Leila Itani | Beirut Arab University (original) (raw)

Papers by Leila Itani

Current developments in nutrition, Jun 1, 2019

Objectives The study aims to identify lifestyle patterns in a sample of Lebanese adults and exami... more Objectives The study aims to identify lifestyle patterns in a sample of Lebanese adults and examine the association of these patterns with Metabolically Healthy Overweight and Obesity (MHOv/O). Methods This study is based on a cross-sectional survey of Lebanese adults living in Greater Beirut area (n = 305), and which was conducted in 2014. Dietary intake assessment was performed using an 80-item semi-quantitative food frequency questionnaire. The identification of MHOv/O was based on the ATP-III criteria. Principal Component Factor Analysis was implemented to derive lifestyle patterns, including variables related to dietary intake, eating at home, alcohol consumption, drinking water, sleeping difficulties, smoking and physical activity. Results Two lifestyle patterns were identified in the study population: the "Unhealthy" pattern which was characterized by cigarette smoking, fast food, soft drinks and alcohol consumption . Eating at home loaded negatively on this pattern. The "Healthy" lifestyle pattern was characterized by positive loadings of food groups such as milk and dairy products, fruits and vegetables. Sleeping difficulties loaded negatively on this pattern, while physical activity had a positive loading. Multiple logistic regression analyses was performed. The results showed that subjects belonging to the 4th quartile of the "Healthy" pattern scores had higher odds of MHOv/O as compared to those in the 1st quartile (OR: 4.04, CI:1.26-13.01). Conclusions The findings of this study provided evidence on the combined effect of lifestyle factors in relation to cardiometabolic abnormalities that are complex and multifactorial in nature. The results highlighted the importance of focusing on 'holistic' lifestyle patterns modifications in designing and implementing culturally sensitive interventions in overweight and obese subjects. Funding Sources Lebanese National Council for Scientific Research; University Research Board at the American University of Beirut); Medical Practice Plan at the American University of Beirut.

Evidence-based Complementary and Alternative Medicine, 2015

Nutrients

Knee osteoarthritis (KOA) is one of the most common joint diseases, especially in individuals wit... more Knee osteoarthritis (KOA) is one of the most common joint diseases, especially in individuals with obesity. Another condition within this population, and which presents frequently, is sarcopenic obesity (SO), defined as an increase in body fat and a decrease in muscle mass and strength. The current paper aims to describe recent nutritional strategies which can generally improve KOA clinical severity and, at the same time, ameliorate SO indices. Searches were carried out in the PubMed and Science Direct databases and data were summarized using a narrative approach. Certain key findings have been revealed. Firstly, the screening and identification of SO in patients with KOA is important, and to this end, simple physical performance tests and anthropometric measures are available in the literature. Secondly, adherence to a Mediterranean diet and the achievement of significant body weight loss by means of low-calorie diets (LCDs) remain the cornerstone nutritional treatment in this popu...

Clinics and Practice

Little remains known regarding the impact of weight loss on sarcopenic obesity (SO), and for this... more Little remains known regarding the impact of weight loss on sarcopenic obesity (SO), and for this reason we aimed to assess the relationship between the two during a weight management program. Body composition was measured at baseline and six-month follow-up using the Tanita BC-418, and step measurements were obtained daily over a period of six months using an Omron HJ-320 pedometer, in 41 adults of both genders with obesity. The participants were then categorized according to the presence or absence of SO. After a significant weight loss, an improvement in the appendicular skeletal mass (ASM) to weight ratio (24.5 ± 3.5 vs. 26.2 ± 3.6, p < 0.01), indicated a decrease in the prevalence of SO by 12.2%. Moreover, these findings were confirmed by logistic regression analysis revealing a significant WL% ≥ 5% combined with an active lifestyle (i.e., ≥8000 steps/day), decreased the risk of SO by 91% (OR = 0.09; 95% CI: 0.02–0.56), after adjusting for age and gender. In conclusion, in a...

Nutrients

Normal-weight obesity (NWO) is a phenotype characterized by excessive body fat (BF) despite norma... more Normal-weight obesity (NWO) is a phenotype characterized by excessive body fat (BF) despite normal body weight. We aimed to assess the association between NWO and the risk of sarcopenia. Two groups of patients with a normal body mass index [BMI (20–24.9 kg/m2)] were selected from a large cohort of participants. Body composition was measured using dual-energy X-ray absorptiometry (DXA), and 748 participants were categorized as NWO or normal-weight without obesity (NWNO) and were classed according to whether or not they were at risk of sarcopenia. The “NWO group” included 374 participants (cases), compared to 374 participants (controls) in the “NWNO group”, all of a similar BMI, age and gender. The participants in the “NWO group” displayed a higher prevalence of the risk of sarcopenia than the control group across both genders (0.6% vs. 14.1% in males; 1.4% vs. 36.5% in females). Regression analysis showed that being in the NWO category increased the risk of sarcopenia 22-fold in male...

Nutrients

Obesity is a major health problem defined as an excess accumulation of body fat (BF). The World H... more Obesity is a major health problem defined as an excess accumulation of body fat (BF). The World Health Organization (WHO) usually relies on a body mass index (BMI) ≥ 30 kg/m2 as an indicator of obesity. Due to changes in body composition that occur across the lifespan, with an increase in BF and a decrease in lean mass, we aimed to test the validity of this BMI cut-off point for adiposity in middle-aged and older adults. This cross-sectional study, composed of 4800 adults of mixed gender aged between 40 and 80 years, included (according to the WHO BMI classification) 1087 normal-weight, 1826 overweight, and 1887 obese individuals who were referred to the Department of Biomedicine and Prevention, University of Rome “Tor Vergata”, Italy. The sample was then categorized by adiposity status based on the total BF% as measured by dual-energy X-ray absorptiometry (DXA), and the best sensitivity and specificity were attained for predicting obesity according to the receiver operating charact...

Healthcare

This paper presents a review of the available literature on sarcopenic obesity (SO) in young and ... more This paper presents a review of the available literature on sarcopenic obesity (SO) in young and middle-aged female adults with obesity in weight management settings. A literature review using the PubMed/Medline and Science Direct databases was conducted, and the data were summarized through a narrative approach. Firstly, some physical performance tests and questionnaires are available for screening young and middle-aged female adults with a high risk of SO. Secondly, these patients can undergo instrumental measurements such as dual-energy X-ray absorptiometry (DXA) and bioelectrical impedance analysis (BIA) to confirm or reject a diagnosis of SO, applying definitions that account for body mass. Thirdly, SO is a prevalent phenotype in females seeking weight management treatment, as well as being strongly associated (vs. non-SO) with obesity-related comorbidities that need to be promptly managed, initially with nutritional programs or/and in combination with medications. Finally, pat...

Nutrients

It is unclear whether weight loss (WL) achieved by means of lifestyle interventions (LSIs) before... more It is unclear whether weight loss (WL) achieved by means of lifestyle interventions (LSIs) before bariatric surgery (BS) can improve long-term WL outcomes after surgery. We aimed to assess the impact of a structured LSI on WL% after gastric bypass (GBP). Two groups of patients were selected from a large cohort of participants with obesity who underwent GBP surgery at Santa Maria Nuova Hospital (Reggio Emilia, Italy). The groups were categorized as those who have or have not received LSI prior to GBP. The LSI group included 91 participants (cases) compared to 123 participants (controls) in the non-LSI group. WL% was measured at follow-up times of 1, 3, 6, 12, 24, 36, 48, and 60 months. The LSI group achieved a clinically significant WL% (−7.5%) before BS, and at the time of surgery, the two groups had similar body weights and demographic statuses. At all points, until the 24-month follow-up, the two groups displayed similar WLs%. With regard to the longer follow-ups, the LSI group ma...

Frontiers in Nutrition, 2021

Additional file 1. Food groups and the corresponding items included in the dietary patterns analy... more Additional file 1. Food groups and the corresponding items included in the dietary patterns analysis.

Background & Aim: Health-Related Quality of Life (HRQoL) is an important outcome that reflectsthe... more Background & Aim: Health-Related Quality of Life (HRQoL) is an important outcome that reflectsthe impact of chronic diseases on patients’ wellbeing. There is a paucity of studies on HRQoL and obesity in Arabspeaking countries. Therefore we aimed to investigate this outcome in this population. METHODS: The HRQoL was assessed by the validated Arabic version of the ORWELL 97 questionnaire in 116 seekingtreatment patients with obesity referred to the Nutritional and Weight management outpatient clinic of Beirut Arab University (BAU) in Lebanon, matched by age and gender to 116 normal-weight participants. RESULTS: Patients with obesity displayed higher total ORWELL 97 scores when compared with normalweight controls (52.16 ± 33.34 vs. 13.04 ± 11.36, p < 0.001), and linear regression analysis showed that the increase of Body Mass Index (BMI) among patients with obesity is associated with an increase of ORWELL 97 scores (β= 1.790, 95% CI= 0.808 2.772, p < 0.001). Moreover, the logisti...

World Academy of Science, Engineering and Technology, International Journal of Medical and Health Sciences, 2015

European Journal of Public Health, 2016

European Journal of Nutrition, 2011

Current developments in nutrition, Jun 1, 2019

Objectives The study aims to identify lifestyle patterns in a sample of Lebanese adults and exami... more Objectives The study aims to identify lifestyle patterns in a sample of Lebanese adults and examine the association of these patterns with Metabolically Healthy Overweight and Obesity (MHOv/O). Methods This study is based on a cross-sectional survey of Lebanese adults living in Greater Beirut area (n = 305), and which was conducted in 2014. Dietary intake assessment was performed using an 80-item semi-quantitative food frequency questionnaire. The identification of MHOv/O was based on the ATP-III criteria. Principal Component Factor Analysis was implemented to derive lifestyle patterns, including variables related to dietary intake, eating at home, alcohol consumption, drinking water, sleeping difficulties, smoking and physical activity. Results Two lifestyle patterns were identified in the study population: the "Unhealthy" pattern which was characterized by cigarette smoking, fast food, soft drinks and alcohol consumption . Eating at home loaded negatively on this pattern. The "Healthy" lifestyle pattern was characterized by positive loadings of food groups such as milk and dairy products, fruits and vegetables. Sleeping difficulties loaded negatively on this pattern, while physical activity had a positive loading. Multiple logistic regression analyses was performed. The results showed that subjects belonging to the 4th quartile of the "Healthy" pattern scores had higher odds of MHOv/O as compared to those in the 1st quartile (OR: 4.04, CI:1.26-13.01). Conclusions The findings of this study provided evidence on the combined effect of lifestyle factors in relation to cardiometabolic abnormalities that are complex and multifactorial in nature. The results highlighted the importance of focusing on 'holistic' lifestyle patterns modifications in designing and implementing culturally sensitive interventions in overweight and obese subjects. Funding Sources Lebanese National Council for Scientific Research; University Research Board at the American University of Beirut); Medical Practice Plan at the American University of Beirut.

Evidence-based Complementary and Alternative Medicine, 2015

Nutrients

Knee osteoarthritis (KOA) is one of the most common joint diseases, especially in individuals wit... more Knee osteoarthritis (KOA) is one of the most common joint diseases, especially in individuals with obesity. Another condition within this population, and which presents frequently, is sarcopenic obesity (SO), defined as an increase in body fat and a decrease in muscle mass and strength. The current paper aims to describe recent nutritional strategies which can generally improve KOA clinical severity and, at the same time, ameliorate SO indices. Searches were carried out in the PubMed and Science Direct databases and data were summarized using a narrative approach. Certain key findings have been revealed. Firstly, the screening and identification of SO in patients with KOA is important, and to this end, simple physical performance tests and anthropometric measures are available in the literature. Secondly, adherence to a Mediterranean diet and the achievement of significant body weight loss by means of low-calorie diets (LCDs) remain the cornerstone nutritional treatment in this popu...

Clinics and Practice

Little remains known regarding the impact of weight loss on sarcopenic obesity (SO), and for this... more Little remains known regarding the impact of weight loss on sarcopenic obesity (SO), and for this reason we aimed to assess the relationship between the two during a weight management program. Body composition was measured at baseline and six-month follow-up using the Tanita BC-418, and step measurements were obtained daily over a period of six months using an Omron HJ-320 pedometer, in 41 adults of both genders with obesity. The participants were then categorized according to the presence or absence of SO. After a significant weight loss, an improvement in the appendicular skeletal mass (ASM) to weight ratio (24.5 ± 3.5 vs. 26.2 ± 3.6, p < 0.01), indicated a decrease in the prevalence of SO by 12.2%. Moreover, these findings were confirmed by logistic regression analysis revealing a significant WL% ≥ 5% combined with an active lifestyle (i.e., ≥8000 steps/day), decreased the risk of SO by 91% (OR = 0.09; 95% CI: 0.02–0.56), after adjusting for age and gender. In conclusion, in a...

Nutrients

Normal-weight obesity (NWO) is a phenotype characterized by excessive body fat (BF) despite norma... more Normal-weight obesity (NWO) is a phenotype characterized by excessive body fat (BF) despite normal body weight. We aimed to assess the association between NWO and the risk of sarcopenia. Two groups of patients with a normal body mass index [BMI (20–24.9 kg/m2)] were selected from a large cohort of participants. Body composition was measured using dual-energy X-ray absorptiometry (DXA), and 748 participants were categorized as NWO or normal-weight without obesity (NWNO) and were classed according to whether or not they were at risk of sarcopenia. The “NWO group” included 374 participants (cases), compared to 374 participants (controls) in the “NWNO group”, all of a similar BMI, age and gender. The participants in the “NWO group” displayed a higher prevalence of the risk of sarcopenia than the control group across both genders (0.6% vs. 14.1% in males; 1.4% vs. 36.5% in females). Regression analysis showed that being in the NWO category increased the risk of sarcopenia 22-fold in male...

Nutrients

Obesity is a major health problem defined as an excess accumulation of body fat (BF). The World H... more Obesity is a major health problem defined as an excess accumulation of body fat (BF). The World Health Organization (WHO) usually relies on a body mass index (BMI) ≥ 30 kg/m2 as an indicator of obesity. Due to changes in body composition that occur across the lifespan, with an increase in BF and a decrease in lean mass, we aimed to test the validity of this BMI cut-off point for adiposity in middle-aged and older adults. This cross-sectional study, composed of 4800 adults of mixed gender aged between 40 and 80 years, included (according to the WHO BMI classification) 1087 normal-weight, 1826 overweight, and 1887 obese individuals who were referred to the Department of Biomedicine and Prevention, University of Rome “Tor Vergata”, Italy. The sample was then categorized by adiposity status based on the total BF% as measured by dual-energy X-ray absorptiometry (DXA), and the best sensitivity and specificity were attained for predicting obesity according to the receiver operating charact...

Healthcare

This paper presents a review of the available literature on sarcopenic obesity (SO) in young and ... more This paper presents a review of the available literature on sarcopenic obesity (SO) in young and middle-aged female adults with obesity in weight management settings. A literature review using the PubMed/Medline and Science Direct databases was conducted, and the data were summarized through a narrative approach. Firstly, some physical performance tests and questionnaires are available for screening young and middle-aged female adults with a high risk of SO. Secondly, these patients can undergo instrumental measurements such as dual-energy X-ray absorptiometry (DXA) and bioelectrical impedance analysis (BIA) to confirm or reject a diagnosis of SO, applying definitions that account for body mass. Thirdly, SO is a prevalent phenotype in females seeking weight management treatment, as well as being strongly associated (vs. non-SO) with obesity-related comorbidities that need to be promptly managed, initially with nutritional programs or/and in combination with medications. Finally, pat...

Nutrients

It is unclear whether weight loss (WL) achieved by means of lifestyle interventions (LSIs) before... more It is unclear whether weight loss (WL) achieved by means of lifestyle interventions (LSIs) before bariatric surgery (BS) can improve long-term WL outcomes after surgery. We aimed to assess the impact of a structured LSI on WL% after gastric bypass (GBP). Two groups of patients were selected from a large cohort of participants with obesity who underwent GBP surgery at Santa Maria Nuova Hospital (Reggio Emilia, Italy). The groups were categorized as those who have or have not received LSI prior to GBP. The LSI group included 91 participants (cases) compared to 123 participants (controls) in the non-LSI group. WL% was measured at follow-up times of 1, 3, 6, 12, 24, 36, 48, and 60 months. The LSI group achieved a clinically significant WL% (−7.5%) before BS, and at the time of surgery, the two groups had similar body weights and demographic statuses. At all points, until the 24-month follow-up, the two groups displayed similar WLs%. With regard to the longer follow-ups, the LSI group ma...

Frontiers in Nutrition, 2021

Additional file 1. Food groups and the corresponding items included in the dietary patterns analy... more Additional file 1. Food groups and the corresponding items included in the dietary patterns analysis.

Background & Aim: Health-Related Quality of Life (HRQoL) is an important outcome that reflectsthe... more Background & Aim: Health-Related Quality of Life (HRQoL) is an important outcome that reflectsthe impact of chronic diseases on patients’ wellbeing. There is a paucity of studies on HRQoL and obesity in Arabspeaking countries. Therefore we aimed to investigate this outcome in this population. METHODS: The HRQoL was assessed by the validated Arabic version of the ORWELL 97 questionnaire in 116 seekingtreatment patients with obesity referred to the Nutritional and Weight management outpatient clinic of Beirut Arab University (BAU) in Lebanon, matched by age and gender to 116 normal-weight participants. RESULTS: Patients with obesity displayed higher total ORWELL 97 scores when compared with normalweight controls (52.16 ± 33.34 vs. 13.04 ± 11.36, p < 0.001), and linear regression analysis showed that the increase of Body Mass Index (BMI) among patients with obesity is associated with an increase of ORWELL 97 scores (β= 1.790, 95% CI= 0.808 2.772, p < 0.001). Moreover, the logisti...

World Academy of Science, Engineering and Technology, International Journal of Medical and Health Sciences, 2015

European Journal of Public Health, 2016

European Journal of Nutrition, 2011