Brian Jack | Boston University (original) (raw)

Papers by Brian Jack

Journal of General Internal Medicine, Oct 4, 2013

Annals of global health, Mar 12, 2015

Quality of Life Research, Oct 25, 2022

Frontiers in Endocrinology, Aug 4, 2022

Public Health Research & Practice, Oct 1, 2022

BMC Complementary and Alternative Medicine, Jun 1, 2012

Diabetes, Jun 1, 2021

In recent years, a growing body of research has established that social determinants of health in... more In recent years, a growing body of research has established that social determinants of health influence the health outcomes of patients, especially those with T2DM. We developed a new patient-reported outcome (PRO) measure of an important social determinant of behavior that is specific to persons with T2DM: illness burden. Qualitative and quantitative methods informed the development of this new PRO. A literature review and semi-structured key informant interviews guided the establishment of an initial item pool. Expert and patient review, reading level assessment (to ensure no item had >5th grade reading-level language), and a translatability review were all used to refine the original item pool to 47 items. The refined item pool was then tested in 225 patients with T2DM. No items had sparse response option cells or problems with monotonicity; two items were deleted due to low item-rest correlations. Factor analyses (exploratory and confirmatory) supported the retention of 29 items. With those 29 remaining items, a constrained (common slope) graded response model (GRM) fit assessment indicated that two items had misfit and were excluded. No items displayed differential item functioning by age, sex, education, or socio-economic status. Thus, the final item bank is comprised of 27 items. Psychometric considerations (based on item information values) were used, in conjunction with expert content review, to select a 6-item static short form. IRT-based item parameters were employed to make this new measure available as a computer adaptive test. Internal consistency of the new PRO was excellent (α ≥ .90 for all administration formats). The new Illness Burden item bank captures patients’ perceptions of the impact that having T2DM has on their daily lives. It can be used in conjunction with the broader measurement system, the Re-Engineered Discharge for Diabetes Computer Adaptive Test, to evaluate important social determinants of behavior in persons with T2DM. Disclosure S. Mitchell: Other Relationship; Self; See Yourself Health LLC, Speaker’s Bureau; Self; Merck Sharp & Dohme Corp. M. A. Kallen: None. A. Bragg: None. I. Moldovan: None. J. M. Howard: None. B. W. Jack: None. J. A. Miner: None. C. M. Graves: None. N. Carlozzi: None. Funding National Institute of Diabetes and Digestive and Kidney Diseases (1R21DK121092)

Diabetes, Jun 1, 2021

Over 27 million Americans have type 2 diabetes mellitus (T2DM), accounting for >7.... more Over 27 million Americans have type 2 diabetes mellitus (T2DM), accounting for >7.7 million hospital admissions. Social determinants of behavior, including medication adherence, play a critical role in their health outcomes. We developed a new patient-reported outcome (PRO) measure to evaluate medication adherence in people with T2DM, using established measurement development standards. An item pool was created that reflected important content related to medication adherence for people with T2DM. The item pool was then refined, using feedback from experts, a reading-level assessment (ensuring no >5th grade reading-level content was included), a translatability review (e.g., to allow future measure translation into Spanish), and feedback from T2DM patients. Next, 225 people with T2DM completed 58 self-report medication adherence items. Exploratory factor analysis supported the item pool’s essential unidimensionality. Five items were excluded due to low item-rest correlations. Confirmatory factor analysis supported retaining 27 items. All items fit the graded response model, and no items had meaningful differential item functioning for the factors age, sex, education, or socioeconomic status. The final item bank is comprised of 27 items and can be administered as a computer adaptive test or 6- item short form. Internal consistency reliability was excellent for all administration formats (α’s all ≥ .90). The new Medication Adherence item bank provides a reliable, content-relevant assessment of medication adherence for people with T2DM. It is part of the comprehensive Re-Engineered Discharge for Diabetes Computer Adaptive Test (REDD-CAT) measurement system, which is designed to capture important social determinants of behavior for people with T2DM. Work is underway to establish additional psychometric properties (e.g., test-retest reliability, validity) of this new measure. Disclosure S. Mitchell: Other Relationship; Self; See Yourself Health LLC, Speaker’s Bureau; Self; Merck Sharp & Dohme Corp. M. A. Kallen: None. A. Bragg: None. I. Moldovan: None. J. M. Howard: None. B. W. Jack: None. J. A. Miner: None. C. M. Graves: None. N. Carlozzi: None. Funding National Institute of Diabetes and Digestive and Kidney Diseases (R21DK121092)

BMC Health Services Research, 2017

Journal of Human Growth and Development, Oct 15, 2020

PubMed, Aug 15, 2003

Family physicians (FPs) provided 30 percent of inpatient newborn care in Maine in the year 2000. ... more Family physicians (FPs) provided 30 percent of inpatient newborn care in Maine in the year 2000. FPs cared for a large proportion of newborns, especially those insured by Medicaid and in smaller, rural hospitals where FPs also delivered babies. Family medicine's commitment to serve vulnerable populations of newborns requires continued federal, state, and institutional support for training and development of future FPs.

Seminars in Reproductive Medicine, May 16, 2022

Preconception care (PCC) involves a wide-ranging set of interventions to optimize health prior to... more Preconception care (PCC) involves a wide-ranging set of interventions to optimize health prior to pregnancy. These interventions seek to enhance conception rates, pregnancy outcomes, childhood health, and the health of future generations. To assist health care providers to exercise high-quality clinical care in this domain, clinical practice guidelines from a range of settings have been published. This systematic review sought to identify existing freely accessible international guidelines, assess these in terms of their quality using the AGREE II tool, and assess the summary recommendations and the evidence level on which they are based. We identified 11 guidelines that focused on PCC. Ten of these were classified as moderate quality (scores ranging from 3.5 to 4.5 out of 7) and only one was classified as very high quality, scoring 6.5. The levels of evidence for recommendations ranged from the lowest possible level of evidence (III) to the highest (I-a): the highest quality evidence available is for folic acid supplementation to reduce risk of neural tube defects and the role of antiviral medication to prevent HIV transmission. This systematic review identified that high-quality guidelines on PCC are lacking and that few domains of PCC recommendations are supported by high-quality evidence.

American Journal of Obstetrics and Gynecology, Dec 1, 2008

American Journal of Obstetrics and Gynecology, Dec 1, 2008

Pediatrics, Jul 1, 1998

Objective. To explore the association between adequacy of prenatal care utilization and subsequen... more Objective. To explore the association between adequacy of prenatal care utilization and subsequent pediatric care utilization. Design. A longitudinal follow-up of a nationally representative sample of infants born in 1988. Participants. Nine thousand four hundred forty women who had a live birth in 1988, and whose child was alive at the time of interview, and 8285 women from the original sample who were reinterviewed in 1991. Main Outcome Measure. There were four outcome measures: number of well-child visits; adequate immunization for diphtheria, tetanus, and pertussis; adequate immunization for polio; and continuity of a regular source of care, as measured by the number of sites for pediatric care. Results. Children whose mothers had less than adequate prenatal care utilization had significantly fewer well-child visits, and were significantly less likely to have adequate immunizations, even after income, health insurance coverage, content of prenatal care, wantedness of child, sites of prenatal and pediatric care, and maternal and pregnancy risk characteristics were taken into account. Less than adequate prenatal care utilization was not associated with having more than one pediatric care site. Conclusions. Prenatal care utilization can be used to identify and target interventions to women who are at risk for not obtaining well-child care or complete immunizations for their children.

American Journal of Obstetrics and Gynecology, Dec 1, 2008

Journal of General Internal Medicine, Oct 4, 2013

Annals of global health, Mar 12, 2015

Quality of Life Research, Oct 25, 2022

Frontiers in Endocrinology, Aug 4, 2022

Public Health Research & Practice, Oct 1, 2022

BMC Complementary and Alternative Medicine, Jun 1, 2012

Diabetes, Jun 1, 2021

In recent years, a growing body of research has established that social determinants of health in... more In recent years, a growing body of research has established that social determinants of health influence the health outcomes of patients, especially those with T2DM. We developed a new patient-reported outcome (PRO) measure of an important social determinant of behavior that is specific to persons with T2DM: illness burden. Qualitative and quantitative methods informed the development of this new PRO. A literature review and semi-structured key informant interviews guided the establishment of an initial item pool. Expert and patient review, reading level assessment (to ensure no item had >5th grade reading-level language), and a translatability review were all used to refine the original item pool to 47 items. The refined item pool was then tested in 225 patients with T2DM. No items had sparse response option cells or problems with monotonicity; two items were deleted due to low item-rest correlations. Factor analyses (exploratory and confirmatory) supported the retention of 29 items. With those 29 remaining items, a constrained (common slope) graded response model (GRM) fit assessment indicated that two items had misfit and were excluded. No items displayed differential item functioning by age, sex, education, or socio-economic status. Thus, the final item bank is comprised of 27 items. Psychometric considerations (based on item information values) were used, in conjunction with expert content review, to select a 6-item static short form. IRT-based item parameters were employed to make this new measure available as a computer adaptive test. Internal consistency of the new PRO was excellent (α ≥ .90 for all administration formats). The new Illness Burden item bank captures patients’ perceptions of the impact that having T2DM has on their daily lives. It can be used in conjunction with the broader measurement system, the Re-Engineered Discharge for Diabetes Computer Adaptive Test, to evaluate important social determinants of behavior in persons with T2DM. Disclosure S. Mitchell: Other Relationship; Self; See Yourself Health LLC, Speaker’s Bureau; Self; Merck Sharp & Dohme Corp. M. A. Kallen: None. A. Bragg: None. I. Moldovan: None. J. M. Howard: None. B. W. Jack: None. J. A. Miner: None. C. M. Graves: None. N. Carlozzi: None. Funding National Institute of Diabetes and Digestive and Kidney Diseases (1R21DK121092)

Diabetes, Jun 1, 2021

Over 27 million Americans have type 2 diabetes mellitus (T2DM), accounting for >7.... more Over 27 million Americans have type 2 diabetes mellitus (T2DM), accounting for >7.7 million hospital admissions. Social determinants of behavior, including medication adherence, play a critical role in their health outcomes. We developed a new patient-reported outcome (PRO) measure to evaluate medication adherence in people with T2DM, using established measurement development standards. An item pool was created that reflected important content related to medication adherence for people with T2DM. The item pool was then refined, using feedback from experts, a reading-level assessment (ensuring no >5th grade reading-level content was included), a translatability review (e.g., to allow future measure translation into Spanish), and feedback from T2DM patients. Next, 225 people with T2DM completed 58 self-report medication adherence items. Exploratory factor analysis supported the item pool’s essential unidimensionality. Five items were excluded due to low item-rest correlations. Confirmatory factor analysis supported retaining 27 items. All items fit the graded response model, and no items had meaningful differential item functioning for the factors age, sex, education, or socioeconomic status. The final item bank is comprised of 27 items and can be administered as a computer adaptive test or 6- item short form. Internal consistency reliability was excellent for all administration formats (α’s all ≥ .90). The new Medication Adherence item bank provides a reliable, content-relevant assessment of medication adherence for people with T2DM. It is part of the comprehensive Re-Engineered Discharge for Diabetes Computer Adaptive Test (REDD-CAT) measurement system, which is designed to capture important social determinants of behavior for people with T2DM. Work is underway to establish additional psychometric properties (e.g., test-retest reliability, validity) of this new measure. Disclosure S. Mitchell: Other Relationship; Self; See Yourself Health LLC, Speaker’s Bureau; Self; Merck Sharp & Dohme Corp. M. A. Kallen: None. A. Bragg: None. I. Moldovan: None. J. M. Howard: None. B. W. Jack: None. J. A. Miner: None. C. M. Graves: None. N. Carlozzi: None. Funding National Institute of Diabetes and Digestive and Kidney Diseases (R21DK121092)

BMC Health Services Research, 2017

Journal of Human Growth and Development, Oct 15, 2020

PubMed, Aug 15, 2003

Family physicians (FPs) provided 30 percent of inpatient newborn care in Maine in the year 2000. ... more Family physicians (FPs) provided 30 percent of inpatient newborn care in Maine in the year 2000. FPs cared for a large proportion of newborns, especially those insured by Medicaid and in smaller, rural hospitals where FPs also delivered babies. Family medicine's commitment to serve vulnerable populations of newborns requires continued federal, state, and institutional support for training and development of future FPs.

Seminars in Reproductive Medicine, May 16, 2022

Preconception care (PCC) involves a wide-ranging set of interventions to optimize health prior to... more Preconception care (PCC) involves a wide-ranging set of interventions to optimize health prior to pregnancy. These interventions seek to enhance conception rates, pregnancy outcomes, childhood health, and the health of future generations. To assist health care providers to exercise high-quality clinical care in this domain, clinical practice guidelines from a range of settings have been published. This systematic review sought to identify existing freely accessible international guidelines, assess these in terms of their quality using the AGREE II tool, and assess the summary recommendations and the evidence level on which they are based. We identified 11 guidelines that focused on PCC. Ten of these were classified as moderate quality (scores ranging from 3.5 to 4.5 out of 7) and only one was classified as very high quality, scoring 6.5. The levels of evidence for recommendations ranged from the lowest possible level of evidence (III) to the highest (I-a): the highest quality evidence available is for folic acid supplementation to reduce risk of neural tube defects and the role of antiviral medication to prevent HIV transmission. This systematic review identified that high-quality guidelines on PCC are lacking and that few domains of PCC recommendations are supported by high-quality evidence.

American Journal of Obstetrics and Gynecology, Dec 1, 2008

American Journal of Obstetrics and Gynecology, Dec 1, 2008

Pediatrics, Jul 1, 1998

Objective. To explore the association between adequacy of prenatal care utilization and subsequen... more Objective. To explore the association between adequacy of prenatal care utilization and subsequent pediatric care utilization. Design. A longitudinal follow-up of a nationally representative sample of infants born in 1988. Participants. Nine thousand four hundred forty women who had a live birth in 1988, and whose child was alive at the time of interview, and 8285 women from the original sample who were reinterviewed in 1991. Main Outcome Measure. There were four outcome measures: number of well-child visits; adequate immunization for diphtheria, tetanus, and pertussis; adequate immunization for polio; and continuity of a regular source of care, as measured by the number of sites for pediatric care. Results. Children whose mothers had less than adequate prenatal care utilization had significantly fewer well-child visits, and were significantly less likely to have adequate immunizations, even after income, health insurance coverage, content of prenatal care, wantedness of child, sites of prenatal and pediatric care, and maternal and pregnancy risk characteristics were taken into account. Less than adequate prenatal care utilization was not associated with having more than one pediatric care site. Conclusions. Prenatal care utilization can be used to identify and target interventions to women who are at risk for not obtaining well-child care or complete immunizations for their children.

American Journal of Obstetrics and Gynecology, Dec 1, 2008