HOD Chemistry | B.S.ABDUR RAHAMAN UNIVERSITY (original) (raw)

Papers by HOD Chemistry

Inorganic Chemistry Communications

An entry from the Cambridge Structural Database, the world's repository for small molecule cr... more An entry from the Cambridge Structural Database, the world's repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

International Journal of Biological Macromolecules, 2018

We used the condensation chemistry with anthracene 9 carbaldehyde and 3,4 diaminopyridine to form... more We used the condensation chemistry with anthracene 9 carbaldehyde and 3,4 diaminopyridine to form Schiff base (SB) ligand, N 2 ,N 3 bis (anthracen 9 ylmethylene) pyridine 3,4 diamine incorporating Er, Pr and Yb rare earth metals to form a series of SB complexes. Surface, structure, thermal, and optical properties of the resulting complexes were investigated using a variety of tools. The characteristic luminescence properties were observed after rare earth metal inclusions in SB. Antibacterial studies were performed against Bacillus subtilis, Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa in terms of zone of inhibition for SB complexes. The SB-Pr complexes showed better immune behavior against all the pathogens than the other SB metal complexes.

Scientific Reports, 2018

A Schiff base ligand (SBL), N 2 , N 3-bis (anthracen-9-ylmethylene) pyridine-2, 3-diamine, was sy... more A Schiff base ligand (SBL), N 2 , N 3-bis (anthracen-9-ylmethylene) pyridine-2, 3-diamine, was synthesized through the condensation of 2,6-diaminopyridine and anthracene-9-carbaldehyde using a 1:2 ratio. 1 H NMR spectra confirmed the observation of non-involvement aromatic carboxylic proton in SBL. A novel series of lanthanide (i.e., praseodymium (Pr), erbium (Er), and ytterbium (Yb))-based SBL metal complexes was successfully synthesized, and their functional groups were elaborately demonstrated using UV-visible, Fourier transform infrared (FT-IR), and fluorescence spectroscopy analyses. FT-IR spectral studies revealed that SBL behaved as a bidentate ligand and it was structured with metal ions by the two azomethine nitrogens. The synthesized SBL-based metal complexes were elaborately performed for cytotoxicity activity versus Vero, human breast cancer (MCF7), and cervical (HeLa) anticancer cell lines. After the innovative success of cisplatin as a medically recognized antitumor drug, medicinal chemists began interdisciplinary research on metal complexes for interaction with DNA/RNA, biomolecules, and proteins as antitumor drugs 1,2. On the other hand, the use of platinum (Pt) metal-based cisplatin drug in medicinal purposes causes numerous side effects, which remains a challenge to overcome to prepare efficient anticancer drugs 3-5. Medicinal inorganic chemistry offers an extensive possibility for the design of novel drugs based on the coordination and redox properties of metal complexes to fight against cancer 6,7. Currently, various metal complexes, including copper, lanthanum, and ruthenium, complexes, are considered as the most capable replacements for classical cisplatin-type drugs 7-17. For decades, Schiff bases have been considered important ligands due to their coordination chemistry, and they can be easily prepared and linked with a different kind of metal ions 18. Due to the existence of an amine group, analogous to the natural biological systems, Schiff bases show a crucial role in observing the conversion mechanism and racemization reaction in biological systems 19-25. Schiff bases have been used for various essential biological activities including antitumor, anti HIV, antibacterial, antifertility activities, antimosquito larval, antiinflammatory, and anticancer 26-33. Gokhale et al. 34 examined the activity of the ligand-based distorted square planar copper(II) complex, cis-[dichloro (N1-(2-benzyloxybenzylidene)pyridine-2-carboxamidrazone) copper(II)], against the human breast cancer cell line MCF-7 using the MTT method. Among the various metal complexes, lanthanide-based metal complexes have been deeply examined owing to their low poisonousness and high biological activities after bonding with ligands. In recent years, the research community has shown great interest in the synthesis of lanthanide-based complexes due to their applicability in DNA interaction and anticancer activity 35-37. Wang et al. 38 have reported a Schiff base La(III) complex prepared from kaempferol and diethylenetriamine interaction with DNA by intercalation mode and observed stronger La(III) complex binding and cleaving capacities with DNA than ligands by in vitro cytotoxic behaviors against HepG-2 cell lines and HL-60 cells (the human leukocytoma). Zaho et al. 39 have described a La(III) (N′N-bis-(1-carboxy-2-methylpropyl)-1,10-phenanthroline-2,9-dimethanamine) complex for antitumor activity in vitro against KB (human nasopharyngeal carcinoma) cells, BGC-823 (human stomach carcinoma) cells, Bel-7402 (human liver carcinoma) cells, HCT-8 (human coloadenocarcinoma) cells, and HL-60 cells. Neelima et al. 9 have screened the Schiff base ligand (SBL) and its La(III)

European Journal of Inorganic Chemistry, 2016

Silicotungstic acid (H 4 SiW 12 O 40) has been immobilized onto the mesopores of amine-functional... more Silicotungstic acid (H 4 SiW 12 O 40) has been immobilized onto the mesopores of amine-functionalized zirconia by exploitation of electrostatic interactions. The ionic grafting of silicotungstic acid was confirmed by XPS, FTIR, UV/Vis-DRS and TGA analysis. The mesoporosity of the material was confirmed through N 2 adsorption/desorption analysis. The morphology of