Eman Elkattan | Cairo University (original) (raw)

Papers by Eman Elkattan

The Egyptian Rheumatologist, Oct 1, 2011

Aim of the work: To evaluate the uterine-umbilical artery Doppler velocimetry and determine its r... more Aim of the work: To evaluate the uterine-umbilical artery Doppler velocimetry and determine its relation to pregnancy outcome and disease manifestations in SLE patients. Patients and methods: Blood flow velocity waveforms of the umbilical and uterine arteries were studied by color Doppler ultrasound in 36 pregnant SLE patients referred from the Rheumatology Department for follow up and delivery in the Obstetrics Department. Resistance index (RI) and pulsality index (PI) were measured at the 1st week and then every 4 weeks from the 20th and 30th weeks till delivery. Results: The mean age was 27.33 ± 4.03 years and disease duration of 5.72 ± 2.57 years. The nulliparity rate and history of previous abortions were higher in those with poor fetal outcome (50% and 62.5%, respectively). Lupus anticoagulants and anticardiolipin were obviously higher in those with a poor outcome (25% and 37.5%, respectively) with a higher association with APS in spite of anticoagulation. The SLEDAI was higher in those with a poor fetal outcome and the difference reached significance at the 24th week gestation (12.13). Eight (22.22%) of the patients had abnormal fetal outcome: 5 IUGR (13.89%), 1 IUFD (2.78%) and 2 (5.55%) with missed abortion. Uterine and umbilical artery Doppler abnormalities were higher in those with poor obstetric outcomes and were earlier revealed by the uterine.

Middle East Fertility Society Journal, Apr 1, 2010

ObjectiveTo measure the accuracy of the ultrasonographic features in predicting adenomyosis and t... more ObjectiveTo measure the accuracy of the ultrasonographic features in predicting adenomyosis and to determine if there is a role for uterine artery Doppler in adenomyosis prediction.

Middle East Fertility Society Journal, Jun 1, 2013

Middle East Fertility Society Journal, Mar 1, 2016

To determine if the three-dimensional power Doppler and uterine arteries Doppler were able to dif... more To determine if the three-dimensional power Doppler and uterine arteries Doppler were able to differentiate between fibroids and adenomyomas. Methods: 123 patients who were scheduled for hysterectomy were enrolled in the study. They were evaluated by ultrasound before hysterectomy. We included only cases with either fibroids or adenomymas. For each benign myometrial mass, mass volume, 3D power Doppler vascularization index (VI), flow index (FI) and vascularization flow index (VFI) and uterine artery Doppler indices were measured. The results were compared with the histopathological examination. Results: No significant difference was detected between the volume of the fibroids or the adenomyomas (P = 0.896). There was significant difference in the vascular location of the power Doppler flow between fibroids and adenomyomas being more scattered in adenomyoma and more peripheral in fibroids (P < 0.00). In fibroids, higher 3D power Doppler vascular flow (VI = 2.42 ± 2.0, FI = 39.931 ± 5.8 and VFI = 1.29 ± 1.54) than adenomyomas (VI = 1.19 ± 1.04, FI = 28.33 ± 6.88, VFI = 0.89 ± 0.49). That was statistically significant (P = 0.005, 0.00, 0.004) respectively. The uterine artery Doppler indices (RI, PI) showed no significant difference between fibroids and adenomyoma (P = 0.349, 0.067). Conclusion: 3D power Doppler can differentiate between fibroids and adenomyomas. The uterine arteries Doppler Can't differentiate between fibroids and adenomyomas.

Evidence Based Women Health Journal (Online), May 1, 2015

We assessed whether there is an effect of rectal misoprostol (a prostaglandin E 1 analogue) on in... more We assessed whether there is an effect of rectal misoprostol (a prostaglandin E 1 analogue) on intestinal motility in women who had cesarean sections. Patients and methods A total of 120 women who had an elective cesarean section under spinal anesthetic were recruited for a randomized controlled trial. They were randomized into three groups: group A, who did not take misoprostol; group B, who took 200 mg misoprostol; and group C, who took 400 mg misoprostol. We compared the three groups with respect to time to pass flatus, time till the bowel sounds were heard, time to start regular diet, and side effects of misoprostol. Results No statistical difference was seen as regard age, parity, BMI, number of previous cesarean sections, and duration of surgery. There was no statistical difference with regard to the presence of bowel sounds, but time to pass flatus and time to start regular diet were significantly shorter in the group who did not take misoprostol (Po0.001). A statistically significant difference between the three groups was found with regard to fever (P = 0.003), nausea (P = 0.001), vomiting (P = 0.002), abdominal distension (Po0.001), and need for analgesia (Po0.001), which were significantly more in the group who took 400 mg misoprostol in comparison with other groups. Hospital stay was significantly shorter in women who did not take misoprostol (P = 0.001), but no statistically significant difference found between groups with regard to postpartum hemorrhage. Conclusion Misoprostol does not seem to be beneficial in improving the intestinal motility in women who had cesarean section.

Journal of Diagnostic Medical Sonography, 1992

Journal of obstetrics and gynaecology Canada, Jul 1, 2010

To study the relationship between obesity and serum and ultrasound markers of ovarian reserve in ... more To study the relationship between obesity and serum and ultrasound markers of ovarian reserve in premenopausal women. We performed a cross-sectional comparative study of two age-matched groups of premenopausal participants (early transition phase): 50 participants (&amp;amp;amp;amp;amp;amp;amp;quot;non-obese&amp;amp;amp;amp;amp;amp;amp;quot;) had a BMI &amp;amp;amp;amp;amp;amp;amp;lt; 30 kg/m2, and the other 50 participants (&amp;amp;amp;amp;amp;amp;amp;quot;obese&amp;amp;amp;amp;amp;amp;amp;quot;) had a BMI of 30 to 35 kg/m2. The obese women had a mean age of 46.2 years and the non-obese women had a mean age of 46.1 years. Blood samples were collected from all participants, anthropometric measurements were calculated, and transvaginal ultrasonography was performed to measure the antral follicle count (AFC) and ovarian volume during the early follicular phase. The blood samples were assayed for antimüllerian hormone (AMH), follicle-stimulating hormone (FSH), fasting blood glucose (FBG) and two-hour postprandial blood glucose (2h PP). There was no significant difference between the two groups in mean age, levels of serum AMH, serum FSH, FBG, 2 hr PP, or AFC. Ovarian volume was significantly lower in obese women (3.7 +/- 0.8 mL) than in non-obese women (6.6 +/- 0.4 mL) (P = 0.03). There was no significant correlation between BMI and serum AMH, serum FSH, FBS, or 2 hr PP. Obesity has no association with levels of serum FSH, AMH, blood glucose, or AFC indicating that obesity is unlikely to affect ovarian reserve in the perimenopausal age group.

International Journal of Fertility & Sterility, 2016

Background The aim of this study was to evaluate the relationship between ultrasonographic findin... more Background The aim of this study was to evaluate the relationship between ultrasonographic findings and serum progesterone and cancer antigen-125 (CA-125) levels in threatened miscarriage and to predict pregnancy outcome. Materials and Methods In a prospective comparative case-control study, serum CA-125 and progesterone levels were measured for 100 pregnant women with threatened miscarriage who attended the outpatient clinic or the causality department of Obstetrics and Gynecology at Kasr El-Aini Hospital, Giza, Egypt, during the period from March 2013 to October 2013. Ultrasound was performed for fetal viability, crown-rump length (CRL), gestational sac diameter (GSD) and fetal heart rate (FHR). The patients were followed up and divided into two groups based on the outcome: 20 women who miscarried (group 1), and 80 women who continued pregnancy (group 2). The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and overall accuracy were teste...

The Egyptian Journal of Radiology and Nuclear Medicine, 2016

Infectious Agents and Cancer, 2016

Background: The association of human papillomavirus (HPV) with cervical cancer is well establishe... more Background: The association of human papillomavirus (HPV) with cervical cancer is well established. Aim: To investigate HPV genotype distribution and co-infection occurrence in cervical specimens from a group of Egyptian women. Methods: A group of 152 women with and without cervical lesions were studied. All women had cervical cytology and HPV testing. They were classified according to cytology into those with normal cytology, with squamous intraepithelial lesions (SIL) and invasive squamous cell carcinoma (SCC). Cervical samples were analyzed to identify the presence of HPV by PCR, and all positive HPV-DNA samples underwent viral genotype analysis by means of LINEAR ARRAY HPV Genotyping assay. Results: A total of 26 HPV types with a prevalence of 40.8 % were detected. This prevalence was distributed as follows: 17.7 % among cytologically normal females, 56.5, 3.2, and 22.6 % among those with LSIL, HSIL and invasive SCC respectively. Low-risk HPV types were detected in 81.8 % of the cytologically-normal women, in 5.7 % of those in LSIL women, and in 14.3 % of infections with invasive SCC, while no low-risk types were detected in HSIL. High-risk HPV types were detected in 18.2 % of infections in the cytologically normal women, 14.3 % of infections in LSIL, and in 21.4 % of invasive lesions. The probable and possible carcinogenic HPV were not detected as single infections. Mixed infection was present in 80 % of women with LSIL, in 100 % of those with HSIL, and in 64.3 % of those with invasive SCC. This difference was statistically significant. HPV 16, 18 and 31 were the most prevalent HR HPV types, constituting 41.9, 29.03 and 12.9 % respectively, and HPV 6, 62 and CP6108 were the most prevalent LR HPV types constituting 11.3, 9.7 and 9.7 % respectively. Conclusion: These data expand the knowledge concerning HPV prevalence and type distribution in Egypt which may help to create a national HPV prevention program. HPV testing using the LINEAR ARRAY HPV Genotyping assay is a useful tool when combined with cytology in the diagnosis of mixed and non-conventional HPV viral types.

Ultrasound in Obstetrics and Gynecology, 2009

Oral poster abstracts holoprosencephaly was ruled out in a case of severe hydrocephaly with agene... more Oral poster abstracts holoprosencephaly was ruled out in a case of severe hydrocephaly with agenesis of corpus callosum, a definitive diagnosis of bilateral open lip schizencephaly was made and a case with suspected intraventricular hemorrhage was ruled out, although it missed an arachnoid cyst shown by US. Conclusion: Our preliminary results suggest that neurosonography performed by dedicated sonologists using both 2D/3D transabdominal and transvaginal sonography provides equal results to MRI in the diagnosis of most fetal brain anomalies. MRI supplied important clinically useful information in selected cases of brain anomalies. Therefore, both diagnostic tools can and probably should be used to complement each other. OP05.02 3D multislice analysis of ultrasound volumes for the prenatal diagnosis of central nervous system fetal malformations

Evidence Based Womenʼs Health Journal, 2015

Middle East Fertility Society Journal

Middle East Fertility Society Journal, 2013

Objective: To compare endometrial receptivity of letrozole and clomiphene citrate. Study design: ... more Objective: To compare endometrial receptivity of letrozole and clomiphene citrate. Study design: A prospective comparative study. Subjects: 120 women with unexplained infertility undergoing superovulation. Intervention: Sixty patients underwent ovulation induction using 5 mg letrozole compared with another 60 patients using 100 mg clomiphene citrate.

The Egyptian Rheumatologist, 2011

Journal of the Turkish German Gynecological Association, 2009

To detect the serum levels of folate and B12 in both preclamptic and normotensive pregnant women ... more To detect the serum levels of folate and B12 in both preclamptic and normotensive pregnant women and to determine whether there is any relation between these levels with the uterine and umbilical artery Doppler indices as well as the pregnancy outcome. This case controlled study comprised 79 pregnant patients with preeclampsia and 113 healthy, normotensive pregnant women with singleton pregnancies at gestational ages ranging from 34-40 weeks. Patients were not obese (BMI<30) and did not suffer from chronic hypertension, chronic renal or liver disease nor diabetes mellitus. Serum folate and B12 were detected in all cases. They were also subjected to a Doppler study of both the uterine and umbilical arteries. Serum folate and B12 blood levels as well as the Doppler study indices (RI and PI) were compared in both groups. The serum folate level was significantly lower in preeclamptic patients than normal pregnant women (p<0.001). It was significantly correlated to uterine artery D...

Middle East Fertility Society Journal, 2015