Roland Glauser | Augusta University (original) (raw)

Papers by Roland Glauser

Research paper thumbnail of Early bone formation around immediately placed two-piece tissue-level zirconia implants with a modified surface: an experimental study in the miniature pig mandible

International Journal of Implant Dentistry

Purpose To histologically examine early bone formation around transmucosal implants and to evalua... more Purpose To histologically examine early bone formation around transmucosal implants and to evaluate the influence of surface characteristics on early peri-implant bone healing using a miniature pig model. For this, commercially available dental implants with a rough zirconia (YTZP) surface were compared to surface-modified Ti control implants at 4 and 8 weeks after placement. Methods Immediately following the extraction of six mandibular premolars, 20 two-piece, tissue-level, screw-shaped YTZP implants (Patent™ Standard Zirconia Implant ø4.1 × 11 mm) with a modified rough blasted before sintering surface were inserted in four adult miniature pigs. In addition, four titanium (Ti) tissue-level implants (Straumann® Standard RN ø4.1 × 10 mm Roxolid®) with a moderate surface (SLActive®), one per animal, were placed as control implants. A histological analysis was performed on the hard tissues after 4 and 8 weeks of transmucosal healing. Results The results show a high rate of osseointegr...

Research paper thumbnail of Al2O3 Particles on Titanium Dental Implant Systems following Sandblasting and Acid-Etching Process

International Journal of Biomaterials, 2019

Dental implants with moderately rough surfaces show enhanced osseointegration and faster bone hea... more Dental implants with moderately rough surfaces show enhanced osseointegration and faster bone healing compared with machined surfaces. The sandblasting and acid-etching (SA) process is one technique to create moderately rough dental implant surfaces. The purpose of this study was to analyse different commercially available implant systems with a SA-modified surface and to explore the widespread notion that they have similar surface properties regarding morphology and cleanliness. SA-modified surfaces of nine implant systems manufactured by Alpha-Bio Tec Ltd, Camlog Biotechnologies AG, Dentsply Sirona Dental GmbH, Neoss Ltd, Osstem Implant Co. Ltd, Institute Straumann AG, and Thommen Medical AG were analyzed using scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDX) and examined for surface cleanliness. Six implants from three different lots were selected per each implant system. Mean particle counts for each implant and the mean size of the particles wer...

Research paper thumbnail of Immediate occlusal loading of Brånemark System TiUnite implants placed predominantly in soft bone: 4-year results of a prospective clinical study

Clinical Implant Dentistry and Related Research, 2005

Immediate occlusal implant loading has been documented as a viable treatment option for various i... more Immediate occlusal implant loading has been documented as a viable treatment option for various indications. However, most of the available studies reported on the short-term outcome of this treatment modality. The purpose of this prospective clinical study was to document, on a long-term basis, the outcome of immediate occlusally loaded Brånemark System Mk IV TiUnite (Nobel Biocare AB, Göteborg, Sweden) implants placed to support fixed reconstructions in various regions of the jaws. Thirty-eight patients received a total of 51 fixed prosthetic reconstructions, all of which were connected on the day of implant insertion. Twenty restorations replaced single teeth, 30 were fixed partial dentures, and 1 was a full-arch fixed lower restoration. These prostheses were supported by 102 Brånemark System Mk IV TiUnite implants (38 maxillary and 64 mandibular), the majority of which were placed in posterior regions (88%) and mainly in soft bone (76%). Resonance frequency measurements and marg...

Research paper thumbnail of Implants in the posterior maxilla: a comparative clinical and radiologic study

International Journal of Oral & Maxillofacial Implants

The aim of this study was to evaluate implants placed according to several methods of sinus floor... more The aim of this study was to evaluate implants placed according to several methods of sinus floor augmentation. Forty-eight patients (median age of 62 years, range 23 to 89) had been treated at least 3 years prior to examination with screw-type implants in the posterior maxilla. Depending on the vertical dimension of the residual bone, 1 of 3 surgical procedures had been performed: sinus lift by lateral antrostomy (SL) in 13 patients; osteotome technique (OT) in 18 patients; standard implantation in 17 patients (control). In each patient 1 implant was randomly chosen for analysis (48 implants with a mean observation time of 4.6 +/- 1.4 years). Examination included probing pocket depth (PPD) measurement and radiographic examination. Radiographs were digitized to assess the marginal bone level. Differences between the groups were tested using analysis of variance, the Student t test and the Kruskal-Wallis test. Mean PPD was 3.0 mm for the SL, 3.1 mm for OT, and 3.1 mm for control. The...

Research paper thumbnail of Experimental zirconia abutments for implant-supported single-tooth restorations in esthetically demanding regions: 4-year results of a prospective clinical study

International Journal of Prosthodontics

This prospective clinical study evaluated an experimental implant abutment made of densely sinter... more This prospective clinical study evaluated an experimental implant abutment made of densely sintered zirconia with respect to peri-implant hard and soft tissue reaction as well as fracture resistance over time. Twenty-seven consecutively treated patients with 54 single-tooth implants were included. Zirconia abutment ingots were individually shaped and set on the implants with gold screws. All-ceramic (Empress I) crowns were cemented using a composite cement. At the 1- and 4-year examinations, reconstructions were evaluated for technical problems (fracture of abutment or crown, loosening of abutment screw). Modified Plaque and simplified Gingival Indices were recorded at implants and neighboring teeth, and peri-implant bone levels were radiographically determined. All but 1 of the 27 patients with 53 restorations could be evaluated at 1 year, and 36 restorations in 18 patients were evaluated 4 years after abutment and crown insertion. The median observation period for the reconstructi...

Research paper thumbnail of Nobel Biocare NEWS

Research paper thumbnail of Experimental zirconia abutments for implant-supported single-tooth restorations in esthetically demanding regions: 4-year results of a prospective clinical study

The International journal of prosthodontics, 2004

PURPOSE This prospective clinical study evaluated an experimental implant abutment made of densel... more PURPOSE This prospective clinical study evaluated an experimental implant abutment made of densely sintered zirconia with respect to peri-implant hard and soft tissue reaction as well as fracture resistance over time. MATERIALS AND METHODS Twenty-seven consecutively treated patients with 54 single-tooth implants were included. Zirconia abutment ingots were individually shaped and set on the implants with gold screws. All-ceramic (Empress I) crowns were cemented using a composite cement. At the 1- and 4-year examinations, reconstructions were evaluated for technical problems (fracture of abutment or crown, loosening of abutment screw). Modified Plaque and simplified Gingival Indices were recorded at implants and neighboring teeth, and peri-implant bone levels were radiographically determined. RESULTS All but 1 of the 27 patients with 53 restorations could be evaluated at 1 year, and 36 restorations in 18 patients were evaluated 4 years after abutment and crown insertion. The median o...

Research paper thumbnail of A systematic review of the survival and complication rates of implant supported single crowns after an observation period of at least 5 years

OBJECTIVES: The objective of this systematic review was to assess the 5-year survival of implant-... more OBJECTIVES: The objective of this systematic review was to assess the 5-year survival of implant-supported single crowns (SCs) and to describe the incidence of biological and technical complications. METHODS: An electronic MEDLINE search complemented by manual searching was conducted to identify prospective and retrospective cohort studies on SCs with a mean follow-up time of at least 5 years. Failure and complication rates were analyzed using random-effects Poisson's regression models to obtain summary estimates of 5-year proportions. RESULTS: Twenty-six studies from an initial yield of 3601 titles were finally selected and data were extracted. In a meta-analysis of these studies, survival of implants supporting SCs was 96.8% [95% confidence interval (CI): 95.9-97.6%] after 5 years. The survival rate of SCs supported by implants was 94.5% (95% CI: 92.5-95.9%) after 5 years of function. The survival rate of metal-ceramic crowns, 95.4% (95% CI: 93.6-96.7%), was significantly (P=0...

Research paper thumbnail of Implants in the posterior maxilla: a comparative clinical and radiologic study

PURPOSE The aim of this study was to evaluate implants placed according to several methods of sin... more PURPOSE The aim of this study was to evaluate implants placed according to several methods of sinus floor augmentation. MATERIALS AND METHODS Forty-eight patients (median age of 62 years, range 23 to 89) had been treated at least 3 years prior to examination with screw-type implants in the posterior maxilla. Depending on the vertical dimension of the residual bone, 1 of 3 surgical procedures had been performed: sinus lift by lateral antrostomy (SL) in 13 patients; osteotome technique (OT) in 18 patients; standard implantation in 17 patients (control). In each patient 1 implant was randomly chosen for analysis (48 implants with a mean observation time of 4.6 +/- 1.4 years). Examination included probing pocket depth (PPD) measurement and radiographic examination. Radiographs were digitized to assess the marginal bone level. Differences between the groups were tested using analysis of variance, the Student t test and the Kruskal-Wallis test. RESULTS Mean PPD was 3.0 mm for the SL, 3.1 ...

Research paper thumbnail of Immediate Occlusal Loading of Branemark SystemR TiUnite™ Implants Placed Predominantly in Soft Bone: 4-Year Results of a Prospective Clinical Study

Clin Implant Dent Relat Res, 2005

Background: Immediate occlusal implant loading has been documented as a viable treatment option f... more Background: Immediate occlusal implant loading has been documented as a viable treatment option for various indications. However, most of the available studies reported on the short-term outcome of this treatment modality.

Research paper thumbnail of A computed tomographic scan–derived customized surgical template and fixed prosthesis for flapless surgery and immediate loading of implants in fully edentulous …

Clinical implant …, 2005

Background: Based on three-dimensional implant planning software for computed tomographic (CT) sc... more Background: Based on three-dimensional implant planning software for computed tomographic (CT) scan data, customized surgical templates and final dental prostheses could be designed to ensure high precision transfer of the implant treatment planning to the operative field and an immediate rigid splinting of the installed implants, respectively.

Research paper thumbnail of The Human Bone–Oxidized Titanium Implant Interface: A Light Microscopic, Scanning Electron Microscopic, Back-Scatter Scanning Electron Microscopic, and Energy-Dispersive X-Ray Study of Clinically Retrieved Dental Implants

Clinical Implant Dentistry and Related Research, 2005

Research paper thumbnail of Implants with an Oxidized Surface Placed Predominately in Soft Bone Quality and Subjected to Immediate Occlusal Loading: Results from an 11-Year Clinical Follow-Up

Clinical implant dentistry and related research, 2016

The purpose of this clinical follow-up was to document the 11-year outcome of implants with a mod... more The purpose of this clinical follow-up was to document the 11-year outcome of implants with a moderately rough oxidized surface subjected to immediate occlusal loading. Twenty-six of 38 patients enrolled in a 5-year prospective study were available for this follow-up analysis, with 33 restorations supported by 66 slightly tapered implants (Brånemark System MkIV, Nobel Biocare, Gothenburg, Sweden). The majority of implants were placed in posterior regions (88%) and into soft bone (76%). Parameters included cumulative survival rate (CSR), radiographic marginal bone level, bleeding on probing (BOP), intrasulcular counts of perio-pathogenic markers (DNA probes), and total bacterial load (TBL). The CSR was 97.1% at 11.2 years mean follow-up. Mean marginal bone remodeling was 0.47 mm (SD 1.09, n = 65) from 1 year postplacement to 11-year follow-up. BOP was absent at most sites (63.6%). No statistically significant differences in TBL or perio-pathogenic marker species were observed at impl...

Research paper thumbnail of Implants with an Oxidized Surface Placed Predominately in Soft Bone Quality and Subjected to Immediate Occlusal Loading: Results from a 7-Year Clinical Follow-Up

Clinical Implant Dentistry and Related Research, 2013

The purpose of this clinical follow-up was to document the 7-year outcome of immediately loaded i... more The purpose of this clinical follow-up was to document the 7-year outcome of immediately loaded implants exhibiting an oxidized surface. Thirty-eight patients received a total of 51 implant-supported fixed prostheses. The restorations were supported by 102 implants, the majority of which were placed in posterior regions (88%) and primarily in soft bone quality (76%). Radiographic examinations were performed at prosthesis insertion, at 1- and 6-month follow-ups, and annually at the 1- through 5-year follow-up visits. Marginal peri-implant soft tissue evaluations were conducted at all these follow-ups. This report presents the results after at least 7 years of loading. After 7 years of prosthetic loading, the cumulative implant survival rate was 97.1% and the mean marginal bone remodeling was -1.51 mm (SD 1.00, n = 73) with significantly more initial remodeling at sites having received marginal guided bone regeneration procedures. A low rate of biological and technical complications was detected after 7 years of function. The quantification of intrasulcular plaque sampling showed no significant difference between teeth and implants. The 7-year follow-up data indicate that the introduced immediate loading protocol is a successful treatment alternative also including regions exhibiting soft bone conditions.

Research paper thumbnail of Two-phase studies on availability of iron in calcareous soils. I. Experiments with alfalfa plants

Research paper thumbnail of Immediate occlusal loading of Brånemark implants applied in various jawbone regions: a prospective, 1-year clinical study

Clinical Implant Dentistry and Related Research, Feb 1, 2001

Background: The original protocol for dental implant treatment ad modum Brånemark was based on su... more Background: The original protocol for dental implant treatment ad modum Brånemark was based on submerged healing prior to loading. For patients, immediate implant function could reduce cost and increase attractiveness of implant treatment.Purpose: The goal of this study was to evaluate the short-term success rate of immediately loaded implants placed in various regions of the jaws.Materials and Methods: Forty-one patients received a total of 127 immediately loaded implants (76 maxillary and 51 mandibular). Seventy-one percent of the patients received their prosthetic restoration the same day and the others within 11 days. All prosthetic constructions were in full contact in centric occlusion. Clinical follow-up examinations were performed at 1 week, 2 weeks, and at 1, 2, 3, 6, and 12 months after implant loading. The study was completed 1 year after loading.Results: Twenty-two implants were lost in 13 patients (including 7 maxillary implants lost in 1 patient). The cumulative success rate of the implants was 82.7% after 1 year of prosthetic loading. All sites with implant losses were re-implanted, using a two-stage technique, with no further complications reported. Ninety-one percent of implants placed in regions other than the posterior maxilla were successful compared with 66% of implants placed in the posterior maxilla. Implants in patients with a parafunctional habit (bruxers) were lost more frequently than those placed in patients with no para-function (41% vs. 12%). Implants subjected to guided bone regeneration were more successful compared with those not subjected to regeneration procedures (90% vs. 67%).Conclusions: The immediate loading concept is a realistic treatment alternative in various jawbone regions except for the posterior part of the maxilla. High occlusal loads should be considered a risk factor. On the other hand, implants in combination with bone defects frequently are penetrating cortical layers to a higher extent, thereby contributing to implant stability during the healing phase and consequently do not inevitably jeopardize the treatment result. However, further controlled clinical studies with larger sample sizes need to be performed to evaluate the influence of different parameters on treatment outcome.

Research paper thumbnail of Implants in the Posterior Maxilla: A Comparative Clinical and Radiologic Study

Purpose: The aim of this study was to evaluate implants placed according to several methods of si... more Purpose: The aim of this study was to evaluate implants placed according to several methods of sinus floor augmentation. Materials and Methods: Forty-eight patients (median age of 62 years, range 23 to 89) had been treated at least 3 years prior to examination with screw-type implants in the posterior maxilla. Depending on the vertical dimension of the residual bone, 1

Research paper thumbnail of Immediate Occlusal Loading of Br�nemark TiUnite? Implants Placed Predominantly in Soft Bone: 1-Year Results of a Prospective Clinical Study

Clin Implant Dent Relat Res, 2003

Research paper thumbnail of Two-phase studies on availability of iron in calcareous soils. III. Contact, and exchange diffusion in ionic membranes

Research paper thumbnail of Experimental zirconia abutments for implant-supported single-tooth restorations in esthetically demanding regions: 4-Year results of a prospective clinical study

The International journal of prosthodontics

This prospective clinical study evaluated an experimental implant abutment made of densely sinter... more This prospective clinical study evaluated an experimental implant abutment made of densely sintered zirconia with respect to peri-implant hard and soft tissue reaction as well as fracture resistance over time. Twenty-seven consecutively treated patients with 54 single-tooth implants were included. Zirconia abutment ingots were individually shaped and set on the implants with gold screws. All-ceramic (Empress I) crowns were cemented using a composite cement. At the 1- and 4-year examinations, reconstructions were evaluated for technical problems (fracture of abutment or crown, loosening of abutment screw). Modified Plaque and simplified Gingival Indices were recorded at implants and neighboring teeth, and peri-implant bone levels were radiographically determined. All but 1 of the 27 patients with 53 restorations could be evaluated at 1 year, and 36 restorations in 18 patients were evaluated 4 years after abutment and crown insertion. The median observation period for the reconstructi...

Research paper thumbnail of Early bone formation around immediately placed two-piece tissue-level zirconia implants with a modified surface: an experimental study in the miniature pig mandible

International Journal of Implant Dentistry

Purpose To histologically examine early bone formation around transmucosal implants and to evalua... more Purpose To histologically examine early bone formation around transmucosal implants and to evaluate the influence of surface characteristics on early peri-implant bone healing using a miniature pig model. For this, commercially available dental implants with a rough zirconia (YTZP) surface were compared to surface-modified Ti control implants at 4 and 8 weeks after placement. Methods Immediately following the extraction of six mandibular premolars, 20 two-piece, tissue-level, screw-shaped YTZP implants (Patent™ Standard Zirconia Implant ø4.1 × 11 mm) with a modified rough blasted before sintering surface were inserted in four adult miniature pigs. In addition, four titanium (Ti) tissue-level implants (Straumann® Standard RN ø4.1 × 10 mm Roxolid®) with a moderate surface (SLActive®), one per animal, were placed as control implants. A histological analysis was performed on the hard tissues after 4 and 8 weeks of transmucosal healing. Results The results show a high rate of osseointegr...

Research paper thumbnail of Al2O3 Particles on Titanium Dental Implant Systems following Sandblasting and Acid-Etching Process

International Journal of Biomaterials, 2019

Dental implants with moderately rough surfaces show enhanced osseointegration and faster bone hea... more Dental implants with moderately rough surfaces show enhanced osseointegration and faster bone healing compared with machined surfaces. The sandblasting and acid-etching (SA) process is one technique to create moderately rough dental implant surfaces. The purpose of this study was to analyse different commercially available implant systems with a SA-modified surface and to explore the widespread notion that they have similar surface properties regarding morphology and cleanliness. SA-modified surfaces of nine implant systems manufactured by Alpha-Bio Tec Ltd, Camlog Biotechnologies AG, Dentsply Sirona Dental GmbH, Neoss Ltd, Osstem Implant Co. Ltd, Institute Straumann AG, and Thommen Medical AG were analyzed using scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDX) and examined for surface cleanliness. Six implants from three different lots were selected per each implant system. Mean particle counts for each implant and the mean size of the particles wer...

Research paper thumbnail of Immediate occlusal loading of Brånemark System TiUnite implants placed predominantly in soft bone: 4-year results of a prospective clinical study

Clinical Implant Dentistry and Related Research, 2005

Immediate occlusal implant loading has been documented as a viable treatment option for various i... more Immediate occlusal implant loading has been documented as a viable treatment option for various indications. However, most of the available studies reported on the short-term outcome of this treatment modality. The purpose of this prospective clinical study was to document, on a long-term basis, the outcome of immediate occlusally loaded Brånemark System Mk IV TiUnite (Nobel Biocare AB, Göteborg, Sweden) implants placed to support fixed reconstructions in various regions of the jaws. Thirty-eight patients received a total of 51 fixed prosthetic reconstructions, all of which were connected on the day of implant insertion. Twenty restorations replaced single teeth, 30 were fixed partial dentures, and 1 was a full-arch fixed lower restoration. These prostheses were supported by 102 Brånemark System Mk IV TiUnite implants (38 maxillary and 64 mandibular), the majority of which were placed in posterior regions (88%) and mainly in soft bone (76%). Resonance frequency measurements and marg...

Research paper thumbnail of Implants in the posterior maxilla: a comparative clinical and radiologic study

International Journal of Oral & Maxillofacial Implants

The aim of this study was to evaluate implants placed according to several methods of sinus floor... more The aim of this study was to evaluate implants placed according to several methods of sinus floor augmentation. Forty-eight patients (median age of 62 years, range 23 to 89) had been treated at least 3 years prior to examination with screw-type implants in the posterior maxilla. Depending on the vertical dimension of the residual bone, 1 of 3 surgical procedures had been performed: sinus lift by lateral antrostomy (SL) in 13 patients; osteotome technique (OT) in 18 patients; standard implantation in 17 patients (control). In each patient 1 implant was randomly chosen for analysis (48 implants with a mean observation time of 4.6 +/- 1.4 years). Examination included probing pocket depth (PPD) measurement and radiographic examination. Radiographs were digitized to assess the marginal bone level. Differences between the groups were tested using analysis of variance, the Student t test and the Kruskal-Wallis test. Mean PPD was 3.0 mm for the SL, 3.1 mm for OT, and 3.1 mm for control. The...

Research paper thumbnail of Experimental zirconia abutments for implant-supported single-tooth restorations in esthetically demanding regions: 4-year results of a prospective clinical study

International Journal of Prosthodontics

This prospective clinical study evaluated an experimental implant abutment made of densely sinter... more This prospective clinical study evaluated an experimental implant abutment made of densely sintered zirconia with respect to peri-implant hard and soft tissue reaction as well as fracture resistance over time. Twenty-seven consecutively treated patients with 54 single-tooth implants were included. Zirconia abutment ingots were individually shaped and set on the implants with gold screws. All-ceramic (Empress I) crowns were cemented using a composite cement. At the 1- and 4-year examinations, reconstructions were evaluated for technical problems (fracture of abutment or crown, loosening of abutment screw). Modified Plaque and simplified Gingival Indices were recorded at implants and neighboring teeth, and peri-implant bone levels were radiographically determined. All but 1 of the 27 patients with 53 restorations could be evaluated at 1 year, and 36 restorations in 18 patients were evaluated 4 years after abutment and crown insertion. The median observation period for the reconstructi...

Research paper thumbnail of Nobel Biocare NEWS

Research paper thumbnail of Experimental zirconia abutments for implant-supported single-tooth restorations in esthetically demanding regions: 4-year results of a prospective clinical study

The International journal of prosthodontics, 2004

PURPOSE This prospective clinical study evaluated an experimental implant abutment made of densel... more PURPOSE This prospective clinical study evaluated an experimental implant abutment made of densely sintered zirconia with respect to peri-implant hard and soft tissue reaction as well as fracture resistance over time. MATERIALS AND METHODS Twenty-seven consecutively treated patients with 54 single-tooth implants were included. Zirconia abutment ingots were individually shaped and set on the implants with gold screws. All-ceramic (Empress I) crowns were cemented using a composite cement. At the 1- and 4-year examinations, reconstructions were evaluated for technical problems (fracture of abutment or crown, loosening of abutment screw). Modified Plaque and simplified Gingival Indices were recorded at implants and neighboring teeth, and peri-implant bone levels were radiographically determined. RESULTS All but 1 of the 27 patients with 53 restorations could be evaluated at 1 year, and 36 restorations in 18 patients were evaluated 4 years after abutment and crown insertion. The median o...

Research paper thumbnail of A systematic review of the survival and complication rates of implant supported single crowns after an observation period of at least 5 years

OBJECTIVES: The objective of this systematic review was to assess the 5-year survival of implant-... more OBJECTIVES: The objective of this systematic review was to assess the 5-year survival of implant-supported single crowns (SCs) and to describe the incidence of biological and technical complications. METHODS: An electronic MEDLINE search complemented by manual searching was conducted to identify prospective and retrospective cohort studies on SCs with a mean follow-up time of at least 5 years. Failure and complication rates were analyzed using random-effects Poisson's regression models to obtain summary estimates of 5-year proportions. RESULTS: Twenty-six studies from an initial yield of 3601 titles were finally selected and data were extracted. In a meta-analysis of these studies, survival of implants supporting SCs was 96.8% [95% confidence interval (CI): 95.9-97.6%] after 5 years. The survival rate of SCs supported by implants was 94.5% (95% CI: 92.5-95.9%) after 5 years of function. The survival rate of metal-ceramic crowns, 95.4% (95% CI: 93.6-96.7%), was significantly (P=0...

Research paper thumbnail of Implants in the posterior maxilla: a comparative clinical and radiologic study

PURPOSE The aim of this study was to evaluate implants placed according to several methods of sin... more PURPOSE The aim of this study was to evaluate implants placed according to several methods of sinus floor augmentation. MATERIALS AND METHODS Forty-eight patients (median age of 62 years, range 23 to 89) had been treated at least 3 years prior to examination with screw-type implants in the posterior maxilla. Depending on the vertical dimension of the residual bone, 1 of 3 surgical procedures had been performed: sinus lift by lateral antrostomy (SL) in 13 patients; osteotome technique (OT) in 18 patients; standard implantation in 17 patients (control). In each patient 1 implant was randomly chosen for analysis (48 implants with a mean observation time of 4.6 +/- 1.4 years). Examination included probing pocket depth (PPD) measurement and radiographic examination. Radiographs were digitized to assess the marginal bone level. Differences between the groups were tested using analysis of variance, the Student t test and the Kruskal-Wallis test. RESULTS Mean PPD was 3.0 mm for the SL, 3.1 ...

Research paper thumbnail of Immediate Occlusal Loading of Branemark SystemR TiUnite™ Implants Placed Predominantly in Soft Bone: 4-Year Results of a Prospective Clinical Study

Clin Implant Dent Relat Res, 2005

Background: Immediate occlusal implant loading has been documented as a viable treatment option f... more Background: Immediate occlusal implant loading has been documented as a viable treatment option for various indications. However, most of the available studies reported on the short-term outcome of this treatment modality.

Research paper thumbnail of A computed tomographic scan–derived customized surgical template and fixed prosthesis for flapless surgery and immediate loading of implants in fully edentulous …

Clinical implant …, 2005

Background: Based on three-dimensional implant planning software for computed tomographic (CT) sc... more Background: Based on three-dimensional implant planning software for computed tomographic (CT) scan data, customized surgical templates and final dental prostheses could be designed to ensure high precision transfer of the implant treatment planning to the operative field and an immediate rigid splinting of the installed implants, respectively.

Research paper thumbnail of The Human Bone–Oxidized Titanium Implant Interface: A Light Microscopic, Scanning Electron Microscopic, Back-Scatter Scanning Electron Microscopic, and Energy-Dispersive X-Ray Study of Clinically Retrieved Dental Implants

Clinical Implant Dentistry and Related Research, 2005

Research paper thumbnail of Implants with an Oxidized Surface Placed Predominately in Soft Bone Quality and Subjected to Immediate Occlusal Loading: Results from an 11-Year Clinical Follow-Up

Clinical implant dentistry and related research, 2016

The purpose of this clinical follow-up was to document the 11-year outcome of implants with a mod... more The purpose of this clinical follow-up was to document the 11-year outcome of implants with a moderately rough oxidized surface subjected to immediate occlusal loading. Twenty-six of 38 patients enrolled in a 5-year prospective study were available for this follow-up analysis, with 33 restorations supported by 66 slightly tapered implants (Brånemark System MkIV, Nobel Biocare, Gothenburg, Sweden). The majority of implants were placed in posterior regions (88%) and into soft bone (76%). Parameters included cumulative survival rate (CSR), radiographic marginal bone level, bleeding on probing (BOP), intrasulcular counts of perio-pathogenic markers (DNA probes), and total bacterial load (TBL). The CSR was 97.1% at 11.2 years mean follow-up. Mean marginal bone remodeling was 0.47 mm (SD 1.09, n = 65) from 1 year postplacement to 11-year follow-up. BOP was absent at most sites (63.6%). No statistically significant differences in TBL or perio-pathogenic marker species were observed at impl...

Research paper thumbnail of Implants with an Oxidized Surface Placed Predominately in Soft Bone Quality and Subjected to Immediate Occlusal Loading: Results from a 7-Year Clinical Follow-Up

Clinical Implant Dentistry and Related Research, 2013

The purpose of this clinical follow-up was to document the 7-year outcome of immediately loaded i... more The purpose of this clinical follow-up was to document the 7-year outcome of immediately loaded implants exhibiting an oxidized surface. Thirty-eight patients received a total of 51 implant-supported fixed prostheses. The restorations were supported by 102 implants, the majority of which were placed in posterior regions (88%) and primarily in soft bone quality (76%). Radiographic examinations were performed at prosthesis insertion, at 1- and 6-month follow-ups, and annually at the 1- through 5-year follow-up visits. Marginal peri-implant soft tissue evaluations were conducted at all these follow-ups. This report presents the results after at least 7 years of loading. After 7 years of prosthetic loading, the cumulative implant survival rate was 97.1% and the mean marginal bone remodeling was -1.51 mm (SD 1.00, n = 73) with significantly more initial remodeling at sites having received marginal guided bone regeneration procedures. A low rate of biological and technical complications was detected after 7 years of function. The quantification of intrasulcular plaque sampling showed no significant difference between teeth and implants. The 7-year follow-up data indicate that the introduced immediate loading protocol is a successful treatment alternative also including regions exhibiting soft bone conditions.

Research paper thumbnail of Two-phase studies on availability of iron in calcareous soils. I. Experiments with alfalfa plants

Research paper thumbnail of Immediate occlusal loading of Brånemark implants applied in various jawbone regions: a prospective, 1-year clinical study

Clinical Implant Dentistry and Related Research, Feb 1, 2001

Background: The original protocol for dental implant treatment ad modum Brånemark was based on su... more Background: The original protocol for dental implant treatment ad modum Brånemark was based on submerged healing prior to loading. For patients, immediate implant function could reduce cost and increase attractiveness of implant treatment.Purpose: The goal of this study was to evaluate the short-term success rate of immediately loaded implants placed in various regions of the jaws.Materials and Methods: Forty-one patients received a total of 127 immediately loaded implants (76 maxillary and 51 mandibular). Seventy-one percent of the patients received their prosthetic restoration the same day and the others within 11 days. All prosthetic constructions were in full contact in centric occlusion. Clinical follow-up examinations were performed at 1 week, 2 weeks, and at 1, 2, 3, 6, and 12 months after implant loading. The study was completed 1 year after loading.Results: Twenty-two implants were lost in 13 patients (including 7 maxillary implants lost in 1 patient). The cumulative success rate of the implants was 82.7% after 1 year of prosthetic loading. All sites with implant losses were re-implanted, using a two-stage technique, with no further complications reported. Ninety-one percent of implants placed in regions other than the posterior maxilla were successful compared with 66% of implants placed in the posterior maxilla. Implants in patients with a parafunctional habit (bruxers) were lost more frequently than those placed in patients with no para-function (41% vs. 12%). Implants subjected to guided bone regeneration were more successful compared with those not subjected to regeneration procedures (90% vs. 67%).Conclusions: The immediate loading concept is a realistic treatment alternative in various jawbone regions except for the posterior part of the maxilla. High occlusal loads should be considered a risk factor. On the other hand, implants in combination with bone defects frequently are penetrating cortical layers to a higher extent, thereby contributing to implant stability during the healing phase and consequently do not inevitably jeopardize the treatment result. However, further controlled clinical studies with larger sample sizes need to be performed to evaluate the influence of different parameters on treatment outcome.

Research paper thumbnail of Implants in the Posterior Maxilla: A Comparative Clinical and Radiologic Study

Purpose: The aim of this study was to evaluate implants placed according to several methods of si... more Purpose: The aim of this study was to evaluate implants placed according to several methods of sinus floor augmentation. Materials and Methods: Forty-eight patients (median age of 62 years, range 23 to 89) had been treated at least 3 years prior to examination with screw-type implants in the posterior maxilla. Depending on the vertical dimension of the residual bone, 1

Research paper thumbnail of Immediate Occlusal Loading of Br�nemark TiUnite? Implants Placed Predominantly in Soft Bone: 1-Year Results of a Prospective Clinical Study

Clin Implant Dent Relat Res, 2003

Research paper thumbnail of Two-phase studies on availability of iron in calcareous soils. III. Contact, and exchange diffusion in ionic membranes

Research paper thumbnail of Experimental zirconia abutments for implant-supported single-tooth restorations in esthetically demanding regions: 4-Year results of a prospective clinical study

The International journal of prosthodontics

This prospective clinical study evaluated an experimental implant abutment made of densely sinter... more This prospective clinical study evaluated an experimental implant abutment made of densely sintered zirconia with respect to peri-implant hard and soft tissue reaction as well as fracture resistance over time. Twenty-seven consecutively treated patients with 54 single-tooth implants were included. Zirconia abutment ingots were individually shaped and set on the implants with gold screws. All-ceramic (Empress I) crowns were cemented using a composite cement. At the 1- and 4-year examinations, reconstructions were evaluated for technical problems (fracture of abutment or crown, loosening of abutment screw). Modified Plaque and simplified Gingival Indices were recorded at implants and neighboring teeth, and peri-implant bone levels were radiographically determined. All but 1 of the 27 patients with 53 restorations could be evaluated at 1 year, and 36 restorations in 18 patients were evaluated 4 years after abutment and crown insertion. The median observation period for the reconstructi...