Antonis Michalopoulos | Aristotle University of Thessaloniki (original) (raw)
Papers by Antonis Michalopoulos
Techniques in Coloproctology, 2010
We present a 71-year-old man with a horseshoe, complex perianal fistula. He was treated by a simp... more We present a 71-year-old man with a horseshoe, complex perianal fistula. He was treated by a simple fistulotomy for the fistula at sixth hour, while fibrin sealant was applied for the complicated one. He is free of symptoms 24 months postoperatively.
Techniques in Coloproctology, 2011
Techniques in coloproctology, 2011
Colorectal cancer (CRC) is a major cause of death in the western world and a leading cause of can... more Colorectal cancer (CRC) is a major cause of death in the western world and a leading cause of cancer-related death. It is one of the most common human malignancies with >300,000 cases both in the United States and in the European Union each year. The present study was conducted to assess differences in various variables of CRC, such as location of the tumor, differentiation, Dukes classification, 5-year survival and possible changes in these patterns during the examined period.
![Research paper thumbnail of Inflammation of solitary caecal diverticula:a rare aetiology of acute abdominal pain [corrected]](https://attachments.academia-assets.com/44249292/thumbnails/1.jpg)
](Techniques in coloproctology, 2011
Caecal diverticula are rare, representing the 3.6% of colonic diverticula. They may have congenit... more Caecal diverticula are rare, representing the 3.6% of colonic diverticula. They may have congenital origin and remain asymptomatic, presenting as an accidental finding. We present a case of a 42-year-old Caucasian woman, admitted with a 12-h history of sudden onset of sharp right iliac fossa pain, anorexia, and nausea. There was leukocytosis (23.49 × 10(3)/μl) and increased C-reactive protein (11.76 mg/dl). CT scan showed an inflamed appendix. At laparotomy, a diffuse caecal phlegmon with an inflammatory solitary caecal diverticula was found. A limited right hemicolectomy was performed. Histological examination confirmed the caecal diverticulitis without malignancy. Post-operative period was uneventful. Three months later, endoscopy showed no diverticula or other pathologies. Solitary caecal diverticulum is very rare, but surgeons must bear this in mind in case of pain in right iliac fossa.
Techniques in coloproctology, 2010
Our case concerns a 52-year-old male with FAP, who was treated surgically by restorative colectom... more Our case concerns a 52-year-old male with FAP, who was treated surgically by restorative colectomy and ileal pouch anal anastomosis. Three years later, he presented with acute epigastric pain and obstructive ileum. While a mass in the left lateral abdominal region was palpated. The patient underwent laparotomy, some adhesions were dissected and biopsies were taken from the mass. Pathological examination revealed a desmoid tumor of the mesentery.
Techniques in coloproctology, 2011
We present the case of a 45-year-old female patient who was admitted with a history of pelvic pai... more We present the case of a 45-year-old female patient who was admitted with a history of pelvic pain, constipation, and dysmenorrhea. CT scan and u/s images revealed cholelithiasis, benign nodular hyperplasia of segment IV of the liver and uterine fibromyoma. During laparotomy, firm adhesions between the posterior wall of the uterus and the rectum were found and the incisional biopsy reveals an undifferentiated adenocarcinoma. Then, total resection of the uterus was performed with en block resection of the adherent part of the rectum and part of the posterior wall of the vagina. The final histopathological report showed the presence of uterine fibromyoma, nodular hyperplasia of the liver and rectal endometriosis without any sign of malignancy. The patient after 5 years of follow up remains healthy. Rectal endometriosis represents an uncommon localization of pelvic endometriosis where the symptoms and clinical findings are non-specific making the definitive preoperative diagnosis diffi...
European Surgery, 2007
Zusammenfassung GRUNDLAGEN: Das Pneumodiastinum oder auch Mediastinalemphysem ist eine krankhaft... more Zusammenfassung GRUNDLAGEN: Das Pneumodiastinum oder auch Mediastinalemphysem ist eine krankhafte Luftansammlung im Mittelfellraum. Auch wenn das Mediastinalemphysem, das aus nichtmallignen Krankenheiten entsteht, hauptsächlich konservativ behandelt wird, in Fällen wo es durch Verletzungen in luftaustauschenden Organen (z. B. Luftröhre, Bronchien) und der Speiseröhre kann dies passieren, muss es unbedingt operativ behandelt werden. Das von einer sehr hohen Mortalitäts- und/oder Morbidität gefolgt. METHODIK:
Journal of Korean Medical Science, 2009
The present case is one of gallstone obstructive ileus due to gallstones 3 yr after laparoscopic ... more The present case is one of gallstone obstructive ileus due to gallstones 3 yr after laparoscopic cholecystectomy. It is interesting because of the sex of the patient, the fact that ileus occurred 3 yr after cholecystectomy and that the localization of the obstruction was an old side-to-side ileoileal anastomosis due to a diverticulectomy following intussusception of Meckels' diverticulum at the age of 3.
Techniques in Coloproctology, 2004
Background Many factors influence survival in colorectal cancer patients, one of them is the muci... more Background Many factors influence survival in colorectal cancer patients, one of them is the mucinous component of the tumour. Mucinous adenocarcinoma is characterized by the extracellular mucin of more than 50% of the tumour volume. Methods From 1970 to 1999, 1160 patients were admitted to our clinic for colorectal cancer. They were divided into four groups according to mucinous character of the tumour, in two time periods of 15 years. Results There was an increase in the incidence of mucinous tumours from 20.8 to 30.5% in the second period. These tumours were more advanced (Dukes' C) and especially right sided (34.5% vs. 17.9%). Five-year survival was increased during the second period but was of a lesser degree in the mucinous group (51.5% vs. 65.5%). Conclusions Colorectal mucinous carcinomas present at a more advanced stage, predominantly in men, with higher right colon location rate, and a worse overall 5-year survival rate than the non-mucinous colorectal cancers.
Techniques in Coloproctology, 2004
Techniques in Coloproctology, 2004
Abstract Background Synchronous and metachronous colorectal carcinoma have an incidence of 2-10%.... more Abstract Background Synchronous and metachronous colorectal carcinoma have an incidence of 2-10%. The purpose of the study was to evaluate the clinical characteristics, the accuracy of diagnostic examinations and the survival of these patients. Methods From 1970 to 1999, 1160 patients with colorectal cancer were admitted to our Department. During follow-up examination 50 patients (4.3%) were found to present with multiple primary colon cancers. Fiftytwo per cent were synchronous and 48% metachronous tumours. Results The overall 5-year survival of the patients was 45.87%. Mortality was 10% for multiple primaries, while in patients with single cancer was 4.1%. The overall 5-year survival of the patients with multiple primaries tumours was 46.67%. Conclusions Patients with colorectal cancer must be fully studied endoscopically. There has been an improvement in survival in recent years due to better surgical techniques, the introduction of more sophisticated examination methods and the meticulous follow-up of patients at risk.
Techniques in Coloproctology, 2011
Techniques in Coloproctology, 2011
Journal of Medical Case Reports, 2007
The granulomatous inflammation of tuberculosis usually involves the lungs and the hilar lymph nod... more The granulomatous inflammation of tuberculosis usually involves the lungs and the hilar lymph nodes. Musculoskeletal tuberculosis (TB) occurs in 1-3% of patients with TB, while TB of the chest wall constitutes 1% to 5% of all cases of musculoskeletal TB. Furthermore, nowadays it is rarer to find extrapulmonary TB in immunocompetent rather that non-immunocompetent patients. The present case reports a fifty-six-year-old immunocompetent man with an anterior chest wall tuberculous abscess. The rarity of the present case relates both to the localization of the tuberculous abscess, and to the fact that the patient was immunocompetent. The diagnosis of musculoskeletal tuberculous infection remains a challenge for clinicians and requires a high index of suspicion. The combination of indolent onset of symptoms, positive tuberculin skin test, and compatible radiographic findings, strongly suggests the diagnosis. TB, however, must be confirmed by positive culture or histologic proof. Prompt diagnosis and treatment are important to prevent serious bone and joint destruction.
Journal of Medical Case Reports, 2010
Introduction: Splenic vein thrombosis results in localized portal hypertension called sinistral p... more Introduction: Splenic vein thrombosis results in localized portal hypertension called sinistral portal hypertension, which may also lead to massive upper gastrointestinal bleeding. Symptomatic sinistral portal hypertension is usually best treated by splenectomy, but interventional radiological techniques are safe and effective alternatives in the management of a massive hemorrhage, particularly in cases that have a high surgical risk.
Journal of Medical Case Reports, 2011
Introduction: Primary intestinal tuberculosis is a rare variant of tuberculosis. The preferred tr... more Introduction: Primary intestinal tuberculosis is a rare variant of tuberculosis. The preferred treatment is usually pharmaceutical, but surgery may be required for complicated cases.
Techniques in coloproctology, 2011
Colorectal cancer (CRC) is a major cause of death in the western world and a leading cause of can... more Colorectal cancer (CRC) is a major cause of death in the western world and a leading cause of cancer-related death. It is one of the most common human malignancies with >300,000 cases both in the United States and in the European Union each year. The present study was conducted to assess differences in various variables of CRC, such as location of the tumor, differentiation, Dukes classification, 5-year survival and possible changes in these patterns during the examined period.
![Research paper thumbnail of Inflammation of solitary caecal diverticula:a rare aetiology of acute abdominal pain [corrected]](https://attachments.academia-assets.com/44358815/thumbnails/1.jpg)
](Techniques in coloproctology, 2011
Caecal diverticula are rare, representing the 3.6% of colonic diverticula. They may have congenit... more Caecal diverticula are rare, representing the 3.6% of colonic diverticula. They may have congenital origin and remain asymptomatic, presenting as an accidental finding. We present a case of a 42-year-old Caucasian woman, admitted with a 12-h history of sudden onset of sharp right iliac fossa pain, anorexia, and nausea. There was leukocytosis (23.49 × 10(3)/μl) and increased C-reactive protein (11.76 mg/dl). CT scan showed an inflamed appendix. At laparotomy, a diffuse caecal phlegmon with an inflammatory solitary caecal diverticula was found. A limited right hemicolectomy was performed. Histological examination confirmed the caecal diverticulitis without malignancy. Post-operative period was uneventful. Three months later, endoscopy showed no diverticula or other pathologies. Solitary caecal diverticulum is very rare, but surgeons must bear this in mind in case of pain in right iliac fossa.
Journal of medical case reports, 2008
Solid pseudo-papillary tumors of the pancreas are rare and typically present in young female pati... more Solid pseudo-papillary tumors of the pancreas are rare and typically present in young female patients. They are slowly growing masses that may attain large size, and are of low malignant potential. Surgical resection is usually curative.
Southern medical journal, 2009
Three cases of endometriosis infiltrating the round ligament are presented. The initial diagnosis... more Three cases of endometriosis infiltrating the round ligament are presented. The initial diagnosis was irreducible hernia, since this rare nosologic entity often causes unusual preoperative symptoms and diagnostic problems. Diagnosis is frequently made by histologic examination. The rarity of inguinal endometriosis should not exclude it from a possible diagnosis in cases with a painful mass in the inguinal region in a fertile woman, especially if the groin mass is associated in size and tenderness with menstrual variability. Surgery is the treatment of choice and is curative; laparoscopy is suggested during the same operation to evaluate the intraperitoneal conditions.
Techniques in Coloproctology, 2010
We present a 71-year-old man with a horseshoe, complex perianal fistula. He was treated by a simp... more We present a 71-year-old man with a horseshoe, complex perianal fistula. He was treated by a simple fistulotomy for the fistula at sixth hour, while fibrin sealant was applied for the complicated one. He is free of symptoms 24 months postoperatively.
Techniques in Coloproctology, 2011
Techniques in coloproctology, 2011
Colorectal cancer (CRC) is a major cause of death in the western world and a leading cause of can... more Colorectal cancer (CRC) is a major cause of death in the western world and a leading cause of cancer-related death. It is one of the most common human malignancies with >300,000 cases both in the United States and in the European Union each year. The present study was conducted to assess differences in various variables of CRC, such as location of the tumor, differentiation, Dukes classification, 5-year survival and possible changes in these patterns during the examined period.
Techniques in coloproctology, 2011
Caecal diverticula are rare, representing the 3.6% of colonic diverticula. They may have congenit... more Caecal diverticula are rare, representing the 3.6% of colonic diverticula. They may have congenital origin and remain asymptomatic, presenting as an accidental finding. We present a case of a 42-year-old Caucasian woman, admitted with a 12-h history of sudden onset of sharp right iliac fossa pain, anorexia, and nausea. There was leukocytosis (23.49 × 10(3)/μl) and increased C-reactive protein (11.76 mg/dl). CT scan showed an inflamed appendix. At laparotomy, a diffuse caecal phlegmon with an inflammatory solitary caecal diverticula was found. A limited right hemicolectomy was performed. Histological examination confirmed the caecal diverticulitis without malignancy. Post-operative period was uneventful. Three months later, endoscopy showed no diverticula or other pathologies. Solitary caecal diverticulum is very rare, but surgeons must bear this in mind in case of pain in right iliac fossa.
Techniques in coloproctology, 2010
Our case concerns a 52-year-old male with FAP, who was treated surgically by restorative colectom... more Our case concerns a 52-year-old male with FAP, who was treated surgically by restorative colectomy and ileal pouch anal anastomosis. Three years later, he presented with acute epigastric pain and obstructive ileum. While a mass in the left lateral abdominal region was palpated. The patient underwent laparotomy, some adhesions were dissected and biopsies were taken from the mass. Pathological examination revealed a desmoid tumor of the mesentery.
Techniques in coloproctology, 2011
We present the case of a 45-year-old female patient who was admitted with a history of pelvic pai... more We present the case of a 45-year-old female patient who was admitted with a history of pelvic pain, constipation, and dysmenorrhea. CT scan and u/s images revealed cholelithiasis, benign nodular hyperplasia of segment IV of the liver and uterine fibromyoma. During laparotomy, firm adhesions between the posterior wall of the uterus and the rectum were found and the incisional biopsy reveals an undifferentiated adenocarcinoma. Then, total resection of the uterus was performed with en block resection of the adherent part of the rectum and part of the posterior wall of the vagina. The final histopathological report showed the presence of uterine fibromyoma, nodular hyperplasia of the liver and rectal endometriosis without any sign of malignancy. The patient after 5 years of follow up remains healthy. Rectal endometriosis represents an uncommon localization of pelvic endometriosis where the symptoms and clinical findings are non-specific making the definitive preoperative diagnosis diffi...
European Surgery, 2007
Zusammenfassung GRUNDLAGEN: Das Pneumodiastinum oder auch Mediastinalemphysem ist eine krankhaft... more Zusammenfassung GRUNDLAGEN: Das Pneumodiastinum oder auch Mediastinalemphysem ist eine krankhafte Luftansammlung im Mittelfellraum. Auch wenn das Mediastinalemphysem, das aus nichtmallignen Krankenheiten entsteht, hauptsächlich konservativ behandelt wird, in Fällen wo es durch Verletzungen in luftaustauschenden Organen (z. B. Luftröhre, Bronchien) und der Speiseröhre kann dies passieren, muss es unbedingt operativ behandelt werden. Das von einer sehr hohen Mortalitäts- und/oder Morbidität gefolgt. METHODIK:
Journal of Korean Medical Science, 2009
The present case is one of gallstone obstructive ileus due to gallstones 3 yr after laparoscopic ... more The present case is one of gallstone obstructive ileus due to gallstones 3 yr after laparoscopic cholecystectomy. It is interesting because of the sex of the patient, the fact that ileus occurred 3 yr after cholecystectomy and that the localization of the obstruction was an old side-to-side ileoileal anastomosis due to a diverticulectomy following intussusception of Meckels' diverticulum at the age of 3.
Techniques in Coloproctology, 2004
Background Many factors influence survival in colorectal cancer patients, one of them is the muci... more Background Many factors influence survival in colorectal cancer patients, one of them is the mucinous component of the tumour. Mucinous adenocarcinoma is characterized by the extracellular mucin of more than 50% of the tumour volume. Methods From 1970 to 1999, 1160 patients were admitted to our clinic for colorectal cancer. They were divided into four groups according to mucinous character of the tumour, in two time periods of 15 years. Results There was an increase in the incidence of mucinous tumours from 20.8 to 30.5% in the second period. These tumours were more advanced (Dukes' C) and especially right sided (34.5% vs. 17.9%). Five-year survival was increased during the second period but was of a lesser degree in the mucinous group (51.5% vs. 65.5%). Conclusions Colorectal mucinous carcinomas present at a more advanced stage, predominantly in men, with higher right colon location rate, and a worse overall 5-year survival rate than the non-mucinous colorectal cancers.
Techniques in Coloproctology, 2004
Techniques in Coloproctology, 2004
Abstract Background Synchronous and metachronous colorectal carcinoma have an incidence of 2-10%.... more Abstract Background Synchronous and metachronous colorectal carcinoma have an incidence of 2-10%. The purpose of the study was to evaluate the clinical characteristics, the accuracy of diagnostic examinations and the survival of these patients. Methods From 1970 to 1999, 1160 patients with colorectal cancer were admitted to our Department. During follow-up examination 50 patients (4.3%) were found to present with multiple primary colon cancers. Fiftytwo per cent were synchronous and 48% metachronous tumours. Results The overall 5-year survival of the patients was 45.87%. Mortality was 10% for multiple primaries, while in patients with single cancer was 4.1%. The overall 5-year survival of the patients with multiple primaries tumours was 46.67%. Conclusions Patients with colorectal cancer must be fully studied endoscopically. There has been an improvement in survival in recent years due to better surgical techniques, the introduction of more sophisticated examination methods and the meticulous follow-up of patients at risk.
Techniques in Coloproctology, 2011
Techniques in Coloproctology, 2011
Journal of Medical Case Reports, 2007
The granulomatous inflammation of tuberculosis usually involves the lungs and the hilar lymph nod... more The granulomatous inflammation of tuberculosis usually involves the lungs and the hilar lymph nodes. Musculoskeletal tuberculosis (TB) occurs in 1-3% of patients with TB, while TB of the chest wall constitutes 1% to 5% of all cases of musculoskeletal TB. Furthermore, nowadays it is rarer to find extrapulmonary TB in immunocompetent rather that non-immunocompetent patients. The present case reports a fifty-six-year-old immunocompetent man with an anterior chest wall tuberculous abscess. The rarity of the present case relates both to the localization of the tuberculous abscess, and to the fact that the patient was immunocompetent. The diagnosis of musculoskeletal tuberculous infection remains a challenge for clinicians and requires a high index of suspicion. The combination of indolent onset of symptoms, positive tuberculin skin test, and compatible radiographic findings, strongly suggests the diagnosis. TB, however, must be confirmed by positive culture or histologic proof. Prompt diagnosis and treatment are important to prevent serious bone and joint destruction.
Journal of Medical Case Reports, 2010
Introduction: Splenic vein thrombosis results in localized portal hypertension called sinistral p... more Introduction: Splenic vein thrombosis results in localized portal hypertension called sinistral portal hypertension, which may also lead to massive upper gastrointestinal bleeding. Symptomatic sinistral portal hypertension is usually best treated by splenectomy, but interventional radiological techniques are safe and effective alternatives in the management of a massive hemorrhage, particularly in cases that have a high surgical risk.
Journal of Medical Case Reports, 2011
Introduction: Primary intestinal tuberculosis is a rare variant of tuberculosis. The preferred tr... more Introduction: Primary intestinal tuberculosis is a rare variant of tuberculosis. The preferred treatment is usually pharmaceutical, but surgery may be required for complicated cases.
Techniques in coloproctology, 2011
Colorectal cancer (CRC) is a major cause of death in the western world and a leading cause of can... more Colorectal cancer (CRC) is a major cause of death in the western world and a leading cause of cancer-related death. It is one of the most common human malignancies with >300,000 cases both in the United States and in the European Union each year. The present study was conducted to assess differences in various variables of CRC, such as location of the tumor, differentiation, Dukes classification, 5-year survival and possible changes in these patterns during the examined period.
Techniques in coloproctology, 2011
Caecal diverticula are rare, representing the 3.6% of colonic diverticula. They may have congenit... more Caecal diverticula are rare, representing the 3.6% of colonic diverticula. They may have congenital origin and remain asymptomatic, presenting as an accidental finding. We present a case of a 42-year-old Caucasian woman, admitted with a 12-h history of sudden onset of sharp right iliac fossa pain, anorexia, and nausea. There was leukocytosis (23.49 × 10(3)/μl) and increased C-reactive protein (11.76 mg/dl). CT scan showed an inflamed appendix. At laparotomy, a diffuse caecal phlegmon with an inflammatory solitary caecal diverticula was found. A limited right hemicolectomy was performed. Histological examination confirmed the caecal diverticulitis without malignancy. Post-operative period was uneventful. Three months later, endoscopy showed no diverticula or other pathologies. Solitary caecal diverticulum is very rare, but surgeons must bear this in mind in case of pain in right iliac fossa.
Journal of medical case reports, 2008
Solid pseudo-papillary tumors of the pancreas are rare and typically present in young female pati... more Solid pseudo-papillary tumors of the pancreas are rare and typically present in young female patients. They are slowly growing masses that may attain large size, and are of low malignant potential. Surgical resection is usually curative.
Southern medical journal, 2009
Three cases of endometriosis infiltrating the round ligament are presented. The initial diagnosis... more Three cases of endometriosis infiltrating the round ligament are presented. The initial diagnosis was irreducible hernia, since this rare nosologic entity often causes unusual preoperative symptoms and diagnostic problems. Diagnosis is frequently made by histologic examination. The rarity of inguinal endometriosis should not exclude it from a possible diagnosis in cases with a painful mass in the inguinal region in a fertile woman, especially if the groin mass is associated in size and tenderness with menstrual variability. Surgery is the treatment of choice and is curative; laparoscopy is suggested during the same operation to evaluate the intraperitoneal conditions.