Shahabaj Bagwan | Dr.Babasaheb Ambedkar Marathwada University (original) (raw)

ORGANIC SYNTHESIS by Shahabaj Bagwan

Research paper thumbnail of A SIMPLE, EFFICIENT AND GREEN PROCEDURE FOR THE SYNTHESIS OF 2, 4, 5-TRISUBSTITUTED IMIDAZOLE DERIVATIVES USING NOVEL PEG-SOCl AS A CATALYST

International Journal of Pharmaceutical Sciences and Research., 2023

A facile, highly efficient, simple, and convenient method for synthesizing 2, 4, 5-trisubstituted... more A facile, highly efficient, simple, and convenient method for synthesizing 2, 4, 5-trisubstituted imidazole derivatives from the condensation of various substituted benzaldehyde, benzil, and ammonium acetate by using a catalytic amount of PEG-SOCl in the presence of water at room temperature or under microwave irradiation. PEG-SOCl is an effective heterogeneous catalyst and easy to separate. We have investigated that PEG-SOCl catalytic system was excellent recycled and reused three times without any loss of catalytic activity. PEG-SOCl act as a green catalyst, low-cost, non-volatile, non-hazardous, environmental friendly catalyst, and water is a green solvent reaction carried out at room temperature or under microwave radiation method shows greater advantages because it has contributed in the green chemistry aspects. The prepared catalyst was analyzed by analytical methods such as infrared spectrum (IR), X-Ray diffraction pattern (XRD), thermo-gravimetric analysis (TGA), and BET surface analysis. Spectroscopic techniques identified the synthesized pure product (1j), including infra-red (IR) spectrum, 1 H and 13 C NMR spectrum and Mass (LC-MS) spectrometry.

Research paper thumbnail of MORINGA OLEIFERA (MO) SEED CATALYZED THE SYNTHESIS OF BENZIMIDAZOLE DERIVATIVES

International Journal of Pharmaceutical Sciences and Research., 2022

A simple, one-pot, and efficient method for the synthesis of benzimidazole derivatives via the co... more A simple, one-pot, and efficient method for the synthesis of benzimidazole derivatives via the condensation of ophenylenediamine and substituted aromatic aldehydes in the presence of Moringa oleifera (MO) seed extract acts as a biocatalyst under microwave irradiation. The method provides several advantages such as simple operation, clean reaction ways, and high to the excellent yield of product. The aqueous extract of Moringa oleifera (MO) seed as a green catalyst corresponds to an excellent yield for the synthesis of 2, 4, 5-trisubstituted imidazole derivatives under microwave irradiation method as a greener heating technique and one-pot multicomponent reaction acts as a green routine. All synthesized compounds were characterized by spectroscopic techniques such as FT-IR, 1H-NMR, 13C-NMR and LC-MS analysis.

Research paper thumbnail of PREPARATION OF 2,4,5-TRIARYLIMIDAZOLE DERIVATIVES USING GREEN Syzygium Cumini SEED CATALYST

RASAYAN Journal of Chemistry, 2022

A simple, efficient, one-pot, and green synthesis of 2, 4, 5-triaryl imidazole was carried by thr... more A simple, efficient, one-pot, and green synthesis of 2, 4, 5-triaryl imidazole was carried by three constituent reactions of benzil, ammonium acetate, and substituted aromatic aldehyde by using Syzygium cumini seed extract as a catalyst under reflux. The aqueous extract of Syzygium cumini seed as a biocatalyst is associated with high to excellent yield, green synthetic roughness, low reaction time, and eco-friendly operation. The catalyst contains different phytochemical contents, which are detrimental to improving the acidity of aqueous extract. The seed extract is nonhazardous, non-inflammable, low-cost, and environmentally green. All synthesized compounds were characterized by sophisticated spectroscopic techniques such as FT-IR, 1 H-NMR, 13 C-NMR, and Mass spectrometry.

Research paper thumbnail of Green Protocol for the Synthesis of 2, 4, 5-Trisubstituted Imidazole Derivatives Catalyzed by Copper Oxide Nanoparticles (Copper Oxide NPs

International Journal of Advance Research in Science, Communication and Technology, 2022

A facile, efficient and one pot synthesis of 2, 4, 5-trisubstituted imidazole derivatives via the... more A facile, efficient and one pot synthesis of 2, 4, 5-trisubstituted imidazole derivatives via the condensation of benzil, substituted benzaldehydes and ammonium acetate using copper oxide NPs in presence of ethanol as a solvent under reflux. Copper oxide NPs is an effective catalyst and easy for separation. Copper oxide NPs also as a green catalyst, low cost, environmental friendly catalyst used for these reaction carried out under reflux. The remarkable advantages of this methodology are simple operation, short reaction time, clean reaction ways and high to excellent yield of product. The synthesized Copper oxides NPs are characterized by UV-Visible spectra, X-ray Diffraction (XRD) and Field Emission-Scanning electron microscopy (FE-SEM) analysis. In UV-visible spectra, a peak was obtained at 427.50 nm due to inter band transmission of core electron. The pattern of XRD analysis showed particle size of 25-85 Nm and it reveals high crystallinity of the Copper oxide NPs. In FE-SEM, the average size of synthesized nanoparticles is about 55 nm according to measurement software.

Research paper thumbnail of An Efficient and One Pot Synthesis of 2,4,5-Trisubstituted Imidazole Derivatives Catalyzed by Silver Nanoparticles.

Asian Journal of Chemistry, 2022

Silver nanoparticles (AgNPs) have been used as an excellent and highly efficient catalyst for one... more Silver nanoparticles (AgNPs) have been used as an excellent and highly efficient catalyst for one pot synthesis of 2,4,5-trisubstituted imidazole derivatives in presence of ethanol as a solvent. This synthetic route involves multicomponent reaction of benzil, substituted aromatic aldehydes and ammonium acetate under reflux. The synthesized silver nanoparticles were characterized by UV-visible spectroscopy (UV-visible), X-ray diffraction (XRD) pattern, scanning electronic microscope (SEM) analysis. The process was simple and environmentally benign with high to excellent yield. The methods provides several advantages such as simple operation, clean reaction profile, short reaction time and high yield of product. The synthesized silver nanoparticles as catalyst was non-toxic, eco-friendly, low cost and green synthetic method.

Papers by Shahabaj Bagwan

Research paper thumbnail of PREPARATION OF 2,4,5-TRIARYLIMIDAZOLE DERIVATIVES USING GREEN Syzygium Cumini SEED CATALYST

RASAYAN Journal of Chemistry

A simple, efficient, one-pot, and green synthesis of 2, 4, 5-triaryl imidazole was carried by thr... more A simple, efficient, one-pot, and green synthesis of 2, 4, 5-triaryl imidazole was carried by three constituent reactions of benzil, ammonium acetate, and substituted aromatic aldehyde by using Syzygium cumini seed extract as a catalyst under reflux. The aqueous extract of Syzygium cumini seed as a biocatalyst is associated with high to excellent yield, green synthetic roughness, low reaction time, and eco-friendly operation. The catalyst contains different phytochemical contents, which are detrimental to improving the acidity of aqueous extract. The seed extract is nonhazardous, non-inflammable, low-cost, and environmentally green. All synthesized compounds were characterized by sophisticated spectroscopic techniques such as FT-IR, 1H-NMR, 13C-NMR, and Mass spectrometry.

Research paper thumbnail of An Efficient and One Pot Synthesis of 2,4,5-Trisubstituted Imidazole Derivatives Catalyzed by Silver Nanoparticles

Asian Journal of Chemistry, 2022

Silver nanoparticles (AgNPs) have been used as an excellent and highly efficient catalyst for one... more Silver nanoparticles (AgNPs) have been used as an excellent and highly efficient catalyst for one pot synthesis of 2,4,5-trisubstituted imidazole derivatives in presence of ethanol as a solvent. This synthetic route involves multicomponent reaction of benzil, substituted aromatic aldehydes and ammonium acetate under reflux. The synthesized silver nanoparticles were characterized by UV-visible spectroscopy (UV-visible), X-ray diffraction (XRD) pattern, scanning electronic microscope (SEM) analysis. The process was simple and environmentally benign with high to excellent yield. The methods provides several advantages such as simple operation, clean reaction profile, short reaction time and high yield of product. The synthesized silver nanoparticles as catalyst was non-toxic, eco-friendly, low cost and green synthetic method.

Research paper thumbnail of GREEN APPROACH FOR THE PREPARATION OF 2-ARYL-1, 3-BENZOXAZOLE DERIVATIVES BY USING Amla Fruit EXTRACT

RASAYAN Journal of Chemistry

One pot, rapid and green preparation of 2-aryl-1,3-benzoxazole and their derivatives via the reac... more One pot, rapid and green preparation of 2-aryl-1,3-benzoxazole and their derivatives via the reaction of o-amino phenol and substituted aryl aldehydes by using amla fruit extract at room temperature or under microwave radiation. Amla fruit extract is a biocatalyst associated with low-cost, inexpensive, non-volatile, and environmentally friendly. The prepared catalyst shows many chemical, phytochemical, and anti-oxidant constituents, which are unfavorable to increase the acidic contents of water extract. The noteworthy benefits of this process are simple, easy methodology, an excellent yield of product, minimum time of reaction, ease of separation, easy work, and green catalyst. The prepared compound where characterized by analytical or spectroscopic techniques such as FT-IR (infrared) spectrum, H1-NMR, C13-NMR, and LC-MS (Mass) analysis.

Research paper thumbnail of A SIMPLE, EFFICIENT AND GREEN PROCEDURE FOR THE SYNTHESIS OF 2, 4, 5-TRISUBSTITUTED IMIDAZOLE DERIVATIVES USING NOVEL PEG-SOCl AS A CATALYST

International Journal of Pharmaceutical Sciences and Research., 2023

A facile, highly efficient, simple, and convenient method for synthesizing 2, 4, 5-trisubstituted... more A facile, highly efficient, simple, and convenient method for synthesizing 2, 4, 5-trisubstituted imidazole derivatives from the condensation of various substituted benzaldehyde, benzil, and ammonium acetate by using a catalytic amount of PEG-SOCl in the presence of water at room temperature or under microwave irradiation. PEG-SOCl is an effective heterogeneous catalyst and easy to separate. We have investigated that PEG-SOCl catalytic system was excellent recycled and reused three times without any loss of catalytic activity. PEG-SOCl act as a green catalyst, low-cost, non-volatile, non-hazardous, environmental friendly catalyst, and water is a green solvent reaction carried out at room temperature or under microwave radiation method shows greater advantages because it has contributed in the green chemistry aspects. The prepared catalyst was analyzed by analytical methods such as infrared spectrum (IR), X-Ray diffraction pattern (XRD), thermo-gravimetric analysis (TGA), and BET surface analysis. Spectroscopic techniques identified the synthesized pure product (1j), including infra-red (IR) spectrum, 1 H and 13 C NMR spectrum and Mass (LC-MS) spectrometry.

Research paper thumbnail of MORINGA OLEIFERA (MO) SEED CATALYZED THE SYNTHESIS OF BENZIMIDAZOLE DERIVATIVES

International Journal of Pharmaceutical Sciences and Research., 2022

A simple, one-pot, and efficient method for the synthesis of benzimidazole derivatives via the co... more A simple, one-pot, and efficient method for the synthesis of benzimidazole derivatives via the condensation of ophenylenediamine and substituted aromatic aldehydes in the presence of Moringa oleifera (MO) seed extract acts as a biocatalyst under microwave irradiation. The method provides several advantages such as simple operation, clean reaction ways, and high to the excellent yield of product. The aqueous extract of Moringa oleifera (MO) seed as a green catalyst corresponds to an excellent yield for the synthesis of 2, 4, 5-trisubstituted imidazole derivatives under microwave irradiation method as a greener heating technique and one-pot multicomponent reaction acts as a green routine. All synthesized compounds were characterized by spectroscopic techniques such as FT-IR, 1H-NMR, 13C-NMR and LC-MS analysis.

Research paper thumbnail of PREPARATION OF 2,4,5-TRIARYLIMIDAZOLE DERIVATIVES USING GREEN Syzygium Cumini SEED CATALYST

RASAYAN Journal of Chemistry, 2022

A simple, efficient, one-pot, and green synthesis of 2, 4, 5-triaryl imidazole was carried by thr... more A simple, efficient, one-pot, and green synthesis of 2, 4, 5-triaryl imidazole was carried by three constituent reactions of benzil, ammonium acetate, and substituted aromatic aldehyde by using Syzygium cumini seed extract as a catalyst under reflux. The aqueous extract of Syzygium cumini seed as a biocatalyst is associated with high to excellent yield, green synthetic roughness, low reaction time, and eco-friendly operation. The catalyst contains different phytochemical contents, which are detrimental to improving the acidity of aqueous extract. The seed extract is nonhazardous, non-inflammable, low-cost, and environmentally green. All synthesized compounds were characterized by sophisticated spectroscopic techniques such as FT-IR, 1 H-NMR, 13 C-NMR, and Mass spectrometry.

Research paper thumbnail of Green Protocol for the Synthesis of 2, 4, 5-Trisubstituted Imidazole Derivatives Catalyzed by Copper Oxide Nanoparticles (Copper Oxide NPs

International Journal of Advance Research in Science, Communication and Technology, 2022

A facile, efficient and one pot synthesis of 2, 4, 5-trisubstituted imidazole derivatives via the... more A facile, efficient and one pot synthesis of 2, 4, 5-trisubstituted imidazole derivatives via the condensation of benzil, substituted benzaldehydes and ammonium acetate using copper oxide NPs in presence of ethanol as a solvent under reflux. Copper oxide NPs is an effective catalyst and easy for separation. Copper oxide NPs also as a green catalyst, low cost, environmental friendly catalyst used for these reaction carried out under reflux. The remarkable advantages of this methodology are simple operation, short reaction time, clean reaction ways and high to excellent yield of product. The synthesized Copper oxides NPs are characterized by UV-Visible spectra, X-ray Diffraction (XRD) and Field Emission-Scanning electron microscopy (FE-SEM) analysis. In UV-visible spectra, a peak was obtained at 427.50 nm due to inter band transmission of core electron. The pattern of XRD analysis showed particle size of 25-85 Nm and it reveals high crystallinity of the Copper oxide NPs. In FE-SEM, the average size of synthesized nanoparticles is about 55 nm according to measurement software.

Research paper thumbnail of An Efficient and One Pot Synthesis of 2,4,5-Trisubstituted Imidazole Derivatives Catalyzed by Silver Nanoparticles.

Asian Journal of Chemistry, 2022

Silver nanoparticles (AgNPs) have been used as an excellent and highly efficient catalyst for one... more Silver nanoparticles (AgNPs) have been used as an excellent and highly efficient catalyst for one pot synthesis of 2,4,5-trisubstituted imidazole derivatives in presence of ethanol as a solvent. This synthetic route involves multicomponent reaction of benzil, substituted aromatic aldehydes and ammonium acetate under reflux. The synthesized silver nanoparticles were characterized by UV-visible spectroscopy (UV-visible), X-ray diffraction (XRD) pattern, scanning electronic microscope (SEM) analysis. The process was simple and environmentally benign with high to excellent yield. The methods provides several advantages such as simple operation, clean reaction profile, short reaction time and high yield of product. The synthesized silver nanoparticles as catalyst was non-toxic, eco-friendly, low cost and green synthetic method.

Research paper thumbnail of PREPARATION OF 2,4,5-TRIARYLIMIDAZOLE DERIVATIVES USING GREEN Syzygium Cumini SEED CATALYST

RASAYAN Journal of Chemistry

A simple, efficient, one-pot, and green synthesis of 2, 4, 5-triaryl imidazole was carried by thr... more A simple, efficient, one-pot, and green synthesis of 2, 4, 5-triaryl imidazole was carried by three constituent reactions of benzil, ammonium acetate, and substituted aromatic aldehyde by using Syzygium cumini seed extract as a catalyst under reflux. The aqueous extract of Syzygium cumini seed as a biocatalyst is associated with high to excellent yield, green synthetic roughness, low reaction time, and eco-friendly operation. The catalyst contains different phytochemical contents, which are detrimental to improving the acidity of aqueous extract. The seed extract is nonhazardous, non-inflammable, low-cost, and environmentally green. All synthesized compounds were characterized by sophisticated spectroscopic techniques such as FT-IR, 1H-NMR, 13C-NMR, and Mass spectrometry.

Research paper thumbnail of An Efficient and One Pot Synthesis of 2,4,5-Trisubstituted Imidazole Derivatives Catalyzed by Silver Nanoparticles

Asian Journal of Chemistry, 2022

Silver nanoparticles (AgNPs) have been used as an excellent and highly efficient catalyst for one... more Silver nanoparticles (AgNPs) have been used as an excellent and highly efficient catalyst for one pot synthesis of 2,4,5-trisubstituted imidazole derivatives in presence of ethanol as a solvent. This synthetic route involves multicomponent reaction of benzil, substituted aromatic aldehydes and ammonium acetate under reflux. The synthesized silver nanoparticles were characterized by UV-visible spectroscopy (UV-visible), X-ray diffraction (XRD) pattern, scanning electronic microscope (SEM) analysis. The process was simple and environmentally benign with high to excellent yield. The methods provides several advantages such as simple operation, clean reaction profile, short reaction time and high yield of product. The synthesized silver nanoparticles as catalyst was non-toxic, eco-friendly, low cost and green synthetic method.

Research paper thumbnail of GREEN APPROACH FOR THE PREPARATION OF 2-ARYL-1, 3-BENZOXAZOLE DERIVATIVES BY USING Amla Fruit EXTRACT

RASAYAN Journal of Chemistry

One pot, rapid and green preparation of 2-aryl-1,3-benzoxazole and their derivatives via the reac... more One pot, rapid and green preparation of 2-aryl-1,3-benzoxazole and their derivatives via the reaction of o-amino phenol and substituted aryl aldehydes by using amla fruit extract at room temperature or under microwave radiation. Amla fruit extract is a biocatalyst associated with low-cost, inexpensive, non-volatile, and environmentally friendly. The prepared catalyst shows many chemical, phytochemical, and anti-oxidant constituents, which are unfavorable to increase the acidic contents of water extract. The noteworthy benefits of this process are simple, easy methodology, an excellent yield of product, minimum time of reaction, ease of separation, easy work, and green catalyst. The prepared compound where characterized by analytical or spectroscopic techniques such as FT-IR (infrared) spectrum, H1-NMR, C13-NMR, and LC-MS (Mass) analysis.