Haithem Farghali | Cairo University (original) (raw)

Papers by Haithem Farghali

Veterinary Medical Journal (Giza)

The orthopedic hind limb affections in dogs constituted 31.99 % of the admitted cases to the Surg... more The orthopedic hind limb affections in dogs constituted 31.99 % of the admitted cases to the Surgery clinic, Faculty of Vet. Med. Cairo univ., while the corresponding percentage in cats was 11.70 % during the period from October 2010 to April 2013. Pelvic limb fractures accounted for 50.60 % of the orthopedic dog patients, whereas, pelvic limb fracture in cats represented 69.39%. Femoral fracture in dogs constituted 56.80% of pelvic limb fractures, whereas, femoral fracture in cats comprised 59.80 %. The highest proportion in femoral fracture in dogs was in midshaft fracture (46.10 %), while in cats was the supracondylar fracture (57.41 %).

Oral cavity affections become more widely distributed among pet animals including both dogs and c... more Oral cavity affections become more widely distributed among pet animals including both dogs and cats all over the world. In our study, the incidence of orodental affections in examined dogs of different sexes and ages (693) were (78.8%). Soft tissue affections were recorded in (28) cases represented (5.5%) from the total affected cases (504) and represent (6.8%) from the recorded acquired affections (411). The recorded cases related to the soft tissue were oro-nasal fistula (10.7%), gingivostomatitis(14.2%), wound(17.8%), ulcers(14.2%) and foreign bodies(10.7%) of the oral cavity, some oral tumors (17.8%), epulis (7.1%), and salivary mucoceles (7.1%). {Citation: Inas N. El Husseiny, Haithem A. Farghali, Aya N. Mohamed. Survey study on soft tissue affections of the oral cavity in dogs. American Journal of Research Communication, 2016, 4(1): 98112} www.usa-journals.com, ISSN:2325-4076.

Feline intestinal lymphosarcomas are mostly caused by Feline Leukemia Virus (FeLV). Unfortunately... more Feline intestinal lymphosarcomas are mostly caused by Feline Leukemia Virus (FeLV). Unfortunately, there is no available vaccine for FeLV in Egypt. The diagnosis of feline intestinal lymphosarcomas depends upon abdominal palpation, x-rays examination, ultrasonography, direct ELISA and histopathology of masses excised during laparotomy. The recorded clinical signs in intestinal lymphosarcoma affected cats were variable including vomiting, fever, anorexia, ascites, anemia, dyspnea, constipation and emaciation. The affected lymph nodes were mesenteric, mediastinal and retropharyngeal. The prevalence of intestinal lymphosarcomas in the examined cats was 4.03 % (11 out of 273 cats). The prevalence was higher in queens than toms (2.93 % and 0.73 % respectively). The Siamese cats had higher prevalence than the Sherazy ones (2.56 % and 1.47 % respectively). X-ray films and ultrasonographic images performed on the eleven cats suffered from intestinal lym-phosarcomas revealed ascities and abd...

Aims: Spinal cord injuries (SCIs) can cause severe disability or death. The principal treatments ... more Aims: Spinal cord injuries (SCIs) can cause severe disability or death. The principal treatments for traumatic SCI include surgical stabilization and decompression. Using muscle as a scaffold is a new approach. The aim of this work is to evaluate the clinical efficacy of muscle graft as a scaffold for the growing axons organizing their growth, preventing gliosis in the damaged area and enhancing neural recovery in canine model of traumatic spinal cord injury. Methods: 14 dogs were divided into group I (Control group) 4 control dogs subjected to Sham operation , group II (Trauma control group) 5 dogs subjected to dorsal laminectomy with excision of 1 cm segment of the spinal cord and group III (Muscle graft group) 5 dogs subjected to dorsal laminectomy then muscle graft was taken from the longissimus thoraces and inserted into the spinal cord gap. The animals of all groups were euthanatized after 8 weeks. Olby and modified Tarlov scores were used to clinically evaluate the therapeuti...

Veterinary Medical Journal (Giza), 2021

The Journal of American Science, 2011

Medicinal and surgical diseases are most common health problems in police guard and explosive dog... more Medicinal and surgical diseases are most common health problems in police guard and explosive dogs used for protection of organizations of high economic importance and tourism in Egypt. The present study was aimed to calculate the percentage of most common diseases and to evaluate the degree of success for routine management of these problems. The present survey was carried out on 151 dogs resulted in 1229 cases in different body systems from 11/ 2007 to 2/ 2010. These problems arranged according to percentage in descending manner as follow: pruritus (24.8%) which recorded the highest percentage followed by Ticks (16.4%), surgical wounds (9.8%), diarrhea (9.1%), otic pruritus or ear infection (8.5%), vomiting (5.2%), scrotal affections (4.2%), general weakness (3.4%), bone affections (2.6%), respiratory signs (2.4%), ear trauma or ear hematoma (2.12%), fever (2.1%), tail arrada (1.7%), alopecia without itching (1.51%), deaths and euthanesia (1.5%), muscle affections (1.4%), hemorrha...

3 Abstract: The aim of the present work was to study the incidence of the canine hip dysplasia (C... more 3 Abstract: The aim of the present work was to study the incidence of the canine hip dysplasia (CHD)among different breeds of dogs in Egypt to see how we are far away from the CHD problem. A retrospective study based on the database of the 2013 archive at the Referral Veterinary Hospital in Egypt was carried out to determine the incidence of canine hip dysplasia in Egypt. A total of 8956 dogs were admitted to the hospital during this year. Dogs with suspected CHD were subjected to complete case history and thorough clinical examination. Final diagnosis of CHD based upon hip radiography and color Doppler ultrasonography.Out of 8956 dogs, 2058 animals had CHD representing 22.9% of the total examined dogs. Gait abnormalities, difficulty in rising, climbing stairs or in jumping over obstacles were the reported clinical signs of CHD. The incidence of CHD among different examined dogs, breeds was 36.14%, 32.68%, 30.78%, 27.28%, 27.23%, 23.99%, 22.64%, 17.1%, 13.33%, 12.5%, 11.62%, 7.31%, ...

21 2 Abstract: The present investigation has been dealt with Spirocerca (S.) lupi infested mongre... more 21 2 Abstract: The present investigation has been dealt with Spirocerca (S.) lupi infested mongrel dogs. This parasitic disease is highly infective to human beings and carnivores. The diagnosis march has been comprised the lateral contrast thoracic radiographs, fecal examination, blood profile, endoscopic examination and histopathological sections of deep seated pinch biopsies. These infested dogs have been put under an adopted treatment with Ivermectin injection combined with oral prednisolone. The obtained results reveal absence of the pessimistic recognitions particularly after 3 weeks from the onset of treatment. Endoscopically the presented esophageal nodules are marked out in the distal third of infested dogs' esophagus as masses assigned into the esophageal lumen and fundus of stomach. The endoscopic outlook of Spirocerca lupi lesions has been considered an integral procedure of the diagnostic march and for evaluation of treatment follow up. The diagnostic procedures and ...

Veterinary Medicine – Open Journal, 2017

World's Veterinary Journal, 2020

Appendicular bone fractures in small animal practice constitute a major challenge facing veterina... more Appendicular bone fractures in small animal practice constitute a major challenge facing veterinary orthopedic surgeons concerning affected limb and bone as well as the extent of tissue damage, site, and shape of the fracture line. Therefore, this retrospective study was designed to provide descriptive data at referral veterinary teaching hospital, faculty of veterinary medicine, Cairo University, and some private pet clinics in Cairo district, Egypt to identify and determine the prevalence of appendicular fractures arising from trauma in dogs and cats treated from January 2017 to January 2020, and emphasizing the information that characterized the population (breed, age, gender, and animal size). The investigated fractures were classified according to the specific limb (forelimbs / hind limbs), specific bone fractures (Humerus, radius and ulna, femur, tibia and fibula, and the other bones), extent of tissue damage (open or closed and incomplete or complete), site (proximal, diaphys...

Camel-derived haemoglobin O2 carriers (CHBOC) are being developed as a blood substitutes for allo... more Camel-derived haemoglobin O2 carriers (CHBOC) are being developed as a blood substitutes for allogeneic RBCs or to improve tissue oxygenation. The tolerability of the developed product was evaluated in 10 moderately exsanguinated (40%) experimental mongrel dogs that were randomized to receive either 40 g/l CHBOC dissolved in lactated Ringer's solution at a rate of 5 ml/kg (Test group-14 trials) or 6 g/l HES 200 solution-6% hydroxyethyl starch (Fresenius Kabi-Germany) dissolved in saline at a rate of-5ml/kg-(Control group-6 trials). Overall, the clinical, haematological and biochemical responses were normal. The CHBOC was well tolerated and a promising product. However additional studies are needed to confirm the safety of the new CHBOC product in the realm of acellular blood transfusion.

Cell transplantation, Jan 15, 2014

Spinal cord injury (SCI) results in demyelination of surviving axons, loss of oligodendrocytes, a... more Spinal cord injury (SCI) results in demyelination of surviving axons, loss of oligodendrocytes, and impairment of motor and sensory functions. We have developed a clinical strategy of cell therapy for SCI through the use of autologous bone marrow cells for transplantation to augment remyelination and enhance neurological repair. In a preclinical large mammalian model of SCI, experimental dogs were subjected to a clipping contusion of the spinal cord. Two weeks after the injury, GFP-labeled autologous minimally manipulated adherent bone marrow cells (ABMCs) were transplanted intrathecally to investigate the safety and efficacy of autologous ABMC therapy. The effects of ABMC transplantation in dogs with SCI were determined using functional neurological scoring, and the integration of ABMCs into the injured cords were determined using histopathological and immunohistochemical investigations, and electron microscopic analyses of sections from control and transplanted spinal cords. Our d...

Veterinary Medical Journal (Giza)

The orthopedic hind limb affections in dogs constituted 31.99 % of the admitted cases to the Surg... more The orthopedic hind limb affections in dogs constituted 31.99 % of the admitted cases to the Surgery clinic, Faculty of Vet. Med. Cairo univ., while the corresponding percentage in cats was 11.70 % during the period from October 2010 to April 2013. Pelvic limb fractures accounted for 50.60 % of the orthopedic dog patients, whereas, pelvic limb fracture in cats represented 69.39%. Femoral fracture in dogs constituted 56.80% of pelvic limb fractures, whereas, femoral fracture in cats comprised 59.80 %. The highest proportion in femoral fracture in dogs was in midshaft fracture (46.10 %), while in cats was the supracondylar fracture (57.41 %).

Oral cavity affections become more widely distributed among pet animals including both dogs and c... more Oral cavity affections become more widely distributed among pet animals including both dogs and cats all over the world. In our study, the incidence of orodental affections in examined dogs of different sexes and ages (693) were (78.8%). Soft tissue affections were recorded in (28) cases represented (5.5%) from the total affected cases (504) and represent (6.8%) from the recorded acquired affections (411). The recorded cases related to the soft tissue were oro-nasal fistula (10.7%), gingivostomatitis(14.2%), wound(17.8%), ulcers(14.2%) and foreign bodies(10.7%) of the oral cavity, some oral tumors (17.8%), epulis (7.1%), and salivary mucoceles (7.1%). {Citation: Inas N. El Husseiny, Haithem A. Farghali, Aya N. Mohamed. Survey study on soft tissue affections of the oral cavity in dogs. American Journal of Research Communication, 2016, 4(1): 98112} www.usa-journals.com, ISSN:2325-4076.

Feline intestinal lymphosarcomas are mostly caused by Feline Leukemia Virus (FeLV). Unfortunately... more Feline intestinal lymphosarcomas are mostly caused by Feline Leukemia Virus (FeLV). Unfortunately, there is no available vaccine for FeLV in Egypt. The diagnosis of feline intestinal lymphosarcomas depends upon abdominal palpation, x-rays examination, ultrasonography, direct ELISA and histopathology of masses excised during laparotomy. The recorded clinical signs in intestinal lymphosarcoma affected cats were variable including vomiting, fever, anorexia, ascites, anemia, dyspnea, constipation and emaciation. The affected lymph nodes were mesenteric, mediastinal and retropharyngeal. The prevalence of intestinal lymphosarcomas in the examined cats was 4.03 % (11 out of 273 cats). The prevalence was higher in queens than toms (2.93 % and 0.73 % respectively). The Siamese cats had higher prevalence than the Sherazy ones (2.56 % and 1.47 % respectively). X-ray films and ultrasonographic images performed on the eleven cats suffered from intestinal lym-phosarcomas revealed ascities and abd...

Aims: Spinal cord injuries (SCIs) can cause severe disability or death. The principal treatments ... more Aims: Spinal cord injuries (SCIs) can cause severe disability or death. The principal treatments for traumatic SCI include surgical stabilization and decompression. Using muscle as a scaffold is a new approach. The aim of this work is to evaluate the clinical efficacy of muscle graft as a scaffold for the growing axons organizing their growth, preventing gliosis in the damaged area and enhancing neural recovery in canine model of traumatic spinal cord injury. Methods: 14 dogs were divided into group I (Control group) 4 control dogs subjected to Sham operation , group II (Trauma control group) 5 dogs subjected to dorsal laminectomy with excision of 1 cm segment of the spinal cord and group III (Muscle graft group) 5 dogs subjected to dorsal laminectomy then muscle graft was taken from the longissimus thoraces and inserted into the spinal cord gap. The animals of all groups were euthanatized after 8 weeks. Olby and modified Tarlov scores were used to clinically evaluate the therapeuti...

Veterinary Medical Journal (Giza), 2021

The Journal of American Science, 2011

Medicinal and surgical diseases are most common health problems in police guard and explosive dog... more Medicinal and surgical diseases are most common health problems in police guard and explosive dogs used for protection of organizations of high economic importance and tourism in Egypt. The present study was aimed to calculate the percentage of most common diseases and to evaluate the degree of success for routine management of these problems. The present survey was carried out on 151 dogs resulted in 1229 cases in different body systems from 11/ 2007 to 2/ 2010. These problems arranged according to percentage in descending manner as follow: pruritus (24.8%) which recorded the highest percentage followed by Ticks (16.4%), surgical wounds (9.8%), diarrhea (9.1%), otic pruritus or ear infection (8.5%), vomiting (5.2%), scrotal affections (4.2%), general weakness (3.4%), bone affections (2.6%), respiratory signs (2.4%), ear trauma or ear hematoma (2.12%), fever (2.1%), tail arrada (1.7%), alopecia without itching (1.51%), deaths and euthanesia (1.5%), muscle affections (1.4%), hemorrha...

3 Abstract: The aim of the present work was to study the incidence of the canine hip dysplasia (C... more 3 Abstract: The aim of the present work was to study the incidence of the canine hip dysplasia (CHD)among different breeds of dogs in Egypt to see how we are far away from the CHD problem. A retrospective study based on the database of the 2013 archive at the Referral Veterinary Hospital in Egypt was carried out to determine the incidence of canine hip dysplasia in Egypt. A total of 8956 dogs were admitted to the hospital during this year. Dogs with suspected CHD were subjected to complete case history and thorough clinical examination. Final diagnosis of CHD based upon hip radiography and color Doppler ultrasonography.Out of 8956 dogs, 2058 animals had CHD representing 22.9% of the total examined dogs. Gait abnormalities, difficulty in rising, climbing stairs or in jumping over obstacles were the reported clinical signs of CHD. The incidence of CHD among different examined dogs, breeds was 36.14%, 32.68%, 30.78%, 27.28%, 27.23%, 23.99%, 22.64%, 17.1%, 13.33%, 12.5%, 11.62%, 7.31%, ...

21 2 Abstract: The present investigation has been dealt with Spirocerca (S.) lupi infested mongre... more 21 2 Abstract: The present investigation has been dealt with Spirocerca (S.) lupi infested mongrel dogs. This parasitic disease is highly infective to human beings and carnivores. The diagnosis march has been comprised the lateral contrast thoracic radiographs, fecal examination, blood profile, endoscopic examination and histopathological sections of deep seated pinch biopsies. These infested dogs have been put under an adopted treatment with Ivermectin injection combined with oral prednisolone. The obtained results reveal absence of the pessimistic recognitions particularly after 3 weeks from the onset of treatment. Endoscopically the presented esophageal nodules are marked out in the distal third of infested dogs' esophagus as masses assigned into the esophageal lumen and fundus of stomach. The endoscopic outlook of Spirocerca lupi lesions has been considered an integral procedure of the diagnostic march and for evaluation of treatment follow up. The diagnostic procedures and ...

Veterinary Medicine – Open Journal, 2017

World's Veterinary Journal, 2020

Appendicular bone fractures in small animal practice constitute a major challenge facing veterina... more Appendicular bone fractures in small animal practice constitute a major challenge facing veterinary orthopedic surgeons concerning affected limb and bone as well as the extent of tissue damage, site, and shape of the fracture line. Therefore, this retrospective study was designed to provide descriptive data at referral veterinary teaching hospital, faculty of veterinary medicine, Cairo University, and some private pet clinics in Cairo district, Egypt to identify and determine the prevalence of appendicular fractures arising from trauma in dogs and cats treated from January 2017 to January 2020, and emphasizing the information that characterized the population (breed, age, gender, and animal size). The investigated fractures were classified according to the specific limb (forelimbs / hind limbs), specific bone fractures (Humerus, radius and ulna, femur, tibia and fibula, and the other bones), extent of tissue damage (open or closed and incomplete or complete), site (proximal, diaphys...

Camel-derived haemoglobin O2 carriers (CHBOC) are being developed as a blood substitutes for allo... more Camel-derived haemoglobin O2 carriers (CHBOC) are being developed as a blood substitutes for allogeneic RBCs or to improve tissue oxygenation. The tolerability of the developed product was evaluated in 10 moderately exsanguinated (40%) experimental mongrel dogs that were randomized to receive either 40 g/l CHBOC dissolved in lactated Ringer's solution at a rate of 5 ml/kg (Test group-14 trials) or 6 g/l HES 200 solution-6% hydroxyethyl starch (Fresenius Kabi-Germany) dissolved in saline at a rate of-5ml/kg-(Control group-6 trials). Overall, the clinical, haematological and biochemical responses were normal. The CHBOC was well tolerated and a promising product. However additional studies are needed to confirm the safety of the new CHBOC product in the realm of acellular blood transfusion.

Cell transplantation, Jan 15, 2014

Spinal cord injury (SCI) results in demyelination of surviving axons, loss of oligodendrocytes, a... more Spinal cord injury (SCI) results in demyelination of surviving axons, loss of oligodendrocytes, and impairment of motor and sensory functions. We have developed a clinical strategy of cell therapy for SCI through the use of autologous bone marrow cells for transplantation to augment remyelination and enhance neurological repair. In a preclinical large mammalian model of SCI, experimental dogs were subjected to a clipping contusion of the spinal cord. Two weeks after the injury, GFP-labeled autologous minimally manipulated adherent bone marrow cells (ABMCs) were transplanted intrathecally to investigate the safety and efficacy of autologous ABMC therapy. The effects of ABMC transplantation in dogs with SCI were determined using functional neurological scoring, and the integration of ABMCs into the injured cords were determined using histopathological and immunohistochemical investigations, and electron microscopic analyses of sections from control and transplanted spinal cords. Our d...