Naomi Grey | The University of Auckland (original) (raw)
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Papers by Naomi Grey
Archives of Disease in Childhood, 2020
Objective To determine if administration of oral prednisolone to preschool children with acute wh... more Objective To determine if administration of oral prednisolone to preschool children with acute wheeze alters respiratory outcomes. Design Double-blind, randomised, placebo-controlled equivalence trial. Setting Three hospitals in New Zealand. Patients 477 children aged 24–59 months with acute wheeze associated with respiratory illness. Interventions 2 mg/kg (maximum 40 mg) oral prednisolone or similar placebo, once daily for 3 days. Main outcome measures Primary outcome was change in Preschool Respiratory Assessment Measure (PRAM) score 24 hours after intervention. Secondary outcomes included PRAM score at 4 hours, length of emergency department and inpatient stays, admission and representation rates, time to return to normal activities and use of additional oral prednisolone or intravenous medications. Analysis was by intention-to-treat. Results There was no difference between groups for change in PRAM score at 24 hours (difference between means −0.39, 95% CI −0.84 to 0.06, p=0.09)....
Paediatric Asthma and Allergy
Archives of Disease in Childhood, 2020
Objective To determine if administration of oral prednisolone to preschool children with acute wh... more Objective To determine if administration of oral prednisolone to preschool children with acute wheeze alters respiratory outcomes. Design Double-blind, randomised, placebo-controlled equivalence trial. Setting Three hospitals in New Zealand. Patients 477 children aged 24–59 months with acute wheeze associated with respiratory illness. Interventions 2 mg/kg (maximum 40 mg) oral prednisolone or similar placebo, once daily for 3 days. Main outcome measures Primary outcome was change in Preschool Respiratory Assessment Measure (PRAM) score 24 hours after intervention. Secondary outcomes included PRAM score at 4 hours, length of emergency department and inpatient stays, admission and representation rates, time to return to normal activities and use of additional oral prednisolone or intravenous medications. Analysis was by intention-to-treat. Results There was no difference between groups for change in PRAM score at 24 hours (difference between means −0.39, 95% CI −0.84 to 0.06, p=0.09)....
Paediatric Asthma and Allergy