Wesam A H M E D Tawfik | Cairo University (original) (raw)
Papers by Wesam A H M E D Tawfik
of final weight, weight gain %, specific growth rate, and feed intake. Compared with the control ... more of final weight, weight gain %, specific growth rate, and feed intake. Compared with the control group, serum amylase, lipase, and proteases activities of Nile tilapia significantly (P < 0.05) increased alongside the increase in dietary levels of C-NPs in a dosedependent manner. The counts of red blood cells and white blood cells as well as hemoglobin and hematocrit levels of Nile tilapia fed with 30-60 mg C-NPs/ kg diet were statistically (P < 0.05) higher than fish in the control group with no significant differences Abstract The current study investigated the effects of dietary curcumin nanoparticles (C-NPs) on the performance, hemato-biochemical profile, digestive enzymes activities, antioxidant status, humoral immunity, and liver and intestinal histology of Nile tilapia (Oreochromis niloticus). Fish (4.3 ± 0.5 g) were fed with diets enriched with 0.0 (control), 15, 30, 45, and 60 mg C-NPs/kg diet up to apparent satiety thrice a day for 60 days. The growth-stimulating effects of dietary C-NPs were significantly observed in terms
The recent growing emergence of H5N1 Avian influenza virus (AIV) mutants calls for the urgent nee... more The recent growing emergence of H5N1 Avian influenza virus (AIV) mutants calls for the urgent need for new effective antiviral drugs against AIV. Quercetin, is a promising natural candidate for treatment and prevention of AIV infection but unfortunately, low solubility and poor bioavailability of quercetin hinders its use in the medical field. Nanotechnology offers an innovative solution for enhancing quercetin solubility and bioavailability and subsequently boosts its therapeutic effect. In the current study quercetin nanoparticles were prepared by nanoprecipitation technique, quercetin nanoparticles showed a particle size range from 182nm to 240nm at flow rate 10 ml/ min, solvent/antisolvent volume ratio 1:12, stirring speed 1300 rpm and drug concentration 5mg/ml. The determined safe dilution of quercetin nanoparticles 10µg/ml had a significant inhibitory effect on the avian influenza virus H5N1 strain (EPI573317) indicated by reduction of the virus titer and the CPE in MDCK cells. Quercetin nanoparticles could be used as a new promising inhibitor for H5N1 AIV and is expected to be on the top of candidates as antiviral against influenza virus in the near future.
Drafts by Wesam A H M E D Tawfik
--, 2019
This is the contact of a unit that presents the GC service for all who are interested
of final weight, weight gain %, specific growth rate, and feed intake. Compared with the control ... more of final weight, weight gain %, specific growth rate, and feed intake. Compared with the control group, serum amylase, lipase, and proteases activities of Nile tilapia significantly (P < 0.05) increased alongside the increase in dietary levels of C-NPs in a dosedependent manner. The counts of red blood cells and white blood cells as well as hemoglobin and hematocrit levels of Nile tilapia fed with 30-60 mg C-NPs/ kg diet were statistically (P < 0.05) higher than fish in the control group with no significant differences Abstract The current study investigated the effects of dietary curcumin nanoparticles (C-NPs) on the performance, hemato-biochemical profile, digestive enzymes activities, antioxidant status, humoral immunity, and liver and intestinal histology of Nile tilapia (Oreochromis niloticus). Fish (4.3 ± 0.5 g) were fed with diets enriched with 0.0 (control), 15, 30, 45, and 60 mg C-NPs/kg diet up to apparent satiety thrice a day for 60 days. The growth-stimulating effects of dietary C-NPs were significantly observed in terms
The recent growing emergence of H5N1 Avian influenza virus (AIV) mutants calls for the urgent nee... more The recent growing emergence of H5N1 Avian influenza virus (AIV) mutants calls for the urgent need for new effective antiviral drugs against AIV. Quercetin, is a promising natural candidate for treatment and prevention of AIV infection but unfortunately, low solubility and poor bioavailability of quercetin hinders its use in the medical field. Nanotechnology offers an innovative solution for enhancing quercetin solubility and bioavailability and subsequently boosts its therapeutic effect. In the current study quercetin nanoparticles were prepared by nanoprecipitation technique, quercetin nanoparticles showed a particle size range from 182nm to 240nm at flow rate 10 ml/ min, solvent/antisolvent volume ratio 1:12, stirring speed 1300 rpm and drug concentration 5mg/ml. The determined safe dilution of quercetin nanoparticles 10µg/ml had a significant inhibitory effect on the avian influenza virus H5N1 strain (EPI573317) indicated by reduction of the virus titer and the CPE in MDCK cells. Quercetin nanoparticles could be used as a new promising inhibitor for H5N1 AIV and is expected to be on the top of candidates as antiviral against influenza virus in the near future.
--, 2019
This is the contact of a unit that presents the GC service for all who are interested