LJ Biopunk / Genetic Engineering Community (original) (raw)
LJ Biopunk / Genetic Engineering Community [Most Recent Entries][Calendar View] [Friends]
Below are the 20 most recent journal entries recorded inBiopunk LJ Community's LiveJournal:
[ << Previous 20 ]
| Friday, July 31st, 2009 | ||||||
|---|---|---|---|---|---|---|
| _4:51 pm_[odellus] |
The Epigenetic Code How far away does everyone think we are from deciphering the epigenetic code? I ask because it is my life's work to discover it, and I am curious as to how long other people think it will take for me to find it. (1 Comment |Comment on this) | |||||
| Thursday, July 31st, 2008 | ||||||
| _7:08 am_[bitriotrecords] |
Win free gear from PreSonus and Torrent Vaccine Bit Riot Records is proud to announce: |
Producing the answer to what's next. |
||||
| Friday, May 30th, 2008 | ||||||
| _11:29 pm_[zhivoi] |
Towards to the ressurection of tasmanian tiger First step to the resurrection of Tasmanian tiger. The DNA of the extinct Tasmanian tiger (Thylacinus cynocephalus ) has been resurrected in a mouse.Tasmanian tiger Thylacinus cynocephalus is an extinct species. Last animal died at 1936 in one of the Tasmanian Zoo (Tasmania is a bg island,it belongs to Australia). A. Pask from University of Australia and his American colleagues prepated a DNA from the 100 years old alcohol-preserved Tasmanian tiger from Museum Victoria in Melbourne. Biologists managed to create gene-modified mice with the Tasmanian tiger gene called Col2a1 , which regulates the development of cartilage and bone. This extinct gene works even in mouse. This is the first time DNA from an extinct animal has been shown to have a function in another animal.However, it is so early to think about resurrection of whole animal, it is just one gene for now. Reference:1) Tasmanian tiger gene lives again. Functioning gene of extinct animal gives hope for studying long-lost species. Published online 20 May 2008 | Nature | doi:10.1038/news.2008.841 http://www.nature.com/news/2008/080520/full/news.2008.841.html2) Original research is published at PLOSResurrection of DNA Function In Vivo from an Extinct GenomeAndrew J. Pask1,2, Richard R. Behringer1*, Marilyn B. Renfree21 Department of Molecular Genetics, University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America2 Department of Zoology, University of Melbourne, Melbourne, Victoria, AustraliaPLoS ONE | www.plosone.org 1 May 2008 | Volume 3 | Issue 5 | e2240 (Comment on this) |
| Thursday, November 22nd, 2007 | ||||||
| _3:46 am_[lost_aesthete] |
Future Network News For those of you with an interest in international politics, futurism, the environment, genetic modification, Peak oil, climate change, etc please watch my new webcast showFNN - Future Network News@http://futurenetworknews.blogspot.com/leave a comment and let me know what you think.Cheers. (Comment on this) | |||||
| Tuesday, June 19th, 2007 | ||||||
| _12:36 am_[of_salfarro] |
Why Hello There I recently read and was impressed by the following article by Lee Silver when it appeared in Skeptical Inquirer the issue before last (and I enjoyed this issue's smackdown by him towards the negative mail he received regarding it).http://www.leemsilver.net/challenging/articles/2006%20NYAS/2006NYAS.html_Of course, empirical analysis is required to show that the modification does not make the meat any more harmful to human health than it would be otherwise. With modern technologies for analyzing genomes, transcriptosomes, proteomes, and metabolomes, any newly constructed transgenic animal can be analyzed in great molecular detail. "Isn't it ironic," Phillips and Forsberg commented13, "that new varieties of animals with extreme but natural mutations undergo no safety testing at all?"_I'm sure many of you may have already read it. Anyway, I was searching for more information about Lee Silver and I discovered he has a blog, and it's RSS. It doesn't seem to have been put into LJ yet, and I no longer have a paid account.. *wink wink nudge nudge* Oh aren't I so bold! ;P (Comment on this) | |||||
| Thursday, May 31st, 2007 | ||||||
| _10:37 am_[korvac] |
Studies show GM crops safer, healthier than normal crops http://www.acsh.org/factsfears/newsID.962/news_detail.aspThe best part is that the first author was my advisor in college! Small freakin world. (3 Comments |Comment on this) | |||||
| Tuesday, May 1st, 2007 | ||||||
| _10:37 am_[korvac] |
Not growing new eyes, but still cool http://news.yahoo.com/s/nm/20070501/sc_nm/blindness_genes_dc (Comment on this) | |||||
| Thursday, December 28th, 2006 | ||||||
| _5:46 am_[korvac] |
FDA scientists determine cloned food same as noncloned food http://www.denverpost.com/ci_4910171Hard to believe it but I'm posting to the community... (6 Comments |Comment on this) | |||||
| Tuesday, October 31st, 2006 | ||||||
| _4:56 pm_[the_solecist] |
Yes, but is it really artificial? UK scientists grow artificial liver_A tiny artificial liver has been grown from stem cells by Newcastle University scientists and is set to revolutionise the medical world._Rest of Article. Current Mood:  calm (2 Comments |Comment on this) |
|||||
| Thursday, October 26th, 2006 | ||||||
| _8:06 am_[the_solecist] |
Face - Off and On. First full-face transplant to be performed in UKA London surgeon has been given the go-ahead to carry out what could be the world's first full-face transplant.Rest of articleTypical if it shows up in fiction it will be pursued in real life stuff.Cool... Wearing some dead person's face = Identity Theft? This will screw with the face recognition systems being proposed for security. Current Mood: amused (Comment on this) |
|||||
| Monday, March 13th, 2006 | ||||||
| _11:54 am_[the_solecist] |
Meat Sheets! Here's one from a ways back - not really news, but when it makes it into a cartoon it's more real. |
|||||
| Thursday, November 24th, 2005 | ||||||
| _10:28 am_[immortals_good] |
HAPPY THANKSGIVING to EVERYBODY!! (Comment on this) | |||||
| Monday, October 24th, 2005 | ||||||
| _8:00 am_[korvac] |
Artificial life being created at Los Alamos? An interesting transcript of a New Scientist article.http://www.protolife.net/news/press_articles/NewScientistFeb05.pdf (Comment on this) | |||||
| Wednesday, October 19th, 2005 | ||||||
| _7:02 pm_[dankamongmen] |
better cognition through chemistry (crossposted from my main journal at  dankamongmen)Ahh, I finally think I've the time and external stability necessary to renew passionate research of and personal experimentation with nootropics (nothing pisses me off so much, every day, as the possibility that precious neuromatter upstairs is undisciplined). I've planned a high-viscosity, low-maximum cyclical regimen with minimal feedback (even single-blind objectivity seems unattainable in time-sensitive self-experimentation, sadly), varying a single psychotropic agent at each period (supplements necessitated by a psychotropic agent, such as choline, are considered part of the agent's definition with regards to control unless their noooneutrality (?) has been established. Thus, the first experiment tests "piracetam + phosphocholine"). Difficulties include assessing and adjusting for possible superpositioning (including delayed inhibition, a negative superpositioning or subpositioning if you will) of effect, the length of the agent testing period, lack of either a controlled environment or a large, representative body of test subjects. Then there's that old standby, the chance of permanent brain damage. C'est la vie! Such is the plight of the determined self-experimentalist -- it's hard to be a Man of Science in these United States, 2005. I launched my happy reimmersion into the quest for "thicker, bushier dendrites" this morning with 1g piracetam, administered via intramuscular reconstitute injection with the purpose of ceremonial pomp, followed after one half-hour with 1600mg phosphocholine administered orally. HURRY UP PLEASE IT'S TIME. I look forward to the switch to aloraracetam (piracetam is a known quantity to me, and is first to bat in the hopes a more accurate neotic / behavioral baseline might be drawn); its lower mg/kg ratio lessens my worries regarding the CNS-stim potentiating nature of racetams (amphetamine's Raid for my dopaminergic system quite enough already). I'd like very much to try phentropyl as the first non-racetam in this scheme, but it seems nearly impossible to score. Unfortunate; I enjoy the Russian brand of product engineering, one geared toward drunk bear wrestlers who cry at night over their Tolstoy and black bread, wishing their alphabet hadn't have been squashed with a tractor. I bet Rasputin would've been great to tweak with. Счастья и здоровья!Anyone in the wide world of friendslisting have suggestions or experiences to share? They'd be most appreciated. Mehums', neophobes' and bioluddites' matronly fussing should be taken somewhere else; enjoy being eclipsed on the evolutionary ladder, cockbags! Remember Tennyson: "this gray spirit yearning in desire / To follow knowledge like a sinking star / Beyond the utmost bound of human thought." There is no bound beyond the utmost, but there is humanity beyond humans; therein we must search for a new utmost bound. Current Mood: apothecarian (1 Comment |Comment on this) |
|||||
| Wednesday, October 5th, 2005 | ||||||
| _12:03 pm_[korvac] |
Hot diggety Scientists rebuild 1918 Spanish flu virushttp://www.cnn.com/2005/HEALTH/conditions/10/05/1918.flu.pandemic.ap/index.html (Comment on this) | |||||
| Tuesday, September 20th, 2005 | ||||||
| _6:56 pm_[immortals_good] |
Yi Xing and Christopher Lee * Molecular Biology Institute, Center for Genomics and Proteomics, Department of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095 Edited by Samuel Karlin, Stanford University, Stanford, CA, and approved July 1, 2005 (received for review February 11, 2005)Recently, it was proposed that alternative splicing may act as a mechanism for opening accelerated paths of evolution, by reducing negative selection pressure, but there has been little evidence so far that this mechanism could produce adaptive benefit. Here, we use metrics of very different types of selection pressures [e.g., against amino acid mutations (Ka/Ks), against mutations at synonymous sites (Ks), and for protein reading-frame preservation] to address this question by genomewide analyses of human, chimpanzee, mouse, and rat. These data show that alternative splicing relaxes Ka/Ks selection pressure up to 7-fold, but intriguingly this effect is accompanied by a strong increase in selection pressure against synonymous mutations, which propagates into the adjacent intron, and correlates strongly with the alternative splicing level observed for each exon. These effects are highly local to the alternatively spliced exon. Comparisons of these four genomes consistently show an increase in the density of amino acid mutations (Ka) in alternatively spliced exons and a decrease in the density of synonymous mutations (Ks). This selection pressure against synonymous mutations in alternatively spliced exons was accompanied in all four genomes by a striking increase in selection pressure for protein reading-frame preservation, and both increased markedly with increasing evolutionary age. Restricting our analysis to a subset of exons with strong evidence for biologically functional alternative splicing produced identical results. Thus alternative splicing apparently can create evolutionary "hotspots" within a protein sequence, and these events have evidently been selected for during mammalian evolution. (Comment on this) | |||||
| Saturday, September 17th, 2005 | ||||||
| _9:36 am_[immortals_good] |
French scientists have used mouse stem cells to repair sheep hearts in what's being hailed as a big step forward for embryonic stem cell research.The scientists, from the National Center for Scientific Research in Montpellier, France and the European Hospital Georges Pompidou in Paris, transplanted the mouse cells into nine sheep that suffered a heart attack.The cells were implanted two weeks after the attack. One month later, new heart cells were apparent and the sheep had healthier hearts than a control group that didn't get the transplant. According to a report by Reuters, an important aspect of the work is that the cells used in the study weren't completely undifferentiated but, rather, were coaxed into becoming heart cells before transplantation. Another important aspect is that there were no signs of rejection.The study is reported in The Lancet. (2 Comments |Comment on this) | |||||
| Tuesday, September 6th, 2005 | ||||||
| _3:03 pm_[korvac] |
Things that make you go 'WTF', from  lab_gripes http://www.livejournal.com/community/lab_gripes/322325.html (Comment on this) |
|||||
| Tuesday, June 28th, 2005 | ||||||
| _4:07 am_[effrenata] |
Patenting Human DNA -- What Do You Think? The US government has granted patents on human genes to private corporations."The National Institutes of Health, and others, have secured patent rights for fragmented gene sequences, many with unknown function and physical significance. This trend has enabled research institutions and corporations to secure patents for almost 5% of the entire human genome, and has spurred a rush for ownership of the remaining 95% of the human genome."From http://www.hartford-hwp.com/archives/41/024.htmlThe Human Genome Diversity project has been collecting genetic samples from world indigenous peoples. Patents have already been granted for the genes of several Native American tribes. Although sample donations were completely voluntary, participants were not informed that their genetic information would be owned by others. See these pages:http://www.ratical.org/many_worlds/6Nations/DemoningBGH.html (Liberal-biased, but contains some valid info.)http://www.organicconsumers.org/genome.htmlHere is the HGD's own website: http://www.stanford.edu/group/morrinst/hgdp/faq.htmlI think the HGD project itself is a beneficial one, but I don't approve of the patenting of human DNA sequences. Supposedly, the purpose in patenting indigenous genes is to preserve rare and endangered bloodlines. I think this idea is spurious, however. Holding a monopolistic patent on genes can enable a company to conceal information that could have crucial medical significance -- and, ironically, prevent other organizations from engaging in useful research.The first and most important property right each individual has is the right to his or her own body. Human genetic information and its potential medical uses should not be controlled by government or corporations. What do people here think about this issue? (10 Comments |Comment on this) | |||||
| Monday, May 16th, 2005 | ||||||
| _9:14 am_[the_solecist] |
Blood Powered Fuel Cells Link from lord_sauron in the cyberpunk community.New fuel cell opens way for artificial heartsTokyo - A Japanese research team has developed a fuel cell that runs on blood without using toxic substances, opening the way for use in artificial hearts and other organs.Current Mood: busy (Comment on this) |
[ << Previous 20 ]