Petros C. Mavroidis | Columbia University Law School (original) (raw)
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Papers by Petros C. Mavroidis
The basic point I advocate in this chapter is that the WTO dispute settlement system aims to curb... more The basic point I advocate in this chapter is that the WTO dispute settlement system aims to curb unilateral
punishment. Sanctions can be imposed only in accordance with the outcome of a multilateral
process that has been established in order to decide on the (il)legality of actions by WTO members, and
the legal consequences thereof. The purpose of this process is to ensure that reciprocal commitments
entered should not be unilaterally undone through the commission of illegal acts. There are good reasons
though, to doubt whether reciprocity, its statutory underpinnings notwithstanding has also been
observed in practice. The insistence on calculating remedies prospectively, and not as of the date when
an illegality has been committed, and the ensuing losses for everybody that could or could not be
symmetric lend support to the claim that the WTO regime serves “diffuse” as opposed to “specific” reciprocity.
Still, WTO members continue to routinely submit their disputes to the WTO adjudicating fora,
showing through their behavior that, if necessary, they would rather live in a world where punishment
is curbed, than in a world where punishment acts as deterrent.
World Scientific Studies in International Economics, 2013
Ssrn Electronic Journal, 2000
The Law, Economics and Politics of International Standardisation, 2000
Journal of World Trade, Feb 1, 2006
Journal of World Trade, Jun 1, 1998
Annuaire Francais De Droit International, 1996
Journal of Medical Physics, 2015
In clinical practice, evaluation of clinical efficacy of treatment planning stems from the radiat... more In clinical practice, evaluation of clinical efficacy of treatment planning stems from the radiation oncologist's experience in accurately targeting tumors, while keeping minimal toxicity to various organs at risk (OAR) involved. A more objective, quantitative method may be raised by using radiobiological models. The purpose of this work is to evaluate the potential correlation of OAR-related toxicities to its radiobiologically estimated parameters in simultaneously integrated boost (SIB) intensity modulated radiation therapy (IMRT) plans of patients with head and neck tumors at two institutions. Lyman model for normal tissue complication probability (NTCP) and the Poisson model for tumor control probability (TCP) models were used in the Histogram Analysis in Radiation Therapy (HART) analysis. In this study, 33 patients with oropharyngeal primaries in the head and neck region were used to establish the correlation between NTCP values of (a) bilateral parotids with clinically observed rates of xerostomia, (b) esophagus with dysphagia, and (c) larynx with dysphagia. The results of the study indicated a strong correlation between the severity of xerostomia and dysphagia with Lyman NTCP of bilateral parotids and esophagus, respectively, but not with the larynx. In patients without complications, NTCP values of these organs were negligible. Using appropriate radiobiological models, the presence of a moderate to strong correlation between the severities of complications with NTCP of selected OARs suggested that the clinical outcome could be estimated prior to treatment.
International journal of radiation oncology, biology, physics
Research Handbook on the WTO and Technical Barriers to Trade, 2013
SSRN Electronic Journal, 2000
Medical Physics
Purpose: To evaluate and compare the deformable image registration algorithms available in the Ve... more Purpose: To evaluate and compare the deformable image registration algorithms available in the Velocity (Velocity Medical Solutions, Atlanta, GA) and RayStation (RaySearch Americas, Inc., Garden city NY).
Medical Physics, 2015
ABSTRACT To study the frequency of Multi-Leaf Collimator (MLC) leaf failures, investigate methods... more ABSTRACT To study the frequency of Multi-Leaf Collimator (MLC) leaf failures, investigate methods to predict them and reduce linac downtime. A Varian HD120 MLC was used in our study. The hyperterminal MLC errors logged from 06/2012 to 12/2014 were collected. Along with the hyperterminal errors, the MLC motor changes and all other MLC interventions by the linear accelerator engineer were recorded. The MLC dynalog files were also recorded on a daily basis for each treatment and during linac QA. The dynalog files were analyzed to calculate root mean square errors (RMS) and cumulative MLC travel distance per motor. An in-house MatLab code was used to analyze all dynalog files, record RMS errors and calculate the distance each MLC traveled per day. A total of 269 interventions were recorded over a period of 18 months. Of these, 146 included MLC motor leaf change, 39 T-nut replacements, and 84 MLC cleaning sessions. Leaves close to the middle of each side required the most maintenance. In the A bank, leaves A27 to A40 recorded 73% of all interventions, while the same leaves in the B bank counted for 52% of the interventions. On average, leaves in the middle of the bank had their motors changed approximately every 1500m of travel. Finally, it was found that the number of RMS errors increased prior to an MLC motor change. An MLC dynalog file analysis software was developed that can be used to log daily MLC usage. Our eighteen-month data analysis showed that there is a correlation between the distance an MLC travels, the RMS and the life of the MLC motor. We plan to use this tool to predict MLC motor failures and with proper and timely intervention, reduce the downtime of the linac during clinical hours.
Medical Physics, 2015
ABSTRACT
Medical Physics
Purpose: To assess the efficacy of the BLADE technique to eliminate motion, truncation, flow and ... more Purpose: To assess the efficacy of the BLADE technique to eliminate motion, truncation, flow and other artifacts in Cervical Spine MRI compared to the conventional technique. To study the ability of the examined sequences to reduce the indetention and wrap artifacts, which have been reported in BLADE sagittal sequences.
Medical Physics, 2015
ABSTRACT The aim of this present study is to increase bandwidth (BW) and echo train length (ETL) ... more ABSTRACT The aim of this present study is to increase bandwidth (BW) and echo train length (ETL) in Proton Density Turbo Spin Echo (PD TSE) sequences with and without fat saturation (FS) as well as in Turbo Inversion Recovery Magnitude sequences (TIRM) in order to assess whether these sequences are capable of reducing susceptibility artifacts. We compared 1) TIRM coronal (COR) with the same sequence with increased both BW and ETL 2) Conventional PD TSE sagittal (SAG) with FS with an increased BW 3) Conventional PD TSE SAG without FS with an increased BW 4) Conventional PD TSE SAG without FS with increased both BW and ETL. A quantitative analysis was performed to measure the extent of the susceptibility artifacts. Furthermore, a qualitative analysis was performed by two radiologists in order to evaluate the susceptibility artifacts, image distortion and fat suppression. The depiction of cartilage, menisci, muscles, tendons and bone marrow were also qualitatively analyzed. The quantitative analysis found that the modified TIRM sequence is significantly superior to the conventional one regarding the extent of the susceptibility artifacts. In the qualitative analysis, the modified TIRM sequence was superior to the corresponding conventional one in eight characteristics out of ten that were analyzed. The modified PD TSE with FS was superior to the corresponding conventional one regarding the susceptibility artifacts, image distortion and depiction of bone marrow and cartilage while achieving effective fat saturation. The modified PD TSE sequence without FS with a high (H) BW was found to be superior corresponding to the conventional one in the case of cartilage. Consequently, TIRM sequence with an increased BW and ETL is proposed for producing images of high quality and modified PD TSE with H BW for smaller metals, especially when FS is used.
The basic point I advocate in this chapter is that the WTO dispute settlement system aims to curb... more The basic point I advocate in this chapter is that the WTO dispute settlement system aims to curb unilateral
punishment. Sanctions can be imposed only in accordance with the outcome of a multilateral
process that has been established in order to decide on the (il)legality of actions by WTO members, and
the legal consequences thereof. The purpose of this process is to ensure that reciprocal commitments
entered should not be unilaterally undone through the commission of illegal acts. There are good reasons
though, to doubt whether reciprocity, its statutory underpinnings notwithstanding has also been
observed in practice. The insistence on calculating remedies prospectively, and not as of the date when
an illegality has been committed, and the ensuing losses for everybody that could or could not be
symmetric lend support to the claim that the WTO regime serves “diffuse” as opposed to “specific” reciprocity.
Still, WTO members continue to routinely submit their disputes to the WTO adjudicating fora,
showing through their behavior that, if necessary, they would rather live in a world where punishment
is curbed, than in a world where punishment acts as deterrent.
World Scientific Studies in International Economics, 2013
Ssrn Electronic Journal, 2000
The Law, Economics and Politics of International Standardisation, 2000
Journal of World Trade, Feb 1, 2006
Journal of World Trade, Jun 1, 1998
Annuaire Francais De Droit International, 1996
Journal of Medical Physics, 2015
In clinical practice, evaluation of clinical efficacy of treatment planning stems from the radiat... more In clinical practice, evaluation of clinical efficacy of treatment planning stems from the radiation oncologist's experience in accurately targeting tumors, while keeping minimal toxicity to various organs at risk (OAR) involved. A more objective, quantitative method may be raised by using radiobiological models. The purpose of this work is to evaluate the potential correlation of OAR-related toxicities to its radiobiologically estimated parameters in simultaneously integrated boost (SIB) intensity modulated radiation therapy (IMRT) plans of patients with head and neck tumors at two institutions. Lyman model for normal tissue complication probability (NTCP) and the Poisson model for tumor control probability (TCP) models were used in the Histogram Analysis in Radiation Therapy (HART) analysis. In this study, 33 patients with oropharyngeal primaries in the head and neck region were used to establish the correlation between NTCP values of (a) bilateral parotids with clinically observed rates of xerostomia, (b) esophagus with dysphagia, and (c) larynx with dysphagia. The results of the study indicated a strong correlation between the severity of xerostomia and dysphagia with Lyman NTCP of bilateral parotids and esophagus, respectively, but not with the larynx. In patients without complications, NTCP values of these organs were negligible. Using appropriate radiobiological models, the presence of a moderate to strong correlation between the severities of complications with NTCP of selected OARs suggested that the clinical outcome could be estimated prior to treatment.
International journal of radiation oncology, biology, physics
Research Handbook on the WTO and Technical Barriers to Trade, 2013
SSRN Electronic Journal, 2000
Medical Physics
Purpose: To evaluate and compare the deformable image registration algorithms available in the Ve... more Purpose: To evaluate and compare the deformable image registration algorithms available in the Velocity (Velocity Medical Solutions, Atlanta, GA) and RayStation (RaySearch Americas, Inc., Garden city NY).
Medical Physics, 2015
ABSTRACT To study the frequency of Multi-Leaf Collimator (MLC) leaf failures, investigate methods... more ABSTRACT To study the frequency of Multi-Leaf Collimator (MLC) leaf failures, investigate methods to predict them and reduce linac downtime. A Varian HD120 MLC was used in our study. The hyperterminal MLC errors logged from 06/2012 to 12/2014 were collected. Along with the hyperterminal errors, the MLC motor changes and all other MLC interventions by the linear accelerator engineer were recorded. The MLC dynalog files were also recorded on a daily basis for each treatment and during linac QA. The dynalog files were analyzed to calculate root mean square errors (RMS) and cumulative MLC travel distance per motor. An in-house MatLab code was used to analyze all dynalog files, record RMS errors and calculate the distance each MLC traveled per day. A total of 269 interventions were recorded over a period of 18 months. Of these, 146 included MLC motor leaf change, 39 T-nut replacements, and 84 MLC cleaning sessions. Leaves close to the middle of each side required the most maintenance. In the A bank, leaves A27 to A40 recorded 73% of all interventions, while the same leaves in the B bank counted for 52% of the interventions. On average, leaves in the middle of the bank had their motors changed approximately every 1500m of travel. Finally, it was found that the number of RMS errors increased prior to an MLC motor change. An MLC dynalog file analysis software was developed that can be used to log daily MLC usage. Our eighteen-month data analysis showed that there is a correlation between the distance an MLC travels, the RMS and the life of the MLC motor. We plan to use this tool to predict MLC motor failures and with proper and timely intervention, reduce the downtime of the linac during clinical hours.
Medical Physics, 2015
ABSTRACT
Medical Physics
Purpose: To assess the efficacy of the BLADE technique to eliminate motion, truncation, flow and ... more Purpose: To assess the efficacy of the BLADE technique to eliminate motion, truncation, flow and other artifacts in Cervical Spine MRI compared to the conventional technique. To study the ability of the examined sequences to reduce the indetention and wrap artifacts, which have been reported in BLADE sagittal sequences.
Medical Physics, 2015
ABSTRACT The aim of this present study is to increase bandwidth (BW) and echo train length (ETL) ... more ABSTRACT The aim of this present study is to increase bandwidth (BW) and echo train length (ETL) in Proton Density Turbo Spin Echo (PD TSE) sequences with and without fat saturation (FS) as well as in Turbo Inversion Recovery Magnitude sequences (TIRM) in order to assess whether these sequences are capable of reducing susceptibility artifacts. We compared 1) TIRM coronal (COR) with the same sequence with increased both BW and ETL 2) Conventional PD TSE sagittal (SAG) with FS with an increased BW 3) Conventional PD TSE SAG without FS with an increased BW 4) Conventional PD TSE SAG without FS with increased both BW and ETL. A quantitative analysis was performed to measure the extent of the susceptibility artifacts. Furthermore, a qualitative analysis was performed by two radiologists in order to evaluate the susceptibility artifacts, image distortion and fat suppression. The depiction of cartilage, menisci, muscles, tendons and bone marrow were also qualitatively analyzed. The quantitative analysis found that the modified TIRM sequence is significantly superior to the conventional one regarding the extent of the susceptibility artifacts. In the qualitative analysis, the modified TIRM sequence was superior to the corresponding conventional one in eight characteristics out of ten that were analyzed. The modified PD TSE with FS was superior to the corresponding conventional one regarding the susceptibility artifacts, image distortion and depiction of bone marrow and cartilage while achieving effective fat saturation. The modified PD TSE sequence without FS with a high (H) BW was found to be superior corresponding to the conventional one in the case of cartilage. Consequently, TIRM sequence with an increased BW and ETL is proposed for producing images of high quality and modified PD TSE with H BW for smaller metals, especially when FS is used.