Taqi Khan | Bahria University, karachi-pakistan (original) (raw)
Papers by Taqi Khan
Annals of Transplantation
World journal of surgery, Nov 30, 2017
Protein and peptide letters, Sep 19, 2017
Concanavalin A (Con A) immobilized on the hexagonal zinc oxide (ZnO) nanoparticles, using various... more Concanavalin A (Con A) immobilized on the hexagonal zinc oxide (ZnO) nanoparticles, using various techniques like atomic force microscopy, scanning electron microscopy and X-ray diffraction showed changes in morphology of Con A and ZnO nanoparticles. FT-IR spectroscopy confirmed the linking of Con A amino groups with ZnO nanoparticles. Con A immobilized nanoparticles in contrast to native lectin showed visible changes in hemagglutination activity as confirmed by pH dependence studies using fluorimetry. The Con A coated ZnO nanoparticles did not induce any significant damage to whole cell DNA as revealed from comet assay or plasmid DNA. Con A-immobilized nanoparticles retained the agglutination activity, this can be indicative of their potential application in detection of virus transformed and neoplastic cells. To summarize Con A immobilized on ZnO nanoparticles showed pH resistance and better hemagglutination activity. However, interestingly Con A immobilized ZnO nanoparticles show...
World journal of surgery, May 23, 2017
The left kidney (LK) is preferred by transplant surgeons, because its vein is always of good leng... more The left kidney (LK) is preferred by transplant surgeons, because its vein is always of good length and has a thick wall that enables safe suturing. On the other hand, the right renal vein is generally shorter and thinner walled, and well known for its technical difficulty during venous anastomosis, and can result in graft loss. We examined our living (LD) and deceased donor (DD) recipient data and compared the incidence of technical graft loss and early graft function in right and left kidneys. A cohort of 58 adult and pediatric recipients received an LD or DD kidney between January 2015 and December 2016. The donor and recipient data were retrieved and retrospectively analyzed. Technical graft loss was defined as graft thrombosis within the 7 days after transplant. Right kidneys (RKs) were not a risk factor for technical graft loss, and no graft was lost for technical reasons in either LD or DD transplants. Early graft function in LK and RKs was also comparable in the LD cohort, a...
International scholarly research notices, 2017
Kidney transplantation (KT) is one of the treatment options for patients with chronic kidney dise... more Kidney transplantation (KT) is one of the treatment options for patients with chronic kidney disease. The number of patients waiting for kidney transplantation is growing day by day. Various strategies have been put in place to expand the donor pool. Extended criteria donors are now accepted more frequently. Increasing number of elderly donors with age > 60 years, history of diabetes or hypertension, and clinical proteinuria are accepted as donor. Dual kidney transplantation (DKT) is also more frequently done and experience with this technique is slowly building up. DKT not only helps to reduce the number of patients on waiting list but also limits unnecessary discard of viable organs. Surgical complications of DKT are comparable to single kidney transplantation (SKT). Patient and graft survivals are also promising. This review article provides a summary of evidence available in the literature.
World journal of surgery, Nov 3, 2017
International Journal of Agricultural and Food Research, 2014
Current vascular pharmacology, 2017
Cells constantly adapt to external humoral cues like cytokines and hormones, but practically most... more Cells constantly adapt to external humoral cues like cytokines and hormones, but practically most cellular behavior is under locally guided control via cell-cell interactions. Galectins (Gals) are one of the most prominent members of the group of molecules involved in this intercellular signaling. They are the family of β-galactoside specific lectins and consist of 15 different types, each with a specific function. They play crucial role in the immune system, inflammation, wound healing and carcinogenesis. In recent times, the role of Gals in the development of cardiovascular disease (CVD) has gained attention. Gals have been reported to act ambiguously by both relieving ischemia and accelerating atherosclerosis. Atherosclerosis can ultimately lead to myocardial infarction or ischemic stroke, which are both associated with Gals. There is also a role for Gals in the development of myocarditis by their influence on inflammatory processes. Moreover, Gal acts as a biomarker for the seve...
World journal of surgery, Jan 22, 2016
The American Surgeon, Oct 1, 2002
Faced with an extreme shortage of organs transplant professionals continue to explore various str... more Faced with an extreme shortage of organs transplant professionals continue to explore various strategies to expand the donor pool. Transplantation of kidneys from older and very young donors are two such options. Although kidneys from young donors (less than 5 years of age) have been associated with a high rate of technical complications and suboptimal results, use of these kidneys en bloc has been advocated to improve the outcomes. We reviewed our experience with en bloc kidney transplantation at the University of Kentucky over the past 10 years. Between 1991 and 2000 ten patients underwent kidney transplantation using kidneys en bloc from donors <5 years age. The mean age of the donors was 2.8 years with a mean weight of 16 kg (range 13-21). Mean age of the recipients was 42 years. One patient lost the graft on day one from venous thrombosis. One patient lost the graft 7 years post-transplant from chronic rejection. All of the remaining patients are doing well with functioning grafts (mean follow-up 4.5 years; range 6 months to 10 years). Both one-year and five-year graft survival rates are 89 per cent. The present study confirms that excellent results can be achieved with kidney transplantation using kidney transplantation using kidneys en bloc from donors younger than 5 years of age.
Agricultural Reviews, 2011
IndianJournals.com - Gateway to access, disperse and preserve knowledge!
ABSTRACT Plants are most attractive biological resources because of their ability to produce a hu... more ABSTRACT Plants are most attractive biological resources because of their ability to produce a huge variety of chemical compounds, and the familiarity of production in even the most rural settings. Alkaloids, terpenoids, steroids, polyketides, phenylpropanoids and flavonoids are among the economically important compounds derived from plants. By comparison, bacteria and mammals together produce around 3000 economic natural products. Agronomic traits such as herbicide tolerance, insecticides, nematodes resistance, disease-tolerance, and delayed ripening, were initial focus of crop improvement during these days through genetic recombinant DNA technology. Among all the crop quality damaging parasites, nematode infection occupies a most significant position. In this paper, we review the status of neutraceuticals under nematode infection.
The Pakistan Journal of Surgery Gynaecology and Obstetrics, 1986
Journal of Industrial Research Technology, Sep 27, 2012
The Japanese Journal of Gastroenterological Surgery, 1995
The Japanese Journal of Gastroenterological Surgery, 1994
Urotoday International Journal, Jun 1, 2011
An appendicular mass was discovered in a 44-year-old female recipient of a living donor kidney at... more An appendicular mass was discovered in a 44-year-old female recipient of a living donor kidney at the beginning of the transplant surgery. The donor nephrectomy was put on hold while the mass was explored. A perforated appendix was found and an appendectomy was completed with suture ligation of its stump. Because all infected tissue was eliminated, we proceeded with the kidney transplant. Immunosuppression treatment was tailored to the special circumstances. Only antithymocyte globulin was used until the patient had return of bowel function. She was discharged home on regular triple immunosuppression and doing well at the 6-month follow-up examination. The incidental discovery of an appendicular mass at the time of transplant surgery may not be an absolute contraindication to immediate kidney transplantation, if the patient meets specific selection criteria.
The Pakistan Journal of Surgery Gynaecology and Obstetrics, 1989
Penetrating neck injury constitutes 5-10 % of all cases seen in the emergency room. As surgeons w... more Penetrating neck injury constitutes 5-10 % of all cases seen in the emergency room. As surgeons we must be prepared to manage these cases. After stabilizing the general condition of the patient the neck injuries are assessed. Management has changed from routine exploration to selective exploration. Injury to aerodigestive tract and vessels are commonly seen.
Annals of Transplantation
World journal of surgery, Nov 30, 2017
Protein and peptide letters, Sep 19, 2017
Concanavalin A (Con A) immobilized on the hexagonal zinc oxide (ZnO) nanoparticles, using various... more Concanavalin A (Con A) immobilized on the hexagonal zinc oxide (ZnO) nanoparticles, using various techniques like atomic force microscopy, scanning electron microscopy and X-ray diffraction showed changes in morphology of Con A and ZnO nanoparticles. FT-IR spectroscopy confirmed the linking of Con A amino groups with ZnO nanoparticles. Con A immobilized nanoparticles in contrast to native lectin showed visible changes in hemagglutination activity as confirmed by pH dependence studies using fluorimetry. The Con A coated ZnO nanoparticles did not induce any significant damage to whole cell DNA as revealed from comet assay or plasmid DNA. Con A-immobilized nanoparticles retained the agglutination activity, this can be indicative of their potential application in detection of virus transformed and neoplastic cells. To summarize Con A immobilized on ZnO nanoparticles showed pH resistance and better hemagglutination activity. However, interestingly Con A immobilized ZnO nanoparticles show...
World journal of surgery, May 23, 2017
The left kidney (LK) is preferred by transplant surgeons, because its vein is always of good leng... more The left kidney (LK) is preferred by transplant surgeons, because its vein is always of good length and has a thick wall that enables safe suturing. On the other hand, the right renal vein is generally shorter and thinner walled, and well known for its technical difficulty during venous anastomosis, and can result in graft loss. We examined our living (LD) and deceased donor (DD) recipient data and compared the incidence of technical graft loss and early graft function in right and left kidneys. A cohort of 58 adult and pediatric recipients received an LD or DD kidney between January 2015 and December 2016. The donor and recipient data were retrieved and retrospectively analyzed. Technical graft loss was defined as graft thrombosis within the 7 days after transplant. Right kidneys (RKs) were not a risk factor for technical graft loss, and no graft was lost for technical reasons in either LD or DD transplants. Early graft function in LK and RKs was also comparable in the LD cohort, a...
International scholarly research notices, 2017
Kidney transplantation (KT) is one of the treatment options for patients with chronic kidney dise... more Kidney transplantation (KT) is one of the treatment options for patients with chronic kidney disease. The number of patients waiting for kidney transplantation is growing day by day. Various strategies have been put in place to expand the donor pool. Extended criteria donors are now accepted more frequently. Increasing number of elderly donors with age > 60 years, history of diabetes or hypertension, and clinical proteinuria are accepted as donor. Dual kidney transplantation (DKT) is also more frequently done and experience with this technique is slowly building up. DKT not only helps to reduce the number of patients on waiting list but also limits unnecessary discard of viable organs. Surgical complications of DKT are comparable to single kidney transplantation (SKT). Patient and graft survivals are also promising. This review article provides a summary of evidence available in the literature.
World journal of surgery, Nov 3, 2017
International Journal of Agricultural and Food Research, 2014
Current vascular pharmacology, 2017
Cells constantly adapt to external humoral cues like cytokines and hormones, but practically most... more Cells constantly adapt to external humoral cues like cytokines and hormones, but practically most cellular behavior is under locally guided control via cell-cell interactions. Galectins (Gals) are one of the most prominent members of the group of molecules involved in this intercellular signaling. They are the family of β-galactoside specific lectins and consist of 15 different types, each with a specific function. They play crucial role in the immune system, inflammation, wound healing and carcinogenesis. In recent times, the role of Gals in the development of cardiovascular disease (CVD) has gained attention. Gals have been reported to act ambiguously by both relieving ischemia and accelerating atherosclerosis. Atherosclerosis can ultimately lead to myocardial infarction or ischemic stroke, which are both associated with Gals. There is also a role for Gals in the development of myocarditis by their influence on inflammatory processes. Moreover, Gal acts as a biomarker for the seve...
World journal of surgery, Jan 22, 2016
The American Surgeon, Oct 1, 2002
Faced with an extreme shortage of organs transplant professionals continue to explore various str... more Faced with an extreme shortage of organs transplant professionals continue to explore various strategies to expand the donor pool. Transplantation of kidneys from older and very young donors are two such options. Although kidneys from young donors (less than 5 years of age) have been associated with a high rate of technical complications and suboptimal results, use of these kidneys en bloc has been advocated to improve the outcomes. We reviewed our experience with en bloc kidney transplantation at the University of Kentucky over the past 10 years. Between 1991 and 2000 ten patients underwent kidney transplantation using kidneys en bloc from donors <5 years age. The mean age of the donors was 2.8 years with a mean weight of 16 kg (range 13-21). Mean age of the recipients was 42 years. One patient lost the graft on day one from venous thrombosis. One patient lost the graft 7 years post-transplant from chronic rejection. All of the remaining patients are doing well with functioning grafts (mean follow-up 4.5 years; range 6 months to 10 years). Both one-year and five-year graft survival rates are 89 per cent. The present study confirms that excellent results can be achieved with kidney transplantation using kidney transplantation using kidneys en bloc from donors younger than 5 years of age.
Agricultural Reviews, 2011
IndianJournals.com - Gateway to access, disperse and preserve knowledge!
ABSTRACT Plants are most attractive biological resources because of their ability to produce a hu... more ABSTRACT Plants are most attractive biological resources because of their ability to produce a huge variety of chemical compounds, and the familiarity of production in even the most rural settings. Alkaloids, terpenoids, steroids, polyketides, phenylpropanoids and flavonoids are among the economically important compounds derived from plants. By comparison, bacteria and mammals together produce around 3000 economic natural products. Agronomic traits such as herbicide tolerance, insecticides, nematodes resistance, disease-tolerance, and delayed ripening, were initial focus of crop improvement during these days through genetic recombinant DNA technology. Among all the crop quality damaging parasites, nematode infection occupies a most significant position. In this paper, we review the status of neutraceuticals under nematode infection.
The Pakistan Journal of Surgery Gynaecology and Obstetrics, 1986
Journal of Industrial Research Technology, Sep 27, 2012
The Japanese Journal of Gastroenterological Surgery, 1995
The Japanese Journal of Gastroenterological Surgery, 1994
Urotoday International Journal, Jun 1, 2011
An appendicular mass was discovered in a 44-year-old female recipient of a living donor kidney at... more An appendicular mass was discovered in a 44-year-old female recipient of a living donor kidney at the beginning of the transplant surgery. The donor nephrectomy was put on hold while the mass was explored. A perforated appendix was found and an appendectomy was completed with suture ligation of its stump. Because all infected tissue was eliminated, we proceeded with the kidney transplant. Immunosuppression treatment was tailored to the special circumstances. Only antithymocyte globulin was used until the patient had return of bowel function. She was discharged home on regular triple immunosuppression and doing well at the 6-month follow-up examination. The incidental discovery of an appendicular mass at the time of transplant surgery may not be an absolute contraindication to immediate kidney transplantation, if the patient meets specific selection criteria.
The Pakistan Journal of Surgery Gynaecology and Obstetrics, 1989
Penetrating neck injury constitutes 5-10 % of all cases seen in the emergency room. As surgeons w... more Penetrating neck injury constitutes 5-10 % of all cases seen in the emergency room. As surgeons we must be prepared to manage these cases. After stabilizing the general condition of the patient the neck injuries are assessed. Management has changed from routine exploration to selective exploration. Injury to aerodigestive tract and vessels are commonly seen.