ADAM17, CPTAC-1561 - CPTAC Assay Portal (original) (raw)
Official Gene Symbol
ADAM17
Peptide Sequence
VDNEELLPK
Modification Type
unmodified
Protein - Site of Modification
N/A
Peptide - Site of Modification
4
Peptide Start
189
Peptide End
197
CPTAC ID
CPTAC-5968
Peptide Molecular Mass
1,055.5499
Species
Homo sapiens (Human)
Assay Type
Enrichment MRM or SRM
Enrichment Method
N/A
Matrix
FFPE tumor tissue lysate pool
Submitting Laboratory
Fred Hutchinson Cancer Research Center
Submitting Lab PI
Amanda Paulovich
Publication
View Details (opens in a new window)
Targeted Mass Spectrometry Enables Multiplexed Quantification of Immunomodulatory Proteins in Clinical Biospecimens.Whiteaker JR, Lundeen RA, Zhao L, Schoenherr RM, Burian A, Huang D, Voytovich U, Wang T, Kennedy JJ, Ivey RG, Lin C, Murillo OD, Lorentzen TD, Thiagarajan M, Colantonio S, Caceres TW, Roberts RR, Knotts JG, Reading JJ, Kaczmarczyk JA, Richardson CW, Garcia-Buntley SS, Bocik W, Hewitt SM, Murray KE, Do N, Brophy M, Wilz SW, Yu H, Ajjarapu S, Boja E, Hiltke T, Rodriguez H, Paulovich AG.Front Immunol. 2021 Nov 11;12:765898. doi: 10.3389/fimmu.2021.765898. eCollection 2021.PMID: 34858420
| | Average intra-assay CV(within day CV) | Average inter-assay CV(between day CV) | Total CV
| n= | | | | | | | | | |
| ---------------------------------------- | -------------------------------------- | --------------------------------------------------------------------------------- | -------- | ------- | ------- | -------- | ------- | ------- | -------- | ------- | ------- | -------- |
| Fragment ion / Transition | Low | Med | High | Low | Med | High | Low | Med | High | Low | Med | High |
| y7 (1+) | 43.3 | 19 | 5.9 | 36.5 | 24.5 | 20.3 | 56.6 | 31 | 21.1 | 13 | 25 | 14 |
| y5 (1+) | 42.2 | 20.5 | 6.6 | 41.5 | 23 | 18.9 | 59.2 | 30.8 | 20 | 13 | 25 | 14 |
| y8 (1+) | 18.4 | 13.2 | 6.4 | 15.3 | 17 | 19.1 | 23.9 | 21.5 | 20.1 | 13 | 25 | 14 |
| sum | 20.6 | 9.7 | 4.8 | 21.7 | 15.8 | 19 | 29.9 | 18.5 | 19.6 | 13 | 25 | 14 |