuromorphic computing architecture, we explored the issues associated with mapping computing strategies such as the Brain

The 2010 International Joint Conference on Neural Networks (IJCNN), 2010

Page 1. A Columnar Primary Visual Cortex (VI) Model Emulation Using a PS3 Cell-BE Array Michael J... more Page 1. A Columnar Primary Visual Cortex (VI) Model Emulation Using a PS3 Cell-BE Array Michael J. Moore, Richard Linderman, Fellow, IEEE Morgan Bishop, and Robinson Pino, Senior Member, IEEE Abstract-A model of ...

PloS one, 2013

Gas bubbles in marine mammals entangled and drowned in gillnets have been previously described by... more Gas bubbles in marine mammals entangled and drowned in gillnets have been previously described by computed tomography, gross examination and histopathology. The absence of bacteria or autolytic changes in the tissues of those animals suggested that the gas was produced peri- or post-mortem by a fast decompression, probably by quickly hauling animals entangled in the net at depth to the surface. Gas composition analysis and gas scoring are two new diagnostic tools available to distinguish gas embolisms from putrefaction gases. With this goal, these methods have been successfully applied to pathological studies of marine mammals. In this study, we characterized the flux and composition of the gas bubbles from bycaught marine mammals in anchored sink gillnets and bottom otter trawls. We compared these data with marine mammals stranded on Cape Cod, MA, USA. Fresh animals or with moderate decomposition (decomposition scores of 2 and 3) were prioritized. Results showed that bycaught anima...

2008 IEEE International Joint Conference on Neural Networks (IEEE World Congress on Computational Intelligence), 2008

Abstract Cogent confabulation is a computation model that mimics the Hebbian learning, informatio... more Abstract Cogent confabulation is a computation model that mimics the Hebbian learning, information storage, inter-relation of symbolic concepts, and the recall operations of the brain. The model has been applied to cognitive processing of language, audio and visual ...

Proceedings of the 9th International Conference on Interaction Design and Children - IDC '10, 2010

Biomaterials, 2006

As molecular, cellular, and tissue-level treatments for spinal cord injury are discovered, it is ... more As molecular, cellular, and tissue-level treatments for spinal cord injury are discovered, it is likely that combinations of such treatments will be necessary to elicit functional recovery in animal models or patients. We describe multiple-channel, biodegradable scaffolds that serve as the basis for a model to investigate simultaneously the effects on axon regeneration of scaffold architecture, transplanted cells, and locally delivered molecular agents. Poly(lactic-co-glycolic acid) (PLGA) with copolymer ratio 85:15 was used for these initial experiments. Injection molding with rapid solvent evaporation resulted in scaffolds with a plurality of distinct channels running parallel along the length of the scaffolds. The feasibility of creating scaffolds with various channel sizes and geometries was demonstrated. Walls separating open channels were found to possess void fractions as high as 89%, with accessible void fractions as high as 90% through connections 220 microm or larger. Scaf...

JAMA otolaryngology-- head & neck surgery, 2014

Head and neck cancer (HNC) is responsible for substantial morbidity, mortality, and cost in the U... more Head and neck cancer (HNC) is responsible for substantial morbidity, mortality, and cost in the United States. Early detection and lifestyle risk factors associated with HNC, both determinants of disease burden and outcomes, are interrelated with public knowledge of this disease. Understanding of current public knowledge of HNC is lacking. To assess awareness and knowledge of HNC among US adults. Online survey of 2126 randomly selected adults in the United States conducted in 2013. Online survey administration. Subjective and objective assessment of knowledge of HNC including symptoms, risk factors, and association with the human papillomavirus. Self-reported respondent knowledge of HNC was low, with 66.0% reporting that they were "not very" or "not at all" knowledgeable. This did not vary significantly with tobacco use (P = .92), education (P = .053), sex (P = .07), or race (P = .02). Regarding sites comprising HNC, 22.1% of respondents correctly identified thro...

Journal of Biomedical Materials Research, 2004

Integrative and Comparative Biology, 2008

Critical Reviews in Plant Sciences, 2009

Archives of Otolaryngology–Head & Neck Surgery, 2008

To investigate the use of the occipital rotational flap as an alternative reconstructive techniqu... more To investigate the use of the occipital rotational flap as an alternative reconstructive technique following lateral temporal bone resection. A retrospective medical record review of 10 patients who underwent reconstruction with an occipital rotational flap after auriculectomy or lateral temporal bone resection. Patient and operative variables included age, preoperative ASA (American Society of Anesthesiologists) classification, operative time, total length of hospital stay, and use of preoperative and postoperative radiotherapy. Patient demographic characteristics and medical comorbidities were also recorded. Clinical outcomes included medical complications, minor and major wound complications, and donor site complications. Patients' mean age was 73.9 years, and mean ASA classification was 2.8. The mean operative time was 8.1 hours, and the mean length of hospital stay was 5.3 days. Three patients received preoperative radiotherapy, and 7 received postoperative radiotherapy. Two patients developed postoperative medical complications, 2 developed minor wound breakdown, and 1 developed a donor site complication. The occipital flap method is reliable and should be considered as an option for reconstruction after lateral temporal bone resection in select patients.

The American Journal of the Medical Sciences, 2005

An aggressive global approach to screening and to the management of the metabolic syndrome is rec... more An aggressive global approach to screening and to the management of the metabolic syndrome is recommended to slow the growth of the syndrome throughout the United States. Prevention should begin in childhood with healthy nutrition, daily physical activity, and annual measurement of weight, height, and blood pressure beginning at 3 years of age. Such screenings will identify cardiovascular risk factors early, allow the health care provider to define global cardiovascular risk with the COSEHC Cardiovascular Risk Assessment Tool, and allow treatment of each risk factor. Lifelong lifestyle modifications and pharmacologic therapy will be required in most patients. Antihypertensive therapy for these patients should begin with an angiotensin-converting enzyme inhibitor or an angiotensin receptor blocker unless a compelling indication for another drug is present. Metformin should be considered the first drug for glucose control in the patient with type 2 diabetes. A statin should be used initially for hyperlipidemia unless contraindicated. Combinations of antihypertensive, antiglycemic, and lipid-lowering agents will often be required.

The American Journal of the Medical Sciences, 1999

The southeastern United States has the highest occurrence of heart disease and stroke and among t... more The southeastern United States has the highest occurrence of heart disease and stroke and among the highest rates of congestive heart failure and renal failure in the country. The Consortium for Southeastern Hypertension Control (COSEHC) is cooperating with other organizations in implementing initiatives to reduce morbidity and mortality from hypertension-related conditions in the southeastern United States. This article outlines for clinicians special consideration for implementation of the Sixth Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC VI) in the southeastern United States. Clinicians are encouraged to adapt the recommendations of JNC VI to their own patient groups, paying attention to these specific areas: (1) Ensure screening for hypertension in your practice and community. (2) Evaluate all patients for accompanying risk factors and target organ damage. (3) Promote lifestyle management for individual patients and populations for prevention and treatment of hypertension. (4) Set a goal blood pressure for each patient, and monitor progress toward that goal. (5) Recognize that many patients will be candidates for blood pressure goals of <130/85 mm Hg. (6) Pay attention to compelling and special indications such as diabetes, congestive heart failure, and renal dysfunction. (7) Consider combination therapy. (8) Maximize staff contributions to enhance patient adherence. (9) Encourage patient, family, and community activities to promote healthy lifestyles and blood pressure control.

The American Journal of the Medical Sciences, 1997

Stroke mortality is higher in the Southeast compared with other regions of the United States. The... more Stroke mortality is higher in the Southeast compared with other regions of the United States. The prevalence of hypertension is also higher (black men = 35%, black women = 37.7%, white men = 26.5%, white women = 21.5%), and the proportion of patients whose hypertension is being controlled is poor, especially in white and black men. The prevalence of hypertension-related complications other than stroke is also higher in the Southeast. The five states with the highest death rates for congestive heart failure are all in the southern region. Of the 15 states with the highest rates of end-stage renal disease, 10 are in the Southeast. Obesity is very prevalent (24% to 28%) in the Southeast. Although Michigan tops the ranking for all states, 6 of the top 15 states are in the Southeast, as are 7 of the 10 states with the highest reported prevalence regarding no leisure-time physical activity. Similar to other areas of the United States, dietary sodium and saturated fat intake are high in the Southeast; dietary potassium intake appears to be relatively low. Other factors that may be associated with the high prevalence, poor control, and excess morbidity and mortality of hypertension-related complications in the Southeast include misperceptions of the seriousness of the problem, the severity of the hypertension, lack of adequate follow-up, reduced access to health care, the cost of treatment, and possibly, low birth weights. The Consortium of Southeastern Hypertension Control (COSEHC) is a nonprofit organization created in 1992 in response to a compelling need to improve the disproportionate hypertension-related morbidity and mortality throughout this region. The purpose of this position paper is to summarize the data that document the problem, the consequences, and possible causative factors.

2010 2nd International Workshop on Cognitive Information Processing, 2010

The highly cross-disciplinary emerging field of neuromorphic computing architectures for cognitiv... more The highly cross-disciplinary emerging field of neuromorphic computing architectures for cognitive information processing applications requires knowledge within many research fields: computer architecture, neuroscience, cognitive psychology, cognitive modeling, dynamical systems, belief systems, software, computer engineering, etc. In our effort to develop cognitive systems atop a neuromorphic computing architecture, we explored the issues associated with mapping computing strategies such as the Brain

The 2010 International Joint Conference on Neural Networks (IJCNN), 2010

Page 1. A Columnar Primary Visual Cortex (VI) Model Emulation Using a PS3 Cell-BE Array Michael J... more Page 1. A Columnar Primary Visual Cortex (VI) Model Emulation Using a PS3 Cell-BE Array Michael J. Moore, Richard Linderman, Fellow, IEEE Morgan Bishop, and Robinson Pino, Senior Member, IEEE Abstract-A model of ...

PloS one, 2013

Gas bubbles in marine mammals entangled and drowned in gillnets have been previously described by... more Gas bubbles in marine mammals entangled and drowned in gillnets have been previously described by computed tomography, gross examination and histopathology. The absence of bacteria or autolytic changes in the tissues of those animals suggested that the gas was produced peri- or post-mortem by a fast decompression, probably by quickly hauling animals entangled in the net at depth to the surface. Gas composition analysis and gas scoring are two new diagnostic tools available to distinguish gas embolisms from putrefaction gases. With this goal, these methods have been successfully applied to pathological studies of marine mammals. In this study, we characterized the flux and composition of the gas bubbles from bycaught marine mammals in anchored sink gillnets and bottom otter trawls. We compared these data with marine mammals stranded on Cape Cod, MA, USA. Fresh animals or with moderate decomposition (decomposition scores of 2 and 3) were prioritized. Results showed that bycaught anima...

2008 IEEE International Joint Conference on Neural Networks (IEEE World Congress on Computational Intelligence), 2008

Abstract Cogent confabulation is a computation model that mimics the Hebbian learning, informatio... more Abstract Cogent confabulation is a computation model that mimics the Hebbian learning, information storage, inter-relation of symbolic concepts, and the recall operations of the brain. The model has been applied to cognitive processing of language, audio and visual ...

Proceedings of the 9th International Conference on Interaction Design and Children - IDC '10, 2010

Biomaterials, 2006

As molecular, cellular, and tissue-level treatments for spinal cord injury are discovered, it is ... more As molecular, cellular, and tissue-level treatments for spinal cord injury are discovered, it is likely that combinations of such treatments will be necessary to elicit functional recovery in animal models or patients. We describe multiple-channel, biodegradable scaffolds that serve as the basis for a model to investigate simultaneously the effects on axon regeneration of scaffold architecture, transplanted cells, and locally delivered molecular agents. Poly(lactic-co-glycolic acid) (PLGA) with copolymer ratio 85:15 was used for these initial experiments. Injection molding with rapid solvent evaporation resulted in scaffolds with a plurality of distinct channels running parallel along the length of the scaffolds. The feasibility of creating scaffolds with various channel sizes and geometries was demonstrated. Walls separating open channels were found to possess void fractions as high as 89%, with accessible void fractions as high as 90% through connections 220 microm or larger. Scaf...

JAMA otolaryngology-- head & neck surgery, 2014

Head and neck cancer (HNC) is responsible for substantial morbidity, mortality, and cost in the U... more Head and neck cancer (HNC) is responsible for substantial morbidity, mortality, and cost in the United States. Early detection and lifestyle risk factors associated with HNC, both determinants of disease burden and outcomes, are interrelated with public knowledge of this disease. Understanding of current public knowledge of HNC is lacking. To assess awareness and knowledge of HNC among US adults. Online survey of 2126 randomly selected adults in the United States conducted in 2013. Online survey administration. Subjective and objective assessment of knowledge of HNC including symptoms, risk factors, and association with the human papillomavirus. Self-reported respondent knowledge of HNC was low, with 66.0% reporting that they were "not very" or "not at all" knowledgeable. This did not vary significantly with tobacco use (P = .92), education (P = .053), sex (P = .07), or race (P = .02). Regarding sites comprising HNC, 22.1% of respondents correctly identified thro...

Journal of Biomedical Materials Research, 2004

Integrative and Comparative Biology, 2008

Critical Reviews in Plant Sciences, 2009

Archives of Otolaryngology–Head & Neck Surgery, 2008

To investigate the use of the occipital rotational flap as an alternative reconstructive techniqu... more To investigate the use of the occipital rotational flap as an alternative reconstructive technique following lateral temporal bone resection. A retrospective medical record review of 10 patients who underwent reconstruction with an occipital rotational flap after auriculectomy or lateral temporal bone resection. Patient and operative variables included age, preoperative ASA (American Society of Anesthesiologists) classification, operative time, total length of hospital stay, and use of preoperative and postoperative radiotherapy. Patient demographic characteristics and medical comorbidities were also recorded. Clinical outcomes included medical complications, minor and major wound complications, and donor site complications. Patients' mean age was 73.9 years, and mean ASA classification was 2.8. The mean operative time was 8.1 hours, and the mean length of hospital stay was 5.3 days. Three patients received preoperative radiotherapy, and 7 received postoperative radiotherapy. Two patients developed postoperative medical complications, 2 developed minor wound breakdown, and 1 developed a donor site complication. The occipital flap method is reliable and should be considered as an option for reconstruction after lateral temporal bone resection in select patients.

The American Journal of the Medical Sciences, 2005

An aggressive global approach to screening and to the management of the metabolic syndrome is rec... more An aggressive global approach to screening and to the management of the metabolic syndrome is recommended to slow the growth of the syndrome throughout the United States. Prevention should begin in childhood with healthy nutrition, daily physical activity, and annual measurement of weight, height, and blood pressure beginning at 3 years of age. Such screenings will identify cardiovascular risk factors early, allow the health care provider to define global cardiovascular risk with the COSEHC Cardiovascular Risk Assessment Tool, and allow treatment of each risk factor. Lifelong lifestyle modifications and pharmacologic therapy will be required in most patients. Antihypertensive therapy for these patients should begin with an angiotensin-converting enzyme inhibitor or an angiotensin receptor blocker unless a compelling indication for another drug is present. Metformin should be considered the first drug for glucose control in the patient with type 2 diabetes. A statin should be used initially for hyperlipidemia unless contraindicated. Combinations of antihypertensive, antiglycemic, and lipid-lowering agents will often be required.

The American Journal of the Medical Sciences, 1999

The southeastern United States has the highest occurrence of heart disease and stroke and among t... more The southeastern United States has the highest occurrence of heart disease and stroke and among the highest rates of congestive heart failure and renal failure in the country. The Consortium for Southeastern Hypertension Control (COSEHC) is cooperating with other organizations in implementing initiatives to reduce morbidity and mortality from hypertension-related conditions in the southeastern United States. This article outlines for clinicians special consideration for implementation of the Sixth Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC VI) in the southeastern United States. Clinicians are encouraged to adapt the recommendations of JNC VI to their own patient groups, paying attention to these specific areas: (1) Ensure screening for hypertension in your practice and community. (2) Evaluate all patients for accompanying risk factors and target organ damage. (3) Promote lifestyle management for individual patients and populations for prevention and treatment of hypertension. (4) Set a goal blood pressure for each patient, and monitor progress toward that goal. (5) Recognize that many patients will be candidates for blood pressure goals of <130/85 mm Hg. (6) Pay attention to compelling and special indications such as diabetes, congestive heart failure, and renal dysfunction. (7) Consider combination therapy. (8) Maximize staff contributions to enhance patient adherence. (9) Encourage patient, family, and community activities to promote healthy lifestyles and blood pressure control.

The American Journal of the Medical Sciences, 1997

Stroke mortality is higher in the Southeast compared with other regions of the United States. The... more Stroke mortality is higher in the Southeast compared with other regions of the United States. The prevalence of hypertension is also higher (black men = 35%, black women = 37.7%, white men = 26.5%, white women = 21.5%), and the proportion of patients whose hypertension is being controlled is poor, especially in white and black men. The prevalence of hypertension-related complications other than stroke is also higher in the Southeast. The five states with the highest death rates for congestive heart failure are all in the southern region. Of the 15 states with the highest rates of end-stage renal disease, 10 are in the Southeast. Obesity is very prevalent (24% to 28%) in the Southeast. Although Michigan tops the ranking for all states, 6 of the top 15 states are in the Southeast, as are 7 of the 10 states with the highest reported prevalence regarding no leisure-time physical activity. Similar to other areas of the United States, dietary sodium and saturated fat intake are high in the Southeast; dietary potassium intake appears to be relatively low. Other factors that may be associated with the high prevalence, poor control, and excess morbidity and mortality of hypertension-related complications in the Southeast include misperceptions of the seriousness of the problem, the severity of the hypertension, lack of adequate follow-up, reduced access to health care, the cost of treatment, and possibly, low birth weights. The Consortium of Southeastern Hypertension Control (COSEHC) is a nonprofit organization created in 1992 in response to a compelling need to improve the disproportionate hypertension-related morbidity and mortality throughout this region. The purpose of this position paper is to summarize the data that document the problem, the consequences, and possible causative factors.