Dr. Chandrakant G Sawant | Central Agricultural University (CAU), Imphal (original) (raw)

Papers by Dr. Chandrakant G Sawant

Journal of Entomological Research, 2017

Economic parameters of silkworm viz., Disease incidence (%), weight of 10 matured larvae (g), eff... more Economic parameters of silkworm viz., Disease incidence (%), weight of 10 matured larvae (g), effective rate of rearing (ERR) (%), single cocoon weight (g), single shell weight (g), cocoon-shell ratio (%), cocoon yield per 10,000 brushed larvae (Kg), silk filament length (m), silk filament weight (g) and denier of silkworm (Bombyx mori L.) fed on mulberry(Morus alba) leaves treated with various concentrations of nutritional ingredients, were determined. The economic parameters of silkworm (Bombyx mori L.) enhanced due to supplementation with 0.2 % ascorbic acid.(Vit. C). Leaves treated with NPK along with ascorbic acid (Vit. C) can be used to increase the silk yield in commercial silkworm rearing.

Journal of Entomological Research, 2016

Indian Journal of Entomology, 2017

Nutrition of mulberry has a vital role in sericulture as it improves the growth, development, hea... more Nutrition of mulberry has a vital role in sericulture as it improves the growth, development, health, feed consumption and conversion, thereby improving the commercial traits of mulberry silkworm Bombyx mori L., as it influences its growth and cocoon production. Hence, the effect of three biofertilizers viz., vermicompost, Phosphobacteria, Azotobacter and their mixture was studied on weight of larvae, disease incidence, coccon weight, single shell weight, coccon shell ratio, effective rate of rearing, cocoon yield, cocoon filament length and weight, and denier of silkworm. The results revealed that significantly high weight of ten matured larvae (35.26 g), single cocoon weight (1.72 g), single shell weight (0.34 g), cocoon shell ratio (19.76%), cocoon yield/10, 000 larvae brushed (17.00 kg), cocoon filament length (928 m), cocoon filament weight (0.275 g), denier (2.66), lower disease incidence (1.33%) and highest effective rate of rearing (98.66%) were obtained in larvae fed with leaves of variety V-1 applied with vermicompost, Azotobacter and Phosphobacteria in equal proportions.

Journal of Entomological Research, 2016

the lepidopterous pest viz., Helicoverpa armigera (hubner) passed through two generations while, ... more the lepidopterous pest viz., Helicoverpa armigera (hubner) passed through two generations while, Amsacta moorie (buttler), passed through one generation each during summer. the highest larval mortality of H. armigera during its two generations in a year was recorded due to unknown reason (13.15 per cent) followed by nuclear polyhydrosis virus (7.60 per cent) and an unidentified parasitoid (6.81 per cent). The egg sterility was observed to be 13.14 per cent and its pupal mortality was due to unknown reason (9.91 per cent). the highest larval mortality of A. moorie was recorded due to unknown reason (13.97 per cent) followed by egg sterility (13.33 per cent) and pupal mortality due to unknown reason (13.15 per cent).

Annals of Plant Protection Sciences, 2016

All insecticides was effective in reducing jassids and thrips population on groundnut and imidacl... more All insecticides was effective in reducing jassids and thrips population on groundnut and imidacloprid 0.003% and dimethoate 0.04% exhibited highest efficacy. Among the insecticidal treatments tested in field, imidacloprid showed significantly superior in controlling jassids and thrips population and thereby, reduction in leaf damage and increasing in yield. Highest incremental cost benefit ratio 1: 16.52 was observed in imidacloprid followed by dimethoate (1: 12.75) treatments.

European Heart Journal, 2015

A combination of variable expression, age-related penetrance, and unpredictable arrhythmic events... more A combination of variable expression, age-related penetrance, and unpredictable arrhythmic events complicates management of relatives of arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) patients. We aimed to (i) determine predictors of ARVD/C diagnosis and (ii) optimize arrhythmic risk stratification among first-degree relatives of ARVD/C patients. Methods and results Detailed phenotypic and outcome data of 274 first-degree relatives (46% male; 36.5 + 18.9 years) of 138 ARVD/C probands were obtained. Ninety-six (35%) relatives were diagnosed with ARVD/C according to 2010 Task Force Criteria (TFC). Siblings had a threefold increased risk of ARVD/C diagnosis compared with parents and children (odds ratio 3.11, P , 0.001). Multivariable logistic regression identified symptoms (P , 0.001), being a sibling (P , 0.001), the presence of a pathogenic mutation (P , 0.001), and female sex (P ¼ 0.010) as predictors of ARVD/C diagnosis. During 6.7 + 3.8 years of follow-up, 21 (8%) relatives experienced a sustained ventricular arrhythmia (cycle length 271 + 48 ms). While being a sibling was a predictor of ARVD/C diagnosis, neither relatedness to the proband (P ¼ 0.185) nor malignant family history (P ¼ 0.347) was significantly associated with arrhythmic events. Meeting TFC independent of family history criteria had higher prognostic value for arrhythmic events than conventional 2010 TFC, which include family history [area under the receiver operating characteristic curve 0.95 (95% CI 0.93-0.97) vs. 0.85 (95% CI 0.82-0.88), P , 0.001]. Conclusion One-third of first-degree relatives develop manifest ARVD/C. Siblings have highest risk of disease, even after correcting for age and sex. Fulfilment of TFC independent of family history is superior to conventional TFC for arrhythmic risk stratification of relatives.

Heart Rhythm, 2015

Endurance exercise is associated with adverse outcomes in patients with arrhythmogenic right vent... more Endurance exercise is associated with adverse outcomes in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C). Exercise recommendations for family members remain undetermined. The purposes of this study were to determine if (1) endurance exercise (Bethesda class C) and exercise intensity (metabolic equivalent hours per year [MET-Hr/year]) increase the likelihood of fulfilling 2010 Task Force Criteria and ventricular arrhythmias/implantable cardioverter-defibrillator shock (ventricular tachycardia/ventricular fibrillation [VT/VF]), and (2) exercise restriction to the American Heart Association (AHA) minimum goal for healthy adults is associated with favorable outcomes of at-risk family members. Twenty-eight family members of 10 probands inheriting a PKP2 mutation were interviewed about exercise from age 10. Exercise threshold to maintain overall health was based on the 2007 AHA guidelines of a minimum 390 to 650 MET-Hr/year. After adjustment for age, sex, and family membership, both participation in endurance athletics (odds ratio [OR] 7.4, P = .03) and higher-intensity exercise (OR = 4.2, P = .004) were associated with diagnosis (n = 13). Endurance athletes were also significantly more likely to develop VT/VF (n = 6, P = .02). Family members who restricted exercise at or below the upper bound of the AHA goal (≤650 MET-Hr/year) were significantly less likely to be diagnosed (OR = 0.07, P = .002) and had no VT/VF. At diagnosis and first VT/VF, family members had accumulated 2.8-fold (P = .002) and 3.5-fold (P = .03), respectively, greater MET-Hr exercise than the AHA-recommended minimum. Those who developed VT/VF had performed particularly high-intensity exercise in adolescence compared to unaffected family members (age 10-14: P = .04; age 14-19: P = .02). The results of this study suggest restricting unaffected desmosomal mutation carriers from endurance and high-intensity athletics but potentially not from AHA-recommended minimum levels of exercise for healthy adults.

Cardiac Electrophysiology Clinics, 2015

Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is rare cardiomyopathy associa... more Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is rare cardiomyopathy associated with life-threatening arrhythmias and increased risk of sudden cardiac death. In addition to mutations in desmosomal genes, environmental factors such as exercise have been implicated in the pathogenesis of the disease. Recent studies have shown that exercise may be associated with adverse outcomes in ARVD/C patients. Based on current evidence, ARVD/C patients are recommended to limit exercise irrespective of their mutation status. In addition, some studies have suggested the presence of an entirely acquired form of the disease caused by exercise that has been dubbed exercise-induced ARVD/C.

BMJ case reports, Jan 14, 2012

D34. PULMONARY HYPERTENSION: ENDPOINTS AND OUTCOMES, 2011

Page 1. / Thematic Poster Session / Wednesday, May 18/8:15 D34 PULMONARY HYPERTENSION: ENDPOINTS ... more Page 1. / Thematic Poster Session / Wednesday, May 18/8:15 D34 PULMONARY HYPERTENSION: ENDPOINTS AND OUTCOMES AM-4:30 PM / Area A, Hall B (Upper Level), Colorado Convention Center Pulmonary Hypertension ...

Case Reports, 2012

Benign cystic teratoma of lung is an extremely rare tumour, which was first described in literatu... more Benign cystic teratoma of lung is an extremely rare tumour, which was first described in literature by Mohr in 1839. Intrapulmonary teratoma is thought to be a derivative of the third endo-dermal pharyngeal pouch, which is an anlage of the thymus. The authors present a rare case of mature cystic teratoma in a young male involving the right upper lobe of the lung. Diagnosis is often missed and patients are treated for various infectious conditions. Treatment is complete resection for both benign and malignant teratomas and carries excellent prognosis. Benign cystic teratoma, if not excised may cause grave complications like life-threatening haemoptysis or malignant transformation with metastatic disease.

Journal of the American College of Cardiology, 2014

A study was conducted to observe the predatory potential of Cryptolaemus montrouzieri Mulsant) on... more A study was conducted to observe the predatory potential of Cryptolaemus montrouzieri Mulsant) on third instar nymph of Maconellicoccus hirsutus (green) at different temperature levels viz., 20°c, 25°c, 30°c and 35°c. total number of third instar nymph of M. hirsutus consumed by I larval instar of C. montrouzieri was 15.03, 9.44, 9.23, and 7.88 at 20°c, 25°c, 30°c and 35°c temperature levels respectively. corresponding values for II, III and IV larval instars of C. montrouzieri at 20°c, 25°c, 30°c and 35°c temperature levels were 30.77, 17.06, 19.90 and 10.44, 55.17, 43.04, 34.80 and 21.20 and 69.13, 58.78, 53.59 and 33.42, respectively. total number of third instar nymph of M. hirsutus consumed by male and female beetle of C. montrouzieri at 20°c, 25°c, 30°c and 35°c temperature levels was 450.00 and 517.47, 393.78 and 490.90, 234.00 and 312.20 and 223.70 and 316.06, respectively. however, in both the cases, similar trend was observed on weight basis but inverse trend was observed when per day consumption was taken into account.

A B S T R A C T The lable claimed insecticides were evaluated for their persistence and residual ... more A B S T R A C T The lable claimed insecticides were evaluated for their persistence and residual toxicity against groundnut jassids. All the evaluated insecticides proved toxic for Empoasca kerri Pruthi under laboratory conditions. The highest persistence toxicity was exhibited by imidacloprid 0.003 percent to the nymphs and adults of Empoasca kerri in term of PT values to the extent of 1459.63, 1431.49 and 1382.47, 1283.94 at first and second spray, respectively. On the basis of LT 50 values imidacloprid 0.003 per cent persisted in biologically active stage to the highest extent of 9.26, 8.77 and 6.83, 9.73 days against nymph and adult of Empoasca kerri at first and second spray, respectively. Imidacloprid 0.003 percent concentration showed comparatively higher percentage mortality and residual toxicity against nymph and adult of Empoasca kerri.

Journal of Entomological Research, 2017

Economic parameters of silkworm viz., Disease incidence (%), weight of 10 matured larvae (g), eff... more Economic parameters of silkworm viz., Disease incidence (%), weight of 10 matured larvae (g), effective rate of rearing (ERR) (%), single cocoon weight (g), single shell weight (g), cocoon-shell ratio (%), cocoon yield per 10,000 brushed larvae (Kg), silk filament length (m), silk filament weight (g) and denier of silkworm (Bombyx mori L.) fed on mulberry(Morus alba) leaves treated with various concentrations of nutritional ingredients, were determined. The economic parameters of silkworm (Bombyx mori L.) enhanced due to supplementation with 0.2 % ascorbic acid.(Vit. C). Leaves treated with NPK along with ascorbic acid (Vit. C) can be used to increase the silk yield in commercial silkworm rearing.

Journal of Entomological Research, 2016

Indian Journal of Entomology, 2017

Nutrition of mulberry has a vital role in sericulture as it improves the growth, development, hea... more Nutrition of mulberry has a vital role in sericulture as it improves the growth, development, health, feed consumption and conversion, thereby improving the commercial traits of mulberry silkworm Bombyx mori L., as it influences its growth and cocoon production. Hence, the effect of three biofertilizers viz., vermicompost, Phosphobacteria, Azotobacter and their mixture was studied on weight of larvae, disease incidence, coccon weight, single shell weight, coccon shell ratio, effective rate of rearing, cocoon yield, cocoon filament length and weight, and denier of silkworm. The results revealed that significantly high weight of ten matured larvae (35.26 g), single cocoon weight (1.72 g), single shell weight (0.34 g), cocoon shell ratio (19.76%), cocoon yield/10, 000 larvae brushed (17.00 kg), cocoon filament length (928 m), cocoon filament weight (0.275 g), denier (2.66), lower disease incidence (1.33%) and highest effective rate of rearing (98.66%) were obtained in larvae fed with leaves of variety V-1 applied with vermicompost, Azotobacter and Phosphobacteria in equal proportions.

Journal of Entomological Research, 2016

the lepidopterous pest viz., Helicoverpa armigera (hubner) passed through two generations while, ... more the lepidopterous pest viz., Helicoverpa armigera (hubner) passed through two generations while, Amsacta moorie (buttler), passed through one generation each during summer. the highest larval mortality of H. armigera during its two generations in a year was recorded due to unknown reason (13.15 per cent) followed by nuclear polyhydrosis virus (7.60 per cent) and an unidentified parasitoid (6.81 per cent). The egg sterility was observed to be 13.14 per cent and its pupal mortality was due to unknown reason (9.91 per cent). the highest larval mortality of A. moorie was recorded due to unknown reason (13.97 per cent) followed by egg sterility (13.33 per cent) and pupal mortality due to unknown reason (13.15 per cent).

Annals of Plant Protection Sciences, 2016

All insecticides was effective in reducing jassids and thrips population on groundnut and imidacl... more All insecticides was effective in reducing jassids and thrips population on groundnut and imidacloprid 0.003% and dimethoate 0.04% exhibited highest efficacy. Among the insecticidal treatments tested in field, imidacloprid showed significantly superior in controlling jassids and thrips population and thereby, reduction in leaf damage and increasing in yield. Highest incremental cost benefit ratio 1: 16.52 was observed in imidacloprid followed by dimethoate (1: 12.75) treatments.

European Heart Journal, 2015

A combination of variable expression, age-related penetrance, and unpredictable arrhythmic events... more A combination of variable expression, age-related penetrance, and unpredictable arrhythmic events complicates management of relatives of arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) patients. We aimed to (i) determine predictors of ARVD/C diagnosis and (ii) optimize arrhythmic risk stratification among first-degree relatives of ARVD/C patients. Methods and results Detailed phenotypic and outcome data of 274 first-degree relatives (46% male; 36.5 + 18.9 years) of 138 ARVD/C probands were obtained. Ninety-six (35%) relatives were diagnosed with ARVD/C according to 2010 Task Force Criteria (TFC). Siblings had a threefold increased risk of ARVD/C diagnosis compared with parents and children (odds ratio 3.11, P , 0.001). Multivariable logistic regression identified symptoms (P , 0.001), being a sibling (P , 0.001), the presence of a pathogenic mutation (P , 0.001), and female sex (P ¼ 0.010) as predictors of ARVD/C diagnosis. During 6.7 + 3.8 years of follow-up, 21 (8%) relatives experienced a sustained ventricular arrhythmia (cycle length 271 + 48 ms). While being a sibling was a predictor of ARVD/C diagnosis, neither relatedness to the proband (P ¼ 0.185) nor malignant family history (P ¼ 0.347) was significantly associated with arrhythmic events. Meeting TFC independent of family history criteria had higher prognostic value for arrhythmic events than conventional 2010 TFC, which include family history [area under the receiver operating characteristic curve 0.95 (95% CI 0.93-0.97) vs. 0.85 (95% CI 0.82-0.88), P , 0.001]. Conclusion One-third of first-degree relatives develop manifest ARVD/C. Siblings have highest risk of disease, even after correcting for age and sex. Fulfilment of TFC independent of family history is superior to conventional TFC for arrhythmic risk stratification of relatives.

Heart Rhythm, 2015

Endurance exercise is associated with adverse outcomes in patients with arrhythmogenic right vent... more Endurance exercise is associated with adverse outcomes in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C). Exercise recommendations for family members remain undetermined. The purposes of this study were to determine if (1) endurance exercise (Bethesda class C) and exercise intensity (metabolic equivalent hours per year [MET-Hr/year]) increase the likelihood of fulfilling 2010 Task Force Criteria and ventricular arrhythmias/implantable cardioverter-defibrillator shock (ventricular tachycardia/ventricular fibrillation [VT/VF]), and (2) exercise restriction to the American Heart Association (AHA) minimum goal for healthy adults is associated with favorable outcomes of at-risk family members. Twenty-eight family members of 10 probands inheriting a PKP2 mutation were interviewed about exercise from age 10. Exercise threshold to maintain overall health was based on the 2007 AHA guidelines of a minimum 390 to 650 MET-Hr/year. After adjustment for age, sex, and family membership, both participation in endurance athletics (odds ratio [OR] 7.4, P = .03) and higher-intensity exercise (OR = 4.2, P = .004) were associated with diagnosis (n = 13). Endurance athletes were also significantly more likely to develop VT/VF (n = 6, P = .02). Family members who restricted exercise at or below the upper bound of the AHA goal (≤650 MET-Hr/year) were significantly less likely to be diagnosed (OR = 0.07, P = .002) and had no VT/VF. At diagnosis and first VT/VF, family members had accumulated 2.8-fold (P = .002) and 3.5-fold (P = .03), respectively, greater MET-Hr exercise than the AHA-recommended minimum. Those who developed VT/VF had performed particularly high-intensity exercise in adolescence compared to unaffected family members (age 10-14: P = .04; age 14-19: P = .02). The results of this study suggest restricting unaffected desmosomal mutation carriers from endurance and high-intensity athletics but potentially not from AHA-recommended minimum levels of exercise for healthy adults.

Cardiac Electrophysiology Clinics, 2015

Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is rare cardiomyopathy associa... more Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is rare cardiomyopathy associated with life-threatening arrhythmias and increased risk of sudden cardiac death. In addition to mutations in desmosomal genes, environmental factors such as exercise have been implicated in the pathogenesis of the disease. Recent studies have shown that exercise may be associated with adverse outcomes in ARVD/C patients. Based on current evidence, ARVD/C patients are recommended to limit exercise irrespective of their mutation status. In addition, some studies have suggested the presence of an entirely acquired form of the disease caused by exercise that has been dubbed exercise-induced ARVD/C.

BMJ case reports, Jan 14, 2012

D34. PULMONARY HYPERTENSION: ENDPOINTS AND OUTCOMES, 2011

Page 1. / Thematic Poster Session / Wednesday, May 18/8:15 D34 PULMONARY HYPERTENSION: ENDPOINTS ... more Page 1. / Thematic Poster Session / Wednesday, May 18/8:15 D34 PULMONARY HYPERTENSION: ENDPOINTS AND OUTCOMES AM-4:30 PM / Area A, Hall B (Upper Level), Colorado Convention Center Pulmonary Hypertension ...

Case Reports, 2012

Benign cystic teratoma of lung is an extremely rare tumour, which was first described in literatu... more Benign cystic teratoma of lung is an extremely rare tumour, which was first described in literature by Mohr in 1839. Intrapulmonary teratoma is thought to be a derivative of the third endo-dermal pharyngeal pouch, which is an anlage of the thymus. The authors present a rare case of mature cystic teratoma in a young male involving the right upper lobe of the lung. Diagnosis is often missed and patients are treated for various infectious conditions. Treatment is complete resection for both benign and malignant teratomas and carries excellent prognosis. Benign cystic teratoma, if not excised may cause grave complications like life-threatening haemoptysis or malignant transformation with metastatic disease.

Journal of the American College of Cardiology, 2014

A study was conducted to observe the predatory potential of Cryptolaemus montrouzieri Mulsant) on... more A study was conducted to observe the predatory potential of Cryptolaemus montrouzieri Mulsant) on third instar nymph of Maconellicoccus hirsutus (green) at different temperature levels viz., 20°c, 25°c, 30°c and 35°c. total number of third instar nymph of M. hirsutus consumed by I larval instar of C. montrouzieri was 15.03, 9.44, 9.23, and 7.88 at 20°c, 25°c, 30°c and 35°c temperature levels respectively. corresponding values for II, III and IV larval instars of C. montrouzieri at 20°c, 25°c, 30°c and 35°c temperature levels were 30.77, 17.06, 19.90 and 10.44, 55.17, 43.04, 34.80 and 21.20 and 69.13, 58.78, 53.59 and 33.42, respectively. total number of third instar nymph of M. hirsutus consumed by male and female beetle of C. montrouzieri at 20°c, 25°c, 30°c and 35°c temperature levels was 450.00 and 517.47, 393.78 and 490.90, 234.00 and 312.20 and 223.70 and 316.06, respectively. however, in both the cases, similar trend was observed on weight basis but inverse trend was observed when per day consumption was taken into account.

A B S T R A C T The lable claimed insecticides were evaluated for their persistence and residual ... more A B S T R A C T The lable claimed insecticides were evaluated for their persistence and residual toxicity against groundnut jassids. All the evaluated insecticides proved toxic for Empoasca kerri Pruthi under laboratory conditions. The highest persistence toxicity was exhibited by imidacloprid 0.003 percent to the nymphs and adults of Empoasca kerri in term of PT values to the extent of 1459.63, 1431.49 and 1382.47, 1283.94 at first and second spray, respectively. On the basis of LT 50 values imidacloprid 0.003 per cent persisted in biologically active stage to the highest extent of 9.26, 8.77 and 6.83, 9.73 days against nymph and adult of Empoasca kerri at first and second spray, respectively. Imidacloprid 0.003 percent concentration showed comparatively higher percentage mortality and residual toxicity against nymph and adult of Empoasca kerri.