Jayarama Reddy | Bangalore University (original) (raw)
Papers by Jayarama Reddy
World Journal of Advance Healthcare Research, Apr 8, 2005
Applied Cell Biology
Botanical drugs or Natural drugs are medicines which are composed of natural substances, having c... more Botanical drugs or Natural drugs are medicines which are composed of natural substances, having constituents of both medicinal activities and health-enhancing properties. Medicinal potential in these plants remain un-accessed due to a plethora of reasons. With sufficient investment, the entire infrastructure of global botanical drugs can be upgraded. The plant Saraca asoca (Roxb.), Wild belongs to Caesalpiniaceae family. The data in this article can be useful in understanding the various phytochemicals present in the bark, stem, flower and seeds. The tree’s extracts are numerous and can be extracted by Gas Chromatography - Mass Chromatography (GC-MC), High Performance thin layer chromatography (HPTLC) and Soxhlet. The study shows us these extracts have many medicinal properties and abilities that can be used to treat different diseases in all the functioning systems of the body. The future study of herbal plants is crucial to improve medicinal care so that botanical plants can be us...
Saudi Journal of Pathology and Microbiology
A study was conducted for the isolation and identification of soil micro-flora in rhizosphere of ... more A study was conducted for the isolation and identification of soil micro-flora in rhizosphere of B. racemosa (L.) Spreng and R. serpentine (L.) Benth. ex Kurz, trees from Western Ghats region of Uttar Kannada, Karnataka, India. Soil samples were collected from rhizosphere of B. racemosa and R. serpentine plants, during the months of February 2022. Soil microbes were isolated by using soil dilution technique. The total number of bacteria isolated from B. racemose and R. serpentinais rhizosphere is 2,666,600 and 4,461,160 per gram of soil respectively. The rhizospheric fungal isolates present in B. racemosa and R. serpentina plants is 3,281,200 and 1,946,200 per gram of soil respectively. In B. racemosa rhizosphere, the percentage contribution is Penicillium sp with 13.679%, In R. serpentine rhizosphere, the highest percentage contribution is Cladosporium sp., Trichoderma sp.with17.663% and 17.391% respectively. In rhizosphere of B. racemose, 19 different species belonging to 15 gener...
PARIPEX INDIAN JOURNAL OF RESEARCH, 2022
Moringa oleifera, is a highly potent medicinal plant which is evergreen or deciduous in nature an... more Moringa oleifera, is a highly potent medicinal plant which is evergreen or deciduous in nature and it is found growing predominantly in the Sub-Himalayan regions of India, Pakistan, Bangladesh and Afghanistan. This plant is tagged as a medicinal plant because it contains various properties such as high antioxidant properties, anti- inflammatory, anticancer, antidiabetic and antimicrobial properties. This review paper will highlight, focus and discuss the antioxidant properties possessed by Moringa oleifera supported by some experiments containing materials required, methods employed, results procured and discussion to support the evidences that prove the antioxidant properties found in this plant. The first and the second experiment is about the presence of flavonoid contents like Quercetin and Rutin found respectively that contributes to the antioxidant properties found in the plant of subject, Moringa oleifera. While, the third experiment is based on the application of the antioxi...
PARIPEX INDIAN JOURNAL OF RESEARCH, 2022
From patients with a poor prognosis of pregnancy, 1620 embryos generated in vitro and chromosomal... more From patients with a poor prognosis of pregnancy, 1620 embryos generated in vitro and chromosomal analysis was performed on these embryos. The result was yielded in 1596 embryos, out of them 536(34%) were euploid and 1060(66%) carried chromosomal abnormalities. In addition, 92% of embryos with multinucleated cells were diagnosed mosaics whereas the 86% of chromosomal abnormalities were associated to the presence of cytoplasmic concentration. For the derivation of the normal embryonic stem cell (ESC)lines and developmental modelling aneuploid embryos have been used. Genetic diagnosis at the cleavage or blastocyst stage could be partly abnormal because during the preimplantation diploid- aneuploid mosaic embryos was most frequently observed. From a single cell of a particular embryo the chromosomal status of that embryo can be determined, thus the prevalence of mosaicism. Detection of aneuploidy in single cells have been developed recently. After conducting research methods, it was co...
South Asian journal of experimental biology, Sep 7, 2015
World Journal of Pharmaceutical Sciences, 2022
This study sought to utilize indigenous soil microorganisms to suppress wilt-causing fungal patho... more This study sought to utilize indigenous soil microorganisms to suppress wilt-causing fungal pathogens of the banana. Fungal pathogens were isolated from wilt-affected rhizospheric soil, and potential antagonistic bacterial strains were isolated from healthy rhizospheric soil in the same area from which fungal pathogens were isolated. The antifungal activity of isolated microorganisms against fungal pathogens was studied both in vitro and in vivo against fungal pathogens. It was found that Fusarium oxysporum and Alternaria sp. were pathogenic, while Penicillium sp. Bacillus velezensis and Bacillus subtilis were antagonistic. Moreover, it was seen that B. velezensis, B. subtilis and Penicillium sp. Inhibited the growth of the two fungal pathogens in both in vitro and in vivo experiments. An antagonistic consortium isolated in this study has demonstrated remarkable potential for controlling fungal diseases caused by Fusarium sp. and Alternaria sp. Therefore, the use of indigenous microflora to improve disease suppression of banana plants against soil-borne pathogens is a preferable approach.
Vitiligo is a skin disorder that has been known for at least 5000 years, but it is still incomple... more Vitiligo is a skin disorder that has been known for at least 5000 years, but it is still incompletely understood. It is considered to be a multifactorial polygenic disorder with a complex pathogenesis, linked with both genetic and non-genetic factors. It has baffled the medical world for centuries. It is a psychologically devastating clinical conundrum which affects all types of human races without any specificity and its incidences of occurrence have been rising alarmingly. Vitiligo is generally associated with a high psychiatric morbidity. The worldwide population prevalence of vitiligo ranges from 1% to 4% and shows a wide variability among ethnic groups. In India, the incidence of vitiligo has been reported to be between 1-2%. This paper reports the survey on the prevalence of vitiligo in Bangalore (India). The prevalence was found to be Vitiligo is 0.71%. A total of 22037 people were contacted in the survey cutting across all segments of the society. A total of 160 people were ...
A comparative evaluation of the antidiabetic and hypoglycaemic potential of the extracts from dif... more A comparative evaluation of the antidiabetic and hypoglycaemic potential of the extracts from different plant parts of Musa paradisiaca (MP) was carried out in vitro. MP extracts were prepared sequentially with methanol, chloroform and petroleum ether. A comparison was made between the action of extracts from different parts. Different concentrations of each extract were made by using phosphate buffer and subjected to αamylase and α-glucosidase inhibitory assays using maltose and 2-Chloro-4-Nitrophenyl-α-Maltotrioside as substrates respectively. Using this method, the percentage of α-amylase inhibitory activities of each extract were calculated. The enzymes were extracted from the sheep intestines. The absorbencies ware read at 595 nm and 405nm respectively using spectrophotometer. Methanol extracts were found to show higher inhibition. It was found that fruit and stem extract showed high rate of inhibition. At 100 μg/ml concentration of the stem extract a high of 83% inhibition of ...
The Open Drug Discovery Journal, 2010
The study was carried out to ascertain anti asthmatic, analgesic and anti convulsant activities o... more The study was carried out to ascertain anti asthmatic, analgesic and anti convulsant activities of the medicinal plant Bryonia Laciniosa . The anti asthmatic activity was estimated by mesenteric mast cell count by Atopic allergy method. Eddy's hot plate and Analgesiometer tests were used to assess the analgesic activity of Bryonia Laciniosa . Anticonvulsant activity was evaluated by Maximum electroshock- induced seizure test. The results indicated that 70% alcoholic extract of Bryonia laciniosa increased the antiasmatic activity, analgestic activity and also anticonvulsant activity. Keywords: Bryonia Laciniosa , Atopic allergy method, Eddy's hot plate analgesio meter, Electric shock method.
Objective: Insulin is used to manage diabetes mellitus by subcutaneous injections regulary, that ... more Objective: Insulin is used to manage diabetes mellitus by subcutaneous injections regulary, that has become a part of patients life and is distressing for patients. Hence, we anticipate to get rid of the usage of subcutaneous injections completely from the medicine world and would make the diabetic people to say as “farewell to painful injections.” Methods: Virtual screening method (for selection of carriers), Toxtree tool (for toxicity evaluation of carriers), and discovery studio tool (for pharmacophore designing, absorption, distribution, metabolism, excretion, and toxicity [ADMET] analysis, designing oral insulin conjugates (OICs), and interaction studies between insulin receptor and OICs) were used for proposed study. Results: We have screened 14 competent drug delivering molecules (DDMs) from seven chemical compound databases. The ADMET and pharmacophoric properties of DDMs were analyzed by drug-informatics’ tools. Consequently, the DDMs were mono, di, and poly conjugated by c...
Journal of Molecular Structure, 2013
h i g h l i g h t s Molecular and crystal structure of a simple diacid. Investigation of structur... more h i g h l i g h t s Molecular and crystal structure of a simple diacid. Investigation of structure by single crystal X-ray diffraction. Malonic acid forms continuous hydrogen bonded chains through carboxylic acid.
International Journal of Environmental Analytical Chemistry, 2006
Page 1. Intern. J. Environ. Anal. Chem. Vol. 86, No. 10, 20 August 2006, 757765 Electrochemical ... more Page 1. Intern. J. Environ. Anal. Chem. Vol. 86, No. 10, 20 August 2006, 757765 Electrochemical reduction behaviour of the synthetic pyrethroid insecticide cyfluthrin and its determination in formulations and environmental samples ...
Helvetica Chimica Acta, 2006
Both aliphatic and aromatic amino sulfonamides such as mafenide (1a) were synthesized in good yie... more Both aliphatic and aromatic amino sulfonamides such as mafenide (1a) were synthesized in good yields (80-86%) by direct electrochemical hydrogenation of the corresponding nitriles in an undivided cell containing a Ni cathode, a Pt anode, and Raney Ni as catalyst (Table 1). The reaction can be performed without external supply of pressurized gas by in situ generation of H 2. Slightly elevated temperatures (458) and low current densities (10 mA/cm 2) are favorable conditions for this type of electrochemical nitrile hydrogenation. Our synthetic protocol does not require high-pressure equipment or chemical hazards, is environmentally very friendly, and more economical than traditional methods. The concentration of adsorbed HC radicals on the catalyst surface can be easily controlled by adjusting the electric potential, which may lead to improved product selectivity and, at the same time, reduces the risk of explosion and fire. Introduction.-Amino sulfonamides are important synthetic organic compounds that often exhibit antibacterial and antifungal activities [1] [2]. Therefore, some of these compounds are called 'sulfa medicines', one example being mafenide (1a), which is being used in the treatment of acute burns [3]. The synthesis of amino sulfon-A C H T U N G T R E N N U N G amides from the corresponding nitriles by (catalytic) reduction is very important. In this process, primary amines are obtained, which form a large group of compounds widely used in pharmaceuticals and agrochemicals [4]. Nitrile reduction is also very important both in synthetic [5] and industrial [6] chemistry. Miller et al. have synthesized several amino sulfonamides by catalytic reduction of cyano compounds, nitro sulfonamides, or N-acyl derivatives [1].
Crystal Growth & Design, 2012
Transition metal complexes of the ligand 2,2′-bipyridine-4,4′-diamine (bpy4da) form three-dimensi... more Transition metal complexes of the ligand 2,2′-bipyridine-4,4′-diamine (bpy4da) form three-dimensional (3D) hydrogen bonding networks with the [M(bpy4da) 3 ] 2+ species, a hydrogen donor metallo-tecton with carboxylate counteranions as hydrogen bond acceptors within the complexes [[Ni(bpy4da) 3 ]•(Hbpc)(bpc) 0.5 (dmf) n , [Ni-(bpy4da) 3 ].(bpc)(dmf) n , and [Ni(bpy4da) 3 ]•(Htma)•4(dmf) where H 2 bpc = biphenyl-4,4′-dicarboxylic acid, H 3 tma = trimesic acid, and dmf = dimethylformamide. Terephthalate, on the other hand, bridges between Cu(II) centers in complexes [Cu 2 (bpy4da) 4 (tpa)]•2(NO 3)•5(dmf) and [Cu 2 (bpy4da) 4 (tpa)]•2(NO 3)•4.5(dmf)•(H 2 O) (where H 2 tpa = terephthalic acid) whose structures both feature different 3D hydrogen bonded networks. The crystal structures of hydrated [Cd(bpy4da) 3 ]•2Cl and [Co(bpy4da) 2 (NO 3)] 2 •2(NO 3)•4.5(dmf) are also reported.
Page 1. International Journal of Pharmaceuticals Analysis, ISSN: 0975-3079, Volume 2, Issue 2, 20... more Page 1. International Journal of Pharmaceuticals Analysis, ISSN: 0975-3079, Volume 2, Issue 2, 2010, pp-05-16 Copyright © 2010, Bioinfo Publications, International Journal of Pharmaceuticals Analysis, ISSN: 0975-3079, Volume 2, Issue 2, 2010 ...
International Journal of Agriculture Sciences, 2009
Forty two strains of Trichoderma sp. were isolated from cultivated lands around Bangalore and ana... more Forty two strains of Trichoderma sp. were isolated from cultivated lands around Bangalore and analyzed for their antagonistic potential against Sclerotium rolfsii and Fusarium ciceri. The potential of biocontrol agents ultimately lies in their capacity to control pathogens in vivo. Bioefficacy studies were hence conducted using chickpea (Cicer argentums c.v. Annigeri) as an experimental plant by the roll paper towel method. Overall the isolates T40, T35, T30 and T25 showed better antagonistic potential in addition to enhancing plant growth. The production of chitinases to break down the mycelial cell walls of fungal plant pathogens has been implicated as a major cause of biocontrol activity (Inbar and Chet, 1995). In order to study the mechanism of biocontrol, ten better performing strains were plated on media, amended with colloidal chitin and Sclerotium rolfsii cell wall extract. All the isolates showed chitinolytic activity on day three as well as day five. Production of endochitinase and exochitinase were assayed in liquid media using colloidal chitin amended broth. Strains T35 and T6 displayed maximum endochitinase and exochitinase activity. Although all strains exhibited cellulase activity, the quantum of enzyme produced was higher in T35 and T6. The results also indicate a positive correlation between enzyme production and bioefficacy.
International Journal of Environment, Agriculture and Biotechnology, 2022
Palynology is the study of pollen grain and spores. The term forensic when inserted into the pict... more Palynology is the study of pollen grain and spores. The term forensic when inserted into the picture marks the usage of pollen into a crime-solving and suspect finding tool. Pollen grain has an outer layer made up of sporopollenin which gives high durability and resistance due to which pollen can survive at adverse and extreme conditions. The samples collected from the crime scene are analysed, studied and investigated along with the samples obtained from the suspects. A relation is derived which acts as evidence during the judicial custody. Pollen analysis is highly useful if a crime that has happened long back, and now needs to be opened up. Advancement of this technique in India is still awaited.
World Journal of Advance Healthcare Research, Apr 8, 2005
Applied Cell Biology
Botanical drugs or Natural drugs are medicines which are composed of natural substances, having c... more Botanical drugs or Natural drugs are medicines which are composed of natural substances, having constituents of both medicinal activities and health-enhancing properties. Medicinal potential in these plants remain un-accessed due to a plethora of reasons. With sufficient investment, the entire infrastructure of global botanical drugs can be upgraded. The plant Saraca asoca (Roxb.), Wild belongs to Caesalpiniaceae family. The data in this article can be useful in understanding the various phytochemicals present in the bark, stem, flower and seeds. The tree’s extracts are numerous and can be extracted by Gas Chromatography - Mass Chromatography (GC-MC), High Performance thin layer chromatography (HPTLC) and Soxhlet. The study shows us these extracts have many medicinal properties and abilities that can be used to treat different diseases in all the functioning systems of the body. The future study of herbal plants is crucial to improve medicinal care so that botanical plants can be us...
Saudi Journal of Pathology and Microbiology
A study was conducted for the isolation and identification of soil micro-flora in rhizosphere of ... more A study was conducted for the isolation and identification of soil micro-flora in rhizosphere of B. racemosa (L.) Spreng and R. serpentine (L.) Benth. ex Kurz, trees from Western Ghats region of Uttar Kannada, Karnataka, India. Soil samples were collected from rhizosphere of B. racemosa and R. serpentine plants, during the months of February 2022. Soil microbes were isolated by using soil dilution technique. The total number of bacteria isolated from B. racemose and R. serpentinais rhizosphere is 2,666,600 and 4,461,160 per gram of soil respectively. The rhizospheric fungal isolates present in B. racemosa and R. serpentina plants is 3,281,200 and 1,946,200 per gram of soil respectively. In B. racemosa rhizosphere, the percentage contribution is Penicillium sp with 13.679%, In R. serpentine rhizosphere, the highest percentage contribution is Cladosporium sp., Trichoderma sp.with17.663% and 17.391% respectively. In rhizosphere of B. racemose, 19 different species belonging to 15 gener...
PARIPEX INDIAN JOURNAL OF RESEARCH, 2022
Moringa oleifera, is a highly potent medicinal plant which is evergreen or deciduous in nature an... more Moringa oleifera, is a highly potent medicinal plant which is evergreen or deciduous in nature and it is found growing predominantly in the Sub-Himalayan regions of India, Pakistan, Bangladesh and Afghanistan. This plant is tagged as a medicinal plant because it contains various properties such as high antioxidant properties, anti- inflammatory, anticancer, antidiabetic and antimicrobial properties. This review paper will highlight, focus and discuss the antioxidant properties possessed by Moringa oleifera supported by some experiments containing materials required, methods employed, results procured and discussion to support the evidences that prove the antioxidant properties found in this plant. The first and the second experiment is about the presence of flavonoid contents like Quercetin and Rutin found respectively that contributes to the antioxidant properties found in the plant of subject, Moringa oleifera. While, the third experiment is based on the application of the antioxi...
PARIPEX INDIAN JOURNAL OF RESEARCH, 2022
From patients with a poor prognosis of pregnancy, 1620 embryos generated in vitro and chromosomal... more From patients with a poor prognosis of pregnancy, 1620 embryos generated in vitro and chromosomal analysis was performed on these embryos. The result was yielded in 1596 embryos, out of them 536(34%) were euploid and 1060(66%) carried chromosomal abnormalities. In addition, 92% of embryos with multinucleated cells were diagnosed mosaics whereas the 86% of chromosomal abnormalities were associated to the presence of cytoplasmic concentration. For the derivation of the normal embryonic stem cell (ESC)lines and developmental modelling aneuploid embryos have been used. Genetic diagnosis at the cleavage or blastocyst stage could be partly abnormal because during the preimplantation diploid- aneuploid mosaic embryos was most frequently observed. From a single cell of a particular embryo the chromosomal status of that embryo can be determined, thus the prevalence of mosaicism. Detection of aneuploidy in single cells have been developed recently. After conducting research methods, it was co...
South Asian journal of experimental biology, Sep 7, 2015
World Journal of Pharmaceutical Sciences, 2022
This study sought to utilize indigenous soil microorganisms to suppress wilt-causing fungal patho... more This study sought to utilize indigenous soil microorganisms to suppress wilt-causing fungal pathogens of the banana. Fungal pathogens were isolated from wilt-affected rhizospheric soil, and potential antagonistic bacterial strains were isolated from healthy rhizospheric soil in the same area from which fungal pathogens were isolated. The antifungal activity of isolated microorganisms against fungal pathogens was studied both in vitro and in vivo against fungal pathogens. It was found that Fusarium oxysporum and Alternaria sp. were pathogenic, while Penicillium sp. Bacillus velezensis and Bacillus subtilis were antagonistic. Moreover, it was seen that B. velezensis, B. subtilis and Penicillium sp. Inhibited the growth of the two fungal pathogens in both in vitro and in vivo experiments. An antagonistic consortium isolated in this study has demonstrated remarkable potential for controlling fungal diseases caused by Fusarium sp. and Alternaria sp. Therefore, the use of indigenous microflora to improve disease suppression of banana plants against soil-borne pathogens is a preferable approach.
Vitiligo is a skin disorder that has been known for at least 5000 years, but it is still incomple... more Vitiligo is a skin disorder that has been known for at least 5000 years, but it is still incompletely understood. It is considered to be a multifactorial polygenic disorder with a complex pathogenesis, linked with both genetic and non-genetic factors. It has baffled the medical world for centuries. It is a psychologically devastating clinical conundrum which affects all types of human races without any specificity and its incidences of occurrence have been rising alarmingly. Vitiligo is generally associated with a high psychiatric morbidity. The worldwide population prevalence of vitiligo ranges from 1% to 4% and shows a wide variability among ethnic groups. In India, the incidence of vitiligo has been reported to be between 1-2%. This paper reports the survey on the prevalence of vitiligo in Bangalore (India). The prevalence was found to be Vitiligo is 0.71%. A total of 22037 people were contacted in the survey cutting across all segments of the society. A total of 160 people were ...
A comparative evaluation of the antidiabetic and hypoglycaemic potential of the extracts from dif... more A comparative evaluation of the antidiabetic and hypoglycaemic potential of the extracts from different plant parts of Musa paradisiaca (MP) was carried out in vitro. MP extracts were prepared sequentially with methanol, chloroform and petroleum ether. A comparison was made between the action of extracts from different parts. Different concentrations of each extract were made by using phosphate buffer and subjected to αamylase and α-glucosidase inhibitory assays using maltose and 2-Chloro-4-Nitrophenyl-α-Maltotrioside as substrates respectively. Using this method, the percentage of α-amylase inhibitory activities of each extract were calculated. The enzymes were extracted from the sheep intestines. The absorbencies ware read at 595 nm and 405nm respectively using spectrophotometer. Methanol extracts were found to show higher inhibition. It was found that fruit and stem extract showed high rate of inhibition. At 100 μg/ml concentration of the stem extract a high of 83% inhibition of ...
The Open Drug Discovery Journal, 2010
The study was carried out to ascertain anti asthmatic, analgesic and anti convulsant activities o... more The study was carried out to ascertain anti asthmatic, analgesic and anti convulsant activities of the medicinal plant Bryonia Laciniosa . The anti asthmatic activity was estimated by mesenteric mast cell count by Atopic allergy method. Eddy's hot plate and Analgesiometer tests were used to assess the analgesic activity of Bryonia Laciniosa . Anticonvulsant activity was evaluated by Maximum electroshock- induced seizure test. The results indicated that 70% alcoholic extract of Bryonia laciniosa increased the antiasmatic activity, analgestic activity and also anticonvulsant activity. Keywords: Bryonia Laciniosa , Atopic allergy method, Eddy's hot plate analgesio meter, Electric shock method.
Objective: Insulin is used to manage diabetes mellitus by subcutaneous injections regulary, that ... more Objective: Insulin is used to manage diabetes mellitus by subcutaneous injections regulary, that has become a part of patients life and is distressing for patients. Hence, we anticipate to get rid of the usage of subcutaneous injections completely from the medicine world and would make the diabetic people to say as “farewell to painful injections.” Methods: Virtual screening method (for selection of carriers), Toxtree tool (for toxicity evaluation of carriers), and discovery studio tool (for pharmacophore designing, absorption, distribution, metabolism, excretion, and toxicity [ADMET] analysis, designing oral insulin conjugates (OICs), and interaction studies between insulin receptor and OICs) were used for proposed study. Results: We have screened 14 competent drug delivering molecules (DDMs) from seven chemical compound databases. The ADMET and pharmacophoric properties of DDMs were analyzed by drug-informatics’ tools. Consequently, the DDMs were mono, di, and poly conjugated by c...
Journal of Molecular Structure, 2013
h i g h l i g h t s Molecular and crystal structure of a simple diacid. Investigation of structur... more h i g h l i g h t s Molecular and crystal structure of a simple diacid. Investigation of structure by single crystal X-ray diffraction. Malonic acid forms continuous hydrogen bonded chains through carboxylic acid.
International Journal of Environmental Analytical Chemistry, 2006
Page 1. Intern. J. Environ. Anal. Chem. Vol. 86, No. 10, 20 August 2006, 757765 Electrochemical ... more Page 1. Intern. J. Environ. Anal. Chem. Vol. 86, No. 10, 20 August 2006, 757765 Electrochemical reduction behaviour of the synthetic pyrethroid insecticide cyfluthrin and its determination in formulations and environmental samples ...
Helvetica Chimica Acta, 2006
Both aliphatic and aromatic amino sulfonamides such as mafenide (1a) were synthesized in good yie... more Both aliphatic and aromatic amino sulfonamides such as mafenide (1a) were synthesized in good yields (80-86%) by direct electrochemical hydrogenation of the corresponding nitriles in an undivided cell containing a Ni cathode, a Pt anode, and Raney Ni as catalyst (Table 1). The reaction can be performed without external supply of pressurized gas by in situ generation of H 2. Slightly elevated temperatures (458) and low current densities (10 mA/cm 2) are favorable conditions for this type of electrochemical nitrile hydrogenation. Our synthetic protocol does not require high-pressure equipment or chemical hazards, is environmentally very friendly, and more economical than traditional methods. The concentration of adsorbed HC radicals on the catalyst surface can be easily controlled by adjusting the electric potential, which may lead to improved product selectivity and, at the same time, reduces the risk of explosion and fire. Introduction.-Amino sulfonamides are important synthetic organic compounds that often exhibit antibacterial and antifungal activities [1] [2]. Therefore, some of these compounds are called 'sulfa medicines', one example being mafenide (1a), which is being used in the treatment of acute burns [3]. The synthesis of amino sulfon-A C H T U N G T R E N N U N G amides from the corresponding nitriles by (catalytic) reduction is very important. In this process, primary amines are obtained, which form a large group of compounds widely used in pharmaceuticals and agrochemicals [4]. Nitrile reduction is also very important both in synthetic [5] and industrial [6] chemistry. Miller et al. have synthesized several amino sulfonamides by catalytic reduction of cyano compounds, nitro sulfonamides, or N-acyl derivatives [1].
Crystal Growth & Design, 2012
Transition metal complexes of the ligand 2,2′-bipyridine-4,4′-diamine (bpy4da) form three-dimensi... more Transition metal complexes of the ligand 2,2′-bipyridine-4,4′-diamine (bpy4da) form three-dimensional (3D) hydrogen bonding networks with the [M(bpy4da) 3 ] 2+ species, a hydrogen donor metallo-tecton with carboxylate counteranions as hydrogen bond acceptors within the complexes [[Ni(bpy4da) 3 ]•(Hbpc)(bpc) 0.5 (dmf) n , [Ni-(bpy4da) 3 ].(bpc)(dmf) n , and [Ni(bpy4da) 3 ]•(Htma)•4(dmf) where H 2 bpc = biphenyl-4,4′-dicarboxylic acid, H 3 tma = trimesic acid, and dmf = dimethylformamide. Terephthalate, on the other hand, bridges between Cu(II) centers in complexes [Cu 2 (bpy4da) 4 (tpa)]•2(NO 3)•5(dmf) and [Cu 2 (bpy4da) 4 (tpa)]•2(NO 3)•4.5(dmf)•(H 2 O) (where H 2 tpa = terephthalic acid) whose structures both feature different 3D hydrogen bonded networks. The crystal structures of hydrated [Cd(bpy4da) 3 ]•2Cl and [Co(bpy4da) 2 (NO 3)] 2 •2(NO 3)•4.5(dmf) are also reported.
Page 1. International Journal of Pharmaceuticals Analysis, ISSN: 0975-3079, Volume 2, Issue 2, 20... more Page 1. International Journal of Pharmaceuticals Analysis, ISSN: 0975-3079, Volume 2, Issue 2, 2010, pp-05-16 Copyright © 2010, Bioinfo Publications, International Journal of Pharmaceuticals Analysis, ISSN: 0975-3079, Volume 2, Issue 2, 2010 ...
International Journal of Agriculture Sciences, 2009
Forty two strains of Trichoderma sp. were isolated from cultivated lands around Bangalore and ana... more Forty two strains of Trichoderma sp. were isolated from cultivated lands around Bangalore and analyzed for their antagonistic potential against Sclerotium rolfsii and Fusarium ciceri. The potential of biocontrol agents ultimately lies in their capacity to control pathogens in vivo. Bioefficacy studies were hence conducted using chickpea (Cicer argentums c.v. Annigeri) as an experimental plant by the roll paper towel method. Overall the isolates T40, T35, T30 and T25 showed better antagonistic potential in addition to enhancing plant growth. The production of chitinases to break down the mycelial cell walls of fungal plant pathogens has been implicated as a major cause of biocontrol activity (Inbar and Chet, 1995). In order to study the mechanism of biocontrol, ten better performing strains were plated on media, amended with colloidal chitin and Sclerotium rolfsii cell wall extract. All the isolates showed chitinolytic activity on day three as well as day five. Production of endochitinase and exochitinase were assayed in liquid media using colloidal chitin amended broth. Strains T35 and T6 displayed maximum endochitinase and exochitinase activity. Although all strains exhibited cellulase activity, the quantum of enzyme produced was higher in T35 and T6. The results also indicate a positive correlation between enzyme production and bioefficacy.
International Journal of Environment, Agriculture and Biotechnology, 2022
Palynology is the study of pollen grain and spores. The term forensic when inserted into the pict... more Palynology is the study of pollen grain and spores. The term forensic when inserted into the picture marks the usage of pollen into a crime-solving and suspect finding tool. Pollen grain has an outer layer made up of sporopollenin which gives high durability and resistance due to which pollen can survive at adverse and extreme conditions. The samples collected from the crime scene are analysed, studied and investigated along with the samples obtained from the suspects. A relation is derived which acts as evidence during the judicial custody. Pollen analysis is highly useful if a crime that has happened long back, and now needs to be opened up. Advancement of this technique in India is still awaited.